data_6FFK
# 
_entry.id   6FFK 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.299 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
PDB   6FFK         
WWPDB D_1200008233 
# 
_pdbx_database_related.db_name        PDB 
_pdbx_database_related.details        . 
_pdbx_database_related.db_id          3re0 
_pdbx_database_related.content_type   unspecified 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        6FFK 
_pdbx_database_status.recvd_initial_deposition_date   2018-01-08 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBE 
_pdbx_database_status.process_site                    PDBE 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Calderone, V.'          1 ? 
'Nativi, C.'             2 ? 
'Cantini, F.'            3 ? 
'Di Cesare Mannelli, L.' 4 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'ACS Med Chem Lett' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1948-5875 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            9 
_citation.language                  ? 
_citation.page_first                1094 
_citation.page_last                 1098 
_citation.title                     
'Interaction of Half Oxa-/Halfcis-Platin Complex with Human Superoxide Dismutase and Induced Reduction of Neurotoxicity.' 
_citation.year                      2018 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/acsmedchemlett.8b00199 
_citation.pdbx_database_id_PubMed   30429951 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Cantini, F.'            1 ? 
primary 'Calderone, V.'          2 ? 
primary 'Di Cesare Mannelli, L.' 3 ? 
primary 'Korsak, M.'             4 ? 
primary 'Gonnelli, L.'           5 ? 
primary 'Francesconi, O.'        6 ? 
primary 'Ghelardini, C.'         7 ? 
primary 'Banci, L.'              8 ? 
primary 'Nativi, C.'             9 ? 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   112.26 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     6FFK 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     156.850 
_cell.length_a_esd                 ? 
_cell.length_b                     35.370 
_cell.length_b_esd                 ? 
_cell.length_c                     114.590 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        16 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
# 
_symmetry.entry_id                         6FFK 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                5 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'C 1 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Superoxide dismutase [Cu-Zn]' 15827.561 4 1.15.1.1 ? ? 
'In the second dimer residues 68 to 78 and residues 125 to 140 show no density at all and so they have non been modeled' 
2 non-polymer syn 'PtCl2(1(R),2(R)-DACH)'        378.157   4 ?        ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Superoxide dismutase 1,hSod1' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;ATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERH
VGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ
;
_entity_poly.pdbx_seq_one_letter_code_can   
;ATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERH
VGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ
;
_entity_poly.pdbx_strand_id                 A,B,D,F 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ALA n 
1 2   THR n 
1 3   LYS n 
1 4   ALA n 
1 5   VAL n 
1 6   CYS n 
1 7   VAL n 
1 8   LEU n 
1 9   LYS n 
1 10  GLY n 
1 11  ASP n 
1 12  GLY n 
1 13  PRO n 
1 14  VAL n 
1 15  GLN n 
1 16  GLY n 
1 17  ILE n 
1 18  ILE n 
1 19  ASN n 
1 20  PHE n 
1 21  GLU n 
1 22  GLN n 
1 23  LYS n 
1 24  GLU n 
1 25  SER n 
1 26  ASN n 
1 27  GLY n 
1 28  PRO n 
1 29  VAL n 
1 30  LYS n 
1 31  VAL n 
1 32  TRP n 
1 33  GLY n 
1 34  SER n 
1 35  ILE n 
1 36  LYS n 
1 37  GLY n 
1 38  LEU n 
1 39  THR n 
1 40  GLU n 
1 41  GLY n 
1 42  LEU n 
1 43  HIS n 
1 44  GLY n 
1 45  PHE n 
1 46  HIS n 
1 47  VAL n 
1 48  HIS n 
1 49  GLU n 
1 50  PHE n 
1 51  GLY n 
1 52  ASP n 
1 53  ASN n 
1 54  THR n 
1 55  ALA n 
1 56  GLY n 
1 57  CYS n 
1 58  THR n 
1 59  SER n 
1 60  ALA n 
1 61  GLY n 
1 62  PRO n 
1 63  HIS n 
1 64  PHE n 
1 65  ASN n 
1 66  PRO n 
1 67  LEU n 
1 68  SER n 
1 69  ARG n 
1 70  LYS n 
1 71  HIS n 
1 72  GLY n 
1 73  GLY n 
1 74  PRO n 
1 75  LYS n 
1 76  ASP n 
1 77  GLU n 
1 78  GLU n 
1 79  ARG n 
1 80  HIS n 
1 81  VAL n 
1 82  GLY n 
1 83  ASP n 
1 84  LEU n 
1 85  GLY n 
1 86  ASN n 
1 87  VAL n 
1 88  THR n 
1 89  ALA n 
1 90  ASP n 
1 91  LYS n 
1 92  ASP n 
1 93  GLY n 
1 94  VAL n 
1 95  ALA n 
1 96  ASP n 
1 97  VAL n 
1 98  SER n 
1 99  ILE n 
1 100 GLU n 
1 101 ASP n 
1 102 SER n 
1 103 VAL n 
1 104 ILE n 
1 105 SER n 
1 106 LEU n 
1 107 SER n 
1 108 GLY n 
1 109 ASP n 
1 110 HIS n 
1 111 CYS n 
1 112 ILE n 
1 113 ILE n 
1 114 GLY n 
1 115 ARG n 
1 116 THR n 
1 117 LEU n 
1 118 VAL n 
1 119 VAL n 
1 120 HIS n 
1 121 GLU n 
1 122 LYS n 
1 123 ALA n 
1 124 ASP n 
1 125 ASP n 
1 126 LEU n 
1 127 GLY n 
1 128 LYS n 
1 129 GLY n 
1 130 GLY n 
1 131 ASN n 
1 132 GLU n 
1 133 GLU n 
1 134 SER n 
1 135 THR n 
1 136 LYS n 
1 137 THR n 
1 138 GLY n 
1 139 ASN n 
1 140 ALA n 
1 141 GLY n 
1 142 SER n 
1 143 ARG n 
1 144 LEU n 
1 145 ALA n 
1 146 CYS n 
1 147 GLY n 
1 148 VAL n 
1 149 ILE n 
1 150 GLY n 
1 151 ILE n 
1 152 ALA n 
1 153 GLN n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   153 
_entity_src_gen.gene_src_common_name               Human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 SOD1 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    SODC_HUMAN 
_struct_ref.pdbx_db_accession          P00441 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;ATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERH
VGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ
;
_struct_ref.pdbx_align_begin           2 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 6FFK A 1 ? 153 ? P00441 2 ? 154 ? 1 153 
2 1 6FFK B 1 ? 153 ? P00441 2 ? 154 ? 1 153 
3 1 6FFK D 1 ? 153 ? P00441 2 ? 154 ? 1 153 
4 1 6FFK F 1 ? 153 ? P00441 2 ? 154 ? 1 153 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                 ? 'C3 H7 N O2'       89.093  
ARG 'L-peptide linking' y ARGININE                ? 'C6 H15 N4 O2 1'   175.209 
ASN 'L-peptide linking' y ASPARAGINE              ? 'C4 H8 N2 O3'      132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'         ? 'C4 H7 N O4'       133.103 
CYS 'L-peptide linking' y CYSTEINE                ? 'C3 H7 N O2 S'     121.158 
D7Z non-polymer         . 'PtCl2(1(R),2(R)-DACH)' ? 'C6 H12 Cl2 N2 Pt' 378.157 
GLN 'L-peptide linking' y GLUTAMINE               ? 'C5 H10 N2 O3'     146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'         ? 'C5 H9 N O4'       147.129 
GLY 'peptide linking'   y GLYCINE                 ? 'C2 H5 N O2'       75.067  
HIS 'L-peptide linking' y HISTIDINE               ? 'C6 H10 N3 O2 1'   156.162 
ILE 'L-peptide linking' y ISOLEUCINE              ? 'C6 H13 N O2'      131.173 
LEU 'L-peptide linking' y LEUCINE                 ? 'C6 H13 N O2'      131.173 
LYS 'L-peptide linking' y LYSINE                  ? 'C6 H15 N2 O2 1'   147.195 
PHE 'L-peptide linking' y PHENYLALANINE           ? 'C9 H11 N O2'      165.189 
PRO 'L-peptide linking' y PROLINE                 ? 'C5 H9 N O2'       115.130 
SER 'L-peptide linking' y SERINE                  ? 'C3 H7 N O3'       105.093 
THR 'L-peptide linking' y THREONINE               ? 'C4 H9 N O3'       119.119 
TRP 'L-peptide linking' y TRYPTOPHAN              ? 'C11 H12 N2 O2'    204.225 
VAL 'L-peptide linking' y VALINE                  ? 'C5 H11 N O2'      117.146 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   6FFK 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                      ? 
_exptl_crystal.density_diffrn              ? 
_exptl_crystal.density_Matthews            2.32 
_exptl_crystal.density_method              ? 
_exptl_crystal.density_percent_sol         47.06 
_exptl_crystal.description                 ? 
_exptl_crystal.F_000                       ? 
_exptl_crystal.id                          1 
_exptl_crystal.preparation                 ? 
_exptl_crystal.size_max                    ? 
_exptl_crystal.size_mid                    ? 
_exptl_crystal.size_min                    ? 
_exptl_crystal.size_rad                    ? 
_exptl_crystal.colour_lustre               ? 
_exptl_crystal.colour_modifier             ? 
_exptl_crystal.colour_primary              ? 
_exptl_crystal.density_meas                ? 
_exptl_crystal.density_meas_esd            ? 
_exptl_crystal.density_meas_gt             ? 
_exptl_crystal.density_meas_lt             ? 
_exptl_crystal.density_meas_temp           ? 
_exptl_crystal.density_meas_temp_esd       ? 
_exptl_crystal.density_meas_temp_gt        ? 
_exptl_crystal.density_meas_temp_lt        ? 
_exptl_crystal.pdbx_crystal_image_url      ? 
_exptl_crystal.pdbx_crystal_image_format   ? 
_exptl_crystal.pdbx_mosaicity              ? 
_exptl_crystal.pdbx_mosaicity_esd          ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              7.0 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp            293 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1 M HEPES, 20% PEG 3350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
# 
_diffrn.ambient_environment    ? 
_diffrn.ambient_temp           100 
_diffrn.ambient_temp_details   ? 
_diffrn.ambient_temp_esd       ? 
_diffrn.crystal_id             1 
_diffrn.crystal_support        ? 
_diffrn.crystal_treatment      ? 
_diffrn.details                ? 
_diffrn.id                     1 
_diffrn.ambient_pressure       ? 
_diffrn.ambient_pressure_esd   ? 
_diffrn.ambient_pressure_gt    ? 
_diffrn.ambient_pressure_lt    ? 
_diffrn.ambient_temp_gt        ? 
_diffrn.ambient_temp_lt        ? 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS 6M-F' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2017-09-21 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.972 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'ESRF BEAMLINE ID30B' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.972 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   ID30B 
_diffrn_source.pdbx_synchrotron_site       ESRF 
# 
_reflns.B_iso_Wilson_estimate            38.78 
_reflns.entry_id                         6FFK 
_reflns.data_reduction_details           ? 
_reflns.data_reduction_method            ? 
_reflns.d_resolution_high                1.94 
_reflns.d_resolution_low                 40.0 
_reflns.details                          ? 
_reflns.limit_h_max                      ? 
_reflns.limit_h_min                      ? 
_reflns.limit_k_max                      ? 
_reflns.limit_k_min                      ? 
_reflns.limit_l_max                      ? 
_reflns.limit_l_min                      ? 
_reflns.number_all                       ? 
_reflns.number_obs                       82609 
_reflns.observed_criterion               ? 
_reflns.observed_criterion_F_max         ? 
_reflns.observed_criterion_F_min         ? 
_reflns.observed_criterion_I_max         ? 
_reflns.observed_criterion_I_min         ? 
_reflns.observed_criterion_sigma_F       0 
_reflns.observed_criterion_sigma_I       0 
_reflns.percent_possible_obs             98.0 
_reflns.R_free_details                   ? 
_reflns.Rmerge_F_all                     ? 
_reflns.Rmerge_F_obs                     ? 
_reflns.Friedel_coverage                 ? 
_reflns.number_gt                        ? 
_reflns.threshold_expression             ? 
_reflns.pdbx_redundancy                  3.4 
_reflns.pdbx_Rmerge_I_obs                0.062 
_reflns.pdbx_Rmerge_I_all                ? 
_reflns.pdbx_Rsym_value                  ? 
_reflns.pdbx_netI_over_av_sigmaI         ? 
_reflns.pdbx_netI_over_sigmaI            9.8 
_reflns.pdbx_res_netI_over_av_sigmaI_2   ? 
_reflns.pdbx_res_netI_over_sigmaI_2      ? 
_reflns.pdbx_chi_squared                 ? 
_reflns.pdbx_scaling_rejects             ? 
_reflns.pdbx_d_res_high_opt              ? 
_reflns.pdbx_d_res_low_opt               ? 
_reflns.pdbx_d_res_opt_method            ? 
_reflns.phase_calculation_details        ? 
_reflns.pdbx_Rrim_I_all                  ? 
_reflns.pdbx_Rpim_I_all                  ? 
_reflns.pdbx_d_opt                       ? 
_reflns.pdbx_number_measured_all         ? 
_reflns.pdbx_diffrn_id                   1 
_reflns.pdbx_ordinal                     1 
_reflns.pdbx_CC_half                     ? 
_reflns.pdbx_R_split                     ? 
# 
_reflns_shell.d_res_high                  1.95 
_reflns_shell.d_res_low                   2.0 
_reflns_shell.meanI_over_sigI_all         ? 
_reflns_shell.meanI_over_sigI_obs         ? 
_reflns_shell.number_measured_all         ? 
_reflns_shell.number_measured_obs         ? 
_reflns_shell.number_possible             ? 
_reflns_shell.number_unique_all           ? 
_reflns_shell.number_unique_obs           12658 
_reflns_shell.percent_possible_all        92.3 
_reflns_shell.percent_possible_obs        ? 
_reflns_shell.Rmerge_F_all                ? 
_reflns_shell.Rmerge_F_obs                ? 
_reflns_shell.Rmerge_I_all                ? 
_reflns_shell.Rmerge_I_obs                0.54 
_reflns_shell.meanI_over_sigI_gt          ? 
_reflns_shell.meanI_over_uI_all           ? 
_reflns_shell.meanI_over_uI_gt            ? 
_reflns_shell.number_measured_gt          ? 
_reflns_shell.number_unique_gt            ? 
_reflns_shell.percent_possible_gt         ? 
_reflns_shell.Rmerge_F_gt                 ? 
_reflns_shell.Rmerge_I_gt                 ? 
_reflns_shell.pdbx_redundancy             3.2 
_reflns_shell.pdbx_Rsym_value             ? 
_reflns_shell.pdbx_chi_squared            ? 
_reflns_shell.pdbx_netI_over_sigmaI_all   ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs   ? 
_reflns_shell.pdbx_Rrim_I_all             ? 
_reflns_shell.pdbx_Rpim_I_all             ? 
_reflns_shell.pdbx_rejects                ? 
_reflns_shell.pdbx_ordinal                1 
_reflns_shell.pdbx_diffrn_id              1 
_reflns_shell.pdbx_CC_half                ? 
_reflns_shell.pdbx_R_split                ? 
# 
_refine.aniso_B[1][1]                            2.03190 
_refine.aniso_B[1][2]                            0.00000 
_refine.aniso_B[1][3]                            2.33560 
_refine.aniso_B[2][2]                            -11.61590 
_refine.aniso_B[2][3]                            0.00000 
_refine.aniso_B[3][3]                            9.58400 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               63.83 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.934 
_refine.correlation_coeff_Fo_to_Fc_free          0.922 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 6FFK 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.94 
_refine.ls_d_res_low                             28.46 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     43129 
_refine.ls_number_reflns_R_free                  2157 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.8 
_refine.ls_percent_reflns_R_free                 5.000 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.227 
_refine.ls_R_factor_R_free                       0.256 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.226 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          0.000 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               0 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                0 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      3RE0 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   0.153 
_refine.pdbx_overall_SU_R_free_Blow_DPI          0.148 
_refine.pdbx_overall_SU_R_Blow_DPI               0.164 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             0.172 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_analyze.entry_id                        6FFK 
_refine_analyze.pdbx_refine_id                  'X-RAY DIFFRACTION' 
_refine_analyze.Luzzati_coordinate_error_free   ? 
_refine_analyze.Luzzati_coordinate_error_obs    0.35 
_refine_analyze.Luzzati_d_res_low_free          ? 
_refine_analyze.Luzzati_d_res_low_obs           ? 
_refine_analyze.Luzzati_sigma_a_free            ? 
_refine_analyze.Luzzati_sigma_a_free_details    ? 
_refine_analyze.Luzzati_sigma_a_obs             ? 
_refine_analyze.Luzzati_sigma_a_obs_details     ? 
_refine_analyze.number_disordered_residues      ? 
_refine_analyze.occupancy_sum_hydrogen          ? 
_refine_analyze.occupancy_sum_non_hydrogen      ? 
_refine_analyze.RG_d_res_high                   ? 
_refine_analyze.RG_d_res_low                    ? 
_refine_analyze.RG_free                         ? 
_refine_analyze.RG_work                         ? 
_refine_analyze.RG_free_work_ratio              ? 
_refine_analyze.pdbx_Luzzati_d_res_high_obs     ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         1 
_refine_hist.pdbx_number_atoms_protein        4050 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         40 
_refine_hist.number_atoms_solvent             0 
_refine_hist.number_atoms_total               4090 
_refine_hist.d_res_high                       1.94 
_refine_hist.d_res_low                        28.46 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.008 ? 4162 ? t_bond_d                  2.00  HARMONIC     
'X-RAY DIFFRACTION' ? 1.12  ? 5622 ? t_angle_deg               2.00  HARMONIC     
'X-RAY DIFFRACTION' ? ?     ? 1440 ? t_dihedral_angle_d        2.00  SINUSOIDAL   
'X-RAY DIFFRACTION' ? ?     ? ?    ? t_incorr_chiral_ct        ?     ?            
'X-RAY DIFFRACTION' ? ?     ? ?    ? t_pseud_angle             ?     ?            
'X-RAY DIFFRACTION' ? ?     ? ?    ? t_trig_c_planes           ?     ?            
'X-RAY DIFFRACTION' ? ?     ? 726  ? t_gen_planes              5.00  HARMONIC     
'X-RAY DIFFRACTION' ? ?     ? 4162 ? t_it                      20.00 HARMONIC     
'X-RAY DIFFRACTION' ? ?     ? 2    ? t_nbd                     5.00  SEMIHARMONIC 
'X-RAY DIFFRACTION' ? 2.92  ? ?    ? t_omega_torsion           ?     ?            
'X-RAY DIFFRACTION' ? 18.93 ? ?    ? t_other_torsion           ?     ?            
'X-RAY DIFFRACTION' ? ?     ? ?    ? t_improper_torsion        ?     ?            
'X-RAY DIFFRACTION' ? ?     ? 534  ? t_chiral_improper_torsion 5.00  SEMIHARMONIC 
'X-RAY DIFFRACTION' ? ?     ? ?    ? t_sum_occupancies         ?     ?            
'X-RAY DIFFRACTION' ? ?     ? ?    ? t_utility_distance        ?     ?            
'X-RAY DIFFRACTION' ? ?     ? ?    ? t_utility_angle           ?     ?            
'X-RAY DIFFRACTION' ? ?     ? ?    ? t_utility_torsion         ?     ?            
'X-RAY DIFFRACTION' ? ?     ? 4289 ? t_ideal_dist_contact      4.00  SEMIHARMONIC 
# 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.d_res_high                       1.94 
_refine_ls_shell.d_res_low                        2.00 
_refine_ls_shell.number_reflns_all                2793 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             140 
_refine_ls_shell.number_reflns_R_work             2653 
_refine_ls_shell.percent_reflns_obs               87.72 
_refine_ls_shell.percent_reflns_R_free            5.01 
_refine_ls_shell.R_factor_all                     0.2612 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free                  0.3226 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.2579 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
# 
_struct.entry_id                     6FFK 
_struct.title                        'Human apo-SOD1 bound to PtCl2(1R,2R-1,4-DACH' 
_struct.pdbx_descriptor              'Superoxide dismutase [Cu-Zn] (E.C.1.15.1.1)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        6FFK 
_struct_keywords.text            OXIDOREDUCTASE 
_struct_keywords.pdbx_keywords   OXIDOREDUCTASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 2 ? 
F N N 2 ? 
G N N 2 ? 
H N N 2 ? 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 ALA A 55  ? GLY A 61  ? ALA A 55  GLY A 61  5 ? 7 
HELX_P HELX_P2 AA2 ALA B 55  ? GLY B 61  ? ALA B 55  GLY B 61  5 ? 7 
HELX_P HELX_P3 AA3 ALA C 55  ? GLY C 61  ? ALA D 55  GLY D 61  5 ? 7 
HELX_P HELX_P4 AA4 SER C 107 ? CYS C 111 ? SER D 107 CYS D 111 5 ? 5 
HELX_P HELX_P5 AA5 CYS D 57  ? GLY D 61  ? CYS F 57  GLY F 61  5 ? 5 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
disulf1 disulf ? ? A CYS 57  SG ? ? ? 1_555 A CYS 146 SG  ? ? A CYS 57  A CYS 146 1_555 ? ? ? ? ? ? ? 2.063 ? 
disulf2 disulf ? ? B CYS 57  SG ? ? ? 1_555 B CYS 146 SG  ? ? B CYS 57  B CYS 146 1_555 ? ? ? ? ? ? ? 2.060 ? 
disulf3 disulf ? ? C CYS 57  SG ? ? ? 1_555 C CYS 146 SG  ? ? D CYS 57  D CYS 146 1_555 ? ? ? ? ? ? ? 2.055 ? 
disulf4 disulf ? ? D CYS 57  SG ? ? ? 1_555 D CYS 146 SG  ? ? F CYS 57  F CYS 146 1_555 ? ? ? ? ? ? ? 2.055 ? 
metalc1 metalc ? ? A CYS 111 SG ? ? ? 1_555 E D7Z .   PT8 ? ? A CYS 111 A D7Z 201 1_555 ? ? ? ? ? ? ? 2.341 ? 
metalc2 metalc ? ? B CYS 111 SG ? ? ? 1_555 F D7Z .   PT8 ? ? B CYS 111 B D7Z 201 1_555 ? ? ? ? ? ? ? 2.385 ? 
metalc3 metalc ? ? C CYS 111 SG ? ? ? 1_555 G D7Z .   PT8 ? ? D CYS 111 D D7Z 201 1_555 ? ? ? ? ? ? ? 2.260 ? 
metalc4 metalc ? ? D CYS 111 SG ? ? ? 1_555 H D7Z .   PT8 ? ? F CYS 111 F D7Z 201 1_555 ? ? ? ? ? ? ? 2.255 ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
metalc ? ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 4 ? 
AA3 ? 5 ? 
AA4 ? 4 ? 
AA5 ? 5 ? 
AA6 ? 4 ? 
AA7 ? 5 ? 
AA8 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA7 4 5 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ALA A 95  ? ASP A 101 ? ALA A 95  ASP A 101 
AA1 2 VAL A 29  ? LYS A 36  ? VAL A 29  LYS A 36  
AA1 3 GLN A 15  ? GLN A 22  ? GLN A 15  GLN A 22  
AA1 4 THR A 2   ? LYS A 9   ? THR A 2   LYS A 9   
AA1 5 GLY A 150 ? ALA A 152 ? GLY A 150 ALA A 152 
AA2 1 ASP A 83  ? ALA A 89  ? ASP A 83  ALA A 89  
AA2 2 GLY A 41  ? HIS A 48  ? GLY A 41  HIS A 48  
AA2 3 THR A 116 ? HIS A 120 ? THR A 116 HIS A 120 
AA2 4 ARG A 143 ? VAL A 148 ? ARG A 143 VAL A 148 
AA3 1 ALA B 95  ? ASP B 101 ? ALA B 95  ASP B 101 
AA3 2 VAL B 29  ? LYS B 36  ? VAL B 29  LYS B 36  
AA3 3 GLN B 15  ? GLN B 22  ? GLN B 15  GLN B 22  
AA3 4 THR B 2   ? LYS B 9   ? THR B 2   LYS B 9   
AA3 5 GLY B 150 ? ILE B 151 ? GLY B 150 ILE B 151 
AA4 1 ASP B 83  ? ALA B 89  ? ASP B 83  ALA B 89  
AA4 2 GLY B 41  ? HIS B 48  ? GLY B 41  HIS B 48  
AA4 3 THR B 116 ? HIS B 120 ? THR B 116 HIS B 120 
AA4 4 ARG B 143 ? VAL B 148 ? ARG B 143 VAL B 148 
AA5 1 ALA C 95  ? ASP C 101 ? ALA D 95  ASP D 101 
AA5 2 VAL C 29  ? LYS C 36  ? VAL D 29  LYS D 36  
AA5 3 GLN C 15  ? GLN C 22  ? GLN D 15  GLN D 22  
AA5 4 THR C 2   ? LEU C 8   ? THR D 2   LEU D 8   
AA5 5 GLY C 150 ? ILE C 151 ? GLY D 150 ILE D 151 
AA6 1 ASP C 83  ? ALA C 89  ? ASP D 83  ALA D 89  
AA6 2 GLY C 41  ? HIS C 48  ? GLY D 41  HIS D 48  
AA6 3 THR C 116 ? HIS C 120 ? THR D 116 HIS D 120 
AA6 4 ARG C 143 ? VAL C 148 ? ARG D 143 VAL D 148 
AA7 1 ALA D 95  ? ASP D 101 ? ALA F 95  ASP F 101 
AA7 2 VAL D 29  ? LYS D 36  ? VAL F 29  LYS F 36  
AA7 3 GLN D 15  ? GLN D 22  ? GLN F 15  GLN F 22  
AA7 4 THR D 2   ? LEU D 8   ? THR F 2   LEU F 8   
AA7 5 GLY D 150 ? ILE D 151 ? GLY F 150 ILE F 151 
AA8 1 ASP D 83  ? ALA D 89  ? ASP F 83  ALA F 89  
AA8 2 GLY D 41  ? HIS D 48  ? GLY F 41  HIS F 48  
AA8 3 THR D 116 ? HIS D 120 ? THR F 116 HIS F 120 
AA8 4 ARG D 143 ? VAL D 148 ? ARG F 143 VAL F 148 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ASP A 101 ? O ASP A 101 N VAL A 29  ? N VAL A 29  
AA1 2 3 O TRP A 32  ? O TRP A 32  N ASN A 19  ? N ASN A 19  
AA1 3 4 O PHE A 20  ? O PHE A 20  N ALA A 4   ? N ALA A 4   
AA1 4 5 N LYS A 3   ? N LYS A 3   O ALA A 152 ? O ALA A 152 
AA2 1 2 O GLY A 85  ? O GLY A 85  N PHE A 45  ? N PHE A 45  
AA2 2 3 N HIS A 48  ? N HIS A 48  O THR A 116 ? O THR A 116 
AA2 3 4 N VAL A 119 ? N VAL A 119 O ALA A 145 ? O ALA A 145 
AA3 1 2 O ILE B 99  ? O ILE B 99  N VAL B 31  ? N VAL B 31  
AA3 2 3 O TRP B 32  ? O TRP B 32  N ASN B 19  ? N ASN B 19  
AA3 3 4 O ILE B 18  ? O ILE B 18  N CYS B 6   ? N CYS B 6   
AA3 4 5 N VAL B 5   ? N VAL B 5   O GLY B 150 ? O GLY B 150 
AA4 1 2 O GLY B 85  ? O GLY B 85  N PHE B 45  ? N PHE B 45  
AA4 2 3 N HIS B 48  ? N HIS B 48  O THR B 116 ? O THR B 116 
AA4 3 4 N VAL B 119 ? N VAL B 119 O ALA B 145 ? O ALA B 145 
AA5 1 2 O ILE C 99  ? O ILE D 99  N VAL C 31  ? N VAL D 31  
AA5 2 3 O TRP C 32  ? O TRP D 32  N ASN C 19  ? N ASN D 19  
AA5 3 4 O ILE C 18  ? O ILE D 18  N CYS C 6   ? N CYS D 6   
AA5 4 5 N VAL C 5   ? N VAL D 5   O GLY C 150 ? O GLY D 150 
AA6 1 2 O GLY C 85  ? O GLY D 85  N PHE C 45  ? N PHE D 45  
AA6 2 3 N HIS C 48  ? N HIS D 48  O THR C 116 ? O THR D 116 
AA6 3 4 N LEU C 117 ? N LEU D 117 O GLY C 147 ? O GLY D 147 
AA7 1 2 O ILE D 99  ? O ILE F 99  N VAL D 31  ? N VAL F 31  
AA7 2 3 O TRP D 32  ? O TRP F 32  N ASN D 19  ? N ASN F 19  
AA7 3 4 O GLY D 16  ? O GLY F 16  N LEU D 8   ? N LEU F 8   
AA7 4 5 N VAL D 5   ? N VAL F 5   O GLY D 150 ? O GLY F 150 
AA8 1 2 O VAL D 87  ? O VAL F 87  N HIS D 43  ? N HIS F 43  
AA8 2 3 N HIS D 48  ? N HIS F 48  O THR D 116 ? O THR F 116 
AA8 3 4 N LEU D 117 ? N LEU F 117 O GLY D 147 ? O GLY F 147 
# 
loop_
_struct_site.id 
_struct_site.pdbx_evidence_code 
_struct_site.pdbx_auth_asym_id 
_struct_site.pdbx_auth_comp_id 
_struct_site.pdbx_auth_seq_id 
_struct_site.pdbx_auth_ins_code 
_struct_site.pdbx_num_residues 
_struct_site.details 
AC1 Software A D7Z 201 ? 4 'binding site for residue D7Z A 201' 
AC2 Software B D7Z 201 ? 5 'binding site for residue D7Z B 201' 
AC3 Software D D7Z 201 ? 4 'binding site for residue D7Z D 201' 
AC4 Software F D7Z 201 ? 5 'binding site for residue D7Z F 201' 
# 
loop_
_struct_site_gen.id 
_struct_site_gen.site_id 
_struct_site_gen.pdbx_num_res 
_struct_site_gen.label_comp_id 
_struct_site_gen.label_asym_id 
_struct_site_gen.label_seq_id 
_struct_site_gen.pdbx_auth_ins_code 
_struct_site_gen.auth_comp_id 
_struct_site_gen.auth_asym_id 
_struct_site_gen.auth_seq_id 
_struct_site_gen.label_atom_id 
_struct_site_gen.label_alt_id 
_struct_site_gen.symmetry 
_struct_site_gen.details 
1  AC1 4 LEU A 106 ? LEU A 106 . ? 1_555 ? 
2  AC1 4 SER A 107 ? SER A 107 . ? 1_555 ? 
3  AC1 4 CYS A 111 ? CYS A 111 . ? 1_555 ? 
4  AC1 4 ILE A 113 ? ILE A 113 . ? 1_555 ? 
5  AC2 5 LEU B 106 ? LEU B 106 . ? 1_555 ? 
6  AC2 5 SER B 107 ? SER B 107 . ? 1_555 ? 
7  AC2 5 GLY B 108 ? GLY B 108 . ? 1_555 ? 
8  AC2 5 CYS B 111 ? CYS B 111 . ? 1_555 ? 
9  AC2 5 ILE B 113 ? ILE B 113 . ? 1_555 ? 
10 AC3 4 LEU C 106 ? LEU D 106 . ? 1_555 ? 
11 AC3 4 CYS C 111 ? CYS D 111 . ? 1_555 ? 
12 AC3 4 ILE C 113 ? ILE D 113 . ? 1_555 ? 
13 AC3 4 ARG C 115 ? ARG D 115 . ? 1_555 ? 
14 AC4 5 LEU D 106 ? LEU F 106 . ? 1_555 ? 
15 AC4 5 SER D 107 ? SER F 107 . ? 1_555 ? 
16 AC4 5 GLY D 108 ? GLY F 108 . ? 1_555 ? 
17 AC4 5 CYS D 111 ? CYS F 111 . ? 1_555 ? 
18 AC4 5 ILE D 113 ? ILE F 113 . ? 1_555 ? 
# 
_atom_sites.entry_id                    6FFK 
_atom_sites.fract_transf_matrix[1][1]   0.006376 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.002610 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.028273 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.009430 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
# 
loop_
_atom_type.symbol 
C  
CL 
N  
O  
PT 
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . ALA A 1 1   ? -3.372  -30.082 -28.386 1.00 86.53  ? 1   ALA A N   1 
ATOM   2    C  CA  . ALA A 1 1   ? -2.147  -29.612 -27.743 1.00 83.32  ? 1   ALA A CA  1 
ATOM   3    C  C   . ALA A 1 1   ? -1.431  -28.549 -28.594 1.00 82.85  ? 1   ALA A C   1 
ATOM   4    O  O   . ALA A 1 1   ? -0.850  -28.875 -29.637 1.00 82.68  ? 1   ALA A O   1 
ATOM   5    C  CB  . ALA A 1 1   ? -1.217  -30.789 -27.463 1.00 85.21  ? 1   ALA A CB  1 
ATOM   6    N  N   . THR A 1 2   ? -1.487  -27.273 -28.154 1.00 75.33  ? 2   THR A N   1 
ATOM   7    C  CA  . THR A 1 2   ? -0.846  -26.169 -28.875 1.00 71.31  ? 2   THR A CA  1 
ATOM   8    C  C   . THR A 1 2   ? 0.669   -26.213 -28.635 1.00 70.29  ? 2   THR A C   1 
ATOM   9    O  O   . THR A 1 2   ? 1.129   -26.489 -27.523 1.00 68.87  ? 2   THR A O   1 
ATOM   10   C  CB  . THR A 1 2   ? -1.529  -24.813 -28.603 1.00 78.48  ? 2   THR A CB  1 
ATOM   11   O  OG1 . THR A 1 2   ? -1.050  -23.840 -29.529 1.00 77.15  ? 2   THR A OG1 1 
ATOM   12   C  CG2 . THR A 1 2   ? -1.379  -24.325 -27.167 1.00 75.72  ? 2   THR A CG2 1 
ATOM   13   N  N   . LYS A 1 3   ? 1.430   -26.021 -29.719 1.00 63.65  ? 3   LYS A N   1 
ATOM   14   C  CA  . LYS A 1 3   ? 2.879   -26.103 -29.730 1.00 61.02  ? 3   LYS A CA  1 
ATOM   15   C  C   . LYS A 1 3   ? 3.528   -24.805 -30.177 1.00 60.42  ? 3   LYS A C   1 
ATOM   16   O  O   . LYS A 1 3   ? 3.044   -24.135 -31.094 1.00 58.92  ? 3   LYS A O   1 
ATOM   17   C  CB  . LYS A 1 3   ? 3.330   -27.256 -30.643 1.00 65.13  ? 3   LYS A CB  1 
ATOM   18   C  CG  . LYS A 1 3   ? 4.132   -28.337 -29.932 1.00 82.96  ? 3   LYS A CG  1 
ATOM   19   C  CD  . LYS A 1 3   ? 4.770   -29.303 -30.925 1.00 92.93  ? 3   LYS A CD  1 
ATOM   20   C  CE  . LYS A 1 3   ? 5.648   -30.328 -30.246 1.00 104.06 ? 3   LYS A CE  1 
ATOM   21   N  NZ  . LYS A 1 3   ? 6.330   -31.212 -31.228 1.00 113.11 ? 3   LYS A NZ  1 
ATOM   22   N  N   . ALA A 1 4   ? 4.644   -24.464 -29.527 1.00 54.67  ? 4   ALA A N   1 
ATOM   23   C  CA  . ALA A 1 4   ? 5.438   -23.290 -29.860 1.00 51.78  ? 4   ALA A CA  1 
ATOM   24   C  C   . ALA A 1 4   ? 6.927   -23.659 -29.939 1.00 54.80  ? 4   ALA A C   1 
ATOM   25   O  O   . ALA A 1 4   ? 7.346   -24.685 -29.393 1.00 55.97  ? 4   ALA A O   1 
ATOM   26   C  CB  . ALA A 1 4   ? 5.195   -22.176 -28.853 1.00 51.00  ? 4   ALA A CB  1 
ATOM   27   N  N   . VAL A 1 5   ? 7.717   -22.849 -30.649 1.00 48.93  ? 5   VAL A N   1 
ATOM   28   C  CA  . VAL A 1 5   ? 9.148   -23.103 -30.812 1.00 48.09  ? 5   VAL A CA  1 
ATOM   29   C  C   . VAL A 1 5   ? 9.928   -21.783 -30.821 1.00 49.71  ? 5   VAL A C   1 
ATOM   30   O  O   . VAL A 1 5   ? 9.391   -20.743 -31.214 1.00 49.27  ? 5   VAL A O   1 
ATOM   31   C  CB  . VAL A 1 5   ? 9.419   -24.004 -32.066 1.00 53.18  ? 5   VAL A CB  1 
ATOM   32   C  CG1 . VAL A 1 5   ? 9.196   -23.251 -33.375 1.00 52.79  ? 5   VAL A CG1 1 
ATOM   33   C  CG2 . VAL A 1 5   ? 10.807  -24.652 -32.030 1.00 53.29  ? 5   VAL A CG2 1 
ATOM   34   N  N   . CYS A 1 6   ? 11.185  -21.832 -30.385 1.00 45.89  ? 6   CYS A N   1 
ATOM   35   C  CA  . CYS A 1 6   ? 12.065  -20.676 -30.373 1.00 45.02  ? 6   CYS A CA  1 
ATOM   36   C  C   . CYS A 1 6   ? 13.481  -21.047 -30.790 1.00 47.77  ? 6   CYS A C   1 
ATOM   37   O  O   . CYS A 1 6   ? 14.067  -21.997 -30.268 1.00 47.61  ? 6   CYS A O   1 
ATOM   38   C  CB  . CYS A 1 6   ? 12.041  -19.972 -29.022 1.00 45.27  ? 6   CYS A CB  1 
ATOM   39   S  SG  . CYS A 1 6   ? 13.105  -18.512 -28.941 1.00 48.95  ? 6   CYS A SG  1 
ATOM   40   N  N   . VAL A 1 7   ? 14.015  -20.305 -31.760 1.00 45.16  ? 7   VAL A N   1 
ATOM   41   C  CA  . VAL A 1 7   ? 15.373  -20.487 -32.261 1.00 44.86  ? 7   VAL A CA  1 
ATOM   42   C  C   . VAL A 1 7   ? 16.200  -19.359 -31.666 1.00 48.59  ? 7   VAL A C   1 
ATOM   43   O  O   . VAL A 1 7   ? 15.934  -18.189 -31.947 1.00 47.03  ? 7   VAL A O   1 
ATOM   44   C  CB  . VAL A 1 7   ? 15.462  -20.544 -33.809 1.00 48.05  ? 7   VAL A CB  1 
ATOM   45   C  CG1 . VAL A 1 7   ? 16.900  -20.798 -34.256 1.00 48.30  ? 7   VAL A CG1 1 
ATOM   46   C  CG2 . VAL A 1 7   ? 14.539  -21.619 -34.369 1.00 48.44  ? 7   VAL A CG2 1 
ATOM   47   N  N   . LEU A 1 8   ? 17.153  -19.715 -30.794 1.00 47.47  ? 8   LEU A N   1 
ATOM   48   C  CA  . LEU A 1 8   ? 18.022  -18.769 -30.098 1.00 47.87  ? 8   LEU A CA  1 
ATOM   49   C  C   . LEU A 1 8   ? 19.269  -18.486 -30.925 1.00 51.45  ? 8   LEU A C   1 
ATOM   50   O  O   . LEU A 1 8   ? 19.944  -19.416 -31.365 1.00 51.90  ? 8   LEU A O   1 
ATOM   51   C  CB  . LEU A 1 8   ? 18.410  -19.280 -28.682 1.00 48.90  ? 8   LEU A CB  1 
ATOM   52   C  CG  . LEU A 1 8   ? 17.312  -19.410 -27.585 1.00 54.13  ? 8   LEU A CG  1 
ATOM   53   C  CD1 . LEU A 1 8   ? 16.632  -18.099 -27.295 1.00 52.78  ? 8   LEU A CD1 1 
ATOM   54   C  CD2 . LEU A 1 8   ? 16.290  -20.489 -27.904 1.00 58.72  ? 8   LEU A CD2 1 
ATOM   55   N  N   . LYS A 1 9   ? 19.538  -17.194 -31.169 1.00 47.48  ? 9   LYS A N   1 
ATOM   56   C  CA  . LYS A 1 9   ? 20.684  -16.695 -31.921 1.00 49.22  ? 9   LYS A CA  1 
ATOM   57   C  C   . LYS A 1 9   ? 21.130  -15.353 -31.354 1.00 52.65  ? 9   LYS A C   1 
ATOM   58   O  O   . LYS A 1 9   ? 20.306  -14.601 -30.824 1.00 49.66  ? 9   LYS A O   1 
ATOM   59   C  CB  . LYS A 1 9   ? 20.367  -16.582 -33.428 1.00 51.63  ? 9   LYS A CB  1 
ATOM   60   C  CG  . LYS A 1 9   ? 20.619  -17.882 -34.173 1.00 72.33  ? 9   LYS A CG  1 
ATOM   61   C  CD  . LYS A 1 9   ? 20.414  -17.752 -35.673 1.00 87.53  ? 9   LYS A CD  1 
ATOM   62   C  CE  . LYS A 1 9   ? 20.241  -19.092 -36.357 1.00 98.28  ? 9   LYS A CE  1 
ATOM   63   N  NZ  . LYS A 1 9   ? 21.474  -19.924 -36.301 1.00 107.14 ? 9   LYS A NZ  1 
ATOM   64   N  N   . GLY A 1 10  ? 22.425  -15.080 -31.471 1.00 50.97  ? 10  GLY A N   1 
ATOM   65   C  CA  . GLY A 1 10  ? 23.044  -13.848 -30.997 1.00 52.23  ? 10  GLY A CA  1 
ATOM   66   C  C   . GLY A 1 10  ? 24.242  -13.418 -31.821 1.00 59.20  ? 10  GLY A C   1 
ATOM   67   O  O   . GLY A 1 10  ? 24.427  -13.886 -32.949 1.00 59.65  ? 10  GLY A O   1 
ATOM   68   N  N   . ASP A 1 11  ? 25.046  -12.493 -31.265 1.00 58.00  ? 11  ASP A N   1 
ATOM   69   C  CA  . ASP A 1 11  ? 26.253  -11.966 -31.902 1.00 61.07  ? 11  ASP A CA  1 
ATOM   70   C  C   . ASP A 1 11  ? 27.475  -12.843 -31.601 1.00 66.23  ? 11  ASP A C   1 
ATOM   71   O  O   . ASP A 1 11  ? 28.517  -12.687 -32.235 1.00 68.77  ? 11  ASP A O   1 
ATOM   72   C  CB  . ASP A 1 11  ? 26.495  -10.500 -31.483 1.00 64.56  ? 11  ASP A CB  1 
ATOM   73   C  CG  . ASP A 1 11  ? 25.492  -9.511  -32.064 1.00 81.17  ? 11  ASP A CG  1 
ATOM   74   O  OD1 . ASP A 1 11  ? 25.220  -9.582  -33.291 1.00 82.91  ? 11  ASP A OD1 1 
ATOM   75   O  OD2 . ASP A 1 11  ? 24.994  -8.657  -31.300 1.00 88.65  ? 11  ASP A OD2 1 
ATOM   76   N  N   . GLY A 1 12  ? 27.319  -13.757 -30.647 1.00 60.65  ? 12  GLY A N   1 
ATOM   77   C  CA  . GLY A 1 12  ? 28.349  -14.693 -30.214 1.00 60.97  ? 12  GLY A CA  1 
ATOM   78   C  C   . GLY A 1 12  ? 28.122  -16.109 -30.714 1.00 61.72  ? 12  GLY A C   1 
ATOM   79   O  O   . GLY A 1 12  ? 27.395  -16.307 -31.693 1.00 58.72  ? 12  GLY A O   1 
ATOM   80   N  N   . PRO A 1 13  ? 28.701  -17.132 -30.037 1.00 59.22  ? 13  PRO A N   1 
ATOM   81   C  CA  . PRO A 1 13  ? 28.527  -18.518 -30.512 1.00 59.37  ? 13  PRO A CA  1 
ATOM   82   C  C   . PRO A 1 13  ? 27.269  -19.227 -29.982 1.00 60.73  ? 13  PRO A C   1 
ATOM   83   O  O   . PRO A 1 13  ? 26.998  -20.370 -30.362 1.00 59.88  ? 13  PRO A O   1 
ATOM   84   C  CB  . PRO A 1 13  ? 29.804  -19.199 -30.012 1.00 63.32  ? 13  PRO A CB  1 
ATOM   85   C  CG  . PRO A 1 13  ? 30.083  -18.505 -28.729 1.00 67.41  ? 13  PRO A CG  1 
ATOM   86   C  CD  . PRO A 1 13  ? 29.629  -17.079 -28.885 1.00 61.96  ? 13  PRO A CD  1 
ATOM   87   N  N   . VAL A 1 14  ? 26.507  -18.556 -29.106 1.00 56.67  ? 14  VAL A N   1 
ATOM   88   C  CA  . VAL A 1 14  ? 25.311  -19.126 -28.490 1.00 55.39  ? 14  VAL A CA  1 
ATOM   89   C  C   . VAL A 1 14  ? 24.198  -19.343 -29.512 1.00 57.99  ? 14  VAL A C   1 
ATOM   90   O  O   . VAL A 1 14  ? 23.746  -18.390 -30.146 1.00 56.24  ? 14  VAL A O   1 
ATOM   91   C  CB  . VAL A 1 14  ? 24.820  -18.334 -27.250 1.00 57.92  ? 14  VAL A CB  1 
ATOM   92   C  CG1 . VAL A 1 14  ? 23.662  -19.054 -26.562 1.00 56.83  ? 14  VAL A CG1 1 
ATOM   93   C  CG2 . VAL A 1 14  ? 25.954  -18.090 -26.264 1.00 58.64  ? 14  VAL A CG2 1 
ATOM   94   N  N   . GLN A 1 15  ? 23.785  -20.614 -29.674 1.00 54.65  ? 15  GLN A N   1 
ATOM   95   C  CA  . GLN A 1 15  ? 22.687  -21.035 -30.544 1.00 53.29  ? 15  GLN A CA  1 
ATOM   96   C  C   . GLN A 1 15  ? 21.917  -22.210 -29.924 1.00 56.72  ? 15  GLN A C   1 
ATOM   97   O  O   . GLN A 1 15  ? 22.516  -23.129 -29.366 1.00 58.58  ? 15  GLN A O   1 
ATOM   98   C  CB  . GLN A 1 15  ? 23.130  -21.297 -32.005 1.00 55.56  ? 15  GLN A CB  1 
ATOM   99   C  CG  . GLN A 1 15  ? 24.137  -22.416 -32.202 1.00 68.71  ? 15  GLN A CG  1 
ATOM   100  C  CD  . GLN A 1 15  ? 24.448  -22.661 -33.657 1.00 86.76  ? 15  GLN A CD  1 
ATOM   101  O  OE1 . GLN A 1 15  ? 23.860  -23.534 -34.304 1.00 81.12  ? 15  GLN A OE1 1 
ATOM   102  N  NE2 . GLN A 1 15  ? 25.388  -21.903 -34.202 1.00 78.44  ? 15  GLN A NE2 1 
ATOM   103  N  N   . GLY A 1 16  ? 20.600  -22.139 -29.980 1.00 51.39  ? 16  GLY A N   1 
ATOM   104  C  CA  . GLY A 1 16  ? 19.751  -23.173 -29.406 1.00 51.54  ? 16  GLY A CA  1 
ATOM   105  C  C   . GLY A 1 16  ? 18.367  -23.288 -30.005 1.00 53.53  ? 16  GLY A C   1 
ATOM   106  O  O   . GLY A 1 16  ? 17.923  -22.401 -30.739 1.00 51.80  ? 16  GLY A O   1 
ATOM   107  N  N   . ILE A 1 17  ? 17.695  -24.411 -29.718 1.00 50.50  ? 17  ILE A N   1 
ATOM   108  C  CA  . ILE A 1 17  ? 16.320  -24.690 -30.145 1.00 49.73  ? 17  ILE A CA  1 
ATOM   109  C  C   . ILE A 1 17  ? 15.522  -25.038 -28.891 1.00 53.63  ? 17  ILE A C   1 
ATOM   110  O  O   . ILE A 1 17  ? 15.918  -25.936 -28.143 1.00 54.19  ? 17  ILE A O   1 
ATOM   111  C  CB  . ILE A 1 17  ? 16.207  -25.775 -31.262 1.00 54.52  ? 17  ILE A CB  1 
ATOM   112  C  CG1 . ILE A 1 17  ? 16.873  -25.296 -32.583 1.00 54.77  ? 17  ILE A CG1 1 
ATOM   113  C  CG2 . ILE A 1 17  ? 14.718  -26.175 -31.495 1.00 54.12  ? 17  ILE A CG2 1 
ATOM   114  C  CD1 . ILE A 1 17  ? 17.154  -26.376 -33.602 1.00 64.09  ? 17  ILE A CD1 1 
ATOM   115  N  N   . ILE A 1 18  ? 14.432  -24.297 -28.637 1.00 48.47  ? 18  ILE A N   1 
ATOM   116  C  CA  . ILE A 1 18  ? 13.590  -24.520 -27.461 1.00 48.07  ? 18  ILE A CA  1 
ATOM   117  C  C   . ILE A 1 18  ? 12.141  -24.748 -27.898 1.00 52.07  ? 18  ILE A C   1 
ATOM   118  O  O   . ILE A 1 18  ? 11.603  -23.967 -28.676 1.00 50.35  ? 18  ILE A O   1 
ATOM   119  C  CB  . ILE A 1 18  ? 13.740  -23.377 -26.410 1.00 49.22  ? 18  ILE A CB  1 
ATOM   120  C  CG1 . ILE A 1 18  ? 15.187  -23.278 -25.819 1.00 49.83  ? 18  ILE A CG1 1 
ATOM   121  C  CG2 . ILE A 1 18  ? 12.689  -23.461 -25.312 1.00 48.61  ? 18  ILE A CG2 1 
ATOM   122  C  CD1 . ILE A 1 18  ? 15.761  -24.485 -24.974 1.00 53.83  ? 18  ILE A CD1 1 
ATOM   123  N  N   . ASN A 1 19  ? 11.530  -25.829 -27.399 1.00 49.70  ? 19  ASN A N   1 
ATOM   124  C  CA  . ASN A 1 19  ? 10.155  -26.218 -27.698 1.00 50.26  ? 19  ASN A CA  1 
ATOM   125  C  C   . ASN A 1 19  ? 9.248   -25.876 -26.521 1.00 54.65  ? 19  ASN A C   1 
ATOM   126  O  O   . ASN A 1 19  ? 9.702   -25.845 -25.374 1.00 53.76  ? 19  ASN A O   1 
ATOM   127  C  CB  . ASN A 1 19  ? 10.078  -27.718 -28.002 1.00 51.92  ? 19  ASN A CB  1 
ATOM   128  C  CG  . ASN A 1 19  ? 11.061  -28.184 -29.052 1.00 64.84  ? 19  ASN A CG  1 
ATOM   129  O  OD1 . ASN A 1 19  ? 12.163  -28.662 -28.744 1.00 58.61  ? 19  ASN A OD1 1 
ATOM   130  N  ND2 . ASN A 1 19  ? 10.690  -28.046 -30.313 1.00 52.52  ? 19  ASN A ND2 1 
ATOM   131  N  N   . PHE A 1 20  ? 7.972   -25.600 -26.811 1.00 51.82  ? 20  PHE A N   1 
ATOM   132  C  CA  . PHE A 1 20  ? 6.951   -25.300 -25.806 1.00 51.38  ? 20  PHE A CA  1 
ATOM   133  C  C   . PHE A 1 20  ? 5.717   -26.109 -26.166 1.00 57.76  ? 20  PHE A C   1 
ATOM   134  O  O   . PHE A 1 20  ? 5.320   -26.117 -27.331 1.00 57.57  ? 20  PHE A O   1 
ATOM   135  C  CB  . PHE A 1 20  ? 6.602   -23.801 -25.775 1.00 51.18  ? 20  PHE A CB  1 
ATOM   136  C  CG  . PHE A 1 20  ? 7.721   -22.847 -25.438 1.00 51.05  ? 20  PHE A CG  1 
ATOM   137  C  CD1 . PHE A 1 20  ? 8.571   -22.366 -26.429 1.00 53.53  ? 20  PHE A CD1 1 
ATOM   138  C  CD2 . PHE A 1 20  ? 7.893   -22.385 -24.136 1.00 52.53  ? 20  PHE A CD2 1 
ATOM   139  C  CE1 . PHE A 1 20  ? 9.601   -21.470 -26.118 1.00 53.30  ? 20  PHE A CE1 1 
ATOM   140  C  CE2 . PHE A 1 20  ? 8.916   -21.483 -23.826 1.00 54.27  ? 20  PHE A CE2 1 
ATOM   141  C  CZ  . PHE A 1 20  ? 9.763   -21.029 -24.820 1.00 52.32  ? 20  PHE A CZ  1 
ATOM   142  N  N   . GLU A 1 21  ? 5.126   -26.808 -25.186 1.00 56.98  ? 21  GLU A N   1 
ATOM   143  C  CA  . GLU A 1 21  ? 3.917   -27.598 -25.415 1.00 59.40  ? 21  GLU A CA  1 
ATOM   144  C  C   . GLU A 1 21  ? 2.932   -27.436 -24.273 1.00 65.72  ? 21  GLU A C   1 
ATOM   145  O  O   . GLU A 1 21  ? 3.287   -27.660 -23.116 1.00 65.66  ? 21  GLU A O   1 
ATOM   146  C  CB  . GLU A 1 21  ? 4.240   -29.081 -25.667 1.00 63.00  ? 21  GLU A CB  1 
ATOM   147  C  CG  . GLU A 1 21  ? 3.062   -29.870 -26.221 1.00 75.57  ? 21  GLU A CG  1 
ATOM   148  C  CD  . GLU A 1 21  ? 3.276   -31.364 -26.366 1.00 99.09  ? 21  GLU A CD  1 
ATOM   149  O  OE1 . GLU A 1 21  ? 3.536   -32.037 -25.341 1.00 92.58  ? 21  GLU A OE1 1 
ATOM   150  O  OE2 . GLU A 1 21  ? 3.164   -31.866 -27.508 1.00 91.30  ? 21  GLU A OE2 1 
ATOM   151  N  N   . GLN A 1 22  ? 1.688   -27.061 -24.605 1.00 64.19  ? 22  GLN A N   1 
ATOM   152  C  CA  . GLN A 1 22  ? 0.610   -26.887 -23.637 1.00 65.59  ? 22  GLN A CA  1 
ATOM   153  C  C   . GLN A 1 22  ? -0.605  -27.673 -24.126 1.00 74.39  ? 22  GLN A C   1 
ATOM   154  O  O   . GLN A 1 22  ? -1.322  -27.223 -25.023 1.00 74.00  ? 22  GLN A O   1 
ATOM   155  C  CB  . GLN A 1 22  ? 0.294   -25.394 -23.427 1.00 64.95  ? 22  GLN A CB  1 
ATOM   156  C  CG  . GLN A 1 22  ? -0.464  -25.088 -22.130 1.00 70.78  ? 22  GLN A CG  1 
ATOM   157  C  CD  . GLN A 1 22  ? -0.859  -23.634 -21.977 1.00 79.04  ? 22  GLN A CD  1 
ATOM   158  O  OE1 . GLN A 1 22  ? -0.938  -22.862 -22.941 1.00 75.70  ? 22  GLN A OE1 1 
ATOM   159  N  NE2 . GLN A 1 22  ? -1.130  -23.224 -20.751 1.00 63.61  ? 22  GLN A NE2 1 
ATOM   160  N  N   . LYS A 1 23  ? -0.797  -28.875 -23.557 1.00 75.70  ? 23  LYS A N   1 
ATOM   161  C  CA  . LYS A 1 23  ? -1.879  -29.807 -23.885 1.00 79.77  ? 23  LYS A CA  1 
ATOM   162  C  C   . LYS A 1 23  ? -3.274  -29.245 -23.584 1.00 86.87  ? 23  LYS A C   1 
ATOM   163  O  O   . LYS A 1 23  ? -4.188  -29.422 -24.394 1.00 88.20  ? 23  LYS A O   1 
ATOM   164  C  CB  . LYS A 1 23  ? -1.652  -31.169 -23.209 1.00 84.86  ? 23  LYS A CB  1 
ATOM   165  C  CG  . LYS A 1 23  ? -0.508  -31.960 -23.840 1.00 98.68  ? 23  LYS A CG  1 
ATOM   166  C  CD  . LYS A 1 23  ? -0.292  -33.300 -23.164 1.00 111.57 ? 23  LYS A CD  1 
ATOM   167  C  CE  . LYS A 1 23  ? 0.833   -34.066 -23.813 1.00 122.16 ? 23  LYS A CE  1 
ATOM   168  N  NZ  . LYS A 1 23  ? 1.033   -35.393 -23.177 1.00 133.68 ? 23  LYS A NZ  1 
ATOM   169  N  N   . GLU A 1 24  ? -3.423  -28.552 -22.439 1.00 84.09  ? 24  GLU A N   1 
ATOM   170  C  CA  . GLU A 1 24  ? -4.668  -27.904 -22.013 1.00 85.80  ? 24  GLU A CA  1 
ATOM   171  C  C   . GLU A 1 24  ? -4.398  -26.431 -21.693 1.00 88.44  ? 24  GLU A C   1 
ATOM   172  O  O   . GLU A 1 24  ? -3.359  -26.124 -21.104 1.00 86.04  ? 24  GLU A O   1 
ATOM   173  C  CB  . GLU A 1 24  ? -5.277  -28.622 -20.798 1.00 89.89  ? 24  GLU A CB  1 
ATOM   174  C  CG  . GLU A 1 24  ? -6.306  -29.675 -21.171 1.00 106.82 ? 24  GLU A CG  1 
ATOM   175  C  CD  . GLU A 1 24  ? -5.754  -31.061 -21.443 1.00 132.10 ? 24  GLU A CD  1 
ATOM   176  O  OE1 . GLU A 1 24  ? -5.617  -31.426 -22.633 1.00 124.67 ? 24  GLU A OE1 1 
ATOM   177  O  OE2 . GLU A 1 24  ? -5.468  -31.787 -20.464 1.00 129.68 ? 24  GLU A OE2 1 
ATOM   178  N  N   . SER A 1 25  ? -5.335  -25.530 -22.076 1.00 86.18  ? 25  SER A N   1 
ATOM   179  C  CA  . SER A 1 25  ? -5.261  -24.068 -21.893 1.00 84.50  ? 25  SER A CA  1 
ATOM   180  C  C   . SER A 1 25  ? -4.837  -23.608 -20.485 1.00 88.73  ? 25  SER A C   1 
ATOM   181  O  O   . SER A 1 25  ? -4.064  -22.650 -20.363 1.00 86.38  ? 25  SER A O   1 
ATOM   182  C  CB  . SER A 1 25  ? -6.581  -23.413 -22.286 1.00 89.66  ? 25  SER A CB  1 
ATOM   183  O  OG  . SER A 1 25  ? -7.634  -23.817 -21.425 1.00 101.70 ? 25  SER A OG  1 
ATOM   184  N  N   . ASN A 1 26  ? -5.344  -24.289 -19.435 1.00 87.21  ? 26  ASN A N   1 
ATOM   185  C  CA  . ASN A 1 26  ? -5.019  -23.998 -18.037 1.00 86.62  ? 26  ASN A CA  1 
ATOM   186  C  C   . ASN A 1 26  ? -3.799  -24.803 -17.540 1.00 88.58  ? 26  ASN A C   1 
ATOM   187  O  O   . ASN A 1 26  ? -3.165  -24.411 -16.559 1.00 87.76  ? 26  ASN A O   1 
ATOM   188  C  CB  . ASN A 1 26  ? -6.239  -24.249 -17.136 1.00 91.29  ? 26  ASN A CB  1 
ATOM   189  C  CG  . ASN A 1 26  ? -6.713  -25.688 -17.080 1.00 119.58 ? 26  ASN A CG  1 
ATOM   190  O  OD1 . ASN A 1 26  ? -6.751  -26.408 -18.089 1.00 114.96 ? 26  ASN A OD1 1 
ATOM   191  N  ND2 . ASN A 1 26  ? -7.098  -26.134 -15.892 1.00 113.32 ? 26  ASN A ND2 1 
ATOM   192  N  N   . GLY A 1 27  ? -3.499  -25.910 -18.224 1.00 83.95  ? 27  GLY A N   1 
ATOM   193  C  CA  . GLY A 1 27  ? -2.414  -26.830 -17.892 1.00 82.47  ? 27  GLY A CA  1 
ATOM   194  C  C   . GLY A 1 27  ? -1.005  -26.272 -17.996 1.00 80.31  ? 27  GLY A C   1 
ATOM   195  O  O   . GLY A 1 27  ? -0.804  -25.186 -18.551 1.00 77.73  ? 27  GLY A O   1 
ATOM   196  N  N   . PRO A 1 28  ? 0.007   -27.005 -17.466 1.00 74.47  ? 28  PRO A N   1 
ATOM   197  C  CA  . PRO A 1 28  ? 1.386   -26.493 -17.532 1.00 70.75  ? 28  PRO A CA  1 
ATOM   198  C  C   . PRO A 1 28  ? 2.022   -26.580 -18.918 1.00 69.63  ? 28  PRO A C   1 
ATOM   199  O  O   . PRO A 1 28  ? 1.664   -27.443 -19.720 1.00 70.19  ? 28  PRO A O   1 
ATOM   200  C  CB  . PRO A 1 28  ? 2.136   -27.345 -16.505 1.00 73.77  ? 28  PRO A CB  1 
ATOM   201  C  CG  . PRO A 1 28  ? 1.380   -28.615 -16.441 1.00 81.58  ? 28  PRO A CG  1 
ATOM   202  C  CD  . PRO A 1 28  ? -0.056  -28.308 -16.769 1.00 78.26  ? 28  PRO A CD  1 
ATOM   203  N  N   . VAL A 1 29  ? 2.978   -25.677 -19.181 1.00 61.83  ? 29  VAL A N   1 
ATOM   204  C  CA  . VAL A 1 29  ? 3.733   -25.611 -20.434 1.00 59.39  ? 29  VAL A CA  1 
ATOM   205  C  C   . VAL A 1 29  ? 5.026   -26.404 -20.266 1.00 62.38  ? 29  VAL A C   1 
ATOM   206  O  O   . VAL A 1 29  ? 5.836   -26.093 -19.388 1.00 61.20  ? 29  VAL A O   1 
ATOM   207  C  CB  . VAL A 1 29  ? 4.005   -24.154 -20.911 1.00 59.92  ? 29  VAL A CB  1 
ATOM   208  C  CG1 . VAL A 1 29  ? 4.764   -24.138 -22.239 1.00 58.38  ? 29  VAL A CG1 1 
ATOM   209  C  CG2 . VAL A 1 29  ? 2.709   -23.353 -21.026 1.00 59.68  ? 29  VAL A CG2 1 
ATOM   210  N  N   . LYS A 1 30  ? 5.199   -27.439 -21.097 1.00 59.98  ? 30  LYS A N   1 
ATOM   211  C  CA  . LYS A 1 30  ? 6.403   -28.264 -21.113 1.00 60.17  ? 30  LYS A CA  1 
ATOM   212  C  C   . LYS A 1 30  ? 7.393   -27.589 -22.069 1.00 61.72  ? 30  LYS A C   1 
ATOM   213  O  O   . LYS A 1 30  ? 7.095   -27.433 -23.251 1.00 60.36  ? 30  LYS A O   1 
ATOM   214  C  CB  . LYS A 1 30  ? 6.077   -29.697 -21.565 1.00 65.22  ? 30  LYS A CB  1 
ATOM   215  C  CG  . LYS A 1 30  ? 7.077   -30.727 -21.059 1.00 84.71  ? 30  LYS A CG  1 
ATOM   216  C  CD  . LYS A 1 30  ? 6.728   -32.140 -21.512 1.00 97.11  ? 30  LYS A CD  1 
ATOM   217  C  CE  . LYS A 1 30  ? 7.530   -32.585 -22.711 1.00 105.64 ? 30  LYS A CE  1 
ATOM   218  N  NZ  . LYS A 1 30  ? 8.916   -32.983 -22.344 1.00 112.95 ? 30  LYS A NZ  1 
ATOM   219  N  N   . VAL A 1 31  ? 8.528   -27.124 -21.534 1.00 58.41  ? 31  VAL A N   1 
ATOM   220  C  CA  . VAL A 1 31  ? 9.576   -26.441 -22.295 1.00 57.25  ? 31  VAL A CA  1 
ATOM   221  C  C   . VAL A 1 31  ? 10.847  -27.306 -22.302 1.00 61.27  ? 31  VAL A C   1 
ATOM   222  O  O   . VAL A 1 31  ? 11.374  -27.646 -21.247 1.00 61.71  ? 31  VAL A O   1 
ATOM   223  C  CB  . VAL A 1 31  ? 9.794   -24.945 -21.884 1.00 59.73  ? 31  VAL A CB  1 
ATOM   224  C  CG1 . VAL A 1 31  ? 9.388   -24.663 -20.450 1.00 60.02  ? 31  VAL A CG1 1 
ATOM   225  C  CG2 . VAL A 1 31  ? 11.200  -24.438 -22.179 1.00 58.59  ? 31  VAL A CG2 1 
ATOM   226  N  N   . TRP A 1 32  ? 11.291  -27.712 -23.506 1.00 57.74  ? 32  TRP A N   1 
ATOM   227  C  CA  . TRP A 1 32  ? 12.453  -28.585 -23.673 1.00 57.95  ? 32  TRP A CA  1 
ATOM   228  C  C   . TRP A 1 32  ? 13.277  -28.264 -24.910 1.00 59.68  ? 32  TRP A C   1 
ATOM   229  O  O   . TRP A 1 32  ? 12.759  -27.725 -25.878 1.00 57.58  ? 32  TRP A O   1 
ATOM   230  C  CB  . TRP A 1 32  ? 12.037  -30.073 -23.644 1.00 58.94  ? 32  TRP A CB  1 
ATOM   231  C  CG  . TRP A 1 32  ? 11.422  -30.590 -24.915 1.00 60.30  ? 32  TRP A CG  1 
ATOM   232  C  CD1 . TRP A 1 32  ? 12.030  -31.360 -25.864 1.00 64.67  ? 32  TRP A CD1 1 
ATOM   233  C  CD2 . TRP A 1 32  ? 10.070  -30.401 -25.356 1.00 59.67  ? 32  TRP A CD2 1 
ATOM   234  N  NE1 . TRP A 1 32  ? 11.145  -31.651 -26.877 1.00 64.68  ? 32  TRP A NE1 1 
ATOM   235  C  CE2 . TRP A 1 32  ? 9.934   -31.073 -26.592 1.00 65.04  ? 32  TRP A CE2 1 
ATOM   236  C  CE3 . TRP A 1 32  ? 8.959   -29.714 -24.834 1.00 59.68  ? 32  TRP A CE3 1 
ATOM   237  C  CZ2 . TRP A 1 32  ? 8.729   -31.091 -27.308 1.00 64.73  ? 32  TRP A CZ2 1 
ATOM   238  C  CZ3 . TRP A 1 32  ? 7.766   -29.738 -25.538 1.00 61.55  ? 32  TRP A CZ3 1 
ATOM   239  C  CH2 . TRP A 1 32  ? 7.658   -30.417 -26.761 1.00 63.68  ? 32  TRP A CH2 1 
ATOM   240  N  N   . GLY A 1 33  ? 14.553  -28.617 -24.863 1.00 56.65  ? 33  GLY A N   1 
ATOM   241  C  CA  . GLY A 1 33  ? 15.474  -28.397 -25.968 1.00 55.92  ? 33  GLY A CA  1 
ATOM   242  C  C   . GLY A 1 33  ? 16.916  -28.390 -25.527 1.00 59.53  ? 33  GLY A C   1 
ATOM   243  O  O   . GLY A 1 33  ? 17.255  -28.963 -24.488 1.00 59.29  ? 33  GLY A O   1 
ATOM   244  N  N   . SER A 1 34  ? 17.774  -27.736 -26.323 1.00 56.09  ? 34  SER A N   1 
ATOM   245  C  CA  . SER A 1 34  ? 19.205  -27.663 -26.054 1.00 57.31  ? 34  SER A CA  1 
ATOM   246  C  C   . SER A 1 34  ? 19.804  -26.344 -26.516 1.00 59.51  ? 34  SER A C   1 
ATOM   247  O  O   . SER A 1 34  ? 19.401  -25.810 -27.551 1.00 57.99  ? 34  SER A O   1 
ATOM   248  C  CB  . SER A 1 34  ? 19.927  -28.830 -26.725 1.00 64.98  ? 34  SER A CB  1 
ATOM   249  O  OG  . SER A 1 34  ? 21.287  -28.908 -26.330 1.00 80.09  ? 34  SER A OG  1 
ATOM   250  N  N   . ILE A 1 35  ? 20.784  -25.830 -25.747 1.00 55.64  ? 35  ILE A N   1 
ATOM   251  C  CA  . ILE A 1 35  ? 21.522  -24.602 -26.062 1.00 53.90  ? 35  ILE A CA  1 
ATOM   252  C  C   . ILE A 1 35  ? 23.033  -24.899 -26.027 1.00 60.52  ? 35  ILE A C   1 
ATOM   253  O  O   . ILE A 1 35  ? 23.499  -25.509 -25.067 1.00 62.45  ? 35  ILE A O   1 
ATOM   254  C  CB  . ILE A 1 35  ? 21.147  -23.407 -25.136 1.00 54.49  ? 35  ILE A CB  1 
ATOM   255  C  CG1 . ILE A 1 35  ? 19.629  -23.338 -24.839 1.00 53.63  ? 35  ILE A CG1 1 
ATOM   256  C  CG2 . ILE A 1 35  ? 21.666  -22.091 -25.732 1.00 53.47  ? 35  ILE A CG2 1 
ATOM   257  C  CD1 . ILE A 1 35  ? 19.218  -22.499 -23.625 1.00 57.96  ? 35  ILE A CD1 1 
ATOM   258  N  N   . LYS A 1 36  ? 23.790  -24.477 -27.069 1.00 57.05  ? 36  LYS A N   1 
ATOM   259  C  CA  . LYS A 1 36  ? 25.251  -24.656 -27.138 1.00 59.12  ? 36  LYS A CA  1 
ATOM   260  C  C   . LYS A 1 36  ? 26.005  -23.307 -27.192 1.00 62.15  ? 36  LYS A C   1 
ATOM   261  O  O   . LYS A 1 36  ? 25.370  -22.260 -27.317 1.00 59.53  ? 36  LYS A O   1 
ATOM   262  C  CB  . LYS A 1 36  ? 25.672  -25.612 -28.281 1.00 63.44  ? 36  LYS A CB  1 
ATOM   263  C  CG  . LYS A 1 36  ? 25.229  -25.211 -29.690 1.00 67.96  ? 36  LYS A CG  1 
ATOM   264  C  CD  . LYS A 1 36  ? 25.687  -26.256 -30.706 1.00 78.13  ? 36  LYS A CD  1 
ATOM   265  C  CE  . LYS A 1 36  ? 25.461  -25.836 -32.137 1.00 84.99  ? 36  LYS A CE  1 
ATOM   266  N  NZ  . LYS A 1 36  ? 25.902  -26.880 -33.099 1.00 95.93  ? 36  LYS A NZ  1 
ATOM   267  N  N   . GLY A 1 37  ? 27.336  -23.350 -27.067 1.00 60.21  ? 37  GLY A N   1 
ATOM   268  C  CA  . GLY A 1 37  ? 28.196  -22.165 -27.071 1.00 59.68  ? 37  GLY A CA  1 
ATOM   269  C  C   . GLY A 1 37  ? 28.163  -21.374 -25.774 1.00 61.28  ? 37  GLY A C   1 
ATOM   270  O  O   . GLY A 1 37  ? 28.537  -20.199 -25.744 1.00 59.58  ? 37  GLY A O   1 
ATOM   271  N  N   . LEU A 1 38  ? 27.724  -22.025 -24.691 1.00 58.44  ? 38  LEU A N   1 
ATOM   272  C  CA  . LEU A 1 38  ? 27.571  -21.455 -23.352 1.00 58.06  ? 38  LEU A CA  1 
ATOM   273  C  C   . LEU A 1 38  ? 28.772  -21.735 -22.477 1.00 64.54  ? 38  LEU A C   1 
ATOM   274  O  O   . LEU A 1 38  ? 29.362  -22.807 -22.573 1.00 65.61  ? 38  LEU A O   1 
ATOM   275  C  CB  . LEU A 1 38  ? 26.339  -22.110 -22.688 1.00 57.06  ? 38  LEU A CB  1 
ATOM   276  C  CG  . LEU A 1 38  ? 25.008  -21.345 -22.517 1.00 58.75  ? 38  LEU A CG  1 
ATOM   277  C  CD1 . LEU A 1 38  ? 24.921  -20.093 -23.321 1.00 56.60  ? 38  LEU A CD1 1 
ATOM   278  C  CD2 . LEU A 1 38  ? 23.832  -22.249 -22.723 1.00 60.22  ? 38  LEU A CD2 1 
ATOM   279  N  N   . THR A 1 39  ? 29.097  -20.806 -21.573 1.00 61.82  ? 39  THR A N   1 
ATOM   280  C  CA  . THR A 1 39  ? 30.157  -21.032 -20.587 1.00 64.39  ? 39  THR A CA  1 
ATOM   281  C  C   . THR A 1 39  ? 29.547  -22.003 -19.561 1.00 66.79  ? 39  THR A C   1 
ATOM   282  O  O   . THR A 1 39  ? 28.334  -21.963 -19.330 1.00 62.38  ? 39  THR A O   1 
ATOM   283  C  CB  . THR A 1 39  ? 30.599  -19.716 -19.906 1.00 74.51  ? 39  THR A CB  1 
ATOM   284  O  OG1 . THR A 1 39  ? 29.567  -19.259 -19.032 1.00 73.66  ? 39  THR A OG1 1 
ATOM   285  C  CG2 . THR A 1 39  ? 30.937  -18.621 -20.901 1.00 71.52  ? 39  THR A CG2 1 
ATOM   286  N  N   . GLU A 1 40  ? 30.373  -22.883 -18.976 1.00 67.22  ? 40  GLU A N   1 
ATOM   287  C  CA  . GLU A 1 40  ? 29.929  -23.859 -17.975 1.00 67.68  ? 40  GLU A CA  1 
ATOM   288  C  C   . GLU A 1 40  ? 29.270  -23.150 -16.790 1.00 69.12  ? 40  GLU A C   1 
ATOM   289  O  O   . GLU A 1 40  ? 29.726  -22.082 -16.374 1.00 68.10  ? 40  GLU A O   1 
ATOM   290  C  CB  . GLU A 1 40  ? 31.119  -24.701 -17.491 1.00 72.49  ? 40  GLU A CB  1 
ATOM   291  C  CG  . GLU A 1 40  ? 30.720  -26.012 -16.836 1.00 80.99  ? 40  GLU A CG  1 
ATOM   292  C  CD  . GLU A 1 40  ? 31.855  -26.868 -16.304 1.00 101.38 ? 40  GLU A CD  1 
ATOM   293  O  OE1 . GLU A 1 40  ? 33.037  -26.542 -16.561 1.00 86.48  ? 40  GLU A OE1 1 
ATOM   294  O  OE2 . GLU A 1 40  ? 31.555  -27.881 -15.632 1.00 99.32  ? 40  GLU A OE2 1 
ATOM   295  N  N   . GLY A 1 41  ? 28.178  -23.729 -16.305 1.00 64.88  ? 41  GLY A N   1 
ATOM   296  C  CA  . GLY A 1 41  ? 27.429  -23.196 -15.175 1.00 63.33  ? 41  GLY A CA  1 
ATOM   297  C  C   . GLY A 1 41  ? 26.021  -22.753 -15.512 1.00 63.14  ? 41  GLY A C   1 
ATOM   298  O  O   . GLY A 1 41  ? 25.480  -23.103 -16.566 1.00 61.58  ? 41  GLY A O   1 
ATOM   299  N  N   . LEU A 1 42  ? 25.423  -21.967 -14.606 1.00 58.40  ? 42  LEU A N   1 
ATOM   300  C  CA  . LEU A 1 42  ? 24.046  -21.472 -14.713 1.00 56.38  ? 42  LEU A CA  1 
ATOM   301  C  C   . LEU A 1 42  ? 23.929  -20.208 -15.569 1.00 57.16  ? 42  LEU A C   1 
ATOM   302  O  O   . LEU A 1 42  ? 24.835  -19.370 -15.574 1.00 56.79  ? 42  LEU A O   1 
ATOM   303  C  CB  . LEU A 1 42  ? 23.461  -21.244 -13.295 1.00 56.85  ? 42  LEU A CB  1 
ATOM   304  C  CG  . LEU A 1 42  ? 22.813  -22.440 -12.568 1.00 62.32  ? 42  LEU A CG  1 
ATOM   305  C  CD1 . LEU A 1 42  ? 23.834  -23.515 -12.210 1.00 65.76  ? 42  LEU A CD1 1 
ATOM   306  C  CD2 . LEU A 1 42  ? 22.191  -21.987 -11.262 1.00 65.49  ? 42  LEU A CD2 1 
ATOM   307  N  N   . HIS A 1 43  ? 22.809  -20.078 -16.299 1.00 52.20  ? 43  HIS A N   1 
ATOM   308  C  CA  . HIS A 1 43  ? 22.533  -18.930 -17.162 1.00 51.30  ? 43  HIS A CA  1 
ATOM   309  C  C   . HIS A 1 43  ? 21.075  -18.534 -17.064 1.00 52.11  ? 43  HIS A C   1 
ATOM   310  O  O   . HIS A 1 43  ? 20.197  -19.391 -17.244 1.00 50.20  ? 43  HIS A O   1 
ATOM   311  C  CB  . HIS A 1 43  ? 22.867  -19.252 -18.636 1.00 52.33  ? 43  HIS A CB  1 
ATOM   312  C  CG  . HIS A 1 43  ? 24.338  -19.385 -18.897 1.00 57.59  ? 43  HIS A CG  1 
ATOM   313  N  ND1 . HIS A 1 43  ? 25.098  -18.302 -19.294 1.00 59.81  ? 43  HIS A ND1 1 
ATOM   314  C  CD2 . HIS A 1 43  ? 25.138  -20.468 -18.796 1.00 61.04  ? 43  HIS A CD2 1 
ATOM   315  C  CE1 . HIS A 1 43  ? 26.332  -18.755 -19.416 1.00 61.37  ? 43  HIS A CE1 1 
ATOM   316  N  NE2 . HIS A 1 43  ? 26.406  -20.050 -19.115 1.00 62.76  ? 43  HIS A NE2 1 
ATOM   317  N  N   . GLY A 1 44  ? 20.825  -17.245 -16.822 1.00 48.21  ? 44  GLY A N   1 
ATOM   318  C  CA  . GLY A 1 44  ? 19.469  -16.702 -16.759 1.00 47.06  ? 44  GLY A CA  1 
ATOM   319  C  C   . GLY A 1 44  ? 18.683  -17.068 -18.006 1.00 49.73  ? 44  GLY A C   1 
ATOM   320  O  O   . GLY A 1 44  ? 19.228  -17.030 -19.112 1.00 47.87  ? 44  GLY A O   1 
ATOM   321  N  N   . PHE A 1 45  ? 17.430  -17.518 -17.824 1.00 46.65  ? 45  PHE A N   1 
ATOM   322  C  CA  . PHE A 1 45  ? 16.564  -17.975 -18.909 1.00 45.88  ? 45  PHE A CA  1 
ATOM   323  C  C   . PHE A 1 45  ? 15.198  -17.276 -18.739 1.00 50.86  ? 45  PHE A C   1 
ATOM   324  O  O   . PHE A 1 45  ? 14.393  -17.653 -17.873 1.00 50.09  ? 45  PHE A O   1 
ATOM   325  C  CB  . PHE A 1 45  ? 16.479  -19.508 -18.829 1.00 48.56  ? 45  PHE A CB  1 
ATOM   326  C  CG  . PHE A 1 45  ? 15.822  -20.238 -19.974 1.00 49.46  ? 45  PHE A CG  1 
ATOM   327  C  CD1 . PHE A 1 45  ? 16.404  -20.252 -21.238 1.00 52.18  ? 45  PHE A CD1 1 
ATOM   328  C  CD2 . PHE A 1 45  ? 14.692  -21.016 -19.762 1.00 50.90  ? 45  PHE A CD2 1 
ATOM   329  C  CE1 . PHE A 1 45  ? 15.832  -20.982 -22.279 1.00 52.39  ? 45  PHE A CE1 1 
ATOM   330  C  CE2 . PHE A 1 45  ? 14.106  -21.730 -20.812 1.00 53.24  ? 45  PHE A CE2 1 
ATOM   331  C  CZ  . PHE A 1 45  ? 14.685  -21.716 -22.058 1.00 51.22  ? 45  PHE A CZ  1 
ATOM   332  N  N   . HIS A 1 46  ? 14.993  -16.181 -19.503 1.00 46.13  ? 46  HIS A N   1 
ATOM   333  C  CA  . HIS A 1 46  ? 13.828  -15.322 -19.332 1.00 45.49  ? 46  HIS A CA  1 
ATOM   334  C  C   . HIS A 1 46  ? 13.028  -15.008 -20.597 1.00 46.06  ? 46  HIS A C   1 
ATOM   335  O  O   . HIS A 1 46  ? 13.602  -14.828 -21.665 1.00 44.51  ? 46  HIS A O   1 
ATOM   336  C  CB  . HIS A 1 46  ? 14.252  -13.983 -18.682 1.00 46.88  ? 46  HIS A CB  1 
ATOM   337  C  CG  . HIS A 1 46  ? 15.076  -14.100 -17.431 1.00 51.84  ? 46  HIS A CG  1 
ATOM   338  N  ND1 . HIS A 1 46  ? 16.195  -13.313 -17.238 1.00 54.35  ? 46  HIS A ND1 1 
ATOM   339  C  CD2 . HIS A 1 46  ? 14.904  -14.886 -16.341 1.00 54.02  ? 46  HIS A CD2 1 
ATOM   340  C  CE1 . HIS A 1 46  ? 16.671  -13.648 -16.049 1.00 54.51  ? 46  HIS A CE1 1 
ATOM   341  N  NE2 . HIS A 1 46  ? 15.943  -14.607 -15.485 1.00 54.80  ? 46  HIS A NE2 1 
ATOM   342  N  N   . VAL A 1 47  ? 11.708  -14.846 -20.434 1.00 43.17  ? 47  VAL A N   1 
ATOM   343  C  CA  . VAL A 1 47  ? 10.807  -14.403 -21.501 1.00 40.77  ? 47  VAL A CA  1 
ATOM   344  C  C   . VAL A 1 47  ? 10.722  -12.886 -21.324 1.00 43.60  ? 47  VAL A C   1 
ATOM   345  O  O   . VAL A 1 47  ? 10.393  -12.402 -20.235 1.00 43.47  ? 47  VAL A O   1 
ATOM   346  C  CB  . VAL A 1 47  ? 9.407   -15.083 -21.502 1.00 43.88  ? 47  VAL A CB  1 
ATOM   347  C  CG1 . VAL A 1 47  ? 8.546   -14.577 -22.664 1.00 43.51  ? 47  VAL A CG1 1 
ATOM   348  C  CG2 . VAL A 1 47  ? 9.527   -16.603 -21.552 1.00 43.68  ? 47  VAL A CG2 1 
ATOM   349  N  N   . HIS A 1 48  ? 11.111  -12.153 -22.374 1.00 40.64  ? 48  HIS A N   1 
ATOM   350  C  CA  . HIS A 1 48  ? 11.112  -10.694 -22.449 1.00 40.43  ? 48  HIS A CA  1 
ATOM   351  C  C   . HIS A 1 48  ? 9.863   -10.255 -23.194 1.00 43.53  ? 48  HIS A C   1 
ATOM   352  O  O   . HIS A 1 48  ? 9.289   -11.050 -23.929 1.00 43.09  ? 48  HIS A O   1 
ATOM   353  C  CB  . HIS A 1 48  ? 12.432  -10.169 -23.053 1.00 40.80  ? 48  HIS A CB  1 
ATOM   354  C  CG  . HIS A 1 48  ? 13.593  -10.294 -22.102 1.00 45.22  ? 48  HIS A CG  1 
ATOM   355  N  ND1 . HIS A 1 48  ? 14.173  -9.178  -21.517 1.00 47.98  ? 48  HIS A ND1 1 
ATOM   356  C  CD2 . HIS A 1 48  ? 14.197  -11.404 -21.610 1.00 46.77  ? 48  HIS A CD2 1 
ATOM   357  C  CE1 . HIS A 1 48  ? 15.142  -9.639  -20.743 1.00 48.18  ? 48  HIS A CE1 1 
ATOM   358  N  NE2 . HIS A 1 48  ? 15.202  -10.971 -20.772 1.00 47.89  ? 48  HIS A NE2 1 
ATOM   359  N  N   . GLU A 1 49  ? 9.385   -9.040  -22.919 1.00 42.68  ? 49  GLU A N   1 
ATOM   360  C  CA  . GLU A 1 49  ? 8.098   -8.519  -23.370 1.00 43.89  ? 49  GLU A CA  1 
ATOM   361  C  C   . GLU A 1 49  ? 7.881   -8.469  -24.886 1.00 47.63  ? 49  GLU A C   1 
ATOM   362  O  O   . GLU A 1 49  ? 6.791   -8.839  -25.345 1.00 45.87  ? 49  GLU A O   1 
ATOM   363  C  CB  . GLU A 1 49  ? 7.842   -7.132  -22.755 1.00 46.87  ? 49  GLU A CB  1 
ATOM   364  C  CG  . GLU A 1 49  ? 6.408   -6.633  -22.913 1.00 58.74  ? 49  GLU A CG  1 
ATOM   365  C  CD  . GLU A 1 49  ? 6.098   -5.283  -22.290 1.00 76.13  ? 49  GLU A CD  1 
ATOM   366  O  OE1 . GLU A 1 49  ? 6.936   -4.763  -21.515 1.00 59.76  ? 49  GLU A OE1 1 
ATOM   367  O  OE2 . GLU A 1 49  ? 5.007   -4.744  -22.582 1.00 68.71  ? 49  GLU A OE2 1 
ATOM   368  N  N   . PHE A 1 50  ? 8.870   -7.984  -25.653 1.00 45.91  ? 50  PHE A N   1 
ATOM   369  C  CA  . PHE A 1 50  ? 8.660   -7.796  -27.085 1.00 46.19  ? 50  PHE A CA  1 
ATOM   370  C  C   . PHE A 1 50  ? 9.337   -8.792  -27.984 1.00 49.03  ? 50  PHE A C   1 
ATOM   371  O  O   . PHE A 1 50  ? 10.494  -9.131  -27.758 1.00 48.48  ? 50  PHE A O   1 
ATOM   372  C  CB  . PHE A 1 50  ? 9.065   -6.368  -27.499 1.00 49.53  ? 50  PHE A CB  1 
ATOM   373  C  CG  . PHE A 1 50  ? 8.460   -5.295  -26.622 1.00 53.05  ? 50  PHE A CG  1 
ATOM   374  C  CD1 . PHE A 1 50  ? 7.088   -5.060  -26.627 1.00 57.28  ? 50  PHE A CD1 1 
ATOM   375  C  CD2 . PHE A 1 50  ? 9.256   -4.540  -25.770 1.00 55.84  ? 50  PHE A CD2 1 
ATOM   376  C  CE1 . PHE A 1 50  ? 6.524   -4.104  -25.772 1.00 59.57  ? 50  PHE A CE1 1 
ATOM   377  C  CE2 . PHE A 1 50  ? 8.695   -3.563  -24.945 1.00 59.98  ? 50  PHE A CE2 1 
ATOM   378  C  CZ  . PHE A 1 50  ? 7.333   -3.349  -24.955 1.00 58.69  ? 50  PHE A CZ  1 
ATOM   379  N  N   . GLY A 1 51  ? 8.631   -9.180  -29.050 1.00 45.30  ? 51  GLY A N   1 
ATOM   380  C  CA  . GLY A 1 51  ? 9.153   -10.039 -30.105 1.00 44.57  ? 51  GLY A CA  1 
ATOM   381  C  C   . GLY A 1 51  ? 9.832   -9.186  -31.163 1.00 48.51  ? 51  GLY A C   1 
ATOM   382  O  O   . GLY A 1 51  ? 9.637   -9.393  -32.363 1.00 46.24  ? 51  GLY A O   1 
ATOM   383  N  N   . ASP A 1 52  ? 10.614  -8.186  -30.706 1.00 46.07  ? 52  ASP A N   1 
ATOM   384  C  CA  . ASP A 1 52  ? 11.294  -7.208  -31.551 1.00 46.54  ? 52  ASP A CA  1 
ATOM   385  C  C   . ASP A 1 52  ? 12.808  -7.466  -31.559 1.00 50.29  ? 52  ASP A C   1 
ATOM   386  O  O   . ASP A 1 52  ? 13.472  -7.291  -30.541 1.00 49.12  ? 52  ASP A O   1 
ATOM   387  C  CB  . ASP A 1 52  ? 10.965  -5.785  -31.027 1.00 48.72  ? 52  ASP A CB  1 
ATOM   388  C  CG  . ASP A 1 52  ? 11.468  -4.626  -31.865 1.00 55.24  ? 52  ASP A CG  1 
ATOM   389  O  OD1 . ASP A 1 52  ? 12.427  -4.818  -32.630 1.00 55.36  ? 52  ASP A OD1 1 
ATOM   390  O  OD2 . ASP A 1 52  ? 10.913  -3.522  -31.740 1.00 61.67  ? 52  ASP A OD2 1 
ATOM   391  N  N   . ASN A 1 53  ? 13.348  -7.873  -32.714 1.00 48.06  ? 53  ASN A N   1 
ATOM   392  C  CA  . ASN A 1 53  ? 14.776  -8.130  -32.841 1.00 48.46  ? 53  ASN A CA  1 
ATOM   393  C  C   . ASN A 1 53  ? 15.452  -7.109  -33.783 1.00 51.52  ? 53  ASN A C   1 
ATOM   394  O  O   . ASN A 1 53  ? 16.503  -7.409  -34.331 1.00 52.16  ? 53  ASN A O   1 
ATOM   395  C  CB  . ASN A 1 53  ? 15.013  -9.586  -33.287 1.00 51.36  ? 53  ASN A CB  1 
ATOM   396  C  CG  . ASN A 1 53  ? 16.439  -10.076 -33.093 1.00 70.65  ? 53  ASN A CG  1 
ATOM   397  O  OD1 . ASN A 1 53  ? 16.954  -10.168 -31.979 1.00 61.85  ? 53  ASN A OD1 1 
ATOM   398  N  ND2 . ASN A 1 53  ? 17.116  -10.401 -34.178 1.00 60.42  ? 53  ASN A ND2 1 
ATOM   399  N  N   . THR A 1 54  ? 14.876  -5.893  -33.944 1.00 47.76  ? 54  THR A N   1 
ATOM   400  C  CA  . THR A 1 54  ? 15.425  -4.865  -34.858 1.00 49.68  ? 54  THR A CA  1 
ATOM   401  C  C   . THR A 1 54  ? 16.821  -4.353  -34.475 1.00 56.83  ? 54  THR A C   1 
ATOM   402  O  O   . THR A 1 54  ? 17.577  -3.952  -35.355 1.00 58.81  ? 54  THR A O   1 
ATOM   403  C  CB  . THR A 1 54  ? 14.463  -3.687  -35.053 1.00 58.15  ? 54  THR A CB  1 
ATOM   404  O  OG1 . THR A 1 54  ? 14.156  -3.102  -33.791 1.00 59.79  ? 54  THR A OG1 1 
ATOM   405  C  CG2 . THR A 1 54  ? 13.201  -4.075  -35.797 1.00 55.50  ? 54  THR A CG2 1 
ATOM   406  N  N   . ALA A 1 55  ? 17.147  -4.351  -33.176 1.00 54.43  ? 55  ALA A N   1 
ATOM   407  C  CA  . ALA A 1 55  ? 18.444  -3.923  -32.661 1.00 56.06  ? 55  ALA A CA  1 
ATOM   408  C  C   . ALA A 1 55  ? 19.040  -5.060  -31.816 1.00 59.96  ? 55  ALA A C   1 
ATOM   409  O  O   . ALA A 1 55  ? 19.577  -4.816  -30.738 1.00 61.02  ? 55  ALA A O   1 
ATOM   410  C  CB  . ALA A 1 55  ? 18.276  -2.655  -31.827 1.00 57.93  ? 55  ALA A CB  1 
ATOM   411  N  N   . GLY A 1 56  ? 18.931  -6.295  -32.317 1.00 54.76  ? 56  GLY A N   1 
ATOM   412  C  CA  . GLY A 1 56  ? 19.391  -7.482  -31.606 1.00 53.64  ? 56  GLY A CA  1 
ATOM   413  C  C   . GLY A 1 56  ? 18.508  -7.806  -30.406 1.00 55.83  ? 56  GLY A C   1 
ATOM   414  O  O   . GLY A 1 56  ? 17.324  -7.454  -30.389 1.00 54.77  ? 56  GLY A O   1 
ATOM   415  N  N   . CYS A 1 57  ? 19.080  -8.461  -29.385 1.00 52.11  ? 57  CYS A N   1 
ATOM   416  C  CA  . CYS A 1 57  ? 18.364  -8.877  -28.171 1.00 52.25  ? 57  CYS A CA  1 
ATOM   417  C  C   . CYS A 1 57  ? 17.927  -7.700  -27.258 1.00 54.91  ? 57  CYS A C   1 
ATOM   418  O  O   . CYS A 1 57  ? 16.967  -7.862  -26.496 1.00 52.14  ? 57  CYS A O   1 
ATOM   419  C  CB  . CYS A 1 57  ? 19.164  -9.934  -27.408 1.00 53.06  ? 57  CYS A CB  1 
ATOM   420  S  SG  . CYS A 1 57  ? 19.484  -11.445 -28.372 1.00 57.19  ? 57  CYS A SG  1 
ATOM   421  N  N   . THR A 1 58  ? 18.563  -6.511  -27.400 1.00 52.80  ? 58  THR A N   1 
ATOM   422  C  CA  . THR A 1 58  ? 18.220  -5.294  -26.639 1.00 53.84  ? 58  THR A CA  1 
ATOM   423  C  C   . THR A 1 58  ? 16.774  -4.812  -26.935 1.00 56.21  ? 58  THR A C   1 
ATOM   424  O  O   . THR A 1 58  ? 16.082  -4.379  -26.015 1.00 55.83  ? 58  THR A O   1 
ATOM   425  C  CB  . THR A 1 58  ? 19.268  -4.184  -26.894 1.00 67.54  ? 58  THR A CB  1 
ATOM   426  O  OG1 . THR A 1 58  ? 20.573  -4.685  -26.591 1.00 71.15  ? 58  THR A OG1 1 
ATOM   427  C  CG2 . THR A 1 58  ? 19.016  -2.922  -26.063 1.00 67.28  ? 58  THR A CG2 1 
ATOM   428  N  N   . SER A 1 59  ? 16.331  -4.890  -28.211 1.00 51.66  ? 59  SER A N   1 
ATOM   429  C  CA  . SER A 1 59  ? 14.997  -4.442  -28.626 1.00 50.29  ? 59  SER A CA  1 
ATOM   430  C  C   . SER A 1 59  ? 13.847  -5.305  -28.054 1.00 51.76  ? 59  SER A C   1 
ATOM   431  O  O   . SER A 1 59  ? 12.691  -4.885  -28.122 1.00 52.33  ? 59  SER A O   1 
ATOM   432  C  CB  . SER A 1 59  ? 14.904  -4.295  -30.147 1.00 52.21  ? 59  SER A CB  1 
ATOM   433  O  OG  . SER A 1 59  ? 15.466  -5.381  -30.865 1.00 56.37  ? 59  SER A OG  1 
ATOM   434  N  N   . ALA A 1 60  ? 14.165  -6.457  -27.422 1.00 46.48  ? 60  ALA A N   1 
ATOM   435  C  CA  . ALA A 1 60  ? 13.169  -7.323  -26.780 1.00 45.64  ? 60  ALA A CA  1 
ATOM   436  C  C   . ALA A 1 60  ? 12.597  -6.674  -25.500 1.00 51.19  ? 60  ALA A C   1 
ATOM   437  O  O   . ALA A 1 60  ? 11.543  -7.081  -25.015 1.00 51.02  ? 60  ALA A O   1 
ATOM   438  C  CB  . ALA A 1 60  ? 13.772  -8.680  -26.467 1.00 45.63  ? 60  ALA A CB  1 
ATOM   439  N  N   . GLY A 1 61  ? 13.280  -5.644  -25.007 1.00 48.14  ? 61  GLY A N   1 
ATOM   440  C  CA  . GLY A 1 61  ? 12.856  -4.867  -23.854 1.00 49.06  ? 61  GLY A CA  1 
ATOM   441  C  C   . GLY A 1 61  ? 12.998  -5.571  -22.522 1.00 50.98  ? 61  GLY A C   1 
ATOM   442  O  O   . GLY A 1 61  ? 13.850  -6.455  -22.373 1.00 48.74  ? 61  GLY A O   1 
ATOM   443  N  N   . PRO A 1 62  ? 12.158  -5.194  -21.529 1.00 48.91  ? 62  PRO A N   1 
ATOM   444  C  CA  . PRO A 1 62  ? 12.282  -5.805  -20.195 1.00 48.20  ? 62  PRO A CA  1 
ATOM   445  C  C   . PRO A 1 62  ? 11.659  -7.192  -20.108 1.00 50.30  ? 62  PRO A C   1 
ATOM   446  O  O   . PRO A 1 62  ? 11.115  -7.684  -21.085 1.00 48.63  ? 62  PRO A O   1 
ATOM   447  C  CB  . PRO A 1 62  ? 11.573  -4.797  -19.284 1.00 51.21  ? 62  PRO A CB  1 
ATOM   448  C  CG  . PRO A 1 62  ? 10.556  -4.152  -20.152 1.00 55.91  ? 62  PRO A CG  1 
ATOM   449  C  CD  . PRO A 1 62  ? 11.098  -4.162  -21.559 1.00 51.51  ? 62  PRO A CD  1 
ATOM   450  N  N   . HIS A 1 63  ? 11.717  -7.809  -18.924 1.00 48.29  ? 63  HIS A N   1 
ATOM   451  C  CA  . HIS A 1 63  ? 11.108  -9.115  -18.663 1.00 47.59  ? 63  HIS A CA  1 
ATOM   452  C  C   . HIS A 1 63  ? 9.607   -9.050  -18.904 1.00 50.13  ? 63  HIS A C   1 
ATOM   453  O  O   . HIS A 1 63  ? 9.004   -7.984  -18.738 1.00 50.50  ? 63  HIS A O   1 
ATOM   454  C  CB  . HIS A 1 63  ? 11.336  -9.511  -17.196 1.00 49.08  ? 63  HIS A CB  1 
ATOM   455  C  CG  . HIS A 1 63  ? 12.720  -9.996  -16.886 1.00 52.82  ? 63  HIS A CG  1 
ATOM   456  N  ND1 . HIS A 1 63  ? 12.967  -10.785 -15.780 1.00 55.31  ? 63  HIS A ND1 1 
ATOM   457  C  CD2 . HIS A 1 63  ? 13.886  -9.780  -17.535 1.00 54.32  ? 63  HIS A CD2 1 
ATOM   458  C  CE1 . HIS A 1 63  ? 14.265  -11.040 -15.805 1.00 54.71  ? 63  HIS A CE1 1 
ATOM   459  N  NE2 . HIS A 1 63  ? 14.859  -10.453 -16.840 1.00 54.56  ? 63  HIS A NE2 1 
ATOM   460  N  N   . PHE A 1 64  ? 8.997   -10.180 -19.299 1.00 45.22  ? 64  PHE A N   1 
ATOM   461  C  CA  . PHE A 1 64  ? 7.550   -10.217 -19.476 1.00 43.65  ? 64  PHE A CA  1 
ATOM   462  C  C   . PHE A 1 64  ? 6.951   -10.323 -18.077 1.00 48.82  ? 64  PHE A C   1 
ATOM   463  O  O   . PHE A 1 64  ? 7.065   -11.352 -17.411 1.00 49.10  ? 64  PHE A O   1 
ATOM   464  C  CB  . PHE A 1 64  ? 7.089   -11.343 -20.419 1.00 43.48  ? 64  PHE A CB  1 
ATOM   465  C  CG  . PHE A 1 64  ? 5.590   -11.442 -20.596 1.00 43.93  ? 64  PHE A CG  1 
ATOM   466  C  CD1 . PHE A 1 64  ? 4.824   -10.307 -20.838 1.00 47.42  ? 64  PHE A CD1 1 
ATOM   467  C  CD2 . PHE A 1 64  ? 4.949   -12.673 -20.547 1.00 45.71  ? 64  PHE A CD2 1 
ATOM   468  C  CE1 . PHE A 1 64  ? 3.435   -10.403 -21.012 1.00 49.65  ? 64  PHE A CE1 1 
ATOM   469  C  CE2 . PHE A 1 64  ? 3.562   -12.771 -20.728 1.00 49.13  ? 64  PHE A CE2 1 
ATOM   470  C  CZ  . PHE A 1 64  ? 2.814   -11.636 -20.965 1.00 48.22  ? 64  PHE A CZ  1 
ATOM   471  N  N   . ASN A 1 65  ? 6.412   -9.203  -17.610 1.00 46.67  ? 65  ASN A N   1 
ATOM   472  C  CA  . ASN A 1 65  ? 5.884   -9.044  -16.262 1.00 47.84  ? 65  ASN A CA  1 
ATOM   473  C  C   . ASN A 1 65  ? 4.560   -8.256  -16.326 1.00 53.86  ? 65  ASN A C   1 
ATOM   474  O  O   . ASN A 1 65  ? 4.539   -7.073  -15.958 1.00 55.24  ? 65  ASN A O   1 
ATOM   475  C  CB  . ASN A 1 65  ? 6.953   -8.317  -15.427 1.00 50.14  ? 65  ASN A CB  1 
ATOM   476  C  CG  . ASN A 1 65  ? 6.633   -8.117  -13.967 1.00 65.01  ? 65  ASN A CG  1 
ATOM   477  O  OD1 . ASN A 1 65  ? 6.040   -8.969  -13.298 1.00 59.58  ? 65  ASN A OD1 1 
ATOM   478  N  ND2 . ASN A 1 65  ? 7.056   -6.983  -13.439 1.00 59.67  ? 65  ASN A ND2 1 
ATOM   479  N  N   . PRO A 1 66  ? 3.448   -8.872  -16.830 1.00 50.43  ? 66  PRO A N   1 
ATOM   480  C  CA  . PRO A 1 66  ? 2.179   -8.121  -16.925 1.00 52.21  ? 66  PRO A CA  1 
ATOM   481  C  C   . PRO A 1 66  ? 1.504   -7.822  -15.586 1.00 59.65  ? 66  PRO A C   1 
ATOM   482  O  O   . PRO A 1 66  ? 0.752   -6.847  -15.489 1.00 60.51  ? 66  PRO A O   1 
ATOM   483  C  CB  . PRO A 1 66  ? 1.299   -8.997  -17.829 1.00 53.49  ? 66  PRO A CB  1 
ATOM   484  C  CG  . PRO A 1 66  ? 1.815   -10.370 -17.640 1.00 56.53  ? 66  PRO A CG  1 
ATOM   485  C  CD  . PRO A 1 66  ? 3.286   -10.266 -17.295 1.00 50.44  ? 66  PRO A CD  1 
ATOM   486  N  N   . LEU A 1 67  ? 1.778   -8.651  -14.556 1.00 57.02  ? 67  LEU A N   1 
ATOM   487  C  CA  . LEU A 1 67  ? 1.202   -8.483  -13.221 1.00 58.84  ? 67  LEU A CA  1 
ATOM   488  C  C   . LEU A 1 67  ? 2.021   -7.537  -12.318 1.00 63.08  ? 67  LEU A C   1 
ATOM   489  O  O   . LEU A 1 67  ? 1.686   -7.381  -11.137 1.00 63.36  ? 67  LEU A O   1 
ATOM   490  C  CB  . LEU A 1 67  ? 0.951   -9.845  -12.531 1.00 59.43  ? 67  LEU A CB  1 
ATOM   491  C  CG  . LEU A 1 67  ? -0.001  -10.847 -13.217 1.00 64.68  ? 67  LEU A CG  1 
ATOM   492  C  CD1 . LEU A 1 67  ? -0.170  -12.092 -12.367 1.00 65.51  ? 67  LEU A CD1 1 
ATOM   493  C  CD2 . LEU A 1 67  ? -1.366  -10.239 -13.488 1.00 69.54  ? 67  LEU A CD2 1 
ATOM   494  N  N   . SER A 1 68  ? 3.075   -6.891  -12.887 1.00 58.47  ? 68  SER A N   1 
ATOM   495  C  CA  . SER A 1 68  ? 3.964   -5.932  -12.215 1.00 59.29  ? 68  SER A CA  1 
ATOM   496  C  C   . SER A 1 68  ? 4.521   -6.444  -10.863 1.00 63.72  ? 68  SER A C   1 
ATOM   497  O  O   . SER A 1 68  ? 4.509   -5.718  -9.868  1.00 65.38  ? 68  SER A O   1 
ATOM   498  C  CB  . SER A 1 68  ? 3.277   -4.573  -12.067 1.00 64.27  ? 68  SER A CB  1 
ATOM   499  O  OG  . SER A 1 68  ? 2.899   -4.049  -13.329 1.00 71.60  ? 68  SER A OG  1 
ATOM   500  N  N   . ARG A 1 69  ? 5.000   -7.700  -10.837 1.00 58.65  ? 69  ARG A N   1 
ATOM   501  C  CA  . ARG A 1 69  ? 5.559   -8.317  -9.627  1.00 58.90  ? 69  ARG A CA  1 
ATOM   502  C  C   . ARG A 1 69  ? 7.076   -8.160  -9.594  1.00 60.95  ? 69  ARG A C   1 
ATOM   503  O  O   . ARG A 1 69  ? 7.683   -7.757  -10.592 1.00 58.85  ? 69  ARG A O   1 
ATOM   504  C  CB  . ARG A 1 69  ? 5.187   -9.814  -9.540  1.00 58.65  ? 69  ARG A CB  1 
ATOM   505  C  CG  . ARG A 1 69  ? 3.691   -10.106 -9.654  1.00 66.27  ? 69  ARG A CG  1 
ATOM   506  C  CD  . ARG A 1 69  ? 2.997   -10.201 -8.319  1.00 77.66  ? 69  ARG A CD  1 
ATOM   507  N  NE  . ARG A 1 69  ? 1.542   -10.243 -8.477  1.00 92.30  ? 69  ARG A NE  1 
ATOM   508  C  CZ  . ARG A 1 69  ? 0.825   -11.358 -8.588  1.00 107.62 ? 69  ARG A CZ  1 
ATOM   509  N  NH1 . ARG A 1 69  ? 1.421   -12.545 -8.555  1.00 92.18  ? 69  ARG A NH1 1 
ATOM   510  N  NH2 . ARG A 1 69  ? -0.492  -11.296 -8.729  1.00 96.61  ? 69  ARG A NH2 1 
ATOM   511  N  N   . LYS A 1 70  ? 7.683   -8.462  -8.436  1.00 57.93  ? 70  LYS A N   1 
ATOM   512  C  CA  . LYS A 1 70  ? 9.130   -8.427  -8.255  1.00 56.88  ? 70  LYS A CA  1 
ATOM   513  C  C   . LYS A 1 70  ? 9.726   -9.689  -8.896  1.00 58.60  ? 70  LYS A C   1 
ATOM   514  O  O   . LYS A 1 70  ? 9.033   -10.699 -9.036  1.00 57.22  ? 70  LYS A O   1 
ATOM   515  C  CB  . LYS A 1 70  ? 9.479   -8.366  -6.752  1.00 60.48  ? 70  LYS A CB  1 
ATOM   516  C  CG  . LYS A 1 70  ? 9.391   -6.967  -6.152  1.00 72.36  ? 70  LYS A CG  1 
ATOM   517  C  CD  . LYS A 1 70  ? 9.303   -7.035  -4.631  1.00 89.02  ? 70  LYS A CD  1 
ATOM   518  C  CE  . LYS A 1 70  ? 9.367   -5.680  -3.967  1.00 108.69 ? 70  LYS A CE  1 
ATOM   519  N  NZ  . LYS A 1 70  ? 10.765  -5.184  -3.846  1.00 122.58 ? 70  LYS A NZ  1 
ATOM   520  N  N   . HIS A 1 71  ? 10.992  -9.624  -9.313  1.00 55.57  ? 71  HIS A N   1 
ATOM   521  C  CA  . HIS A 1 71  ? 11.684  -10.770 -9.899  1.00 53.15  ? 71  HIS A CA  1 
ATOM   522  C  C   . HIS A 1 71  ? 11.893  -11.866 -8.820  1.00 58.67  ? 71  HIS A C   1 
ATOM   523  O  O   . HIS A 1 71  ? 12.121  -11.553 -7.650  1.00 57.43  ? 71  HIS A O   1 
ATOM   524  C  CB  . HIS A 1 71  ? 13.018  -10.326 -10.518 1.00 52.87  ? 71  HIS A CB  1 
ATOM   525  C  CG  . HIS A 1 71  ? 13.837  -11.454 -11.052 1.00 54.79  ? 71  HIS A CG  1 
ATOM   526  N  ND1 . HIS A 1 71  ? 13.514  -12.078 -12.233 1.00 54.78  ? 71  HIS A ND1 1 
ATOM   527  C  CD2 . HIS A 1 71  ? 14.904  -12.077 -10.504 1.00 57.05  ? 71  HIS A CD2 1 
ATOM   528  C  CE1 . HIS A 1 71  ? 14.398  -13.046 -12.382 1.00 53.96  ? 71  HIS A CE1 1 
ATOM   529  N  NE2 . HIS A 1 71  ? 15.260  -13.077 -11.370 1.00 55.69  ? 71  HIS A NE2 1 
ATOM   530  N  N   . GLY A 1 72  ? 11.758  -13.124 -9.230  1.00 55.82  ? 72  GLY A N   1 
ATOM   531  C  CA  . GLY A 1 72  ? 11.960  -14.287 -8.372  1.00 56.91  ? 72  GLY A CA  1 
ATOM   532  C  C   . GLY A 1 72  ? 12.264  -15.525 -9.194  1.00 61.82  ? 72  GLY A C   1 
ATOM   533  O  O   . GLY A 1 72  ? 12.364  -15.451 -10.424 1.00 60.43  ? 72  GLY A O   1 
ATOM   534  N  N   . GLY A 1 73  ? 12.418  -16.657 -8.516  1.00 59.76  ? 73  GLY A N   1 
ATOM   535  C  CA  . GLY A 1 73  ? 12.648  -17.941 -9.173  1.00 58.98  ? 73  GLY A CA  1 
ATOM   536  C  C   . GLY A 1 73  ? 11.337  -18.509 -9.694  1.00 60.21  ? 73  GLY A C   1 
ATOM   537  O  O   . GLY A 1 73  ? 10.279  -18.055 -9.255  1.00 59.00  ? 73  GLY A O   1 
ATOM   538  N  N   . PRO A 1 74  ? 11.357  -19.510 -10.617 1.00 56.81  ? 74  PRO A N   1 
ATOM   539  C  CA  . PRO A 1 74  ? 10.091  -20.050 -11.154 1.00 56.76  ? 74  PRO A CA  1 
ATOM   540  C  C   . PRO A 1 74  ? 9.188   -20.754 -10.135 1.00 62.72  ? 74  PRO A C   1 
ATOM   541  O  O   . PRO A 1 74  ? 7.978   -20.843 -10.360 1.00 61.61  ? 74  PRO A O   1 
ATOM   542  C  CB  . PRO A 1 74  ? 10.542  -20.995 -12.273 1.00 58.26  ? 74  PRO A CB  1 
ATOM   543  C  CG  . PRO A 1 74  ? 11.937  -21.350 -11.941 1.00 63.35  ? 74  PRO A CG  1 
ATOM   544  C  CD  . PRO A 1 74  ? 12.526  -20.164 -11.241 1.00 58.52  ? 74  PRO A CD  1 
ATOM   545  N  N   . LYS A 1 75  ? 9.772   -21.241 -9.021  1.00 60.23  ? 75  LYS A N   1 
ATOM   546  C  CA  . LYS A 1 75  ? 9.035   -21.920 -7.949  1.00 62.31  ? 75  LYS A CA  1 
ATOM   547  C  C   . LYS A 1 75  ? 8.371   -20.938 -6.959  1.00 66.08  ? 75  LYS A C   1 
ATOM   548  O  O   . LYS A 1 75  ? 7.530   -21.354 -6.160  1.00 67.54  ? 75  LYS A O   1 
ATOM   549  C  CB  . LYS A 1 75  ? 9.946   -22.922 -7.211  1.00 66.56  ? 75  LYS A CB  1 
ATOM   550  C  CG  . LYS A 1 75  ? 10.282  -24.164 -8.029  1.00 84.69  ? 75  LYS A CG  1 
ATOM   551  C  CD  . LYS A 1 75  ? 10.887  -25.255 -7.163  1.00 100.98 ? 75  LYS A CD  1 
ATOM   552  C  CE  . LYS A 1 75  ? 11.078  -26.543 -7.925  1.00 115.98 ? 75  LYS A CE  1 
ATOM   553  N  NZ  . LYS A 1 75  ? 11.579  -27.631 -7.043  1.00 127.91 ? 75  LYS A NZ  1 
ATOM   554  N  N   . ASP A 1 76  ? 8.736   -19.642 -7.026  1.00 61.19  ? 76  ASP A N   1 
ATOM   555  C  CA  . ASP A 1 76  ? 8.220   -18.591 -6.140  1.00 61.53  ? 76  ASP A CA  1 
ATOM   556  C  C   . ASP A 1 76  ? 6.848   -18.069 -6.541  1.00 64.30  ? 76  ASP A C   1 
ATOM   557  O  O   . ASP A 1 76  ? 6.515   -18.045 -7.727  1.00 63.26  ? 76  ASP A O   1 
ATOM   558  C  CB  . ASP A 1 76  ? 9.203   -17.401 -6.087  1.00 62.50  ? 76  ASP A CB  1 
ATOM   559  C  CG  . ASP A 1 76  ? 10.572  -17.700 -5.513  1.00 70.73  ? 76  ASP A CG  1 
ATOM   560  O  OD1 . ASP A 1 76  ? 10.707  -18.710 -4.784  1.00 74.02  ? 76  ASP A OD1 1 
ATOM   561  O  OD2 . ASP A 1 76  ? 11.502  -16.917 -5.773  1.00 72.06  ? 76  ASP A OD2 1 
ATOM   562  N  N   . GLU A 1 77  ? 6.079   -17.593 -5.548  1.00 60.84  ? 77  GLU A N   1 
ATOM   563  C  CA  . GLU A 1 77  ? 4.772   -16.968 -5.749  1.00 60.89  ? 77  GLU A CA  1 
ATOM   564  C  C   . GLU A 1 77  ? 4.997   -15.554 -6.316  1.00 63.65  ? 77  GLU A C   1 
ATOM   565  O  O   . GLU A 1 77  ? 4.253   -15.116 -7.198  1.00 63.12  ? 77  GLU A O   1 
ATOM   566  C  CB  . GLU A 1 77  ? 3.969   -16.926 -4.422  1.00 64.26  ? 77  GLU A CB  1 
ATOM   567  C  CG  . GLU A 1 77  ? 2.602   -16.260 -4.525  1.00 76.12  ? 77  GLU A CG  1 
ATOM   568  C  CD  . GLU A 1 77  ? 1.505   -17.052 -5.212  1.00 99.96  ? 77  GLU A CD  1 
ATOM   569  O  OE1 . GLU A 1 77  ? 0.583   -17.518 -4.505  1.00 96.40  ? 77  GLU A OE1 1 
ATOM   570  O  OE2 . GLU A 1 77  ? 1.554   -17.190 -6.457  1.00 91.76  ? 77  GLU A OE2 1 
ATOM   571  N  N   . GLU A 1 78  ? 6.032   -14.854 -5.807  1.00 59.63  ? 78  GLU A N   1 
ATOM   572  C  CA  . GLU A 1 78  ? 6.403   -13.522 -6.277  1.00 58.58  ? 78  GLU A CA  1 
ATOM   573  C  C   . GLU A 1 78  ? 7.439   -13.678 -7.395  1.00 58.63  ? 78  GLU A C   1 
ATOM   574  O  O   . GLU A 1 78  ? 8.616   -13.934 -7.131  1.00 56.62  ? 78  GLU A O   1 
ATOM   575  C  CB  . GLU A 1 78  ? 6.925   -12.646 -5.122  1.00 61.24  ? 78  GLU A CB  1 
ATOM   576  C  CG  . GLU A 1 78  ? 7.107   -11.174 -5.476  1.00 70.22  ? 78  GLU A CG  1 
ATOM   577  C  CD  . GLU A 1 78  ? 5.863   -10.322 -5.667  1.00 84.14  ? 78  GLU A CD  1 
ATOM   578  O  OE1 . GLU A 1 78  ? 6.008   -9.194  -6.190  1.00 62.97  ? 78  GLU A OE1 1 
ATOM   579  O  OE2 . GLU A 1 78  ? 4.753   -10.762 -5.289  1.00 83.84  ? 78  GLU A OE2 1 
ATOM   580  N  N   . ARG A 1 79  ? 6.976   -13.582 -8.645  1.00 55.03  ? 79  ARG A N   1 
ATOM   581  C  CA  . ARG A 1 79  ? 7.818   -13.725 -9.839  1.00 53.35  ? 79  ARG A CA  1 
ATOM   582  C  C   . ARG A 1 79  ? 7.151   -13.064 -11.039 1.00 56.02  ? 79  ARG A C   1 
ATOM   583  O  O   . ARG A 1 79  ? 5.926   -12.896 -11.051 1.00 57.01  ? 79  ARG A O   1 
ATOM   584  C  CB  . ARG A 1 79  ? 8.081   -15.221 -10.165 1.00 52.04  ? 79  ARG A CB  1 
ATOM   585  C  CG  . ARG A 1 79  ? 6.812   -16.059 -10.413 1.00 51.57  ? 79  ARG A CG  1 
ATOM   586  C  CD  . ARG A 1 79  ? 7.122   -17.392 -11.057 1.00 53.80  ? 79  ARG A CD  1 
ATOM   587  N  NE  . ARG A 1 79  ? 7.155   -17.295 -12.517 1.00 55.75  ? 79  ARG A NE  1 
ATOM   588  C  CZ  . ARG A 1 79  ? 7.164   -18.337 -13.341 1.00 60.11  ? 79  ARG A CZ  1 
ATOM   589  N  NH1 . ARG A 1 79  ? 7.143   -19.572 -12.860 1.00 45.94  ? 79  ARG A NH1 1 
ATOM   590  N  NH2 . ARG A 1 79  ? 7.172   -18.152 -14.652 1.00 47.96  ? 79  ARG A NH2 1 
ATOM   591  N  N   . HIS A 1 80  ? 7.950   -12.714 -12.054 1.00 50.51  ? 80  HIS A N   1 
ATOM   592  C  CA  . HIS A 1 80  ? 7.432   -12.194 -13.327 1.00 48.73  ? 80  HIS A CA  1 
ATOM   593  C  C   . HIS A 1 80  ? 6.877   -13.414 -14.062 1.00 50.51  ? 80  HIS A C   1 
ATOM   594  O  O   . HIS A 1 80  ? 7.326   -14.536 -13.800 1.00 48.85  ? 80  HIS A O   1 
ATOM   595  C  CB  . HIS A 1 80  ? 8.569   -11.610 -14.190 1.00 48.32  ? 80  HIS A CB  1 
ATOM   596  C  CG  . HIS A 1 80  ? 9.378   -10.512 -13.571 1.00 52.15  ? 80  HIS A CG  1 
ATOM   597  N  ND1 . HIS A 1 80  ? 10.606  -10.161 -14.086 1.00 53.36  ? 80  HIS A ND1 1 
ATOM   598  C  CD2 . HIS A 1 80  ? 9.120   -9.731  -12.498 1.00 55.17  ? 80  HIS A CD2 1 
ATOM   599  C  CE1 . HIS A 1 80  ? 11.044  -9.166  -13.335 1.00 53.88  ? 80  HIS A CE1 1 
ATOM   600  N  NE2 . HIS A 1 80  ? 10.182  -8.873  -12.366 1.00 55.36  ? 80  HIS A NE2 1 
ATOM   601  N  N   . VAL A 1 81  ? 5.980   -13.214 -15.033 1.00 48.42  ? 81  VAL A N   1 
ATOM   602  C  CA  . VAL A 1 81  ? 5.493   -14.342 -15.835 1.00 48.28  ? 81  VAL A CA  1 
ATOM   603  C  C   . VAL A 1 81  ? 6.696   -14.992 -16.587 1.00 51.09  ? 81  VAL A C   1 
ATOM   604  O  O   . VAL A 1 81  ? 6.808   -16.218 -16.638 1.00 51.05  ? 81  VAL A O   1 
ATOM   605  C  CB  . VAL A 1 81  ? 4.309   -13.942 -16.769 1.00 51.83  ? 81  VAL A CB  1 
ATOM   606  C  CG1 . VAL A 1 81  ? 4.044   -15.005 -17.830 1.00 51.47  ? 81  VAL A CG1 1 
ATOM   607  C  CG2 . VAL A 1 81  ? 3.036   -13.676 -15.957 1.00 53.11  ? 81  VAL A CG2 1 
ATOM   608  N  N   . GLY A 1 82  ? 7.612   -14.158 -17.078 1.00 46.91  ? 82  GLY A N   1 
ATOM   609  C  CA  . GLY A 1 82  ? 8.790   -14.597 -17.819 1.00 45.32  ? 82  GLY A CA  1 
ATOM   610  C  C   . GLY A 1 82  ? 9.933   -15.205 -17.023 1.00 48.13  ? 82  GLY A C   1 
ATOM   611  O  O   . GLY A 1 82  ? 10.916  -15.629 -17.626 1.00 46.93  ? 82  GLY A O   1 
ATOM   612  N  N   . ASP A 1 83  ? 9.821   -15.281 -15.672 1.00 45.83  ? 83  ASP A N   1 
ATOM   613  C  CA  . ASP A 1 83  ? 10.887  -15.813 -14.801 1.00 46.19  ? 83  ASP A CA  1 
ATOM   614  C  C   . ASP A 1 83  ? 11.031  -17.338 -14.868 1.00 51.97  ? 83  ASP A C   1 
ATOM   615  O  O   . ASP A 1 83  ? 10.511  -18.052 -14.004 1.00 53.55  ? 83  ASP A O   1 
ATOM   616  C  CB  . ASP A 1 83  ? 10.689  -15.336 -13.347 1.00 47.64  ? 83  ASP A CB  1 
ATOM   617  C  CG  . ASP A 1 83  ? 11.043  -13.883 -13.105 1.00 51.65  ? 83  ASP A CG  1 
ATOM   618  O  OD1 . ASP A 1 83  ? 11.698  -13.272 -13.986 1.00 51.73  ? 83  ASP A OD1 1 
ATOM   619  O  OD2 . ASP A 1 83  ? 10.680  -13.356 -12.032 1.00 54.68  ? 83  ASP A OD2 1 
ATOM   620  N  N   . LEU A 1 84  ? 11.759  -17.837 -15.878 1.00 47.21  ? 84  LEU A N   1 
ATOM   621  C  CA  . LEU A 1 84  ? 11.935  -19.282 -16.047 1.00 47.60  ? 84  LEU A CA  1 
ATOM   622  C  C   . LEU A 1 84  ? 13.220  -19.825 -15.409 1.00 52.12  ? 84  LEU A C   1 
ATOM   623  O  O   . LEU A 1 84  ? 13.614  -20.960 -15.687 1.00 53.75  ? 84  LEU A O   1 
ATOM   624  C  CB  . LEU A 1 84  ? 11.817  -19.700 -17.522 1.00 47.14  ? 84  LEU A CB  1 
ATOM   625  C  CG  . LEU A 1 84  ? 10.472  -19.437 -18.205 1.00 50.50  ? 84  LEU A CG  1 
ATOM   626  C  CD1 . LEU A 1 84  ? 10.560  -19.781 -19.677 1.00 49.29  ? 84  LEU A CD1 1 
ATOM   627  C  CD2 . LEU A 1 84  ? 9.336   -20.214 -17.532 1.00 54.28  ? 84  LEU A CD2 1 
ATOM   628  N  N   . GLY A 1 85  ? 13.823  -19.023 -14.537 1.00 47.26  ? 85  GLY A N   1 
ATOM   629  C  CA  . GLY A 1 85  ? 15.025  -19.376 -13.794 1.00 48.81  ? 85  GLY A CA  1 
ATOM   630  C  C   . GLY A 1 85  ? 16.309  -19.509 -14.588 1.00 51.69  ? 85  GLY A C   1 
ATOM   631  O  O   . GLY A 1 85  ? 16.692  -18.605 -15.337 1.00 48.77  ? 85  GLY A O   1 
ATOM   632  N  N   . ASN A 1 86  ? 17.010  -20.630 -14.363 1.00 50.45  ? 86  ASN A N   1 
ATOM   633  C  CA  . ASN A 1 86  ? 18.302  -20.928 -14.970 1.00 50.88  ? 86  ASN A CA  1 
ATOM   634  C  C   . ASN A 1 86  ? 18.335  -22.225 -15.741 1.00 55.80  ? 86  ASN A C   1 
ATOM   635  O  O   . ASN A 1 86  ? 17.652  -23.189 -15.385 1.00 56.17  ? 86  ASN A O   1 
ATOM   636  C  CB  . ASN A 1 86  ? 19.386  -21.014 -13.873 1.00 51.13  ? 86  ASN A CB  1 
ATOM   637  C  CG  . ASN A 1 86  ? 19.795  -19.694 -13.291 1.00 56.33  ? 86  ASN A CG  1 
ATOM   638  O  OD1 . ASN A 1 86  ? 20.249  -18.802 -14.000 1.00 49.16  ? 86  ASN A OD1 1 
ATOM   639  N  ND2 . ASN A 1 86  ? 19.671  -19.553 -11.989 1.00 53.10  ? 86  ASN A ND2 1 
ATOM   640  N  N   . VAL A 1 87  ? 19.192  -22.260 -16.773 1.00 52.66  ? 87  VAL A N   1 
ATOM   641  C  CA  . VAL A 1 87  ? 19.506  -23.466 -17.533 1.00 53.61  ? 87  VAL A CA  1 
ATOM   642  C  C   . VAL A 1 87  ? 20.933  -23.846 -17.126 1.00 57.67  ? 87  VAL A C   1 
ATOM   643  O  O   . VAL A 1 87  ? 21.694  -22.960 -16.737 1.00 56.89  ? 87  VAL A O   1 
ATOM   644  C  CB  . VAL A 1 87  ? 19.309  -23.329 -19.066 1.00 57.20  ? 87  VAL A CB  1 
ATOM   645  C  CG1 . VAL A 1 87  ? 17.835  -23.158 -19.406 1.00 55.70  ? 87  VAL A CG1 1 
ATOM   646  C  CG2 . VAL A 1 87  ? 20.145  -22.191 -19.657 1.00 56.57  ? 87  VAL A CG2 1 
ATOM   647  N  N   . THR A 1 88  ? 21.289  -25.136 -17.158 1.00 56.66  ? 88  THR A N   1 
ATOM   648  C  CA  . THR A 1 88  ? 22.640  -25.533 -16.754 1.00 58.92  ? 88  THR A CA  1 
ATOM   649  C  C   . THR A 1 88  ? 23.425  -26.123 -17.934 1.00 64.44  ? 88  THR A C   1 
ATOM   650  O  O   . THR A 1 88  ? 23.009  -27.114 -18.544 1.00 64.53  ? 88  THR A O   1 
ATOM   651  C  CB  . THR A 1 88  ? 22.652  -26.418 -15.470 1.00 73.51  ? 88  THR A CB  1 
ATOM   652  O  OG1 . THR A 1 88  ? 23.993  -26.844 -15.187 1.00 76.76  ? 88  THR A OG1 1 
ATOM   653  C  CG2 . THR A 1 88  ? 21.717  -27.630 -15.543 1.00 73.87  ? 88  THR A CG2 1 
ATOM   654  N  N   . ALA A 1 89  ? 24.561  -25.470 -18.254 1.00 61.00  ? 89  ALA A N   1 
ATOM   655  C  CA  . ALA A 1 89  ? 25.503  -25.864 -19.300 1.00 62.37  ? 89  ALA A CA  1 
ATOM   656  C  C   . ALA A 1 89  ? 26.596  -26.741 -18.699 1.00 69.47  ? 89  ALA A C   1 
ATOM   657  O  O   . ALA A 1 89  ? 27.144  -26.398 -17.651 1.00 69.22  ? 89  ALA A O   1 
ATOM   658  C  CB  . ALA A 1 89  ? 26.135  -24.628 -19.919 1.00 62.21  ? 89  ALA A CB  1 
ATOM   659  N  N   . ASP A 1 90  ? 26.929  -27.856 -19.375 1.00 69.70  ? 90  ASP A N   1 
ATOM   660  C  CA  . ASP A 1 90  ? 28.002  -28.769 -18.966 1.00 73.41  ? 90  ASP A CA  1 
ATOM   661  C  C   . ASP A 1 90  ? 29.381  -28.215 -19.392 1.00 80.30  ? 90  ASP A C   1 
ATOM   662  O  O   . ASP A 1 90  ? 29.445  -27.137 -19.996 1.00 78.04  ? 90  ASP A O   1 
ATOM   663  C  CB  . ASP A 1 90  ? 27.768  -30.196 -19.526 1.00 76.83  ? 90  ASP A CB  1 
ATOM   664  C  CG  . ASP A 1 90  ? 27.639  -30.342 -21.040 1.00 81.42  ? 90  ASP A CG  1 
ATOM   665  O  OD1 . ASP A 1 90  ? 28.164  -29.477 -21.773 1.00 79.36  ? 90  ASP A OD1 1 
ATOM   666  O  OD2 . ASP A 1 90  ? 27.033  -31.336 -21.489 1.00 87.98  ? 90  ASP A OD2 1 
ATOM   667  N  N   . LYS A 1 91  ? 30.471  -28.968 -19.112 1.00 80.95  ? 91  LYS A N   1 
ATOM   668  C  CA  . LYS A 1 91  ? 31.855  -28.602 -19.461 1.00 83.30  ? 91  LYS A CA  1 
ATOM   669  C  C   . LYS A 1 91  ? 32.094  -28.404 -20.971 1.00 86.41  ? 91  LYS A C   1 
ATOM   670  O  O   . LYS A 1 91  ? 33.063  -27.739 -21.349 1.00 87.07  ? 91  LYS A O   1 
ATOM   671  C  CB  . LYS A 1 91  ? 32.874  -29.601 -18.873 1.00 90.44  ? 91  LYS A CB  1 
ATOM   672  C  CG  . LYS A 1 91  ? 32.797  -31.027 -19.424 1.00 111.04 ? 91  LYS A CG  1 
ATOM   673  C  CD  . LYS A 1 91  ? 32.165  -31.976 -18.415 1.00 124.15 ? 91  LYS A CD  1 
ATOM   674  C  CE  . LYS A 1 91  ? 32.600  -33.405 -18.626 1.00 138.62 ? 91  LYS A CE  1 
ATOM   675  N  NZ  . LYS A 1 91  ? 32.058  -34.304 -17.572 1.00 149.01 ? 91  LYS A NZ  1 
ATOM   676  N  N   . ASP A 1 92  ? 31.217  -28.980 -21.817 1.00 80.94  ? 92  ASP A N   1 
ATOM   677  C  CA  . ASP A 1 92  ? 31.282  -28.888 -23.279 1.00 80.02  ? 92  ASP A CA  1 
ATOM   678  C  C   . ASP A 1 92  ? 30.433  -27.728 -23.835 1.00 78.98  ? 92  ASP A C   1 
ATOM   679  O  O   . ASP A 1 92  ? 30.335  -27.560 -25.052 1.00 77.82  ? 92  ASP A O   1 
ATOM   680  C  CB  . ASP A 1 92  ? 30.874  -30.229 -23.920 1.00 83.35  ? 92  ASP A CB  1 
ATOM   681  C  CG  . ASP A 1 92  ? 31.729  -31.402 -23.483 1.00 96.67  ? 92  ASP A CG  1 
ATOM   682  O  OD1 . ASP A 1 92  ? 32.904  -31.477 -23.915 1.00 100.00 ? 92  ASP A OD1 1 
ATOM   683  O  OD2 . ASP A 1 92  ? 31.225  -32.247 -22.711 1.00 102.56 ? 92  ASP A OD2 1 
ATOM   684  N  N   . GLY A 1 93  ? 29.855  -26.936 -22.939 1.00 72.78  ? 93  GLY A N   1 
ATOM   685  C  CA  . GLY A 1 93  ? 29.020  -25.789 -23.280 1.00 69.16  ? 93  GLY A CA  1 
ATOM   686  C  C   . GLY A 1 93  ? 27.577  -26.082 -23.646 1.00 69.10  ? 93  GLY A C   1 
ATOM   687  O  O   . GLY A 1 93  ? 26.865  -25.171 -24.074 1.00 65.54  ? 93  GLY A O   1 
ATOM   688  N  N   . VAL A 1 94  ? 27.122  -27.336 -23.455 1.00 66.39  ? 94  VAL A N   1 
ATOM   689  C  CA  . VAL A 1 94  ? 25.767  -27.773 -23.808 1.00 64.80  ? 94  VAL A CA  1 
ATOM   690  C  C   . VAL A 1 94  ? 24.809  -27.755 -22.598 1.00 67.87  ? 94  VAL A C   1 
ATOM   691  O  O   . VAL A 1 94  ? 25.092  -28.367 -21.562 1.00 68.81  ? 94  VAL A O   1 
ATOM   692  C  CB  . VAL A 1 94  ? 25.769  -29.148 -24.544 1.00 70.71  ? 94  VAL A CB  1 
ATOM   693  C  CG1 . VAL A 1 94  ? 24.356  -29.564 -24.963 1.00 69.31  ? 94  VAL A CG1 1 
ATOM   694  C  CG2 . VAL A 1 94  ? 26.697  -29.123 -25.759 1.00 71.64  ? 94  VAL A CG2 1 
ATOM   695  N  N   . ALA A 1 95  ? 23.666  -27.066 -22.758 1.00 61.88  ? 95  ALA A N   1 
ATOM   696  C  CA  . ALA A 1 95  ? 22.624  -26.973 -21.732 1.00 60.97  ? 95  ALA A CA  1 
ATOM   697  C  C   . ALA A 1 95  ? 21.381  -27.736 -22.163 1.00 65.95  ? 95  ALA A C   1 
ATOM   698  O  O   . ALA A 1 95  ? 20.706  -27.328 -23.105 1.00 63.95  ? 95  ALA A O   1 
ATOM   699  C  CB  . ALA A 1 95  ? 22.282  -25.516 -21.437 1.00 59.06  ? 95  ALA A CB  1 
ATOM   700  N  N   . ASP A 1 96  ? 21.114  -28.873 -21.508 1.00 66.51  ? 96  ASP A N   1 
ATOM   701  C  CA  . ASP A 1 96  ? 19.929  -29.689 -21.771 1.00 67.65  ? 96  ASP A CA  1 
ATOM   702  C  C   . ASP A 1 96  ? 18.776  -29.087 -20.964 1.00 69.30  ? 96  ASP A C   1 
ATOM   703  O  O   . ASP A 1 96  ? 18.891  -28.927 -19.746 1.00 68.63  ? 96  ASP A O   1 
ATOM   704  C  CB  . ASP A 1 96  ? 20.167  -31.159 -21.390 1.00 73.38  ? 96  ASP A CB  1 
ATOM   705  C  CG  . ASP A 1 96  ? 19.491  -32.127 -22.339 1.00 90.58  ? 96  ASP A CG  1 
ATOM   706  O  OD1 . ASP A 1 96  ? 20.206  -32.760 -23.151 1.00 94.67  ? 96  ASP A OD1 1 
ATOM   707  O  OD2 . ASP A 1 96  ? 18.245  -32.243 -22.282 1.00 96.21  ? 96  ASP A OD2 1 
ATOM   708  N  N   . VAL A 1 97  ? 17.696  -28.695 -21.656 1.00 64.42  ? 97  VAL A N   1 
ATOM   709  C  CA  . VAL A 1 97  ? 16.543  -28.035 -21.037 1.00 62.56  ? 97  VAL A CA  1 
ATOM   710  C  C   . VAL A 1 97  ? 15.340  -28.974 -20.961 1.00 68.21  ? 97  VAL A C   1 
ATOM   711  O  O   . VAL A 1 97  ? 14.962  -29.577 -21.965 1.00 68.13  ? 97  VAL A O   1 
ATOM   712  C  CB  . VAL A 1 97  ? 16.203  -26.701 -21.767 1.00 63.53  ? 97  VAL A CB  1 
ATOM   713  C  CG1 . VAL A 1 97  ? 15.063  -25.954 -21.077 1.00 61.74  ? 97  VAL A CG1 1 
ATOM   714  C  CG2 . VAL A 1 97  ? 17.435  -25.806 -21.891 1.00 62.35  ? 97  VAL A CG2 1 
ATOM   715  N  N   . SER A 1 98  ? 14.766  -29.110 -19.754 1.00 65.91  ? 98  SER A N   1 
ATOM   716  C  CA  . SER A 1 98  ? 13.565  -29.897 -19.475 1.00 67.28  ? 98  SER A CA  1 
ATOM   717  C  C   . SER A 1 98  ? 12.857  -29.241 -18.281 1.00 70.91  ? 98  SER A C   1 
ATOM   718  O  O   . SER A 1 98  ? 13.111  -29.577 -17.120 1.00 71.22  ? 98  SER A O   1 
ATOM   719  C  CB  . SER A 1 98  ? 13.897  -31.366 -19.225 1.00 73.63  ? 98  SER A CB  1 
ATOM   720  O  OG  . SER A 1 98  ? 12.899  -32.201 -19.791 1.00 82.09  ? 98  SER A OG  1 
ATOM   721  N  N   . ILE A 1 99  ? 12.027  -28.232 -18.590 1.00 65.94  ? 99  ILE A N   1 
ATOM   722  C  CA  . ILE A 1 99  ? 11.295  -27.421 -17.614 1.00 65.38  ? 99  ILE A CA  1 
ATOM   723  C  C   . ILE A 1 99  ? 9.791   -27.589 -17.826 1.00 68.95  ? 99  ILE A C   1 
ATOM   724  O  O   . ILE A 1 99  ? 9.337   -27.778 -18.958 1.00 68.85  ? 99  ILE A O   1 
ATOM   725  C  CB  . ILE A 1 99  ? 11.744  -25.920 -17.738 1.00 66.45  ? 99  ILE A CB  1 
ATOM   726  C  CG1 . ILE A 1 99  ? 13.232  -25.733 -17.335 1.00 67.15  ? 99  ILE A CG1 1 
ATOM   727  C  CG2 . ILE A 1 99  ? 10.826  -24.945 -16.963 1.00 65.92  ? 99  ILE A CG2 1 
ATOM   728  C  CD1 . ILE A 1 99  ? 13.894  -24.417 -17.836 1.00 71.89  ? 99  ILE A CD1 1 
ATOM   729  N  N   . GLU A 1 100 ? 9.035   -27.519 -16.730 1.00 64.66  ? 100 GLU A N   1 
ATOM   730  C  CA  . GLU A 1 100 ? 7.580   -27.543 -16.701 1.00 64.36  ? 100 GLU A CA  1 
ATOM   731  C  C   . GLU A 1 100 ? 7.180   -26.295 -15.907 1.00 65.30  ? 100 GLU A C   1 
ATOM   732  O  O   . GLU A 1 100 ? 7.687   -26.090 -14.800 1.00 64.71  ? 100 GLU A O   1 
ATOM   733  C  CB  . GLU A 1 100 ? 7.070   -28.832 -16.040 1.00 68.73  ? 100 GLU A CB  1 
ATOM   734  C  CG  . GLU A 1 100 ? 5.629   -29.170 -16.387 1.00 81.28  ? 100 GLU A CG  1 
ATOM   735  C  CD  . GLU A 1 100 ? 5.140   -30.480 -15.802 1.00 107.49 ? 100 GLU A CD  1 
ATOM   736  O  OE1 . GLU A 1 100 ? 4.982   -31.450 -16.578 1.00 106.18 ? 100 GLU A OE1 1 
ATOM   737  O  OE2 . GLU A 1 100 ? 4.918   -30.542 -14.571 1.00 101.11 ? 100 GLU A OE2 1 
ATOM   738  N  N   . ASP A 1 101 ? 6.362   -25.414 -16.511 1.00 60.06  ? 101 ASP A N   1 
ATOM   739  C  CA  . ASP A 1 101 ? 5.934   -24.165 -15.876 1.00 58.48  ? 101 ASP A CA  1 
ATOM   740  C  C   . ASP A 1 101 ? 4.435   -23.950 -15.996 1.00 63.08  ? 101 ASP A C   1 
ATOM   741  O  O   . ASP A 1 101 ? 3.864   -24.142 -17.071 1.00 63.01  ? 101 ASP A O   1 
ATOM   742  C  CB  . ASP A 1 101 ? 6.699   -22.962 -16.444 1.00 57.77  ? 101 ASP A CB  1 
ATOM   743  C  CG  . ASP A 1 101 ? 6.731   -21.768 -15.509 1.00 65.06  ? 101 ASP A CG  1 
ATOM   744  O  OD1 . ASP A 1 101 ? 7.513   -21.800 -14.527 1.00 69.42  ? 101 ASP A OD1 1 
ATOM   745  O  OD2 . ASP A 1 101 ? 5.986   -20.799 -15.761 1.00 62.46  ? 101 ASP A OD2 1 
ATOM   746  N  N   . SER A 1 102 ? 3.810   -23.521 -14.891 1.00 59.35  ? 102 SER A N   1 
ATOM   747  C  CA  . SER A 1 102 ? 2.371   -23.278 -14.803 1.00 59.83  ? 102 SER A CA  1 
ATOM   748  C  C   . SER A 1 102 ? 1.995   -21.782 -14.757 1.00 60.92  ? 102 SER A C   1 
ATOM   749  O  O   . SER A 1 102 ? 0.817   -21.458 -14.568 1.00 61.75  ? 102 SER A O   1 
ATOM   750  C  CB  . SER A 1 102 ? 1.785   -24.036 -13.616 1.00 66.76  ? 102 SER A CB  1 
ATOM   751  O  OG  . SER A 1 102 ? 2.035   -25.428 -13.732 1.00 77.84  ? 102 SER A OG  1 
ATOM   752  N  N   . VAL A 1 103 ? 2.984   -20.876 -14.951 1.00 54.50  ? 103 VAL A N   1 
ATOM   753  C  CA  . VAL A 1 103 ? 2.761   -19.422 -14.965 1.00 52.86  ? 103 VAL A CA  1 
ATOM   754  C  C   . VAL A 1 103 ? 2.714   -18.911 -16.414 1.00 55.93  ? 103 VAL A C   1 
ATOM   755  O  O   . VAL A 1 103 ? 1.794   -18.167 -16.771 1.00 56.79  ? 103 VAL A O   1 
ATOM   756  C  CB  . VAL A 1 103 ? 3.736   -18.638 -14.056 1.00 55.52  ? 103 VAL A CB  1 
ATOM   757  C  CG1 . VAL A 1 103 ? 3.533   -17.130 -14.194 1.00 54.34  ? 103 VAL A CG1 1 
ATOM   758  C  CG2 . VAL A 1 103 ? 3.574   -19.061 -12.592 1.00 57.07  ? 103 VAL A CG2 1 
ATOM   759  N  N   . ILE A 1 104 ? 3.666   -19.348 -17.256 1.00 50.76  ? 104 ILE A N   1 
ATOM   760  C  CA  . ILE A 1 104 ? 3.640   -19.015 -18.686 1.00 49.52  ? 104 ILE A CA  1 
ATOM   761  C  C   . ILE A 1 104 ? 2.474   -19.774 -19.318 1.00 53.58  ? 104 ILE A C   1 
ATOM   762  O  O   . ILE A 1 104 ? 1.997   -20.765 -18.755 1.00 53.74  ? 104 ILE A O   1 
ATOM   763  C  CB  . ILE A 1 104 ? 4.978   -19.305 -19.447 1.00 51.10  ? 104 ILE A CB  1 
ATOM   764  C  CG1 . ILE A 1 104 ? 5.477   -20.755 -19.221 1.00 51.98  ? 104 ILE A CG1 1 
ATOM   765  C  CG2 . ILE A 1 104 ? 6.036   -18.266 -19.111 1.00 50.81  ? 104 ILE A CG2 1 
ATOM   766  C  CD1 . ILE A 1 104 ? 6.450   -21.311 -20.268 1.00 51.74  ? 104 ILE A CD1 1 
ATOM   767  N  N   . SER A 1 105 ? 2.018   -19.307 -20.479 1.00 49.43  ? 105 SER A N   1 
ATOM   768  C  CA  . SER A 1 105 ? 0.934   -19.940 -21.214 1.00 49.61  ? 105 SER A CA  1 
ATOM   769  C  C   . SER A 1 105 ? 1.117   -19.684 -22.698 1.00 52.78  ? 105 SER A C   1 
ATOM   770  O  O   . SER A 1 105 ? 1.868   -18.785 -23.076 1.00 49.70  ? 105 SER A O   1 
ATOM   771  C  CB  . SER A 1 105 ? -0.415  -19.408 -20.737 1.00 52.15  ? 105 SER A CB  1 
ATOM   772  O  OG  . SER A 1 105 ? -1.476  -20.173 -21.282 1.00 57.41  ? 105 SER A OG  1 
ATOM   773  N  N   . LEU A 1 106 ? 0.456   -20.494 -23.538 1.00 52.66  ? 106 LEU A N   1 
ATOM   774  C  CA  . LEU A 1 106 ? 0.478   -20.322 -24.987 1.00 52.91  ? 106 LEU A CA  1 
ATOM   775  C  C   . LEU A 1 106 ? -0.890  -19.759 -25.445 1.00 60.08  ? 106 LEU A C   1 
ATOM   776  O  O   . LEU A 1 106 ? -1.230  -19.830 -26.625 1.00 60.31  ? 106 LEU A O   1 
ATOM   777  C  CB  . LEU A 1 106 ? 0.863   -21.632 -25.728 1.00 53.77  ? 106 LEU A CB  1 
ATOM   778  C  CG  . LEU A 1 106 ? 2.221   -22.303 -25.375 1.00 57.61  ? 106 LEU A CG  1 
ATOM   779  C  CD1 . LEU A 1 106 ? 2.452   -23.548 -26.216 1.00 58.75  ? 106 LEU A CD1 1 
ATOM   780  C  CD2 . LEU A 1 106 ? 3.407   -21.350 -25.545 1.00 56.85  ? 106 LEU A CD2 1 
ATOM   781  N  N   . SER A 1 107 ? -1.654  -19.167 -24.488 1.00 58.90  ? 107 SER A N   1 
ATOM   782  C  CA  . SER A 1 107 ? -2.969  -18.527 -24.670 1.00 60.65  ? 107 SER A CA  1 
ATOM   783  C  C   . SER A 1 107 ? -3.270  -17.625 -23.457 1.00 64.22  ? 107 SER A C   1 
ATOM   784  O  O   . SER A 1 107 ? -2.568  -17.711 -22.453 1.00 63.49  ? 107 SER A O   1 
ATOM   785  C  CB  . SER A 1 107 ? -4.070  -19.577 -24.837 1.00 67.48  ? 107 SER A CB  1 
ATOM   786  O  OG  . SER A 1 107 ? -4.170  -20.420 -23.699 1.00 77.88  ? 107 SER A OG  1 
ATOM   787  N  N   . GLY A 1 108 ? -4.288  -16.769 -23.565 1.00 61.89  ? 108 GLY A N   1 
ATOM   788  C  CA  . GLY A 1 108 ? -4.712  -15.884 -22.478 1.00 62.06  ? 108 GLY A CA  1 
ATOM   789  C  C   . GLY A 1 108 ? -3.795  -14.715 -22.171 1.00 62.33  ? 108 GLY A C   1 
ATOM   790  O  O   . GLY A 1 108 ? -2.901  -14.396 -22.959 1.00 59.90  ? 108 GLY A O   1 
ATOM   791  N  N   . ASP A 1 109 ? -4.021  -14.058 -21.016 1.00 58.76  ? 109 ASP A N   1 
ATOM   792  C  CA  . ASP A 1 109 ? -3.247  -12.892 -20.567 1.00 57.60  ? 109 ASP A CA  1 
ATOM   793  C  C   . ASP A 1 109 ? -1.737  -13.129 -20.442 1.00 56.84  ? 109 ASP A C   1 
ATOM   794  O  O   . ASP A 1 109 ? -0.960  -12.188 -20.611 1.00 55.32  ? 109 ASP A O   1 
ATOM   795  C  CB  . ASP A 1 109 ? -3.794  -12.331 -19.249 1.00 61.17  ? 109 ASP A CB  1 
ATOM   796  C  CG  . ASP A 1 109 ? -5.168  -11.679 -19.337 1.00 76.25  ? 109 ASP A CG  1 
ATOM   797  O  OD1 . ASP A 1 109 ? -5.494  -11.103 -20.409 1.00 78.28  ? 109 ASP A OD1 1 
ATOM   798  O  OD2 . ASP A 1 109 ? -5.904  -11.721 -18.333 1.00 79.76  ? 109 ASP A OD2 1 
ATOM   799  N  N   . HIS A 1 110 ? -1.333  -14.368 -20.122 1.00 52.10  ? 110 HIS A N   1 
ATOM   800  C  CA  . HIS A 1 110 ? 0.068   -14.737 -19.932 1.00 50.53  ? 110 HIS A CA  1 
ATOM   801  C  C   . HIS A 1 110 ? 0.694   -15.399 -21.175 1.00 52.70  ? 110 HIS A C   1 
ATOM   802  O  O   . HIS A 1 110 ? 1.756   -16.019 -21.051 1.00 50.44  ? 110 HIS A O   1 
ATOM   803  C  CB  . HIS A 1 110 ? 0.228   -15.630 -18.682 1.00 51.80  ? 110 HIS A CB  1 
ATOM   804  C  CG  . HIS A 1 110 ? -0.115  -14.966 -17.380 1.00 56.53  ? 110 HIS A CG  1 
ATOM   805  N  ND1 . HIS A 1 110 ? -0.058  -15.663 -16.188 1.00 59.33  ? 110 HIS A ND1 1 
ATOM   806  C  CD2 . HIS A 1 110 ? -0.528  -13.699 -17.123 1.00 59.03  ? 110 HIS A CD2 1 
ATOM   807  C  CE1 . HIS A 1 110 ? -0.433  -14.807 -15.249 1.00 59.61  ? 110 HIS A CE1 1 
ATOM   808  N  NE2 . HIS A 1 110 ? -0.722  -13.612 -15.764 1.00 59.81  ? 110 HIS A NE2 1 
ATOM   809  N  N   . CYS A 1 111 ? 0.054   -15.249 -22.368 1.00 49.51  ? 111 CYS A N   1 
ATOM   810  C  CA  . CYS A 1 111 ? 0.568   -15.830 -23.610 1.00 48.89  ? 111 CYS A CA  1 
ATOM   811  C  C   . CYS A 1 111 ? 1.950   -15.294 -23.990 1.00 49.40  ? 111 CYS A C   1 
ATOM   812  O  O   . CYS A 1 111 ? 2.168   -14.084 -23.978 1.00 49.07  ? 111 CYS A O   1 
ATOM   813  C  CB  . CYS A 1 111 ? -0.424  -15.691 -24.760 1.00 50.66  ? 111 CYS A CB  1 
ATOM   814  S  SG  . CYS A 1 111 ? 0.096   -16.539 -26.269 1.00 54.27  ? 111 CYS A SG  1 
ATOM   815  N  N   . ILE A 1 112 ? 2.883   -16.199 -24.300 1.00 44.34  ? 112 ILE A N   1 
ATOM   816  C  CA  . ILE A 1 112 ? 4.266   -15.825 -24.631 1.00 42.80  ? 112 ILE A CA  1 
ATOM   817  C  C   . ILE A 1 112 ? 4.564   -15.925 -26.129 1.00 45.34  ? 112 ILE A C   1 
ATOM   818  O  O   . ILE A 1 112 ? 5.683   -15.629 -26.544 1.00 43.69  ? 112 ILE A O   1 
ATOM   819  C  CB  . ILE A 1 112 ? 5.302   -16.598 -23.772 1.00 45.54  ? 112 ILE A CB  1 
ATOM   820  C  CG1 . ILE A 1 112 ? 5.301   -18.123 -24.097 1.00 46.24  ? 112 ILE A CG1 1 
ATOM   821  C  CG2 . ILE A 1 112 ? 5.089   -16.295 -22.272 1.00 47.32  ? 112 ILE A CG2 1 
ATOM   822  C  CD1 . ILE A 1 112 ? 6.359   -18.951 -23.393 1.00 48.50  ? 112 ILE A CD1 1 
ATOM   823  N  N   . ILE A 1 113 ? 3.566   -16.325 -26.939 1.00 43.15  ? 113 ILE A N   1 
ATOM   824  C  CA  . ILE A 1 113 ? 3.726   -16.396 -28.390 1.00 42.79  ? 113 ILE A CA  1 
ATOM   825  C  C   . ILE A 1 113 ? 3.928   -14.976 -28.898 1.00 45.01  ? 113 ILE A C   1 
ATOM   826  O  O   . ILE A 1 113 ? 3.230   -14.059 -28.471 1.00 43.80  ? 113 ILE A O   1 
ATOM   827  C  CB  . ILE A 1 113 ? 2.542   -17.151 -29.061 1.00 47.95  ? 113 ILE A CB  1 
ATOM   828  C  CG1 . ILE A 1 113 ? 2.623   -18.662 -28.719 1.00 49.29  ? 113 ILE A CG1 1 
ATOM   829  C  CG2 . ILE A 1 113 ? 2.504   -16.920 -30.603 1.00 48.92  ? 113 ILE A CG2 1 
ATOM   830  C  CD1 . ILE A 1 113 ? 1.324   -19.446 -28.874 1.00 57.34  ? 113 ILE A CD1 1 
ATOM   831  N  N   . GLY A 1 114 ? 4.946   -14.804 -29.732 1.00 42.58  ? 114 GLY A N   1 
ATOM   832  C  CA  . GLY A 1 114 ? 5.296   -13.513 -30.299 1.00 42.42  ? 114 GLY A CA  1 
ATOM   833  C  C   . GLY A 1 114 ? 6.152   -12.667 -29.385 1.00 44.32  ? 114 GLY A C   1 
ATOM   834  O  O   . GLY A 1 114 ? 6.436   -11.522 -29.719 1.00 45.21  ? 114 GLY A O   1 
ATOM   835  N  N   . ARG A 1 115 ? 6.525   -13.196 -28.207 1.00 39.42  ? 115 ARG A N   1 
ATOM   836  C  CA  . ARG A 1 115 ? 7.425   -12.525 -27.275 1.00 39.55  ? 115 ARG A CA  1 
ATOM   837  C  C   . ARG A 1 115 ? 8.824   -13.116 -27.504 1.00 45.95  ? 115 ARG A C   1 
ATOM   838  O  O   . ARG A 1 115 ? 8.994   -13.912 -28.439 1.00 45.56  ? 115 ARG A O   1 
ATOM   839  C  CB  . ARG A 1 115 ? 6.926   -12.633 -25.812 1.00 40.21  ? 115 ARG A CB  1 
ATOM   840  C  CG  . ARG A 1 115 ? 5.542   -11.991 -25.675 1.00 44.06  ? 115 ARG A CG  1 
ATOM   841  C  CD  . ARG A 1 115 ? 5.107   -11.737 -24.256 1.00 46.50  ? 115 ARG A CD  1 
ATOM   842  N  NE  . ARG A 1 115 ? 3.679   -11.408 -24.202 1.00 48.12  ? 115 ARG A NE  1 
ATOM   843  C  CZ  . ARG A 1 115 ? 3.169   -10.188 -24.354 1.00 59.32  ? 115 ARG A CZ  1 
ATOM   844  N  NH1 . ARG A 1 115 ? 3.964   -9.151  -24.573 1.00 43.26  ? 115 ARG A NH1 1 
ATOM   845  N  NH2 . ARG A 1 115 ? 1.861   -9.991  -24.251 1.00 53.38  ? 115 ARG A NH2 1 
ATOM   846  N  N   . THR A 1 116 ? 9.837   -12.684 -26.741 1.00 43.28  ? 116 THR A N   1 
ATOM   847  C  CA  . THR A 1 116 ? 11.203  -13.173 -26.974 1.00 43.06  ? 116 THR A CA  1 
ATOM   848  C  C   . THR A 1 116 ? 11.736  -14.005 -25.817 1.00 45.22  ? 116 THR A C   1 
ATOM   849  O  O   . THR A 1 116 ? 11.659  -13.572 -24.675 1.00 45.80  ? 116 THR A O   1 
ATOM   850  C  CB  . THR A 1 116 ? 12.132  -11.985 -27.317 1.00 48.86  ? 116 THR A CB  1 
ATOM   851  O  OG1 . THR A 1 116 ? 11.724  -11.417 -28.552 1.00 44.13  ? 116 THR A OG1 1 
ATOM   852  C  CG2 . THR A 1 116 ? 13.601  -12.373 -27.436 1.00 47.66  ? 116 THR A CG2 1 
ATOM   853  N  N   . LEU A 1 117 ? 12.296  -15.186 -26.116 1.00 41.59  ? 117 LEU A N   1 
ATOM   854  C  CA  . LEU A 1 117 ? 12.987  -15.991 -25.108 1.00 42.64  ? 117 LEU A CA  1 
ATOM   855  C  C   . LEU A 1 117 ? 14.475  -15.585 -25.174 1.00 45.85  ? 117 LEU A C   1 
ATOM   856  O  O   . LEU A 1 117 ? 15.034  -15.481 -26.272 1.00 43.96  ? 117 LEU A O   1 
ATOM   857  C  CB  . LEU A 1 117 ? 12.798  -17.494 -25.380 1.00 43.58  ? 117 LEU A CB  1 
ATOM   858  C  CG  . LEU A 1 117 ? 13.571  -18.481 -24.489 1.00 47.95  ? 117 LEU A CG  1 
ATOM   859  C  CD1 . LEU A 1 117 ? 12.975  -18.567 -23.062 1.00 47.76  ? 117 LEU A CD1 1 
ATOM   860  C  CD2 . LEU A 1 117 ? 13.570  -19.843 -25.112 1.00 49.09  ? 117 LEU A CD2 1 
ATOM   861  N  N   . VAL A 1 118 ? 15.093  -15.297 -24.012 1.00 42.24  ? 118 VAL A N   1 
ATOM   862  C  CA  . VAL A 1 118 ? 16.483  -14.847 -23.914 1.00 43.32  ? 118 VAL A CA  1 
ATOM   863  C  C   . VAL A 1 118 ? 17.296  -15.734 -22.961 1.00 47.50  ? 118 VAL A C   1 
ATOM   864  O  O   . VAL A 1 118 ? 16.857  -15.991 -21.831 1.00 46.87  ? 118 VAL A O   1 
ATOM   865  C  CB  . VAL A 1 118 ? 16.580  -13.349 -23.458 1.00 47.67  ? 118 VAL A CB  1 
ATOM   866  C  CG1 . VAL A 1 118 ? 18.032  -12.917 -23.182 1.00 48.46  ? 118 VAL A CG1 1 
ATOM   867  C  CG2 . VAL A 1 118 ? 15.933  -12.406 -24.458 1.00 46.55  ? 118 VAL A CG2 1 
ATOM   868  N  N   . VAL A 1 119 ? 18.505  -16.151 -23.408 1.00 44.14  ? 119 VAL A N   1 
ATOM   869  C  CA  . VAL A 1 119 ? 19.489  -16.856 -22.575 1.00 44.85  ? 119 VAL A CA  1 
ATOM   870  C  C   . VAL A 1 119 ? 20.560  -15.815 -22.222 1.00 48.57  ? 119 VAL A C   1 
ATOM   871  O  O   . VAL A 1 119 ? 21.131  -15.174 -23.112 1.00 47.73  ? 119 VAL A O   1 
ATOM   872  C  CB  . VAL A 1 119 ? 20.036  -18.203 -23.141 1.00 49.38  ? 119 VAL A CB  1 
ATOM   873  C  CG1 . VAL A 1 119 ? 20.714  -18.037 -24.504 1.00 49.34  ? 119 VAL A CG1 1 
ATOM   874  C  CG2 . VAL A 1 119 ? 20.969  -18.894 -22.137 1.00 50.30  ? 119 VAL A CG2 1 
ATOM   875  N  N   . HIS A 1 120 ? 20.760  -15.592 -20.917 1.00 46.83  ? 120 HIS A N   1 
ATOM   876  C  CA  . HIS A 1 120 ? 21.667  -14.576 -20.386 1.00 48.58  ? 120 HIS A CA  1 
ATOM   877  C  C   . HIS A 1 120 ? 23.108  -15.022 -20.100 1.00 53.54  ? 120 HIS A C   1 
ATOM   878  O  O   . HIS A 1 120 ? 23.402  -16.209 -19.990 1.00 53.35  ? 120 HIS A O   1 
ATOM   879  C  CB  . HIS A 1 120 ? 21.065  -13.947 -19.130 1.00 49.26  ? 120 HIS A CB  1 
ATOM   880  C  CG  . HIS A 1 120 ? 19.874  -13.093 -19.416 1.00 51.28  ? 120 HIS A CG  1 
ATOM   881  N  ND1 . HIS A 1 120 ? 20.005  -11.744 -19.682 1.00 53.32  ? 120 HIS A ND1 1 
ATOM   882  C  CD2 . HIS A 1 120 ? 18.565  -13.430 -19.481 1.00 52.19  ? 120 HIS A CD2 1 
ATOM   883  C  CE1 . HIS A 1 120 ? 18.773  -11.297 -19.881 1.00 51.95  ? 120 HIS A CE1 1 
ATOM   884  N  NE2 . HIS A 1 120 ? 17.873  -12.278 -19.780 1.00 51.36  ? 120 HIS A NE2 1 
ATOM   885  N  N   . GLU A 1 121 ? 23.994  -14.020 -19.974 1.00 51.41  ? 121 GLU A N   1 
ATOM   886  C  CA  . GLU A 1 121 ? 25.434  -14.109 -19.734 1.00 53.56  ? 121 GLU A CA  1 
ATOM   887  C  C   . GLU A 1 121 ? 25.815  -14.811 -18.428 1.00 58.04  ? 121 GLU A C   1 
ATOM   888  O  O   . GLU A 1 121 ? 26.748  -15.621 -18.430 1.00 57.95  ? 121 GLU A O   1 
ATOM   889  C  CB  . GLU A 1 121 ? 26.028  -12.686 -19.774 1.00 56.45  ? 121 GLU A CB  1 
ATOM   890  C  CG  . GLU A 1 121 ? 27.532  -12.572 -19.520 1.00 67.18  ? 121 GLU A CG  1 
ATOM   891  C  CD  . GLU A 1 121 ? 28.006  -11.261 -18.917 1.00 88.87  ? 121 GLU A CD  1 
ATOM   892  O  OE1 . GLU A 1 121 ? 29.225  -11.147 -18.651 1.00 101.03 ? 121 GLU A OE1 1 
ATOM   893  O  OE2 . GLU A 1 121 ? 27.167  -10.357 -18.692 1.00 70.23  ? 121 GLU A OE2 1 
ATOM   894  N  N   . LYS A 1 122 ? 25.125  -14.468 -17.314 1.00 55.55  ? 122 LYS A N   1 
ATOM   895  C  CA  . LYS A 1 122 ? 25.418  -14.981 -15.969 1.00 57.42  ? 122 LYS A CA  1 
ATOM   896  C  C   . LYS A 1 122 ? 24.200  -15.663 -15.356 1.00 59.62  ? 122 LYS A C   1 
ATOM   897  O  O   . LYS A 1 122 ? 23.093  -15.585 -15.902 1.00 57.57  ? 122 LYS A O   1 
ATOM   898  C  CB  . LYS A 1 122 ? 25.863  -13.833 -15.031 1.00 61.46  ? 122 LYS A CB  1 
ATOM   899  C  CG  . LYS A 1 122 ? 27.159  -13.126 -15.426 1.00 75.05  ? 122 LYS A CG  1 
ATOM   900  C  CD  . LYS A 1 122 ? 26.978  -11.603 -15.516 1.00 83.59  ? 122 LYS A CD  1 
ATOM   901  C  CE  . LYS A 1 122 ? 27.105  -10.870 -14.199 1.00 91.93  ? 122 LYS A CE  1 
ATOM   902  N  NZ  . LYS A 1 122 ? 28.527  -10.692 -13.803 1.00 108.40 ? 122 LYS A NZ  1 
ATOM   903  N  N   . ALA A 1 123 ? 24.405  -16.314 -14.205 1.00 55.97  ? 123 ALA A N   1 
ATOM   904  C  CA  . ALA A 1 123 ? 23.339  -16.980 -13.468 1.00 55.65  ? 123 ALA A CA  1 
ATOM   905  C  C   . ALA A 1 123 ? 22.284  -15.983 -12.992 1.00 57.52  ? 123 ALA A C   1 
ATOM   906  O  O   . ALA A 1 123 ? 22.607  -14.855 -12.618 1.00 57.69  ? 123 ALA A O   1 
ATOM   907  C  CB  . ALA A 1 123 ? 23.918  -17.705 -12.263 1.00 58.66  ? 123 ALA A CB  1 
ATOM   908  N  N   . ASP A 1 124 ? 21.019  -16.401 -13.019 1.00 52.39  ? 124 ASP A N   1 
ATOM   909  C  CA  . ASP A 1 124 ? 19.916  -15.650 -12.442 1.00 50.52  ? 124 ASP A CA  1 
ATOM   910  C  C   . ASP A 1 124 ? 19.983  -15.940 -10.904 1.00 53.84  ? 124 ASP A C   1 
ATOM   911  O  O   . ASP A 1 124 ? 19.931  -17.106 -10.499 1.00 52.54  ? 124 ASP A O   1 
ATOM   912  C  CB  . ASP A 1 124 ? 18.585  -16.123 -13.060 1.00 50.59  ? 124 ASP A CB  1 
ATOM   913  C  CG  . ASP A 1 124 ? 17.330  -15.482 -12.499 1.00 56.09  ? 124 ASP A CG  1 
ATOM   914  O  OD1 . ASP A 1 124 ? 17.448  -14.657 -11.566 1.00 55.19  ? 124 ASP A OD1 1 
ATOM   915  O  OD2 . ASP A 1 124 ? 16.231  -15.808 -12.993 1.00 59.59  ? 124 ASP A OD2 1 
ATOM   916  N  N   . ASP A 1 125 ? 20.118  -14.890 -10.062 1.00 51.83  ? 125 ASP A N   1 
ATOM   917  C  CA  . ASP A 1 125 ? 20.223  -15.067 -8.592  1.00 54.05  ? 125 ASP A CA  1 
ATOM   918  C  C   . ASP A 1 125 ? 18.854  -15.308 -7.923  1.00 57.94  ? 125 ASP A C   1 
ATOM   919  O  O   . ASP A 1 125 ? 18.785  -15.477 -6.699  1.00 57.98  ? 125 ASP A O   1 
ATOM   920  C  CB  . ASP A 1 125 ? 21.011  -13.919 -7.906  1.00 56.27  ? 125 ASP A CB  1 
ATOM   921  C  CG  . ASP A 1 125 ? 20.401  -12.527 -8.003  1.00 60.70  ? 125 ASP A CG  1 
ATOM   922  O  OD1 . ASP A 1 125 ? 19.158  -12.421 -8.087  1.00 58.86  ? 125 ASP A OD1 1 
ATOM   923  O  OD2 . ASP A 1 125 ? 21.165  -11.545 -7.979  1.00 66.38  ? 125 ASP A OD2 1 
ATOM   924  N  N   . LEU A 1 126 ? 17.773  -15.325 -8.745  1.00 54.68  ? 126 LEU A N   1 
ATOM   925  C  CA  . LEU A 1 126 ? 16.371  -15.610 -8.392  1.00 54.94  ? 126 LEU A CA  1 
ATOM   926  C  C   . LEU A 1 126 ? 15.774  -14.653 -7.332  1.00 58.98  ? 126 LEU A C   1 
ATOM   927  O  O   . LEU A 1 126 ? 14.890  -15.048 -6.568  1.00 59.74  ? 126 LEU A O   1 
ATOM   928  C  CB  . LEU A 1 126 ? 16.191  -17.101 -7.969  1.00 55.88  ? 126 LEU A CB  1 
ATOM   929  C  CG  . LEU A 1 126 ? 16.959  -18.168 -8.790  1.00 60.41  ? 126 LEU A CG  1 
ATOM   930  C  CD1 . LEU A 1 126 ? 17.118  -19.452 -8.010  1.00 62.21  ? 126 LEU A CD1 1 
ATOM   931  C  CD2 . LEU A 1 126 ? 16.322  -18.411 -10.159 1.00 58.74  ? 126 LEU A CD2 1 
ATOM   932  N  N   . GLY A 1 127 ? 16.239  -13.404 -7.329  1.00 55.61  ? 127 GLY A N   1 
ATOM   933  C  CA  . GLY A 1 127 ? 15.803  -12.377 -6.384  1.00 56.88  ? 127 GLY A CA  1 
ATOM   934  C  C   . GLY A 1 127 ? 16.475  -12.443 -5.020  1.00 62.14  ? 127 GLY A C   1 
ATOM   935  O  O   . GLY A 1 127 ? 16.148  -11.646 -4.136  1.00 63.93  ? 127 GLY A O   1 
ATOM   936  N  N   . LYS A 1 128 ? 17.451  -13.363 -4.847  1.00 57.87  ? 128 LYS A N   1 
ATOM   937  C  CA  . LYS A 1 128 ? 18.181  -13.582 -3.590  1.00 59.05  ? 128 LYS A CA  1 
ATOM   938  C  C   . LYS A 1 128 ? 19.643  -13.109 -3.661  1.00 63.12  ? 128 LYS A C   1 
ATOM   939  O  O   . LYS A 1 128 ? 20.511  -13.654 -2.975  1.00 63.88  ? 128 LYS A O   1 
ATOM   940  C  CB  . LYS A 1 128 ? 18.097  -15.071 -3.176  1.00 61.41  ? 128 LYS A CB  1 
ATOM   941  C  CG  . LYS A 1 128 ? 16.680  -15.659 -3.095  1.00 66.34  ? 128 LYS A CG  1 
ATOM   942  C  CD  . LYS A 1 128 ? 15.906  -15.252 -1.854  1.00 75.29  ? 128 LYS A CD  1 
ATOM   943  C  CE  . LYS A 1 128 ? 14.533  -15.888 -1.811  1.00 80.64  ? 128 LYS A CE  1 
ATOM   944  N  NZ  . LYS A 1 128 ? 13.494  -15.038 -2.452  1.00 81.53  ? 128 LYS A NZ  1 
ATOM   945  N  N   . GLY A 1 129 ? 19.895  -12.102 -4.493  1.00 59.27  ? 129 GLY A N   1 
ATOM   946  C  CA  . GLY A 1 129 ? 21.222  -11.540 -4.705  1.00 60.14  ? 129 GLY A CA  1 
ATOM   947  C  C   . GLY A 1 129 ? 21.658  -10.468 -3.732  1.00 66.70  ? 129 GLY A C   1 
ATOM   948  O  O   . GLY A 1 129 ? 22.837  -10.135 -3.693  1.00 68.62  ? 129 GLY A O   1 
ATOM   949  N  N   . GLY A 1 130 ? 20.720  -9.907  -2.977  1.00 63.36  ? 130 GLY A N   1 
ATOM   950  C  CA  . GLY A 1 130 ? 21.014  -8.894  -1.971  1.00 65.49  ? 130 GLY A CA  1 
ATOM   951  C  C   . GLY A 1 130 ? 21.158  -7.455  -2.415  1.00 71.04  ? 130 GLY A C   1 
ATOM   952  O  O   . GLY A 1 130 ? 21.658  -6.634  -1.644  1.00 72.38  ? 130 GLY A O   1 
ATOM   953  N  N   . ASN A 1 131 ? 20.730  -7.126  -3.643  1.00 68.84  ? 131 ASN A N   1 
ATOM   954  C  CA  . ASN A 1 131 ? 20.789  -5.750  -4.141  1.00 69.67  ? 131 ASN A CA  1 
ATOM   955  C  C   . ASN A 1 131 ? 19.526  -5.367  -4.906  1.00 71.99  ? 131 ASN A C   1 
ATOM   956  O  O   . ASN A 1 131 ? 18.648  -6.211  -5.109  1.00 68.73  ? 131 ASN A O   1 
ATOM   957  C  CB  . ASN A 1 131 ? 22.076  -5.450  -4.927  1.00 68.34  ? 131 ASN A CB  1 
ATOM   958  C  CG  . ASN A 1 131 ? 22.416  -6.346  -6.092  1.00 86.96  ? 131 ASN A CG  1 
ATOM   959  O  OD1 . ASN A 1 131 ? 21.595  -7.106  -6.625  1.00 80.47  ? 131 ASN A OD1 1 
ATOM   960  N  ND2 . ASN A 1 131 ? 23.657  -6.237  -6.535  1.00 74.83  ? 131 ASN A ND2 1 
ATOM   961  N  N   . GLU A 1 132 ? 19.403  -4.073  -5.262  1.00 71.12  ? 132 GLU A N   1 
ATOM   962  C  CA  . GLU A 1 132 ? 18.248  -3.533  -5.979  1.00 70.53  ? 132 GLU A CA  1 
ATOM   963  C  C   . GLU A 1 132 ? 18.050  -4.201  -7.339  1.00 70.36  ? 132 GLU A C   1 
ATOM   964  O  O   . GLU A 1 132 ? 16.911  -4.452  -7.717  1.00 68.68  ? 132 GLU A O   1 
ATOM   965  C  CB  . GLU A 1 132 ? 18.365  -2.006  -6.131  1.00 74.62  ? 132 GLU A CB  1 
ATOM   966  C  CG  . GLU A 1 132 ? 17.035  -1.304  -6.376  1.00 88.91  ? 132 GLU A CG  1 
ATOM   967  C  CD  . GLU A 1 132 ? 17.092  0.113   -6.921  1.00 113.57 ? 132 GLU A CD  1 
ATOM   968  O  OE1 . GLU A 1 132 ? 16.101  0.530   -7.563  1.00 104.05 ? 132 GLU A OE1 1 
ATOM   969  O  OE2 . GLU A 1 132 ? 18.113  0.808   -6.709  1.00 112.11 ? 132 GLU A OE2 1 
ATOM   970  N  N   . GLU A 1 133 ? 19.146  -4.521  -8.051  1.00 66.20  ? 133 GLU A N   1 
ATOM   971  C  CA  . GLU A 1 133 ? 19.076  -5.148  -9.382  1.00 63.69  ? 133 GLU A CA  1 
ATOM   972  C  C   . GLU A 1 133 ? 18.561  -6.599  -9.351  1.00 64.52  ? 133 GLU A C   1 
ATOM   973  O  O   . GLU A 1 133 ? 17.943  -7.052  -10.312 1.00 61.78  ? 133 GLU A O   1 
ATOM   974  C  CB  . GLU A 1 133 ? 20.428  -5.042  -10.118 1.00 65.50  ? 133 GLU A CB  1 
ATOM   975  C  CG  . GLU A 1 133 ? 20.339  -5.224  -11.630 1.00 73.55  ? 133 GLU A CG  1 
ATOM   976  C  CD  . GLU A 1 133 ? 19.360  -4.333  -12.374 1.00 93.97  ? 133 GLU A CD  1 
ATOM   977  O  OE1 . GLU A 1 133 ? 19.356  -3.104  -12.132 1.00 89.25  ? 133 GLU A OE1 1 
ATOM   978  O  OE2 . GLU A 1 133 ? 18.595  -4.869  -13.207 1.00 88.04  ? 133 GLU A OE2 1 
ATOM   979  N  N   . SER A 1 134 ? 18.801  -7.302  -8.240  1.00 61.50  ? 134 SER A N   1 
ATOM   980  C  CA  . SER A 1 134 ? 18.389  -8.687  -8.004  1.00 59.56  ? 134 SER A CA  1 
ATOM   981  C  C   . SER A 1 134 ? 16.867  -8.880  -8.100  1.00 62.04  ? 134 SER A C   1 
ATOM   982  O  O   . SER A 1 134 ? 16.411  -9.878  -8.662  1.00 59.69  ? 134 SER A O   1 
ATOM   983  C  CB  . SER A 1 134 ? 18.894  -9.141  -6.640  1.00 62.58  ? 134 SER A CB  1 
ATOM   984  O  OG  . SER A 1 134 ? 18.556  -10.488 -6.381  1.00 67.05  ? 134 SER A OG  1 
ATOM   985  N  N   . THR A 1 135 ? 16.099  -7.900  -7.587  1.00 59.39  ? 135 THR A N   1 
ATOM   986  C  CA  . THR A 1 135 ? 14.636  -7.893  -7.551  1.00 59.23  ? 135 THR A CA  1 
ATOM   987  C  C   . THR A 1 135 ? 14.026  -7.383  -8.886  1.00 63.70  ? 135 THR A C   1 
ATOM   988  O  O   . THR A 1 135 ? 12.802  -7.411  -9.065  1.00 61.84  ? 135 THR A O   1 
ATOM   989  C  CB  . THR A 1 135 ? 14.183  -7.123  -6.284  1.00 73.62  ? 135 THR A CB  1 
ATOM   990  O  OG1 . THR A 1 135 ? 13.019  -7.732  -5.731  1.00 75.29  ? 135 THR A OG1 1 
ATOM   991  C  CG2 . THR A 1 135 ? 13.985  -5.619  -6.513  1.00 74.46  ? 135 THR A CG2 1 
ATOM   992  N  N   . LYS A 1 136 ? 14.892  -6.967  -9.828  1.00 61.07  ? 136 LYS A N   1 
ATOM   993  C  CA  . LYS A 1 136 ? 14.510  -6.461  -11.139 1.00 60.35  ? 136 LYS A CA  1 
ATOM   994  C  C   . LYS A 1 136 ? 14.828  -7.457  -12.250 1.00 62.22  ? 136 LYS A C   1 
ATOM   995  O  O   . LYS A 1 136 ? 13.925  -7.830  -12.998 1.00 61.32  ? 136 LYS A O   1 
ATOM   996  C  CB  . LYS A 1 136 ? 15.181  -5.105  -11.422 1.00 64.75  ? 136 LYS A CB  1 
ATOM   997  C  CG  . LYS A 1 136 ? 14.707  -3.962  -10.527 1.00 80.44  ? 136 LYS A CG  1 
ATOM   998  C  CD  . LYS A 1 136 ? 15.535  -2.713  -10.780 1.00 92.96  ? 136 LYS A CD  1 
ATOM   999  C  CE  . LYS A 1 136 ? 14.989  -1.503  -10.069 1.00 106.08 ? 136 LYS A CE  1 
ATOM   1000 N  NZ  . LYS A 1 136 ? 15.848  -0.311  -10.289 1.00 116.83 ? 136 LYS A NZ  1 
ATOM   1001 N  N   . THR A 1 137 ? 16.098  -7.886  -12.368 1.00 58.54  ? 137 THR A N   1 
ATOM   1002 C  CA  . THR A 1 137 ? 16.533  -8.792  -13.443 1.00 57.42  ? 137 THR A CA  1 
ATOM   1003 C  C   . THR A 1 137 ? 17.230  -10.071 -12.961 1.00 60.92  ? 137 THR A C   1 
ATOM   1004 O  O   . THR A 1 137 ? 17.514  -10.956 -13.777 1.00 60.47  ? 137 THR A O   1 
ATOM   1005 C  CB  . THR A 1 137 ? 17.435  -8.042  -14.448 1.00 66.55  ? 137 THR A CB  1 
ATOM   1006 O  OG1 . THR A 1 137 ? 18.599  -7.550  -13.773 1.00 67.84  ? 137 THR A OG1 1 
ATOM   1007 C  CG2 . THR A 1 137 ? 16.707  -6.911  -15.178 1.00 67.01  ? 137 THR A CG2 1 
ATOM   1008 N  N   . GLY A 1 138 ? 17.543  -10.141 -11.672 1.00 56.44  ? 138 GLY A N   1 
ATOM   1009 C  CA  . GLY A 1 138 ? 18.244  -11.284 -11.101 1.00 56.00  ? 138 GLY A CA  1 
ATOM   1010 C  C   . GLY A 1 138 ? 19.733  -11.302 -11.371 1.00 59.47  ? 138 GLY A C   1 
ATOM   1011 O  O   . GLY A 1 138 ? 20.380  -12.334 -11.167 1.00 59.61  ? 138 GLY A O   1 
ATOM   1012 N  N   . ASN A 1 139 ? 20.295  -10.151 -11.819 1.00 54.94  ? 139 ASN A N   1 
ATOM   1013 C  CA  . ASN A 1 139 ? 21.715  -9.955  -12.147 1.00 55.46  ? 139 ASN A CA  1 
ATOM   1014 C  C   . ASN A 1 139 ? 22.216  -10.976 -13.188 1.00 58.20  ? 139 ASN A C   1 
ATOM   1015 O  O   . ASN A 1 139 ? 23.366  -11.408 -13.131 1.00 59.28  ? 139 ASN A O   1 
ATOM   1016 C  CB  . ASN A 1 139 ? 22.593  -9.924  -10.861 1.00 59.70  ? 139 ASN A CB  1 
ATOM   1017 C  CG  . ASN A 1 139 ? 22.340  -8.710  -10.010 1.00 73.14  ? 139 ASN A CG  1 
ATOM   1018 O  OD1 . ASN A 1 139 ? 22.705  -7.586  -10.368 1.00 67.75  ? 139 ASN A OD1 1 
ATOM   1019 N  ND2 . ASN A 1 139 ? 21.719  -8.910  -8.859  1.00 60.66  ? 139 ASN A ND2 1 
ATOM   1020 N  N   . ALA A 1 140 ? 21.338  -11.345 -14.159 1.00 52.68  ? 140 ALA A N   1 
ATOM   1021 C  CA  . ALA A 1 140 ? 21.675  -12.326 -15.190 1.00 52.75  ? 140 ALA A CA  1 
ATOM   1022 C  C   . ALA A 1 140 ? 22.615  -11.773 -16.293 1.00 57.07  ? 140 ALA A C   1 
ATOM   1023 O  O   . ALA A 1 140 ? 23.144  -12.534 -17.110 1.00 55.17  ? 140 ALA A O   1 
ATOM   1024 C  CB  . ALA A 1 140 ? 20.408  -12.927 -15.773 1.00 51.71  ? 140 ALA A CB  1 
ATOM   1025 N  N   . GLY A 1 141 ? 22.868  -10.465 -16.244 1.00 55.24  ? 141 GLY A N   1 
ATOM   1026 C  CA  . GLY A 1 141 ? 23.786  -9.770  -17.139 1.00 55.49  ? 141 GLY A CA  1 
ATOM   1027 C  C   . GLY A 1 141 ? 23.307  -9.618  -18.564 1.00 56.83  ? 141 GLY A C   1 
ATOM   1028 O  O   . GLY A 1 141 ? 22.105  -9.477  -18.813 1.00 53.36  ? 141 GLY A O   1 
ATOM   1029 N  N   . SER A 1 142 ? 24.277  -9.656  -19.506 1.00 54.31  ? 142 SER A N   1 
ATOM   1030 C  CA  . SER A 1 142 ? 24.098  -9.501  -20.947 1.00 53.35  ? 142 SER A CA  1 
ATOM   1031 C  C   . SER A 1 142 ? 23.201  -10.550 -21.606 1.00 53.92  ? 142 SER A C   1 
ATOM   1032 O  O   . SER A 1 142 ? 23.004  -11.639 -21.076 1.00 51.95  ? 142 SER A O   1 
ATOM   1033 C  CB  . SER A 1 142 ? 25.451  -9.451  -21.649 1.00 58.20  ? 142 SER A CB  1 
ATOM   1034 O  OG  . SER A 1 142 ? 25.919  -8.115  -21.660 1.00 72.07  ? 142 SER A OG  1 
ATOM   1035 N  N   . ARG A 1 143 ? 22.679  -10.214 -22.778 1.00 50.81  ? 143 ARG A N   1 
ATOM   1036 C  CA  . ARG A 1 143 ? 21.792  -11.087 -23.543 1.00 49.33  ? 143 ARG A CA  1 
ATOM   1037 C  C   . ARG A 1 143 ? 22.623  -11.821 -24.600 1.00 54.30  ? 143 ARG A C   1 
ATOM   1038 O  O   . ARG A 1 143 ? 22.982  -11.234 -25.627 1.00 55.19  ? 143 ARG A O   1 
ATOM   1039 C  CB  . ARG A 1 143 ? 20.644  -10.259 -24.154 1.00 47.54  ? 143 ARG A CB  1 
ATOM   1040 C  CG  . ARG A 1 143 ? 19.859  -9.492  -23.081 1.00 52.04  ? 143 ARG A CG  1 
ATOM   1041 C  CD  . ARG A 1 143 ? 18.711  -8.658  -23.615 1.00 51.66  ? 143 ARG A CD  1 
ATOM   1042 N  NE  . ARG A 1 143 ? 18.147  -7.836  -22.542 1.00 50.51  ? 143 ARG A NE  1 
ATOM   1043 C  CZ  . ARG A 1 143 ? 17.003  -7.164  -22.617 1.00 61.43  ? 143 ARG A CZ  1 
ATOM   1044 N  NH1 . ARG A 1 143 ? 16.263  -7.221  -23.718 1.00 51.65  ? 143 ARG A NH1 1 
ATOM   1045 N  NH2 . ARG A 1 143 ? 16.577  -6.447  -21.584 1.00 45.99  ? 143 ARG A NH2 1 
ATOM   1046 N  N   . LEU A 1 144 ? 22.974  -13.091 -24.323 1.00 49.75  ? 144 LEU A N   1 
ATOM   1047 C  CA  . LEU A 1 144 ? 23.807  -13.892 -25.234 1.00 49.73  ? 144 LEU A CA  1 
ATOM   1048 C  C   . LEU A 1 144 ? 23.099  -14.251 -26.538 1.00 51.36  ? 144 LEU A C   1 
ATOM   1049 O  O   . LEU A 1 144 ? 23.669  -14.083 -27.630 1.00 50.28  ? 144 LEU A O   1 
ATOM   1050 C  CB  . LEU A 1 144 ? 24.325  -15.168 -24.545 1.00 50.55  ? 144 LEU A CB  1 
ATOM   1051 C  CG  . LEU A 1 144 ? 25.279  -15.000 -23.342 1.00 56.66  ? 144 LEU A CG  1 
ATOM   1052 C  CD1 . LEU A 1 144 ? 25.726  -16.357 -22.818 1.00 57.84  ? 144 LEU A CD1 1 
ATOM   1053 C  CD2 . LEU A 1 144 ? 26.516  -14.177 -23.696 1.00 60.13  ? 144 LEU A CD2 1 
ATOM   1054 N  N   . ALA A 1 145 ? 21.871  -14.774 -26.420 1.00 45.85  ? 145 ALA A N   1 
ATOM   1055 C  CA  . ALA A 1 145 ? 21.070  -15.178 -27.568 1.00 45.01  ? 145 ALA A CA  1 
ATOM   1056 C  C   . ALA A 1 145 ? 19.584  -15.033 -27.276 1.00 49.24  ? 145 ALA A C   1 
ATOM   1057 O  O   . ALA A 1 145 ? 19.154  -15.131 -26.119 1.00 46.94  ? 145 ALA A O   1 
ATOM   1058 C  CB  . ALA A 1 145 ? 21.401  -16.606 -27.983 1.00 46.16  ? 145 ALA A CB  1 
ATOM   1059 N  N   . CYS A 1 146 ? 18.802  -14.753 -28.335 1.00 46.84  ? 146 CYS A N   1 
ATOM   1060 C  CA  . CYS A 1 146 ? 17.354  -14.554 -28.248 1.00 46.88  ? 146 CYS A CA  1 
ATOM   1061 C  C   . CYS A 1 146 ? 16.670  -15.025 -29.519 1.00 47.06  ? 146 CYS A C   1 
ATOM   1062 O  O   . CYS A 1 146 ? 17.314  -15.166 -30.557 1.00 44.74  ? 146 CYS A O   1 
ATOM   1063 C  CB  . CYS A 1 146 ? 17.028  -13.090 -27.965 1.00 48.99  ? 146 CYS A CB  1 
ATOM   1064 S  SG  . CYS A 1 146 ? 17.663  -11.934 -29.210 1.00 55.17  ? 146 CYS A SG  1 
ATOM   1065 N  N   . GLY A 1 147 ? 15.368  -15.223 -29.430 1.00 42.17  ? 147 GLY A N   1 
ATOM   1066 C  CA  . GLY A 1 147 ? 14.530  -15.591 -30.568 1.00 42.58  ? 147 GLY A CA  1 
ATOM   1067 C  C   . GLY A 1 147 ? 13.080  -15.322 -30.251 1.00 44.46  ? 147 GLY A C   1 
ATOM   1068 O  O   . GLY A 1 147 ? 12.674  -15.377 -29.083 1.00 41.39  ? 147 GLY A O   1 
ATOM   1069 N  N   . VAL A 1 148 ? 12.287  -15.033 -31.280 1.00 41.89  ? 148 VAL A N   1 
ATOM   1070 C  CA  . VAL A 1 148 ? 10.865  -14.768 -31.102 1.00 41.67  ? 148 VAL A CA  1 
ATOM   1071 C  C   . VAL A 1 148 ? 10.168  -16.126 -30.941 1.00 45.81  ? 148 VAL A C   1 
ATOM   1072 O  O   . VAL A 1 148 ? 10.481  -17.058 -31.680 1.00 46.73  ? 148 VAL A O   1 
ATOM   1073 C  CB  . VAL A 1 148 ? 10.303  -13.929 -32.292 1.00 45.84  ? 148 VAL A CB  1 
ATOM   1074 C  CG1 . VAL A 1 148 ? 8.827   -13.583 -32.081 1.00 45.47  ? 148 VAL A CG1 1 
ATOM   1075 C  CG2 . VAL A 1 148 ? 11.126  -12.652 -32.479 1.00 45.87  ? 148 VAL A CG2 1 
ATOM   1076 N  N   . ILE A 1 149 ? 9.261   -16.246 -29.956 1.00 41.40  ? 149 ILE A N   1 
ATOM   1077 C  CA  . ILE A 1 149 ? 8.506   -17.475 -29.714 1.00 40.86  ? 149 ILE A CA  1 
ATOM   1078 C  C   . ILE A 1 149 ? 7.394   -17.590 -30.764 1.00 44.94  ? 149 ILE A C   1 
ATOM   1079 O  O   . ILE A 1 149 ? 6.443   -16.802 -30.767 1.00 45.66  ? 149 ILE A O   1 
ATOM   1080 C  CB  . ILE A 1 149 ? 7.988   -17.571 -28.257 1.00 42.68  ? 149 ILE A CB  1 
ATOM   1081 C  CG1 . ILE A 1 149 ? 9.171   -17.449 -27.247 1.00 41.59  ? 149 ILE A CG1 1 
ATOM   1082 C  CG2 . ILE A 1 149 ? 7.184   -18.868 -28.046 1.00 43.22  ? 149 ILE A CG2 1 
ATOM   1083 C  CD1 . ILE A 1 149 ? 8.744   -16.938 -25.831 1.00 43.46  ? 149 ILE A CD1 1 
ATOM   1084 N  N   . GLY A 1 150 ? 7.523   -18.579 -31.636 1.00 42.01  ? 150 GLY A N   1 
ATOM   1085 C  CA  . GLY A 1 150 ? 6.570   -18.781 -32.722 1.00 42.59  ? 150 GLY A CA  1 
ATOM   1086 C  C   . GLY A 1 150 ? 5.727   -20.031 -32.612 1.00 48.34  ? 150 GLY A C   1 
ATOM   1087 O  O   . GLY A 1 150 ? 6.111   -20.982 -31.936 1.00 47.66  ? 150 GLY A O   1 
ATOM   1088 N  N   . ILE A 1 151 ? 4.584   -20.046 -33.317 1.00 46.42  ? 151 ILE A N   1 
ATOM   1089 C  CA  . ILE A 1 151 ? 3.669   -21.191 -33.381 1.00 48.96  ? 151 ILE A CA  1 
ATOM   1090 C  C   . ILE A 1 151 ? 4.352   -22.353 -34.141 1.00 54.98  ? 151 ILE A C   1 
ATOM   1091 O  O   . ILE A 1 151 ? 4.956   -22.129 -35.196 1.00 53.30  ? 151 ILE A O   1 
ATOM   1092 C  CB  . ILE A 1 151 ? 2.305   -20.766 -34.014 1.00 53.16  ? 151 ILE A CB  1 
ATOM   1093 C  CG1 . ILE A 1 151 ? 1.624   -19.668 -33.169 1.00 53.09  ? 151 ILE A CG1 1 
ATOM   1094 C  CG2 . ILE A 1 151 ? 1.365   -21.968 -34.226 1.00 57.48  ? 151 ILE A CG2 1 
ATOM   1095 C  CD1 . ILE A 1 151 ? 0.658   -18.738 -33.944 1.00 62.71  ? 151 ILE A CD1 1 
ATOM   1096 N  N   . ALA A 1 152 ? 4.277   -23.578 -33.580 1.00 54.45  ? 152 ALA A N   1 
ATOM   1097 C  CA  . ALA A 1 152 ? 4.901   -24.770 -34.164 1.00 56.10  ? 152 ALA A CA  1 
ATOM   1098 C  C   . ALA A 1 152 ? 3.891   -25.868 -34.538 1.00 62.01  ? 152 ALA A C   1 
ATOM   1099 O  O   . ALA A 1 152 ? 2.738   -25.812 -34.109 1.00 62.20  ? 152 ALA A O   1 
ATOM   1100 C  CB  . ALA A 1 152 ? 5.943   -25.322 -33.204 1.00 56.75  ? 152 ALA A CB  1 
ATOM   1101 N  N   . GLN A 1 153 ? 4.342   -26.872 -35.326 1.00 60.22  ? 153 GLN A N   1 
ATOM   1102 C  CA  . GLN A 1 153 ? 3.541   -28.023 -35.752 1.00 67.01  ? 153 GLN A CA  1 
ATOM   1103 C  C   . GLN A 1 153 ? 3.585   -29.125 -34.681 1.00 84.99  ? 153 GLN A C   1 
ATOM   1104 O  O   . GLN A 1 153 ? 4.697   -29.589 -34.336 1.00 87.57  ? 153 GLN A O   1 
ATOM   1105 C  CB  . GLN A 1 153 ? 4.045   -28.551 -37.105 1.00 69.74  ? 153 GLN A CB  1 
ATOM   1106 C  CG  . GLN A 1 153 ? 3.101   -29.543 -37.787 1.00 88.40  ? 153 GLN A CG  1 
ATOM   1107 C  CD  . GLN A 1 153 ? 3.453   -29.776 -39.238 1.00 106.45 ? 153 GLN A CD  1 
ATOM   1108 O  OE1 . GLN A 1 153 ? 4.599   -30.075 -39.598 1.00 99.02  ? 153 GLN A OE1 1 
ATOM   1109 N  NE2 . GLN A 1 153 ? 2.461   -29.653 -40.106 1.00 102.04 ? 153 GLN A NE2 1 
ATOM   1110 O  OXT . GLN A 1 153 ? 2.506   -29.516 -34.185 1.00 105.25 ? 153 GLN A OXT 1 
ATOM   1111 N  N   . ALA B 1 1   ? -4.081  0.398   -29.831 1.00 78.14  ? 1   ALA B N   1 
ATOM   1112 C  CA  . ALA B 1 1   ? -3.534  -0.021  -31.120 1.00 76.00  ? 1   ALA B CA  1 
ATOM   1113 C  C   . ALA B 1 1   ? -2.457  -1.103  -30.949 1.00 74.67  ? 1   ALA B C   1 
ATOM   1114 O  O   . ALA B 1 1   ? -1.459  -0.880  -30.257 1.00 74.24  ? 1   ALA B O   1 
ATOM   1115 C  CB  . ALA B 1 1   ? -2.967  1.181   -31.868 1.00 78.01  ? 1   ALA B CB  1 
ATOM   1116 N  N   . THR B 1 2   ? -2.672  -2.276  -31.574 1.00 66.66  ? 2   THR B N   1 
ATOM   1117 C  CA  . THR B 1 2   ? -1.750  -3.409  -31.498 1.00 62.58  ? 2   THR B CA  1 
ATOM   1118 C  C   . THR B 1 2   ? -0.691  -3.281  -32.606 1.00 60.65  ? 2   THR B C   1 
ATOM   1119 O  O   . THR B 1 2   ? -1.002  -2.972  -33.758 1.00 58.61  ? 2   THR B O   1 
ATOM   1120 C  CB  . THR B 1 2   ? -2.503  -4.760  -31.426 1.00 73.85  ? 2   THR B CB  1 
ATOM   1121 O  OG1 . THR B 1 2   ? -1.575  -5.834  -31.271 1.00 74.66  ? 2   THR B OG1 1 
ATOM   1122 C  CG2 . THR B 1 2   ? -3.419  -5.015  -32.611 1.00 74.46  ? 2   THR B CG2 1 
ATOM   1123 N  N   . LYS B 1 3   ? 0.574   -3.442  -32.211 1.00 54.55  ? 3   LYS B N   1 
ATOM   1124 C  CA  . LYS B 1 3   ? 1.719   -3.297  -33.093 1.00 53.19  ? 3   LYS B CA  1 
ATOM   1125 C  C   . LYS B 1 3   ? 2.550   -4.578  -33.114 1.00 52.71  ? 3   LYS B C   1 
ATOM   1126 O  O   . LYS B 1 3   ? 2.644   -5.286  -32.104 1.00 50.97  ? 3   LYS B O   1 
ATOM   1127 C  CB  . LYS B 1 3   ? 2.567   -2.101  -32.634 1.00 57.45  ? 3   LYS B CB  1 
ATOM   1128 C  CG  . LYS B 1 3   ? 3.037   -1.199  -33.763 1.00 82.06  ? 3   LYS B CG  1 
ATOM   1129 C  CD  . LYS B 1 3   ? 3.876   -0.044  -33.226 1.00 95.19  ? 3   LYS B CD  1 
ATOM   1130 C  CE  . LYS B 1 3   ? 4.475   0.798   -34.325 1.00 107.62 ? 3   LYS B CE  1 
ATOM   1131 N  NZ  . LYS B 1 3   ? 5.408   1.822   -33.783 1.00 117.91 ? 3   LYS B NZ  1 
ATOM   1132 N  N   . ALA B 1 4   ? 3.125   -4.884  -34.280 1.00 47.01  ? 4   ALA B N   1 
ATOM   1133 C  CA  . ALA B 1 4   ? 3.978   -6.047  -34.464 1.00 44.29  ? 4   ALA B CA  1 
ATOM   1134 C  C   . ALA B 1 4   ? 5.139   -5.700  -35.380 1.00 47.77  ? 4   ALA B C   1 
ATOM   1135 O  O   . ALA B 1 4   ? 5.134   -4.658  -36.036 1.00 48.65  ? 4   ALA B O   1 
ATOM   1136 C  CB  . ALA B 1 4   ? 3.181   -7.228  -35.002 1.00 44.03  ? 4   ALA B CB  1 
ATOM   1137 N  N   . VAL B 1 5   ? 6.169   -6.533  -35.375 1.00 44.25  ? 5   VAL B N   1 
ATOM   1138 C  CA  . VAL B 1 5   ? 7.355   -6.303  -36.185 1.00 44.23  ? 5   VAL B CA  1 
ATOM   1139 C  C   . VAL B 1 5   ? 7.942   -7.635  -36.636 1.00 47.92  ? 5   VAL B C   1 
ATOM   1140 O  O   . VAL B 1 5   ? 7.785   -8.645  -35.946 1.00 48.08  ? 5   VAL B O   1 
ATOM   1141 C  CB  . VAL B 1 5   ? 8.378   -5.360  -35.466 1.00 48.61  ? 5   VAL B CB  1 
ATOM   1142 C  CG1 . VAL B 1 5   ? 9.072   -6.048  -34.289 1.00 47.46  ? 5   VAL B CG1 1 
ATOM   1143 C  CG2 . VAL B 1 5   ? 9.394   -4.760  -36.444 1.00 49.17  ? 5   VAL B CG2 1 
ATOM   1144 N  N   . CYS B 1 6   ? 8.609   -7.628  -37.792 1.00 44.41  ? 6   CYS B N   1 
ATOM   1145 C  CA  . CYS B 1 6   ? 9.271   -8.789  -38.364 1.00 43.83  ? 6   CYS B CA  1 
ATOM   1146 C  C   . CYS B 1 6   ? 10.621  -8.385  -38.971 1.00 46.10  ? 6   CYS B C   1 
ATOM   1147 O  O   . CYS B 1 6   ? 10.689  -7.442  -39.759 1.00 45.84  ? 6   CYS B O   1 
ATOM   1148 C  CB  . CYS B 1 6   ? 8.370   -9.458  -39.395 1.00 44.39  ? 6   CYS B CB  1 
ATOM   1149 S  SG  . CYS B 1 6   ? 9.083   -10.938 -40.149 1.00 48.53  ? 6   CYS B SG  1 
ATOM   1150 N  N   . VAL B 1 7   ? 11.697  -9.085  -38.575 1.00 43.50  ? 7   VAL B N   1 
ATOM   1151 C  CA  . VAL B 1 7   ? 13.053  -8.870  -39.070 1.00 43.45  ? 7   VAL B CA  1 
ATOM   1152 C  C   . VAL B 1 7   ? 13.314  -10.013 -40.050 1.00 48.78  ? 7   VAL B C   1 
ATOM   1153 O  O   . VAL B 1 7   ? 13.275  -11.177 -39.661 1.00 48.73  ? 7   VAL B O   1 
ATOM   1154 C  CB  . VAL B 1 7   ? 14.140  -8.772  -37.964 1.00 47.42  ? 7   VAL B CB  1 
ATOM   1155 C  CG1 . VAL B 1 7   ? 15.512  -8.458  -38.573 1.00 48.06  ? 7   VAL B CG1 1 
ATOM   1156 C  CG2 . VAL B 1 7   ? 13.773  -7.728  -36.911 1.00 47.43  ? 7   VAL B CG2 1 
ATOM   1157 N  N   . LEU B 1 8   ? 13.505  -9.677  -41.326 1.00 47.10  ? 8   LEU B N   1 
ATOM   1158 C  CA  . LEU B 1 8   ? 13.726  -10.646 -42.399 1.00 47.21  ? 8   LEU B CA  1 
ATOM   1159 C  C   . LEU B 1 8   ? 15.207  -10.906 -42.570 1.00 50.71  ? 8   LEU B C   1 
ATOM   1160 O  O   . LEU B 1 8   ? 15.978  -9.967  -42.773 1.00 50.02  ? 8   LEU B O   1 
ATOM   1161 C  CB  . LEU B 1 8   ? 13.131  -10.141 -43.733 1.00 48.18  ? 8   LEU B CB  1 
ATOM   1162 C  CG  . LEU B 1 8   ? 11.591  -10.030 -43.915 1.00 52.21  ? 8   LEU B CG  1 
ATOM   1163 C  CD1 . LEU B 1 8   ? 10.885  -11.331 -43.630 1.00 51.27  ? 8   LEU B CD1 1 
ATOM   1164 C  CD2 . LEU B 1 8   ? 11.003  -8.905  -43.104 1.00 56.61  ? 8   LEU B CD2 1 
ATOM   1165 N  N   . LYS B 1 9   ? 15.600  -12.182 -42.480 1.00 47.63  ? 9   LYS B N   1 
ATOM   1166 C  CA  . LYS B 1 9   ? 16.974  -12.648 -42.632 1.00 49.18  ? 9   LYS B CA  1 
ATOM   1167 C  C   . LYS B 1 9   ? 16.976  -13.962 -43.407 1.00 53.50  ? 9   LYS B C   1 
ATOM   1168 O  O   . LYS B 1 9   ? 16.051  -14.773 -43.251 1.00 51.41  ? 9   LYS B O   1 
ATOM   1169 C  CB  . LYS B 1 9   ? 17.654  -12.830 -41.263 1.00 51.41  ? 9   LYS B CB  1 
ATOM   1170 C  CG  . LYS B 1 9   ? 18.089  -11.521 -40.610 1.00 70.36  ? 9   LYS B CG  1 
ATOM   1171 C  CD  . LYS B 1 9   ? 18.676  -11.747 -39.215 1.00 83.07  ? 9   LYS B CD  1 
ATOM   1172 C  CE  . LYS B 1 9   ? 18.754  -10.484 -38.383 1.00 93.81  ? 9   LYS B CE  1 
ATOM   1173 N  NZ  . LYS B 1 9   ? 19.726  -9.499  -38.936 1.00 106.32 ? 9   LYS B NZ  1 
ATOM   1174 N  N   . GLY B 1 10  ? 18.003  -14.138 -44.233 1.00 51.40  ? 10  GLY B N   1 
ATOM   1175 C  CA  . GLY B 1 10  ? 18.190  -15.320 -45.069 1.00 53.51  ? 10  GLY B CA  1 
ATOM   1176 C  C   . GLY B 1 10  ? 19.653  -15.667 -45.297 1.00 61.63  ? 10  GLY B C   1 
ATOM   1177 O  O   . GLY B 1 10  ? 20.542  -15.021 -44.722 1.00 63.58  ? 10  GLY B O   1 
ATOM   1178 N  N   . ASP B 1 11  ? 19.916  -16.711 -46.109 1.00 59.29  ? 11  ASP B N   1 
ATOM   1179 C  CA  . ASP B 1 11  ? 21.280  -17.193 -46.392 1.00 62.63  ? 11  ASP B CA  1 
ATOM   1180 C  C   . ASP B 1 11  ? 22.092  -16.283 -47.327 1.00 67.41  ? 11  ASP B C   1 
ATOM   1181 O  O   . ASP B 1 11  ? 23.313  -16.424 -47.401 1.00 68.65  ? 11  ASP B O   1 
ATOM   1182 C  CB  . ASP B 1 11  ? 21.267  -18.647 -46.917 1.00 66.42  ? 11  ASP B CB  1 
ATOM   1183 C  CG  . ASP B 1 11  ? 20.811  -19.672 -45.887 1.00 84.07  ? 11  ASP B CG  1 
ATOM   1184 O  OD1 . ASP B 1 11  ? 21.388  -19.697 -44.767 1.00 85.33  ? 11  ASP B OD1 1 
ATOM   1185 O  OD2 . ASP B 1 11  ? 19.887  -20.458 -46.200 1.00 92.50  ? 11  ASP B OD2 1 
ATOM   1186 N  N   . GLY B 1 12  ? 21.412  -15.383 -48.034 1.00 63.90  ? 12  GLY B N   1 
ATOM   1187 C  CA  . GLY B 1 12  ? 22.043  -14.446 -48.957 1.00 65.19  ? 12  GLY B CA  1 
ATOM   1188 C  C   . GLY B 1 12  ? 22.090  -13.022 -48.431 1.00 66.59  ? 12  GLY B C   1 
ATOM   1189 O  O   . GLY B 1 12  ? 22.160  -12.820 -47.215 1.00 62.90  ? 12  GLY B O   1 
ATOM   1190 N  N   . PRO B 1 13  ? 22.040  -12.000 -49.327 1.00 63.72  ? 13  PRO B N   1 
ATOM   1191 C  CA  . PRO B 1 13  ? 22.074  -10.603 -48.851 1.00 62.67  ? 13  PRO B CA  1 
ATOM   1192 C  C   . PRO B 1 13  ? 20.693  -10.010 -48.519 1.00 62.45  ? 13  PRO B C   1 
ATOM   1193 O  O   . PRO B 1 13  ? 20.609  -8.838  -48.140 1.00 60.42  ? 13  PRO B O   1 
ATOM   1194 C  CB  . PRO B 1 13  ? 22.736  -9.867  -50.020 1.00 66.20  ? 13  PRO B CB  1 
ATOM   1195 C  CG  . PRO B 1 13  ? 22.320  -10.650 -51.231 1.00 70.98  ? 13  PRO B CG  1 
ATOM   1196 C  CD  . PRO B 1 13  ? 21.980  -12.058 -50.805 1.00 65.79  ? 13  PRO B CD  1 
ATOM   1197 N  N   . VAL B 1 14  ? 19.615  -10.800 -48.679 1.00 59.09  ? 14  VAL B N   1 
ATOM   1198 C  CA  . VAL B 1 14  ? 18.248  -10.333 -48.434 1.00 58.35  ? 14  VAL B CA  1 
ATOM   1199 C  C   . VAL B 1 14  ? 18.020  -10.069 -46.952 1.00 60.98  ? 14  VAL B C   1 
ATOM   1200 O  O   . VAL B 1 14  ? 18.136  -10.987 -46.142 1.00 62.13  ? 14  VAL B O   1 
ATOM   1201 C  CB  . VAL B 1 14  ? 17.131  -11.231 -49.041 1.00 62.18  ? 14  VAL B CB  1 
ATOM   1202 C  CG1 . VAL B 1 14  ? 15.760  -10.594 -48.845 1.00 61.28  ? 14  VAL B CG1 1 
ATOM   1203 C  CG2 . VAL B 1 14  ? 17.369  -11.511 -50.519 1.00 63.70  ? 14  VAL B CG2 1 
ATOM   1204 N  N   . GLN B 1 15  ? 17.709  -8.807  -46.606 1.00 55.57  ? 15  GLN B N   1 
ATOM   1205 C  CA  . GLN B 1 15  ? 17.399  -8.373  -45.234 1.00 53.04  ? 15  GLN B CA  1 
ATOM   1206 C  C   . GLN B 1 15  ? 16.366  -7.245  -45.226 1.00 54.74  ? 15  GLN B C   1 
ATOM   1207 O  O   . GLN B 1 15  ? 16.261  -6.497  -46.201 1.00 55.50  ? 15  GLN B O   1 
ATOM   1208 C  CB  . GLN B 1 15  ? 18.656  -8.015  -44.418 1.00 54.69  ? 15  GLN B CB  1 
ATOM   1209 C  CG  . GLN B 1 15  ? 19.507  -6.891  -44.994 1.00 74.45  ? 15  GLN B CG  1 
ATOM   1210 C  CD  . GLN B 1 15  ? 20.735  -6.647  -44.158 1.00 97.18  ? 15  GLN B CD  1 
ATOM   1211 O  OE1 . GLN B 1 15  ? 20.731  -5.839  -43.223 1.00 93.31  ? 15  GLN B OE1 1 
ATOM   1212 N  NE2 . GLN B 1 15  ? 21.815  -7.344  -44.475 1.00 90.48  ? 15  GLN B NE2 1 
ATOM   1213 N  N   . GLY B 1 16  ? 15.605  -7.146  -44.142 1.00 48.69  ? 16  GLY B N   1 
ATOM   1214 C  CA  . GLY B 1 16  ? 14.568  -6.132  -44.033 1.00 48.76  ? 16  GLY B CA  1 
ATOM   1215 C  C   . GLY B 1 16  ? 13.832  -6.085  -42.713 1.00 52.17  ? 16  GLY B C   1 
ATOM   1216 O  O   . GLY B 1 16  ? 13.924  -7.006  -41.892 1.00 50.33  ? 16  GLY B O   1 
ATOM   1217 N  N   . ILE B 1 17  ? 13.135  -4.968  -42.489 1.00 48.64  ? 17  ILE B N   1 
ATOM   1218 C  CA  . ILE B 1 17  ? 12.343  -4.725  -41.283 1.00 46.65  ? 17  ILE B CA  1 
ATOM   1219 C  C   . ILE B 1 17  ? 10.923  -4.396  -41.730 1.00 49.67  ? 17  ILE B C   1 
ATOM   1220 O  O   . ILE B 1 17  ? 10.726  -3.436  -42.485 1.00 49.37  ? 17  ILE B O   1 
ATOM   1221 C  CB  . ILE B 1 17  ? 12.943  -3.618  -40.367 1.00 50.48  ? 17  ILE B CB  1 
ATOM   1222 C  CG1 . ILE B 1 17  ? 14.372  -4.008  -39.854 1.00 51.79  ? 17  ILE B CG1 1 
ATOM   1223 C  CG2 . ILE B 1 17  ? 11.975  -3.311  -39.185 1.00 48.42  ? 17  ILE B CG2 1 
ATOM   1224 C  CD1 . ILE B 1 17  ? 15.133  -2.931  -39.015 1.00 57.12  ? 17  ILE B CD1 1 
ATOM   1225 N  N   . ILE B 1 18  ? 9.943   -5.202  -41.284 1.00 45.80  ? 18  ILE B N   1 
ATOM   1226 C  CA  . ILE B 1 18  ? 8.531   -4.999  -41.634 1.00 45.57  ? 18  ILE B CA  1 
ATOM   1227 C  C   . ILE B 1 18  ? 7.715   -4.745  -40.371 1.00 49.22  ? 18  ILE B C   1 
ATOM   1228 O  O   . ILE B 1 18  ? 7.789   -5.512  -39.415 1.00 48.46  ? 18  ILE B O   1 
ATOM   1229 C  CB  . ILE B 1 18  ? 7.954   -6.131  -42.541 1.00 47.61  ? 18  ILE B CB  1 
ATOM   1230 C  CG1 . ILE B 1 18  ? 8.689   -6.220  -43.908 1.00 48.03  ? 18  ILE B CG1 1 
ATOM   1231 C  CG2 . ILE B 1 18  ? 6.425   -6.023  -42.736 1.00 48.46  ? 18  ILE B CG2 1 
ATOM   1232 C  CD1 . ILE B 1 18  ? 8.720   -4.937  -44.793 1.00 54.34  ? 18  ILE B CD1 1 
ATOM   1233 N  N   . ASN B 1 19  ? 6.985   -3.633  -40.360 1.00 46.50  ? 19  ASN B N   1 
ATOM   1234 C  CA  . ASN B 1 19  ? 6.149   -3.216  -39.239 1.00 46.75  ? 19  ASN B CA  1 
ATOM   1235 C  C   . ASN B 1 19  ? 4.700   -3.504  -39.587 1.00 49.29  ? 19  ASN B C   1 
ATOM   1236 O  O   . ASN B 1 19  ? 4.342   -3.487  -40.760 1.00 47.53  ? 19  ASN B O   1 
ATOM   1237 C  CB  . ASN B 1 19  ? 6.329   -1.715  -38.963 1.00 48.46  ? 19  ASN B CB  1 
ATOM   1238 C  CG  . ASN B 1 19  ? 7.766   -1.275  -38.822 1.00 63.37  ? 19  ASN B CG  1 
ATOM   1239 O  OD1 . ASN B 1 19  ? 8.376   -0.714  -39.743 1.00 55.31  ? 19  ASN B OD1 1 
ATOM   1240 N  ND2 . ASN B 1 19  ? 8.337   -1.536  -37.672 1.00 51.57  ? 19  ASN B ND2 1 
ATOM   1241 N  N   . PHE B 1 20  ? 3.883   -3.798  -38.566 1.00 46.30  ? 20  PHE B N   1 
ATOM   1242 C  CA  . PHE B 1 20  ? 2.447   -4.045  -38.690 1.00 45.59  ? 20  PHE B CA  1 
ATOM   1243 C  C   . PHE B 1 20  ? 1.758   -3.234  -37.597 1.00 52.22  ? 20  PHE B C   1 
ATOM   1244 O  O   . PHE B 1 20  ? 2.262   -3.179  -36.471 1.00 52.25  ? 20  PHE B O   1 
ATOM   1245 C  CB  . PHE B 1 20  ? 2.092   -5.531  -38.492 1.00 45.36  ? 20  PHE B CB  1 
ATOM   1246 C  CG  . PHE B 1 20  ? 2.825   -6.535  -39.336 1.00 45.50  ? 20  PHE B CG  1 
ATOM   1247 C  CD1 . PHE B 1 20  ? 4.098   -6.969  -38.981 1.00 48.06  ? 20  PHE B CD1 1 
ATOM   1248 C  CD2 . PHE B 1 20  ? 2.231   -7.079  -40.471 1.00 47.62  ? 20  PHE B CD2 1 
ATOM   1249 C  CE1 . PHE B 1 20  ? 4.784   -7.898  -39.771 1.00 48.02  ? 20  PHE B CE1 1 
ATOM   1250 C  CE2 . PHE B 1 20  ? 2.914   -8.013  -41.254 1.00 49.20  ? 20  PHE B CE2 1 
ATOM   1251 C  CZ  . PHE B 1 20  ? 4.181   -8.428  -40.888 1.00 46.11  ? 20  PHE B CZ  1 
ATOM   1252 N  N   . GLU B 1 21  ? 0.616   -2.612  -37.924 1.00 51.14  ? 21  GLU B N   1 
ATOM   1253 C  CA  . GLU B 1 21  ? -0.193  -1.847  -36.975 1.00 53.41  ? 21  GLU B CA  1 
ATOM   1254 C  C   . GLU B 1 21  ? -1.678  -1.987  -37.300 1.00 56.58  ? 21  GLU B C   1 
ATOM   1255 O  O   . GLU B 1 21  ? -2.084  -1.796  -38.448 1.00 56.02  ? 21  GLU B O   1 
ATOM   1256 C  CB  . GLU B 1 21  ? 0.226   -0.369  -36.916 1.00 57.12  ? 21  GLU B CB  1 
ATOM   1257 C  CG  . GLU B 1 21  ? -0.353  0.361   -35.711 1.00 72.20  ? 21  GLU B CG  1 
ATOM   1258 C  CD  . GLU B 1 21  ? -0.143  1.862   -35.673 1.00 102.37 ? 21  GLU B CD  1 
ATOM   1259 O  OE1 . GLU B 1 21  ? -0.528  2.548   -36.648 1.00 98.36  ? 21  GLU B OE1 1 
ATOM   1260 O  OE2 . GLU B 1 21  ? 0.387   2.356   -34.651 1.00 102.17 ? 21  GLU B OE2 1 
ATOM   1261 N  N   . GLN B 1 22  ? -2.476  -2.327  -36.274 1.00 53.20  ? 22  GLN B N   1 
ATOM   1262 C  CA  . GLN B 1 22  ? -3.918  -2.506  -36.371 1.00 53.80  ? 22  GLN B CA  1 
ATOM   1263 C  C   . GLN B 1 22  ? -4.529  -1.728  -35.197 1.00 61.10  ? 22  GLN B C   1 
ATOM   1264 O  O   . GLN B 1 22  ? -4.454  -2.164  -34.044 1.00 58.77  ? 22  GLN B O   1 
ATOM   1265 C  CB  . GLN B 1 22  ? -4.265  -4.010  -36.341 1.00 53.18  ? 22  GLN B CB  1 
ATOM   1266 C  CG  . GLN B 1 22  ? -5.714  -4.335  -36.692 1.00 55.92  ? 22  GLN B CG  1 
ATOM   1267 C  CD  . GLN B 1 22  ? -6.077  -5.802  -36.577 1.00 64.79  ? 22  GLN B CD  1 
ATOM   1268 O  OE1 . GLN B 1 22  ? -5.436  -6.584  -35.874 1.00 59.18  ? 22  GLN B OE1 1 
ATOM   1269 N  NE2 . GLN B 1 22  ? -7.130  -6.211  -37.269 1.00 57.25  ? 22  GLN B NE2 1 
ATOM   1270 N  N   . LYS B 1 23  ? -5.050  -0.528  -35.490 1.00 62.76  ? 23  LYS B N   1 
ATOM   1271 C  CA  . LYS B 1 23  ? -5.632  0.360   -34.477 1.00 65.69  ? 23  LYS B CA  1 
ATOM   1272 C  C   . LYS B 1 23  ? -6.965  -0.161  -33.925 1.00 70.77  ? 23  LYS B C   1 
ATOM   1273 O  O   . LYS B 1 23  ? -7.253  0.056   -32.746 1.00 71.76  ? 23  LYS B O   1 
ATOM   1274 C  CB  . LYS B 1 23  ? -5.737  1.804   -34.991 1.00 71.35  ? 23  LYS B CB  1 
ATOM   1275 C  CG  . LYS B 1 23  ? -4.361  2.457   -35.150 1.00 87.83  ? 23  LYS B CG  1 
ATOM   1276 C  CD  . LYS B 1 23  ? -4.432  3.936   -35.475 1.00 102.51 ? 23  LYS B CD  1 
ATOM   1277 C  CE  . LYS B 1 23  ? -3.054  4.549   -35.483 1.00 112.66 ? 23  LYS B CE  1 
ATOM   1278 N  NZ  . LYS B 1 23  ? -3.103  6.011   -35.741 1.00 125.62 ? 23  LYS B NZ  1 
ATOM   1279 N  N   . GLU B 1 24  ? -7.742  -0.890  -34.748 1.00 66.66  ? 24  GLU B N   1 
ATOM   1280 C  CA  . GLU B 1 24  ? -9.012  -1.505  -34.340 1.00 67.25  ? 24  GLU B CA  1 
ATOM   1281 C  C   . GLU B 1 24  ? -8.983  -3.000  -34.676 1.00 67.76  ? 24  GLU B C   1 
ATOM   1282 O  O   . GLU B 1 24  ? -8.550  -3.358  -35.766 1.00 65.91  ? 24  GLU B O   1 
ATOM   1283 C  CB  . GLU B 1 24  ? -10.208 -0.808  -35.013 1.00 71.57  ? 24  GLU B CB  1 
ATOM   1284 C  CG  . GLU B 1 24  ? -10.593 0.506   -34.350 1.00 87.62  ? 24  GLU B CG  1 
ATOM   1285 C  CD  . GLU B 1 24  ? -10.447 1.763   -35.189 1.00 116.66 ? 24  GLU B CD  1 
ATOM   1286 O  OE1 . GLU B 1 24  ? -10.455 1.666   -36.438 1.00 112.81 ? 24  GLU B OE1 1 
ATOM   1287 O  OE2 . GLU B 1 24  ? -10.342 2.857   -34.589 1.00 116.30 ? 24  GLU B OE2 1 
ATOM   1288 N  N   . SER B 1 25  ? -9.441  -3.866  -33.742 1.00 63.66  ? 25  SER B N   1 
ATOM   1289 C  CA  . SER B 1 25  ? -9.457  -5.335  -33.890 1.00 61.74  ? 25  SER B CA  1 
ATOM   1290 C  C   . SER B 1 25  ? -10.236 -5.855  -35.121 1.00 65.50  ? 25  SER B C   1 
ATOM   1291 O  O   . SER B 1 25  ? -9.932  -6.935  -35.626 1.00 63.92  ? 25  SER B O   1 
ATOM   1292 C  CB  . SER B 1 25  ? -9.975  -5.999  -32.615 1.00 65.49  ? 25  SER B CB  1 
ATOM   1293 O  OG  . SER B 1 25  ? -11.381 -5.852  -32.466 1.00 77.02  ? 25  SER B OG  1 
ATOM   1294 N  N   . ASN B 1 26  ? -11.250 -5.103  -35.570 1.00 64.12  ? 26  ASN B N   1 
ATOM   1295 C  CA  . ASN B 1 26  ? -12.075 -5.455  -36.732 1.00 64.52  ? 26  ASN B CA  1 
ATOM   1296 C  C   . ASN B 1 26  ? -11.755 -4.565  -37.947 1.00 68.65  ? 26  ASN B C   1 
ATOM   1297 O  O   . ASN B 1 26  ? -12.474 -4.596  -38.951 1.00 68.89  ? 26  ASN B O   1 
ATOM   1298 C  CB  . ASN B 1 26  ? -13.570 -5.437  -36.367 1.00 65.50  ? 26  ASN B CB  1 
ATOM   1299 C  CG  . ASN B 1 26  ? -14.120 -4.070  -36.048 1.00 78.97  ? 26  ASN B CG  1 
ATOM   1300 O  OD1 . ASN B 1 26  ? -13.444 -3.218  -35.461 1.00 72.84  ? 26  ASN B OD1 1 
ATOM   1301 N  ND2 . ASN B 1 26  ? -15.364 -3.831  -36.430 1.00 71.25  ? 26  ASN B ND2 1 
ATOM   1302 N  N   . GLY B 1 27  ? -10.655 -3.816  -37.847 1.00 64.59  ? 27  GLY B N   1 
ATOM   1303 C  CA  . GLY B 1 27  ? -10.178 -2.920  -38.895 1.00 64.79  ? 27  GLY B CA  1 
ATOM   1304 C  C   . GLY B 1 27  ? -8.947  -3.426  -39.631 1.00 65.48  ? 27  GLY B C   1 
ATOM   1305 O  O   . GLY B 1 27  ? -8.355  -4.438  -39.236 1.00 62.69  ? 27  GLY B O   1 
ATOM   1306 N  N   . PRO B 1 28  ? -8.520  -2.725  -40.710 1.00 61.88  ? 28  PRO B N   1 
ATOM   1307 C  CA  . PRO B 1 28  ? -7.349  -3.200  -41.474 1.00 59.14  ? 28  PRO B CA  1 
ATOM   1308 C  C   . PRO B 1 28  ? -5.994  -3.096  -40.766 1.00 59.43  ? 28  PRO B C   1 
ATOM   1309 O  O   . PRO B 1 28  ? -5.803  -2.287  -39.851 1.00 59.21  ? 28  PRO B O   1 
ATOM   1310 C  CB  . PRO B 1 28  ? -7.380  -2.363  -42.756 1.00 62.73  ? 28  PRO B CB  1 
ATOM   1311 C  CG  . PRO B 1 28  ? -8.180  -1.159  -42.423 1.00 70.20  ? 28  PRO B CG  1 
ATOM   1312 C  CD  . PRO B 1 28  ? -9.129  -1.522  -41.321 1.00 66.13  ? 28  PRO B CD  1 
ATOM   1313 N  N   . VAL B 1 29  ? -5.058  -3.954  -41.189 1.00 53.09  ? 29  VAL B N   1 
ATOM   1314 C  CA  . VAL B 1 29  ? -3.677  -3.974  -40.690 1.00 50.65  ? 29  VAL B CA  1 
ATOM   1315 C  C   . VAL B 1 29  ? -2.810  -3.210  -41.702 1.00 56.31  ? 29  VAL B C   1 
ATOM   1316 O  O   . VAL B 1 29  ? -2.810  -3.536  -42.896 1.00 55.09  ? 29  VAL B O   1 
ATOM   1317 C  CB  . VAL B 1 29  ? -3.135  -5.416  -40.463 1.00 50.77  ? 29  VAL B CB  1 
ATOM   1318 C  CG1 . VAL B 1 29  ? -1.696  -5.402  -39.936 1.00 49.32  ? 29  VAL B CG1 1 
ATOM   1319 C  CG2 . VAL B 1 29  ? -4.042  -6.216  -39.537 1.00 49.77  ? 29  VAL B CG2 1 
ATOM   1320 N  N   . LYS B 1 30  ? -2.075  -2.197  -41.211 1.00 55.43  ? 30  LYS B N   1 
ATOM   1321 C  CA  . LYS B 1 30  ? -1.115  -1.427  -42.003 1.00 55.96  ? 30  LYS B CA  1 
ATOM   1322 C  C   . LYS B 1 30  ? 0.221   -2.166  -41.907 1.00 57.20  ? 30  LYS B C   1 
ATOM   1323 O  O   . LYS B 1 30  ? 0.656   -2.516  -40.808 1.00 52.96  ? 30  LYS B O   1 
ATOM   1324 C  CB  . LYS B 1 30  ? -0.987  0.010   -41.467 1.00 60.84  ? 30  LYS B CB  1 
ATOM   1325 C  CG  . LYS B 1 30  ? -0.357  0.984   -42.457 1.00 78.22  ? 30  LYS B CG  1 
ATOM   1326 C  CD  . LYS B 1 30  ? -0.475  2.430   -41.977 1.00 89.41  ? 30  LYS B CD  1 
ATOM   1327 C  CE  . LYS B 1 30  ? 0.824   2.989   -41.443 1.00 94.92  ? 30  LYS B CE  1 
ATOM   1328 N  NZ  . LYS B 1 30  ? 1.787   3.317   -42.531 1.00 97.82  ? 30  LYS B NZ  1 
ATOM   1329 N  N   . VAL B 1 31  ? 0.838   -2.455  -43.060 1.00 54.87  ? 31  VAL B N   1 
ATOM   1330 C  CA  . VAL B 1 31  ? 2.114   -3.160  -43.110 1.00 54.29  ? 31  VAL B CA  1 
ATOM   1331 C  C   . VAL B 1 31  ? 3.086   -2.337  -43.958 1.00 58.24  ? 31  VAL B C   1 
ATOM   1332 O  O   . VAL B 1 31  ? 2.821   -2.061  -45.128 1.00 58.00  ? 31  VAL B O   1 
ATOM   1333 C  CB  . VAL B 1 31  ? 2.018   -4.681  -43.471 1.00 57.38  ? 31  VAL B CB  1 
ATOM   1334 C  CG1 . VAL B 1 31  ? 0.698   -5.056  -44.123 1.00 57.89  ? 31  VAL B CG1 1 
ATOM   1335 C  CG2 . VAL B 1 31  ? 3.217   -5.197  -44.260 1.00 56.19  ? 31  VAL B CG2 1 
ATOM   1336 N  N   . TRP B 1 32  ? 4.175   -1.867  -43.314 1.00 55.31  ? 32  TRP B N   1 
ATOM   1337 C  CA  . TRP B 1 32  ? 5.167   -1.003  -43.949 1.00 56.36  ? 32  TRP B CA  1 
ATOM   1338 C  C   . TRP B 1 32  ? 6.599   -1.315  -43.539 1.00 59.21  ? 32  TRP B C   1 
ATOM   1339 O  O   . TRP B 1 32  ? 6.828   -1.932  -42.501 1.00 57.64  ? 32  TRP B O   1 
ATOM   1340 C  CB  . TRP B 1 32  ? 4.826   0.483   -43.711 1.00 57.32  ? 32  TRP B CB  1 
ATOM   1341 C  CG  . TRP B 1 32  ? 5.160   1.001   -42.344 1.00 58.42  ? 32  TRP B CG  1 
ATOM   1342 C  CD1 . TRP B 1 32  ? 6.247   1.745   -41.996 1.00 62.29  ? 32  TRP B CD1 1 
ATOM   1343 C  CD2 . TRP B 1 32  ? 4.399   0.812   -41.141 1.00 57.79  ? 32  TRP B CD2 1 
ATOM   1344 N  NE1 . TRP B 1 32  ? 6.215   2.034   -40.652 1.00 61.86  ? 32  TRP B NE1 1 
ATOM   1345 C  CE2 . TRP B 1 32  ? 5.082   1.488   -40.104 1.00 62.46  ? 32  TRP B CE2 1 
ATOM   1346 C  CE3 . TRP B 1 32  ? 3.180   0.175   -40.846 1.00 58.43  ? 32  TRP B CE3 1 
ATOM   1347 C  CZ2 . TRP B 1 32  ? 4.607   1.514   -38.785 1.00 61.76  ? 32  TRP B CZ2 1 
ATOM   1348 C  CZ3 . TRP B 1 32  ? 2.703   0.208   -39.543 1.00 59.86  ? 32  TRP B CZ3 1 
ATOM   1349 C  CH2 . TRP B 1 32  ? 3.414   0.865   -38.527 1.00 61.19  ? 32  TRP B CH2 1 
ATOM   1350 N  N   . GLY B 1 33  ? 7.548   -0.859  -44.350 1.00 56.31  ? 33  GLY B N   1 
ATOM   1351 C  CA  . GLY B 1 33  ? 8.968   -1.049  -44.092 1.00 55.74  ? 33  GLY B CA  1 
ATOM   1352 C  C   . GLY B 1 33  ? 9.800   -1.080  -45.352 1.00 60.63  ? 33  GLY B C   1 
ATOM   1353 O  O   . GLY B 1 33  ? 9.378   -0.563  -46.394 1.00 61.65  ? 33  GLY B O   1 
ATOM   1354 N  N   . SER B 1 34  ? 10.991  -1.694  -45.264 1.00 56.66  ? 34  SER B N   1 
ATOM   1355 C  CA  . SER B 1 34  ? 11.912  -1.792  -46.398 1.00 58.06  ? 34  SER B CA  1 
ATOM   1356 C  C   . SER B 1 34  ? 12.680  -3.112  -46.396 1.00 59.36  ? 34  SER B C   1 
ATOM   1357 O  O   . SER B 1 34  ? 13.026  -3.612  -45.330 1.00 56.77  ? 34  SER B O   1 
ATOM   1358 C  CB  . SER B 1 34  ? 12.887  -0.618  -46.392 1.00 65.09  ? 34  SER B CB  1 
ATOM   1359 O  OG  . SER B 1 34  ? 13.673  -0.590  -47.571 1.00 77.62  ? 34  SER B OG  1 
ATOM   1360 N  N   . ILE B 1 35  ? 12.923  -3.676  -47.597 1.00 56.06  ? 35  ILE B N   1 
ATOM   1361 C  CA  . ILE B 1 35  ? 13.683  -4.918  -47.820 1.00 54.85  ? 35  ILE B CA  1 
ATOM   1362 C  C   . ILE B 1 35  ? 14.773  -4.625  -48.867 1.00 59.93  ? 35  ILE B C   1 
ATOM   1363 O  O   . ILE B 1 35  ? 14.463  -4.071  -49.923 1.00 61.35  ? 35  ILE B O   1 
ATOM   1364 C  CB  . ILE B 1 35  ? 12.798  -6.131  -48.273 1.00 56.47  ? 35  ILE B CB  1 
ATOM   1365 C  CG1 . ILE B 1 35  ? 11.509  -6.293  -47.424 1.00 55.26  ? 35  ILE B CG1 1 
ATOM   1366 C  CG2 . ILE B 1 35  ? 13.622  -7.434  -48.280 1.00 56.44  ? 35  ILE B CG2 1 
ATOM   1367 C  CD1 . ILE B 1 35  ? 10.348  -6.987  -48.158 1.00 61.06  ? 35  ILE B CD1 1 
ATOM   1368 N  N   . LYS B 1 36  ? 16.030  -5.004  -48.575 1.00 56.21  ? 36  LYS B N   1 
ATOM   1369 C  CA  . LYS B 1 36  ? 17.168  -4.832  -49.485 1.00 57.91  ? 36  LYS B CA  1 
ATOM   1370 C  C   . LYS B 1 36  ? 17.805  -6.186  -49.884 1.00 60.10  ? 36  LYS B C   1 
ATOM   1371 O  O   . LYS B 1 36  ? 17.456  -7.218  -49.304 1.00 57.07  ? 36  LYS B O   1 
ATOM   1372 C  CB  . LYS B 1 36  ? 18.203  -3.825  -48.928 1.00 61.56  ? 36  LYS B CB  1 
ATOM   1373 C  CG  . LYS B 1 36  ? 18.832  -4.185  -47.589 1.00 71.59  ? 36  LYS B CG  1 
ATOM   1374 C  CD  . LYS B 1 36  ? 19.788  -3.092  -47.143 1.00 85.51  ? 36  LYS B CD  1 
ATOM   1375 C  CE  . LYS B 1 36  ? 20.808  -3.577  -46.144 1.00 94.98  ? 36  LYS B CE  1 
ATOM   1376 N  NZ  . LYS B 1 36  ? 21.711  -2.482  -45.714 1.00 106.71 ? 36  LYS B NZ  1 
ATOM   1377 N  N   . GLY B 1 37  ? 18.683  -6.163  -50.894 1.00 57.83  ? 37  GLY B N   1 
ATOM   1378 C  CA  . GLY B 1 37  ? 19.377  -7.346  -51.397 1.00 57.40  ? 37  GLY B CA  1 
ATOM   1379 C  C   . GLY B 1 37  ? 18.566  -8.206  -52.341 1.00 61.26  ? 37  GLY B C   1 
ATOM   1380 O  O   . GLY B 1 37  ? 18.920  -9.359  -52.595 1.00 62.82  ? 37  GLY B O   1 
ATOM   1381 N  N   . LEU B 1 38  ? 17.487  -7.644  -52.891 1.00 56.59  ? 38  LEU B N   1 
ATOM   1382 C  CA  . LEU B 1 38  ? 16.571  -8.306  -53.818 1.00 55.64  ? 38  LEU B CA  1 
ATOM   1383 C  C   . LEU B 1 38  ? 16.988  -8.075  -55.261 1.00 62.31  ? 38  LEU B C   1 
ATOM   1384 O  O   . LEU B 1 38  ? 17.606  -7.055  -55.573 1.00 62.52  ? 38  LEU B O   1 
ATOM   1385 C  CB  . LEU B 1 38  ? 15.165  -7.683  -53.625 1.00 54.74  ? 38  LEU B CB  1 
ATOM   1386 C  CG  . LEU B 1 38  ? 14.039  -8.431  -52.872 1.00 56.87  ? 38  LEU B CG  1 
ATOM   1387 C  CD1 . LEU B 1 38  ? 14.518  -9.591  -52.060 1.00 54.31  ? 38  LEU B CD1 1 
ATOM   1388 C  CD2 . LEU B 1 38  ? 13.208  -7.479  -52.024 1.00 56.64  ? 38  LEU B CD2 1 
ATOM   1389 N  N   . THR B 1 39  ? 16.583  -8.985  -56.163 1.00 60.04  ? 39  THR B N   1 
ATOM   1390 C  CA  . THR B 1 39  ? 16.763  -8.777  -57.594 1.00 62.46  ? 39  THR B CA  1 
ATOM   1391 C  C   . THR B 1 39  ? 15.668  -7.770  -57.968 1.00 68.25  ? 39  THR B C   1 
ATOM   1392 O  O   . THR B 1 39  ? 14.663  -7.676  -57.254 1.00 67.62  ? 39  THR B O   1 
ATOM   1393 C  CB  . THR B 1 39  ? 16.563  -10.076 -58.405 1.00 69.26  ? 39  THR B CB  1 
ATOM   1394 O  OG1 . THR B 1 39  ? 15.408  -10.767 -57.933 1.00 60.23  ? 39  THR B OG1 1 
ATOM   1395 C  CG2 . THR B 1 39  ? 17.777  -10.988 -58.382 1.00 68.12  ? 39  THR B CG2 1 
ATOM   1396 N  N   . GLU B 1 40  ? 15.869  -7.000  -59.042 1.00 67.26  ? 40  GLU B N   1 
ATOM   1397 C  CA  . GLU B 1 40  ? 14.897  -6.021  -59.534 1.00 68.10  ? 40  GLU B CA  1 
ATOM   1398 C  C   . GLU B 1 40  ? 13.624  -6.754  -59.971 1.00 71.97  ? 40  GLU B C   1 
ATOM   1399 O  O   . GLU B 1 40  ? 13.707  -7.829  -60.572 1.00 72.05  ? 40  GLU B O   1 
ATOM   1400 C  CB  . GLU B 1 40  ? 15.495  -5.249  -60.726 1.00 72.38  ? 40  GLU B CB  1 
ATOM   1401 C  CG  . GLU B 1 40  ? 14.727  -3.997  -61.125 1.00 81.94  ? 40  GLU B CG  1 
ATOM   1402 C  CD  . GLU B 1 40  ? 15.345  -3.171  -62.240 1.00 98.14  ? 40  GLU B CD  1 
ATOM   1403 O  OE1 . GLU B 1 40  ? 16.522  -3.413  -62.595 1.00 88.16  ? 40  GLU B OE1 1 
ATOM   1404 O  OE2 . GLU B 1 40  ? 14.651  -2.263  -62.749 1.00 91.97  ? 40  GLU B OE2 1 
ATOM   1405 N  N   . GLY B 1 41  ? 12.472  -6.176  -59.644 1.00 67.99  ? 41  GLY B N   1 
ATOM   1406 C  CA  . GLY B 1 41  ? 11.180  -6.749  -59.997 1.00 67.29  ? 41  GLY B CA  1 
ATOM   1407 C  C   . GLY B 1 41  ? 10.326  -7.144  -58.812 1.00 68.21  ? 41  GLY B C   1 
ATOM   1408 O  O   . GLY B 1 41  ? 10.617  -6.774  -57.671 1.00 66.64  ? 41  GLY B O   1 
ATOM   1409 N  N   . LEU B 1 42  ? 9.274   -7.924  -59.084 1.00 64.28  ? 42  LEU B N   1 
ATOM   1410 C  CA  . LEU B 1 42  ? 8.288   -8.386  -58.100 1.00 62.44  ? 42  LEU B CA  1 
ATOM   1411 C  C   . LEU B 1 42  ? 8.742   -9.637  -57.354 1.00 62.23  ? 42  LEU B C   1 
ATOM   1412 O  O   . LEU B 1 42  ? 9.374   -10.519 -57.955 1.00 61.68  ? 42  LEU B O   1 
ATOM   1413 C  CB  . LEU B 1 42  ? 6.944   -8.649  -58.812 1.00 63.75  ? 42  LEU B CB  1 
ATOM   1414 C  CG  . LEU B 1 42  ? 6.002   -7.460  -59.046 1.00 70.37  ? 42  LEU B CG  1 
ATOM   1415 C  CD1 . LEU B 1 42  ? 6.475   -6.578  -60.192 1.00 73.25  ? 42  LEU B CD1 1 
ATOM   1416 C  CD2 . LEU B 1 42  ? 4.633   -7.950  -59.426 1.00 74.54  ? 42  LEU B CD2 1 
ATOM   1417 N  N   . HIS B 1 43  ? 8.430   -9.698  -56.034 1.00 55.29  ? 43  HIS B N   1 
ATOM   1418 C  CA  . HIS B 1 43  ? 8.742   -10.800 -55.124 1.00 53.26  ? 43  HIS B CA  1 
ATOM   1419 C  C   . HIS B 1 43  ? 7.540   -11.167 -54.248 1.00 55.43  ? 43  HIS B C   1 
ATOM   1420 O  O   . HIS B 1 43  ? 6.984   -10.296 -53.564 1.00 54.01  ? 43  HIS B O   1 
ATOM   1421 C  CB  . HIS B 1 43  ? 9.943   -10.439 -54.209 1.00 53.26  ? 43  HIS B CB  1 
ATOM   1422 C  CG  . HIS B 1 43  ? 11.203  -10.234 -54.986 1.00 57.09  ? 43  HIS B CG  1 
ATOM   1423 N  ND1 . HIS B 1 43  ? 12.029  -11.290 -55.299 1.00 58.89  ? 43  HIS B ND1 1 
ATOM   1424 C  CD2 . HIS B 1 43  ? 11.698  -9.106  -55.546 1.00 59.61  ? 43  HIS B CD2 1 
ATOM   1425 C  CE1 . HIS B 1 43  ? 13.012  -10.774 -56.017 1.00 59.85  ? 43  HIS B CE1 1 
ATOM   1426 N  NE2 . HIS B 1 43  ? 12.847  -9.465  -56.202 1.00 60.71  ? 43  HIS B NE2 1 
ATOM   1427 N  N   . GLY B 1 44  ? 7.174   -12.453 -54.259 1.00 51.55  ? 44  GLY B N   1 
ATOM   1428 C  CA  . GLY B 1 44  ? 6.092   -12.997 -53.444 1.00 49.63  ? 44  GLY B CA  1 
ATOM   1429 C  C   . GLY B 1 44  ? 6.300   -12.645 -51.984 1.00 52.88  ? 44  GLY B C   1 
ATOM   1430 O  O   . GLY B 1 44  ? 7.397   -12.846 -51.451 1.00 51.82  ? 44  GLY B O   1 
ATOM   1431 N  N   . PHE B 1 45  ? 5.273   -12.048 -51.349 1.00 49.05  ? 45  PHE B N   1 
ATOM   1432 C  CA  . PHE B 1 45  ? 5.326   -11.564 -49.972 1.00 48.68  ? 45  PHE B CA  1 
ATOM   1433 C  C   . PHE B 1 45  ? 4.201   -12.263 -49.223 1.00 52.78  ? 45  PHE B C   1 
ATOM   1434 O  O   . PHE B 1 45  ? 3.025   -11.929 -49.405 1.00 52.70  ? 45  PHE B O   1 
ATOM   1435 C  CB  . PHE B 1 45  ? 5.177   -10.032 -49.993 1.00 51.37  ? 45  PHE B CB  1 
ATOM   1436 C  CG  . PHE B 1 45  ? 5.431   -9.290  -48.707 1.00 52.09  ? 45  PHE B CG  1 
ATOM   1437 C  CD1 . PHE B 1 45  ? 6.703   -9.258  -48.142 1.00 54.84  ? 45  PHE B CD1 1 
ATOM   1438 C  CD2 . PHE B 1 45  ? 4.428   -8.532  -48.117 1.00 54.81  ? 45  PHE B CD2 1 
ATOM   1439 C  CE1 . PHE B 1 45  ? 6.946   -8.541  -46.966 1.00 55.62  ? 45  PHE B CE1 1 
ATOM   1440 C  CE2 . PHE B 1 45  ? 4.666   -7.831  -46.929 1.00 57.75  ? 45  PHE B CE2 1 
ATOM   1441 C  CZ  . PHE B 1 45  ? 5.928   -7.827  -46.370 1.00 55.15  ? 45  PHE B CZ  1 
ATOM   1442 N  N   . HIS B 1 46  ? 4.555   -13.320 -48.467 1.00 48.99  ? 46  HIS B N   1 
ATOM   1443 C  CA  . HIS B 1 46  ? 3.552   -14.161 -47.820 1.00 48.63  ? 46  HIS B CA  1 
ATOM   1444 C  C   . HIS B 1 46  ? 3.738   -14.451 -46.346 1.00 49.12  ? 46  HIS B C   1 
ATOM   1445 O  O   . HIS B 1 46  ? 4.872   -14.588 -45.883 1.00 47.48  ? 46  HIS B O   1 
ATOM   1446 C  CB  . HIS B 1 46  ? 3.463   -15.511 -48.565 1.00 50.70  ? 46  HIS B CB  1 
ATOM   1447 C  CG  . HIS B 1 46  ? 3.260   -15.395 -50.049 1.00 55.16  ? 46  HIS B CG  1 
ATOM   1448 N  ND1 . HIS B 1 46  ? 4.141   -15.973 -50.941 1.00 57.49  ? 46  HIS B ND1 1 
ATOM   1449 C  CD2 . HIS B 1 46  ? 2.292   -14.754 -50.745 1.00 57.80  ? 46  HIS B CD2 1 
ATOM   1450 C  CE1 . HIS B 1 46  ? 3.681   -15.676 -52.145 1.00 58.14  ? 46  HIS B CE1 1 
ATOM   1451 N  NE2 . HIS B 1 46  ? 2.577   -14.932 -52.074 1.00 58.56  ? 46  HIS B NE2 1 
ATOM   1452 N  N   . VAL B 1 47  ? 2.603   -14.644 -45.639 1.00 45.18  ? 47  VAL B N   1 
ATOM   1453 C  CA  . VAL B 1 47  ? 2.578   -15.090 -44.254 1.00 44.87  ? 47  VAL B CA  1 
ATOM   1454 C  C   . VAL B 1 47  ? 2.398   -16.608 -44.325 1.00 48.76  ? 47  VAL B C   1 
ATOM   1455 O  O   . VAL B 1 47  ? 1.410   -17.095 -44.876 1.00 49.63  ? 47  VAL B O   1 
ATOM   1456 C  CB  . VAL B 1 47  ? 1.515   -14.411 -43.321 1.00 49.35  ? 47  VAL B CB  1 
ATOM   1457 C  CG1 . VAL B 1 47  ? 1.618   -14.951 -41.887 1.00 47.61  ? 47  VAL B CG1 1 
ATOM   1458 C  CG2 . VAL B 1 47  ? 1.656   -12.888 -43.314 1.00 49.60  ? 47  VAL B CG2 1 
ATOM   1459 N  N   . HIS B 1 48  ? 3.383   -17.340 -43.794 1.00 45.83  ? 48  HIS B N   1 
ATOM   1460 C  CA  . HIS B 1 48  ? 3.421   -18.795 -43.702 1.00 45.63  ? 48  HIS B CA  1 
ATOM   1461 C  C   . HIS B 1 48  ? 2.944   -19.190 -42.303 1.00 49.69  ? 48  HIS B C   1 
ATOM   1462 O  O   . HIS B 1 48  ? 3.036   -18.384 -41.374 1.00 49.09  ? 48  HIS B O   1 
ATOM   1463 C  CB  . HIS B 1 48  ? 4.818   -19.334 -44.053 1.00 45.49  ? 48  HIS B CB  1 
ATOM   1464 C  CG  . HIS B 1 48  ? 5.151   -19.217 -45.514 1.00 49.10  ? 48  HIS B CG  1 
ATOM   1465 N  ND1 . HIS B 1 48  ? 5.360   -20.339 -46.298 1.00 51.68  ? 48  HIS B ND1 1 
ATOM   1466 C  CD2 . HIS B 1 48  ? 5.299   -18.113 -46.286 1.00 50.06  ? 48  HIS B CD2 1 
ATOM   1467 C  CE1 . HIS B 1 48  ? 5.643   -19.885 -47.509 1.00 51.85  ? 48  HIS B CE1 1 
ATOM   1468 N  NE2 . HIS B 1 48  ? 5.620   -18.551 -47.550 1.00 51.30  ? 48  HIS B NE2 1 
ATOM   1469 N  N   . GLU B 1 49  ? 2.361   -20.391 -42.179 1.00 48.44  ? 49  GLU B N   1 
ATOM   1470 C  CA  . GLU B 1 49  ? 1.678   -20.904 -40.980 1.00 48.94  ? 49  GLU B CA  1 
ATOM   1471 C  C   . GLU B 1 49  ? 2.501   -20.954 -39.694 1.00 52.73  ? 49  GLU B C   1 
ATOM   1472 O  O   . GLU B 1 49  ? 1.977   -20.587 -38.634 1.00 51.66  ? 49  GLU B O   1 
ATOM   1473 C  CB  . GLU B 1 49  ? 1.095   -22.296 -41.265 1.00 51.93  ? 49  GLU B CB  1 
ATOM   1474 C  CG  . GLU B 1 49  ? 0.064   -22.781 -40.254 1.00 60.70  ? 49  GLU B CG  1 
ATOM   1475 C  CD  . GLU B 1 49  ? -0.498  -24.166 -40.515 1.00 75.15  ? 49  GLU B CD  1 
ATOM   1476 O  OE1 . GLU B 1 49  ? -0.149  -24.776 -41.553 1.00 72.55  ? 49  GLU B OE1 1 
ATOM   1477 O  OE2 . GLU B 1 49  ? -1.292  -24.645 -39.675 1.00 63.43  ? 49  GLU B OE2 1 
ATOM   1478 N  N   . PHE B 1 50  ? 3.741   -21.472 -39.758 1.00 49.71  ? 50  PHE B N   1 
ATOM   1479 C  CA  . PHE B 1 50  ? 4.512   -21.654 -38.533 1.00 49.08  ? 50  PHE B CA  1 
ATOM   1480 C  C   . PHE B 1 50  ? 5.623   -20.659 -38.323 1.00 51.33  ? 50  PHE B C   1 
ATOM   1481 O  O   . PHE B 1 50  ? 6.343   -20.328 -39.260 1.00 49.73  ? 50  PHE B O   1 
ATOM   1482 C  CB  . PHE B 1 50  ? 5.064   -23.090 -38.446 1.00 52.12  ? 50  PHE B CB  1 
ATOM   1483 C  CG  . PHE B 1 50  ? 4.024   -24.166 -38.660 1.00 55.32  ? 50  PHE B CG  1 
ATOM   1484 C  CD1 . PHE B 1 50  ? 3.037   -24.403 -37.707 1.00 59.11  ? 50  PHE B CD1 1 
ATOM   1485 C  CD2 . PHE B 1 50  ? 4.023   -24.933 -39.820 1.00 58.40  ? 50  PHE B CD2 1 
ATOM   1486 C  CE1 . PHE B 1 50  ? 2.065   -25.387 -37.915 1.00 61.77  ? 50  PHE B CE1 1 
ATOM   1487 C  CE2 . PHE B 1 50  ? 3.053   -25.920 -40.026 1.00 62.85  ? 50  PHE B CE2 1 
ATOM   1488 C  CZ  . PHE B 1 50  ? 2.080   -26.139 -39.073 1.00 61.58  ? 50  PHE B CZ  1 
ATOM   1489 N  N   . GLY B 1 51  ? 5.776   -20.236 -37.065 1.00 49.26  ? 51  GLY B N   1 
ATOM   1490 C  CA  . GLY B 1 51  ? 6.856   -19.371 -36.598 1.00 47.72  ? 51  GLY B CA  1 
ATOM   1491 C  C   . GLY B 1 51  ? 8.029   -20.245 -36.211 1.00 52.60  ? 51  GLY B C   1 
ATOM   1492 O  O   . GLY B 1 51  ? 8.606   -20.089 -35.128 1.00 51.54  ? 51  GLY B O   1 
ATOM   1493 N  N   . ASP B 1 52  ? 8.341   -21.217 -37.085 1.00 49.56  ? 52  ASP B N   1 
ATOM   1494 C  CA  . ASP B 1 52  ? 9.400   -22.201 -36.904 1.00 50.85  ? 52  ASP B CA  1 
ATOM   1495 C  C   . ASP B 1 52  ? 10.553  -21.938 -37.884 1.00 55.47  ? 52  ASP B C   1 
ATOM   1496 O  O   . ASP B 1 52  ? 10.363  -22.047 -39.092 1.00 55.33  ? 52  ASP B O   1 
ATOM   1497 C  CB  . ASP B 1 52  ? 8.813   -23.622 -37.102 1.00 53.60  ? 52  ASP B CB  1 
ATOM   1498 C  CG  . ASP B 1 52  ? 9.706   -24.786 -36.692 1.00 58.96  ? 52  ASP B CG  1 
ATOM   1499 O  OD1 . ASP B 1 52  ? 10.939  -24.655 -36.790 1.00 58.49  ? 52  ASP B OD1 1 
ATOM   1500 O  OD2 . ASP B 1 52  ? 9.165   -25.837 -36.300 1.00 64.79  ? 52  ASP B OD2 1 
ATOM   1501 N  N   . ASN B 1 53  ? 11.743  -21.600 -37.362 1.00 53.14  ? 53  ASN B N   1 
ATOM   1502 C  CA  . ASN B 1 53  ? 12.924  -21.371 -38.206 1.00 54.00  ? 53  ASN B CA  1 
ATOM   1503 C  C   . ASN B 1 53  ? 14.068  -22.335 -37.809 1.00 59.53  ? 53  ASN B C   1 
ATOM   1504 O  O   . ASN B 1 53  ? 15.247  -21.989 -37.930 1.00 61.04  ? 53  ASN B O   1 
ATOM   1505 C  CB  . ASN B 1 53  ? 13.332  -19.884 -38.173 1.00 54.06  ? 53  ASN B CB  1 
ATOM   1506 C  CG  . ASN B 1 53  ? 14.388  -19.484 -39.182 1.00 73.79  ? 53  ASN B CG  1 
ATOM   1507 O  OD1 . ASN B 1 53  ? 14.149  -19.412 -40.387 1.00 68.07  ? 53  ASN B OD1 1 
ATOM   1508 N  ND2 . ASN B 1 53  ? 15.584  -19.203 -38.704 1.00 67.02  ? 53  ASN B ND2 1 
ATOM   1509 N  N   . THR B 1 54  ? 13.712  -23.554 -37.333 1.00 56.44  ? 54  THR B N   1 
ATOM   1510 C  CA  . THR B 1 54  ? 14.688  -24.565 -36.878 1.00 58.07  ? 54  THR B CA  1 
ATOM   1511 C  C   . THR B 1 54  ? 15.597  -25.062 -38.005 1.00 64.06  ? 54  THR B C   1 
ATOM   1512 O  O   . THR B 1 54  ? 16.779  -25.302 -37.770 1.00 65.40  ? 54  THR B O   1 
ATOM   1513 C  CB  . THR B 1 54  ? 14.017  -25.729 -36.132 1.00 65.57  ? 54  THR B CB  1 
ATOM   1514 O  OG1 . THR B 1 54  ? 13.029  -26.332 -36.971 1.00 67.61  ? 54  THR B OG1 1 
ATOM   1515 C  CG2 . THR B 1 54  ? 13.412  -25.305 -34.795 1.00 62.77  ? 54  THR B CG2 1 
ATOM   1516 N  N   . ALA B 1 55  ? 15.050  -25.198 -39.219 1.00 61.04  ? 55  ALA B N   1 
ATOM   1517 C  CA  . ALA B 1 55  ? 15.795  -25.625 -40.405 1.00 62.26  ? 55  ALA B CA  1 
ATOM   1518 C  C   . ALA B 1 55  ? 15.658  -24.549 -41.495 1.00 65.40  ? 55  ALA B C   1 
ATOM   1519 O  O   . ALA B 1 55  ? 15.346  -24.861 -42.646 1.00 66.81  ? 55  ALA B O   1 
ATOM   1520 C  CB  . ALA B 1 55  ? 15.258  -26.967 -40.901 1.00 64.51  ? 55  ALA B CB  1 
ATOM   1521 N  N   . GLY B 1 56  ? 15.868  -23.288 -41.113 1.00 58.82  ? 56  GLY B N   1 
ATOM   1522 C  CA  . GLY B 1 56  ? 15.744  -22.161 -42.031 1.00 57.24  ? 56  GLY B CA  1 
ATOM   1523 C  C   . GLY B 1 56  ? 14.305  -21.826 -42.385 1.00 59.22  ? 56  GLY B C   1 
ATOM   1524 O  O   . GLY B 1 56  ? 13.375  -22.238 -41.685 1.00 57.45  ? 56  GLY B O   1 
ATOM   1525 N  N   . CYS B 1 57  ? 14.114  -21.070 -43.476 1.00 55.49  ? 57  CYS B N   1 
ATOM   1526 C  CA  . CYS B 1 57  ? 12.803  -20.606 -43.942 1.00 55.20  ? 57  CYS B CA  1 
ATOM   1527 C  C   . CYS B 1 57  ? 11.838  -21.737 -44.358 1.00 58.47  ? 57  CYS B C   1 
ATOM   1528 O  O   . CYS B 1 57  ? 10.629  -21.520 -44.340 1.00 56.57  ? 57  CYS B O   1 
ATOM   1529 C  CB  . CYS B 1 57  ? 12.957  -19.565 -45.049 1.00 55.68  ? 57  CYS B CB  1 
ATOM   1530 S  SG  . CYS B 1 57  ? 13.721  -18.012 -44.504 1.00 59.36  ? 57  CYS B SG  1 
ATOM   1531 N  N   . THR B 1 58  ? 12.359  -22.931 -44.696 1.00 55.79  ? 58  THR B N   1 
ATOM   1532 C  CA  . THR B 1 58  ? 11.551  -24.089 -45.092 1.00 56.84  ? 58  THR B CA  1 
ATOM   1533 C  C   . THR B 1 58  ? 10.674  -24.615 -43.929 1.00 59.26  ? 58  THR B C   1 
ATOM   1534 O  O   . THR B 1 58  ? 9.564   -25.082 -44.182 1.00 58.37  ? 58  THR B O   1 
ATOM   1535 C  CB  . THR B 1 58  ? 12.445  -25.178 -45.724 1.00 69.55  ? 58  THR B CB  1 
ATOM   1536 O  OG1 . THR B 1 58  ? 13.241  -24.583 -46.752 1.00 71.52  ? 58  THR B OG1 1 
ATOM   1537 C  CG2 . THR B 1 58  ? 11.645  -26.333 -46.326 1.00 70.29  ? 58  THR B CG2 1 
ATOM   1538 N  N   . SER B 1 59  ? 11.152  -24.513 -42.666 1.00 54.85  ? 59  SER B N   1 
ATOM   1539 C  CA  . SER B 1 59  ? 10.402  -25.007 -41.504 1.00 54.55  ? 59  SER B CA  1 
ATOM   1540 C  C   . SER B 1 59  ? 9.143   -24.157 -41.159 1.00 57.24  ? 59  SER B C   1 
ATOM   1541 O  O   . SER B 1 59  ? 8.329   -24.571 -40.326 1.00 57.06  ? 59  SER B O   1 
ATOM   1542 C  CB  . SER B 1 59  ? 11.315  -25.193 -40.293 1.00 57.79  ? 59  SER B CB  1 
ATOM   1543 O  OG  . SER B 1 59  ? 12.209  -24.110 -40.113 1.00 66.71  ? 59  SER B OG  1 
ATOM   1544 N  N   . ALA B 1 60  ? 8.964   -23.007 -41.842 1.00 52.31  ? 60  ALA B N   1 
ATOM   1545 C  CA  . ALA B 1 60  ? 7.805   -22.128 -41.689 1.00 51.32  ? 60  ALA B CA  1 
ATOM   1546 C  C   . ALA B 1 60  ? 6.546   -22.813 -42.249 1.00 57.41  ? 60  ALA B C   1 
ATOM   1547 O  O   . ALA B 1 60  ? 5.429   -22.404 -41.942 1.00 57.39  ? 60  ALA B O   1 
ATOM   1548 C  CB  . ALA B 1 60  ? 8.052   -20.810 -42.406 1.00 51.07  ? 60  ALA B CB  1 
ATOM   1549 N  N   . GLY B 1 61  ? 6.754   -23.860 -43.049 1.00 55.47  ? 61  GLY B N   1 
ATOM   1550 C  CA  . GLY B 1 61  ? 5.696   -24.665 -43.640 1.00 55.91  ? 61  GLY B CA  1 
ATOM   1551 C  C   . GLY B 1 61  ? 4.966   -23.961 -44.757 1.00 58.74  ? 61  GLY B C   1 
ATOM   1552 O  O   . GLY B 1 61  ? 5.520   -23.049 -45.380 1.00 56.59  ? 61  GLY B O   1 
ATOM   1553 N  N   . PRO B 1 62  ? 3.704   -24.365 -45.030 1.00 57.69  ? 62  PRO B N   1 
ATOM   1554 C  CA  . PRO B 1 62  ? 2.964   -23.752 -46.148 1.00 57.62  ? 62  PRO B CA  1 
ATOM   1555 C  C   . PRO B 1 62  ? 2.417   -22.366 -45.824 1.00 60.69  ? 62  PRO B C   1 
ATOM   1556 O  O   . PRO B 1 62  ? 2.638   -21.863 -44.727 1.00 58.60  ? 62  PRO B O   1 
ATOM   1557 C  CB  . PRO B 1 62  ? 1.846   -24.760 -46.412 1.00 61.14  ? 62  PRO B CB  1 
ATOM   1558 C  CG  . PRO B 1 62  ? 1.585   -25.386 -45.085 1.00 65.67  ? 62  PRO B CG  1 
ATOM   1559 C  CD  . PRO B 1 62  ? 2.911   -25.430 -44.373 1.00 60.96  ? 62  PRO B CD  1 
ATOM   1560 N  N   . HIS B 1 63  ? 1.691   -21.755 -46.773 1.00 58.91  ? 63  HIS B N   1 
ATOM   1561 C  CA  . HIS B 1 63  ? 1.060   -20.446 -46.581 1.00 58.19  ? 63  HIS B CA  1 
ATOM   1562 C  C   . HIS B 1 63  ? 0.031   -20.526 -45.451 1.00 58.04  ? 63  HIS B C   1 
ATOM   1563 O  O   . HIS B 1 63  ? -0.618  -21.565 -45.303 1.00 59.03  ? 63  HIS B O   1 
ATOM   1564 C  CB  . HIS B 1 63  ? 0.323   -20.037 -47.860 1.00 60.76  ? 63  HIS B CB  1 
ATOM   1565 C  CG  . HIS B 1 63  ? 1.195   -19.570 -48.984 1.00 65.01  ? 63  HIS B CG  1 
ATOM   1566 N  ND1 . HIS B 1 63  ? 0.773   -18.572 -49.844 1.00 67.61  ? 63  HIS B ND1 1 
ATOM   1567 C  CD2 . HIS B 1 63  ? 2.413   -20.003 -49.382 1.00 67.34  ? 63  HIS B CD2 1 
ATOM   1568 C  CE1 . HIS B 1 63  ? 1.749   -18.418 -50.722 1.00 67.45  ? 63  HIS B CE1 1 
ATOM   1569 N  NE2 . HIS B 1 63  ? 2.759   -19.256 -50.482 1.00 67.73  ? 63  HIS B NE2 1 
ATOM   1570 N  N   . PHE B 1 64  ? -0.126  -19.441 -44.664 1.00 50.21  ? 64  PHE B N   1 
ATOM   1571 C  CA  . PHE B 1 64  ? -1.137  -19.418 -43.604 1.00 49.07  ? 64  PHE B CA  1 
ATOM   1572 C  C   . PHE B 1 64  ? -2.522  -19.383 -44.283 1.00 54.19  ? 64  PHE B C   1 
ATOM   1573 O  O   . PHE B 1 64  ? -2.883  -18.404 -44.949 1.00 54.04  ? 64  PHE B O   1 
ATOM   1574 C  CB  . PHE B 1 64  ? -0.929  -18.247 -42.634 1.00 49.02  ? 64  PHE B CB  1 
ATOM   1575 C  CG  . PHE B 1 64  ? -1.931  -18.176 -41.507 1.00 49.49  ? 64  PHE B CG  1 
ATOM   1576 C  CD1 . PHE B 1 64  ? -2.253  -19.310 -40.766 1.00 51.51  ? 64  PHE B CD1 1 
ATOM   1577 C  CD2 . PHE B 1 64  ? -2.526  -16.970 -41.161 1.00 50.11  ? 64  PHE B CD2 1 
ATOM   1578 C  CE1 . PHE B 1 64  ? -3.197  -19.245 -39.740 1.00 51.39  ? 64  PHE B CE1 1 
ATOM   1579 C  CE2 . PHE B 1 64  ? -3.446  -16.901 -40.113 1.00 51.50  ? 64  PHE B CE2 1 
ATOM   1580 C  CZ  . PHE B 1 64  ? -3.770  -18.038 -39.407 1.00 49.73  ? 64  PHE B CZ  1 
ATOM   1581 N  N   . ASN B 1 65  ? -3.226  -20.516 -44.203 1.00 51.92  ? 65  ASN B N   1 
ATOM   1582 C  CA  . ASN B 1 65  ? -4.517  -20.740 -44.859 1.00 52.81  ? 65  ASN B CA  1 
ATOM   1583 C  C   . ASN B 1 65  ? -5.488  -21.467 -43.893 1.00 59.66  ? 65  ASN B C   1 
ATOM   1584 O  O   . ASN B 1 65  ? -5.786  -22.654 -44.083 1.00 61.32  ? 65  ASN B O   1 
ATOM   1585 C  CB  . ASN B 1 65  ? -4.273  -21.538 -46.153 1.00 52.57  ? 65  ASN B CB  1 
ATOM   1586 C  CG  . ASN B 1 65  ? -5.462  -21.706 -47.071 1.00 71.54  ? 65  ASN B CG  1 
ATOM   1587 O  OD1 . ASN B 1 65  ? -6.419  -20.922 -47.066 1.00 64.99  ? 65  ASN B OD1 1 
ATOM   1588 N  ND2 . ASN B 1 65  ? -5.404  -22.727 -47.913 1.00 63.60  ? 65  ASN B ND2 1 
ATOM   1589 N  N   . PRO B 1 66  ? -5.994  -20.773 -42.842 1.00 56.67  ? 66  PRO B N   1 
ATOM   1590 C  CA  . PRO B 1 66  ? -6.896  -21.449 -41.889 1.00 58.53  ? 66  PRO B CA  1 
ATOM   1591 C  C   . PRO B 1 66  ? -8.289  -21.772 -42.440 1.00 66.70  ? 66  PRO B C   1 
ATOM   1592 O  O   . PRO B 1 66  ? -8.977  -22.617 -41.868 1.00 67.95  ? 66  PRO B O   1 
ATOM   1593 C  CB  . PRO B 1 66  ? -6.939  -20.496 -40.689 1.00 58.98  ? 66  PRO B CB  1 
ATOM   1594 C  CG  . PRO B 1 66  ? -6.667  -19.157 -41.272 1.00 62.30  ? 66  PRO B CG  1 
ATOM   1595 C  CD  . PRO B 1 66  ? -5.751  -19.367 -42.452 1.00 57.09  ? 66  PRO B CD  1 
ATOM   1596 N  N   . LEU B 1 67  ? -8.686  -21.120 -43.550 1.00 65.18  ? 67  LEU B N   1 
ATOM   1597 C  CA  . LEU B 1 67  ? -9.978  -21.321 -44.218 1.00 67.99  ? 67  LEU B CA  1 
ATOM   1598 C  C   . LEU B 1 67  ? -9.937  -22.352 -45.362 1.00 74.06  ? 67  LEU B C   1 
ATOM   1599 O  O   . LEU B 1 67  ? -10.986 -22.655 -45.935 1.00 76.04  ? 67  LEU B O   1 
ATOM   1600 C  CB  . LEU B 1 67  ? -10.566 -19.978 -44.700 1.00 68.36  ? 67  LEU B CB  1 
ATOM   1601 C  CG  . LEU B 1 67  ? -11.181 -19.076 -43.612 1.00 73.94  ? 67  LEU B CG  1 
ATOM   1602 C  CD1 . LEU B 1 67  ? -11.493 -17.703 -44.158 1.00 74.71  ? 67  LEU B CD1 1 
ATOM   1603 C  CD2 . LEU B 1 67  ? -12.457 -19.675 -43.035 1.00 79.26  ? 67  LEU B CD2 1 
ATOM   1604 N  N   . SER B 1 68  ? -8.738  -22.916 -45.662 1.00 70.37  ? 68  SER B N   1 
ATOM   1605 C  CA  . SER B 1 68  ? -8.474  -23.926 -46.703 1.00 71.75  ? 68  SER B CA  1 
ATOM   1606 C  C   . SER B 1 68  ? -9.017  -23.517 -48.081 1.00 77.38  ? 68  SER B C   1 
ATOM   1607 O  O   . SER B 1 68  ? -9.792  -24.248 -48.702 1.00 80.37  ? 68  SER B O   1 
ATOM   1608 C  CB  . SER B 1 68  ? -8.969  -25.308 -46.278 1.00 77.55  ? 68  SER B CB  1 
ATOM   1609 O  OG  . SER B 1 68  ? -8.188  -25.832 -45.216 1.00 86.92  ? 68  SER B OG  1 
ATOM   1610 N  N   . ARG B 1 69  ? -8.605  -22.330 -48.539 1.00 71.31  ? 69  ARG B N   1 
ATOM   1611 C  CA  . ARG B 1 69  ? -9.016  -21.746 -49.811 1.00 71.44  ? 69  ARG B CA  1 
ATOM   1612 C  C   . ARG B 1 69  ? -7.906  -21.882 -50.841 1.00 74.13  ? 69  ARG B C   1 
ATOM   1613 O  O   . ARG B 1 69  ? -6.786  -22.286 -50.503 1.00 72.62  ? 69  ARG B O   1 
ATOM   1614 C  CB  . ARG B 1 69  ? -9.364  -20.255 -49.618 1.00 70.53  ? 69  ARG B CB  1 
ATOM   1615 C  CG  . ARG B 1 69  ? -10.424 -19.971 -48.551 1.00 77.73  ? 69  ARG B CG  1 
ATOM   1616 C  CD  . ARG B 1 69  ? -11.827 -19.908 -49.112 1.00 88.78  ? 69  ARG B CD  1 
ATOM   1617 N  NE  . ARG B 1 69  ? -12.797 -19.485 -48.101 1.00 98.84  ? 69  ARG B NE  1 
ATOM   1618 C  CZ  . ARG B 1 69  ? -13.126 -18.220 -47.855 1.00 115.24 ? 69  ARG B CZ  1 
ATOM   1619 N  NH1 . ARG B 1 69  ? -12.563 -17.234 -48.544 1.00 103.37 ? 69  ARG B NH1 1 
ATOM   1620 N  NH2 . ARG B 1 69  ? -14.019 -17.931 -46.915 1.00 100.65 ? 69  ARG B NH2 1 
ATOM   1621 N  N   . LYS B 1 70  ? -8.210  -21.536 -52.100 1.00 69.98  ? 70  LYS B N   1 
ATOM   1622 C  CA  . LYS B 1 70  ? -7.232  -21.532 -53.181 1.00 69.45  ? 70  LYS B CA  1 
ATOM   1623 C  C   . LYS B 1 70  ? -6.385  -20.272 -53.023 1.00 69.58  ? 70  LYS B C   1 
ATOM   1624 O  O   . LYS B 1 70  ? -6.850  -19.282 -52.449 1.00 68.85  ? 70  LYS B O   1 
ATOM   1625 C  CB  . LYS B 1 70  ? -7.928  -21.508 -54.560 1.00 74.11  ? 70  LYS B CB  1 
ATOM   1626 C  CG  . LYS B 1 70  ? -8.235  -22.875 -55.145 1.00 92.07  ? 70  LYS B CG  1 
ATOM   1627 C  CD  . LYS B 1 70  ? -9.198  -22.744 -56.323 1.00 107.48 ? 70  LYS B CD  1 
ATOM   1628 C  CE  . LYS B 1 70  ? -9.345  -24.016 -57.124 1.00 123.85 ? 70  LYS B CE  1 
ATOM   1629 N  NZ  . LYS B 1 70  ? -8.229  -24.197 -58.092 1.00 132.07 ? 70  LYS B NZ  1 
ATOM   1630 N  N   . HIS B 1 71  ? -5.157  -20.316 -53.541 1.00 63.16  ? 71  HIS B N   1 
ATOM   1631 C  CA  . HIS B 1 71  ? -4.219  -19.202 -53.540 1.00 60.60  ? 71  HIS B CA  1 
ATOM   1632 C  C   . HIS B 1 71  ? -4.673  -18.122 -54.531 1.00 66.94  ? 71  HIS B C   1 
ATOM   1633 O  O   . HIS B 1 71  ? -5.128  -18.443 -55.633 1.00 68.54  ? 71  HIS B O   1 
ATOM   1634 C  CB  . HIS B 1 71  ? -2.811  -19.709 -53.888 1.00 60.16  ? 71  HIS B CB  1 
ATOM   1635 C  CG  . HIS B 1 71  ? -1.808  -18.619 -54.074 1.00 61.67  ? 71  HIS B CG  1 
ATOM   1636 N  ND1 . HIS B 1 71  ? -1.276  -17.946 -52.999 1.00 60.81  ? 71  HIS B ND1 1 
ATOM   1637 C  CD2 . HIS B 1 71  ? -1.319  -18.082 -55.216 1.00 63.91  ? 71  HIS B CD2 1 
ATOM   1638 C  CE1 . HIS B 1 71  ? -0.469  -17.034 -53.511 1.00 60.19  ? 71  HIS B CE1 1 
ATOM   1639 N  NE2 . HIS B 1 71  ? -0.454  -17.086 -54.842 1.00 62.20  ? 71  HIS B NE2 1 
ATOM   1640 N  N   . GLY B 1 72  ? -4.541  -16.862 -54.130 1.00 62.89  ? 72  GLY B N   1 
ATOM   1641 C  CA  . GLY B 1 72  ? -4.900  -15.720 -54.968 1.00 64.22  ? 72  GLY B CA  1 
ATOM   1642 C  C   . GLY B 1 72  ? -4.147  -14.464 -54.584 1.00 66.61  ? 72  GLY B C   1 
ATOM   1643 O  O   . GLY B 1 72  ? -3.228  -14.517 -53.768 1.00 63.47  ? 72  GLY B O   1 
ATOM   1644 N  N   . GLY B 1 73  ? -4.525  -13.341 -55.186 1.00 64.96  ? 73  GLY B N   1 
ATOM   1645 C  CA  . GLY B 1 73  ? -3.942  -12.042 -54.865 1.00 64.24  ? 73  GLY B CA  1 
ATOM   1646 C  C   . GLY B 1 73  ? -4.603  -11.437 -53.630 1.00 66.66  ? 73  GLY B C   1 
ATOM   1647 O  O   . GLY B 1 73  ? -5.651  -11.931 -53.194 1.00 66.40  ? 73  GLY B O   1 
ATOM   1648 N  N   . PRO B 1 74  ? -4.053  -10.340 -53.053 1.00 62.11  ? 74  PRO B N   1 
ATOM   1649 C  CA  . PRO B 1 74  ? -4.679  -9.761  -51.842 1.00 61.31  ? 74  PRO B CA  1 
ATOM   1650 C  C   . PRO B 1 74  ? -6.068  -9.153  -52.055 1.00 66.92  ? 74  PRO B C   1 
ATOM   1651 O  O   . PRO B 1 74  ? -6.889  -9.202  -51.138 1.00 65.36  ? 74  PRO B O   1 
ATOM   1652 C  CB  . PRO B 1 74  ? -3.659  -8.731  -51.350 1.00 62.21  ? 74  PRO B CB  1 
ATOM   1653 C  CG  . PRO B 1 74  ? -2.776  -8.453  -52.511 1.00 67.35  ? 74  PRO B CG  1 
ATOM   1654 C  CD  . PRO B 1 74  ? -2.810  -9.631  -53.428 1.00 63.15  ? 74  PRO B CD  1 
ATOM   1655 N  N   . LYS B 1 75  ? -6.348  -8.625  -53.264 1.00 66.01  ? 75  LYS B N   1 
ATOM   1656 C  CA  . LYS B 1 75  ? -7.656  -8.036  -53.612 1.00 68.43  ? 75  LYS B CA  1 
ATOM   1657 C  C   . LYS B 1 75  ? -8.713  -9.089  -54.009 1.00 73.81  ? 75  LYS B C   1 
ATOM   1658 O  O   . LYS B 1 75  ? -9.864  -8.721  -54.297 1.00 75.61  ? 75  LYS B O   1 
ATOM   1659 C  CB  . LYS B 1 75  ? -7.501  -6.993  -54.735 1.00 73.66  ? 75  LYS B CB  1 
ATOM   1660 C  CG  . LYS B 1 75  ? -6.899  -5.665  -54.287 1.00 93.35  ? 75  LYS B CG  1 
ATOM   1661 C  CD  . LYS B 1 75  ? -6.707  -4.725  -55.477 1.00 105.93 ? 75  LYS B CD  1 
ATOM   1662 C  CE  . LYS B 1 75  ? -6.268  -3.345  -55.055 1.00 115.74 ? 75  LYS B CE  1 
ATOM   1663 N  NZ  . LYS B 1 75  ? -6.033  -2.458  -56.225 1.00 124.07 ? 75  LYS B NZ  1 
ATOM   1664 N  N   . ASP B 1 76  ? -8.335  -10.385 -54.043 1.00 68.99  ? 76  ASP B N   1 
ATOM   1665 C  CA  . ASP B 1 76  ? -9.254  -11.470 -54.416 1.00 70.14  ? 76  ASP B CA  1 
ATOM   1666 C  C   . ASP B 1 76  ? -10.099 -11.984 -53.243 1.00 74.41  ? 76  ASP B C   1 
ATOM   1667 O  O   . ASP B 1 76  ? -9.643  -11.962 -52.097 1.00 71.15  ? 76  ASP B O   1 
ATOM   1668 C  CB  . ASP B 1 76  ? -8.486  -12.643 -55.054 1.00 70.96  ? 76  ASP B CB  1 
ATOM   1669 C  CG  . ASP B 1 76  ? -7.831  -12.339 -56.388 1.00 78.50  ? 76  ASP B CG  1 
ATOM   1670 O  OD1 . ASP B 1 76  ? -8.338  -11.459 -57.114 1.00 79.04  ? 76  ASP B OD1 1 
ATOM   1671 O  OD2 . ASP B 1 76  ? -6.816  -12.987 -56.709 1.00 85.12  ? 76  ASP B OD2 1 
ATOM   1672 N  N   . GLU B 1 77  ? -11.328 -12.467 -53.542 1.00 73.79  ? 77  GLU B N   1 
ATOM   1673 C  CA  . GLU B 1 77  ? -12.216 -13.055 -52.531 1.00 74.11  ? 77  GLU B CA  1 
ATOM   1674 C  C   . GLU B 1 77  ? -11.693 -14.448 -52.148 1.00 76.33  ? 77  GLU B C   1 
ATOM   1675 O  O   . GLU B 1 77  ? -11.732 -14.817 -50.973 1.00 76.25  ? 77  GLU B O   1 
ATOM   1676 C  CB  . GLU B 1 77  ? -13.680 -13.111 -53.020 1.00 78.43  ? 77  GLU B CB  1 
ATOM   1677 C  CG  . GLU B 1 77  ? -14.686 -13.548 -51.957 1.00 92.73  ? 77  GLU B CG  1 
ATOM   1678 C  CD  . GLU B 1 77  ? -14.807 -12.678 -50.716 1.00 118.78 ? 77  GLU B CD  1 
ATOM   1679 O  OE1 . GLU B 1 77  ? -15.712 -11.813 -50.686 1.00 124.38 ? 77  GLU B OE1 1 
ATOM   1680 O  OE2 . GLU B 1 77  ? -14.012 -12.873 -49.768 1.00 108.92 ? 77  GLU B OE2 1 
ATOM   1681 N  N   . GLU B 1 78  ? -11.189 -15.201 -53.144 1.00 72.25  ? 78  GLU B N   1 
ATOM   1682 C  CA  . GLU B 1 78  ? -10.588 -16.518 -52.963 1.00 70.99  ? 78  GLU B CA  1 
ATOM   1683 C  C   . GLU B 1 78  ? -9.073  -16.322 -52.816 1.00 70.09  ? 78  GLU B C   1 
ATOM   1684 O  O   . GLU B 1 78  ? -8.368  -16.067 -53.798 1.00 68.84  ? 78  GLU B O   1 
ATOM   1685 C  CB  . GLU B 1 78  ? -10.926 -17.460 -54.137 1.00 74.57  ? 78  GLU B CB  1 
ATOM   1686 C  CG  . GLU B 1 78  ? -10.555 -18.921 -53.901 1.00 84.42  ? 78  GLU B CG  1 
ATOM   1687 C  CD  . GLU B 1 78  ? -11.332 -19.723 -52.866 1.00 101.43 ? 78  GLU B CD  1 
ATOM   1688 O  OE1 . GLU B 1 78  ? -10.905 -20.864 -52.579 1.00 83.25  ? 78  GLU B OE1 1 
ATOM   1689 O  OE2 . GLU B 1 78  ? -12.365 -19.231 -52.353 1.00 98.68  ? 78  GLU B OE2 1 
ATOM   1690 N  N   . ARG B 1 79  ? -8.600  -16.382 -51.567 1.00 63.88  ? 79  ARG B N   1 
ATOM   1691 C  CA  . ARG B 1 79  ? -7.191  -16.201 -51.202 1.00 60.56  ? 79  ARG B CA  1 
ATOM   1692 C  C   . ARG B 1 79  ? -6.938  -16.812 -49.826 1.00 62.33  ? 79  ARG B C   1 
ATOM   1693 O  O   . ARG B 1 79  ? -7.866  -16.960 -49.017 1.00 61.54  ? 79  ARG B O   1 
ATOM   1694 C  CB  . ARG B 1 79  ? -6.820  -14.694 -51.169 1.00 58.26  ? 79  ARG B CB  1 
ATOM   1695 C  CG  . ARG B 1 79  ? -7.618  -13.882 -50.121 1.00 59.58  ? 79  ARG B CG  1 
ATOM   1696 C  CD  . ARG B 1 79  ? -7.020  -12.525 -49.825 1.00 52.94  ? 79  ARG B CD  1 
ATOM   1697 N  NE  . ARG B 1 79  ? -5.982  -12.580 -48.794 1.00 51.90  ? 79  ARG B NE  1 
ATOM   1698 C  CZ  . ARG B 1 79  ? -5.450  -11.503 -48.229 1.00 68.58  ? 79  ARG B CZ  1 
ATOM   1699 N  NH1 . ARG B 1 79  ? -5.860  -10.289 -48.582 1.00 57.46  ? 79  ARG B NH1 1 
ATOM   1700 N  NH2 . ARG B 1 79  ? -4.514  -11.628 -47.295 1.00 55.15  ? 79  ARG B NH2 1 
ATOM   1701 N  N   . HIS B 1 80  ? -5.674  -17.134 -49.550 1.00 57.58  ? 80  HIS B N   1 
ATOM   1702 C  CA  . HIS B 1 80  ? -5.256  -17.605 -48.230 1.00 55.83  ? 80  HIS B CA  1 
ATOM   1703 C  C   . HIS B 1 80  ? -5.201  -16.354 -47.347 1.00 57.11  ? 80  HIS B C   1 
ATOM   1704 O  O   . HIS B 1 80  ? -5.059  -15.245 -47.869 1.00 55.47  ? 80  HIS B O   1 
ATOM   1705 C  CB  . HIS B 1 80  ? -3.836  -18.204 -48.293 1.00 55.32  ? 80  HIS B CB  1 
ATOM   1706 C  CG  . HIS B 1 80  ? -3.636  -19.340 -49.254 1.00 59.82  ? 80  HIS B CG  1 
ATOM   1707 N  ND1 . HIS B 1 80  ? -2.377  -19.683 -49.694 1.00 61.27  ? 80  HIS B ND1 1 
ATOM   1708 C  CD2 . HIS B 1 80  ? -4.532  -20.190 -49.804 1.00 63.71  ? 80  HIS B CD2 1 
ATOM   1709 C  CE1 . HIS B 1 80  ? -2.539  -20.726 -50.488 1.00 62.33  ? 80  HIS B CE1 1 
ATOM   1710 N  NE2 . HIS B 1 80  ? -3.820  -21.063 -50.591 1.00 64.14  ? 80  HIS B NE2 1 
ATOM   1711 N  N   . VAL B 1 81  ? -5.256  -16.514 -46.020 1.00 54.05  ? 81  VAL B N   1 
ATOM   1712 C  CA  . VAL B 1 81  ? -5.076  -15.365 -45.130 1.00 53.57  ? 81  VAL B CA  1 
ATOM   1713 C  C   . VAL B 1 81  ? -3.669  -14.735 -45.372 1.00 54.86  ? 81  VAL B C   1 
ATOM   1714 O  O   . VAL B 1 81  ? -3.555  -13.514 -45.435 1.00 54.75  ? 81  VAL B O   1 
ATOM   1715 C  CB  . VAL B 1 81  ? -5.341  -15.715 -43.633 1.00 56.78  ? 81  VAL B CB  1 
ATOM   1716 C  CG1 . VAL B 1 81  ? -4.808  -14.630 -42.697 1.00 55.66  ? 81  VAL B CG1 1 
ATOM   1717 C  CG2 . VAL B 1 81  ? -6.834  -15.935 -43.386 1.00 57.85  ? 81  VAL B CG2 1 
ATOM   1718 N  N   . GLY B 1 82  ? -2.661  -15.571 -45.614 1.00 50.13  ? 82  GLY B N   1 
ATOM   1719 C  CA  . GLY B 1 82  ? -1.284  -15.126 -45.847 1.00 49.26  ? 82  GLY B CA  1 
ATOM   1720 C  C   . GLY B 1 82  ? -0.955  -14.563 -47.226 1.00 53.48  ? 82  GLY B C   1 
ATOM   1721 O  O   . GLY B 1 82  ? 0.177   -14.134 -47.450 1.00 51.35  ? 82  GLY B O   1 
ATOM   1722 N  N   . ASP B 1 83  ? -1.938  -14.519 -48.147 1.00 51.07  ? 83  ASP B N   1 
ATOM   1723 C  CA  . ASP B 1 83  ? -1.760  -14.023 -49.520 1.00 51.74  ? 83  ASP B CA  1 
ATOM   1724 C  C   . ASP B 1 83  ? -1.624  -12.501 -49.610 1.00 57.18  ? 83  ASP B C   1 
ATOM   1725 O  O   . ASP B 1 83  ? -2.585  -11.818 -49.990 1.00 57.67  ? 83  ASP B O   1 
ATOM   1726 C  CB  . ASP B 1 83  ? -2.895  -14.535 -50.426 1.00 54.36  ? 83  ASP B CB  1 
ATOM   1727 C  CG  . ASP B 1 83  ? -2.721  -15.971 -50.887 1.00 58.70  ? 83  ASP B CG  1 
ATOM   1728 O  OD1 . ASP B 1 83  ? -1.623  -16.547 -50.654 1.00 55.22  ? 83  ASP B OD1 1 
ATOM   1729 O  OD2 . ASP B 1 83  ? -3.679  -16.524 -51.475 1.00 60.50  ? 83  ASP B OD2 1 
ATOM   1730 N  N   . LEU B 1 84  ? -0.414  -11.973 -49.298 1.00 53.05  ? 84  LEU B N   1 
ATOM   1731 C  CA  . LEU B 1 84  ? -0.157  -10.529 -49.331 1.00 53.47  ? 84  LEU B CA  1 
ATOM   1732 C  C   . LEU B 1 84  ? 0.400   -10.033 -50.669 1.00 60.79  ? 84  LEU B C   1 
ATOM   1733 O  O   . LEU B 1 84  ? 0.786   -8.868  -50.782 1.00 62.21  ? 84  LEU B O   1 
ATOM   1734 C  CB  . LEU B 1 84  ? 0.721   -10.067 -48.152 1.00 52.41  ? 84  LEU B CB  1 
ATOM   1735 C  CG  . LEU B 1 84  ? 0.112   -10.181 -46.752 1.00 55.95  ? 84  LEU B CG  1 
ATOM   1736 C  CD1 . LEU B 1 84  ? 1.163   -9.935  -45.688 1.00 54.05  ? 84  LEU B CD1 1 
ATOM   1737 C  CD2 . LEU B 1 84  ? -1.087  -9.235  -46.583 1.00 59.31  ? 84  LEU B CD2 1 
ATOM   1738 N  N   . GLY B 1 85  ? 0.393   -10.904 -51.677 1.00 58.27  ? 85  GLY B N   1 
ATOM   1739 C  CA  . GLY B 1 85  ? 0.817   -10.572 -53.028 1.00 58.74  ? 85  GLY B CA  1 
ATOM   1740 C  C   . GLY B 1 85  ? 2.306   -10.399 -53.221 1.00 60.11  ? 85  GLY B C   1 
ATOM   1741 O  O   . GLY B 1 85  ? 3.093   -11.279 -52.871 1.00 57.01  ? 85  GLY B O   1 
ATOM   1742 N  N   . ASN B 1 86  ? 2.688   -9.262  -53.820 1.00 58.12  ? 86  ASN B N   1 
ATOM   1743 C  CA  . ASN B 1 86  ? 4.061   -8.942  -54.190 1.00 57.64  ? 86  ASN B CA  1 
ATOM   1744 C  C   . ASN B 1 86  ? 4.549   -7.624  -53.658 1.00 60.85  ? 86  ASN B C   1 
ATOM   1745 O  O   . ASN B 1 86  ? 3.767   -6.692  -53.447 1.00 61.87  ? 86  ASN B O   1 
ATOM   1746 C  CB  . ASN B 1 86  ? 4.194   -8.897  -55.732 1.00 57.82  ? 86  ASN B CB  1 
ATOM   1747 C  CG  . ASN B 1 86  ? 4.042   -10.224 -56.408 1.00 67.33  ? 86  ASN B CG  1 
ATOM   1748 O  OD1 . ASN B 1 86  ? 4.824   -11.137 -56.182 1.00 58.95  ? 86  ASN B OD1 1 
ATOM   1749 N  ND2 . ASN B 1 86  ? 3.042   -10.355 -57.263 1.00 65.12  ? 86  ASN B ND2 1 
ATOM   1750 N  N   . VAL B 1 87  ? 5.870   -7.551  -53.483 1.00 55.79  ? 87  VAL B N   1 
ATOM   1751 C  CA  . VAL B 1 87  ? 6.618   -6.349  -53.152 1.00 56.46  ? 87  VAL B CA  1 
ATOM   1752 C  C   . VAL B 1 87  ? 7.463   -6.043  -54.382 1.00 62.42  ? 87  VAL B C   1 
ATOM   1753 O  O   . VAL B 1 87  ? 7.898   -6.977  -55.060 1.00 62.40  ? 87  VAL B O   1 
ATOM   1754 C  CB  . VAL B 1 87  ? 7.433   -6.423  -51.830 1.00 59.16  ? 87  VAL B CB  1 
ATOM   1755 C  CG1 . VAL B 1 87  ? 6.494   -6.475  -50.627 1.00 57.40  ? 87  VAL B CG1 1 
ATOM   1756 C  CG2 . VAL B 1 87  ? 8.419   -7.595  -51.811 1.00 58.33  ? 87  VAL B CG2 1 
ATOM   1757 N  N   . THR B 1 88  ? 7.615   -4.766  -54.737 1.00 61.08  ? 88  THR B N   1 
ATOM   1758 C  CA  . THR B 1 88  ? 8.401   -4.427  -55.929 1.00 62.65  ? 88  THR B CA  1 
ATOM   1759 C  C   . THR B 1 88  ? 9.727   -3.777  -55.499 1.00 67.27  ? 88  THR B C   1 
ATOM   1760 O  O   . THR B 1 88  ? 9.733   -2.803  -54.738 1.00 67.09  ? 88  THR B O   1 
ATOM   1761 C  CB  . THR B 1 88  ? 7.588   -3.646  -56.999 1.00 72.82  ? 88  THR B CB  1 
ATOM   1762 O  OG1 . THR B 1 88  ? 8.434   -3.341  -58.118 1.00 76.46  ? 88  THR B OG1 1 
ATOM   1763 C  CG2 . THR B 1 88  ? 6.930   -2.374  -56.472 1.00 71.70  ? 88  THR B CG2 1 
ATOM   1764 N  N   . ALA B 1 89  ? 10.844  -4.384  -55.942 1.00 63.38  ? 89  ALA B N   1 
ATOM   1765 C  CA  . ALA B 1 89  ? 12.201  -3.918  -55.686 1.00 63.87  ? 89  ALA B CA  1 
ATOM   1766 C  C   . ALA B 1 89  ? 12.684  -3.096  -56.870 1.00 69.32  ? 89  ALA B C   1 
ATOM   1767 O  O   . ALA B 1 89  ? 12.492  -3.496  -58.024 1.00 69.13  ? 89  ALA B O   1 
ATOM   1768 C  CB  . ALA B 1 89  ? 13.134  -5.099  -55.455 1.00 63.70  ? 89  ALA B CB  1 
ATOM   1769 N  N   . ASP B 1 90  ? 13.324  -1.951  -56.585 1.00 68.00  ? 90  ASP B N   1 
ATOM   1770 C  CA  . ASP B 1 90  ? 13.866  -1.061  -57.614 1.00 71.20  ? 90  ASP B CA  1 
ATOM   1771 C  C   . ASP B 1 90  ? 15.161  -1.625  -58.259 1.00 76.92  ? 90  ASP B C   1 
ATOM   1772 O  O   . ASP B 1 90  ? 15.505  -2.790  -58.025 1.00 74.78  ? 90  ASP B O   1 
ATOM   1773 C  CB  . ASP B 1 90  ? 14.046  0.377   -57.060 1.00 74.19  ? 90  ASP B CB  1 
ATOM   1774 C  CG  . ASP B 1 90  ? 14.964  0.555   -55.859 1.00 79.06  ? 90  ASP B CG  1 
ATOM   1775 O  OD1 . ASP B 1 90  ? 15.936  -0.221  -55.726 1.00 77.98  ? 90  ASP B OD1 1 
ATOM   1776 O  OD2 . ASP B 1 90  ? 14.731  1.496   -55.072 1.00 85.36  ? 90  ASP B OD2 1 
ATOM   1777 N  N   . LYS B 1 91  ? 15.868  -0.803  -59.070 1.00 76.51  ? 91  LYS B N   1 
ATOM   1778 C  CA  . LYS B 1 91  ? 17.116  -1.196  -59.731 1.00 77.82  ? 91  LYS B CA  1 
ATOM   1779 C  C   . LYS B 1 91  ? 18.242  -1.493  -58.728 1.00 80.34  ? 91  LYS B C   1 
ATOM   1780 O  O   . LYS B 1 91  ? 19.057  -2.381  -58.978 1.00 79.89  ? 91  LYS B O   1 
ATOM   1781 C  CB  . LYS B 1 91  ? 17.548  -0.169  -60.805 1.00 83.86  ? 91  LYS B CB  1 
ATOM   1782 C  CG  . LYS B 1 91  ? 17.906  1.223   -60.276 1.00 97.62  ? 91  LYS B CG  1 
ATOM   1783 C  CD  . LYS B 1 91  ? 17.824  2.293   -61.351 1.00 109.08 ? 91  LYS B CD  1 
ATOM   1784 C  CE  . LYS B 1 91  ? 18.114  3.660   -60.784 1.00 118.71 ? 91  LYS B CE  1 
ATOM   1785 N  NZ  . LYS B 1 91  ? 17.658  4.743   -61.692 1.00 130.48 ? 91  LYS B NZ  1 
ATOM   1786 N  N   . ASP B 1 92  ? 18.251  -0.778  -57.583 1.00 75.84  ? 92  ASP B N   1 
ATOM   1787 C  CA  . ASP B 1 92  ? 19.243  -0.935  -56.515 1.00 74.83  ? 92  ASP B CA  1 
ATOM   1788 C  C   . ASP B 1 92  ? 18.873  -2.046  -55.510 1.00 73.27  ? 92  ASP B C   1 
ATOM   1789 O  O   . ASP B 1 92  ? 19.534  -2.203  -54.482 1.00 71.08  ? 92  ASP B O   1 
ATOM   1790 C  CB  . ASP B 1 92  ? 19.513  0.418   -55.816 1.00 78.28  ? 92  ASP B CB  1 
ATOM   1791 C  CG  . ASP B 1 92  ? 20.108  1.502   -56.712 1.00 92.84  ? 92  ASP B CG  1 
ATOM   1792 O  OD1 . ASP B 1 92  ? 20.838  1.154   -57.672 1.00 94.15  ? 92  ASP B OD1 1 
ATOM   1793 O  OD2 . ASP B 1 92  ? 19.857  2.697   -56.444 1.00 102.11 ? 92  ASP B OD2 1 
ATOM   1794 N  N   . GLY B 1 93  ? 17.849  -2.825  -55.852 1.00 67.53  ? 93  GLY B N   1 
ATOM   1795 C  CA  . GLY B 1 93  ? 17.367  -3.950  -55.060 1.00 63.92  ? 93  GLY B CA  1 
ATOM   1796 C  C   . GLY B 1 93  ? 16.649  -3.606  -53.770 1.00 63.16  ? 93  GLY B C   1 
ATOM   1797 O  O   . GLY B 1 93  ? 16.596  -4.442  -52.865 1.00 59.87  ? 93  GLY B O   1 
ATOM   1798 N  N   . VAL B 1 94  ? 16.066  -2.396  -53.683 1.00 60.35  ? 94  VAL B N   1 
ATOM   1799 C  CA  . VAL B 1 94  ? 15.340  -1.948  -52.487 1.00 59.11  ? 94  VAL B CA  1 
ATOM   1800 C  C   . VAL B 1 94  ? 13.821  -1.930  -52.733 1.00 64.85  ? 94  VAL B C   1 
ATOM   1801 O  O   . VAL B 1 94  ? 13.349  -1.235  -53.633 1.00 65.31  ? 94  VAL B O   1 
ATOM   1802 C  CB  . VAL B 1 94  ? 15.881  -0.599  -51.924 1.00 63.56  ? 94  VAL B CB  1 
ATOM   1803 C  CG1 . VAL B 1 94  ? 15.057  -0.116  -50.728 1.00 61.88  ? 94  VAL B CG1 1 
ATOM   1804 C  CG2 . VAL B 1 94  ? 17.357  -0.711  -51.546 1.00 63.71  ? 94  VAL B CG2 1 
ATOM   1805 N  N   . ALA B 1 95  ? 13.066  -2.696  -51.926 1.00 61.56  ? 95  ALA B N   1 
ATOM   1806 C  CA  . ALA B 1 95  ? 11.602  -2.740  -52.020 1.00 61.41  ? 95  ALA B CA  1 
ATOM   1807 C  C   . ALA B 1 95  ? 10.991  -1.959  -50.873 1.00 65.33  ? 95  ALA B C   1 
ATOM   1808 O  O   . ALA B 1 95  ? 11.186  -2.328  -49.720 1.00 64.30  ? 95  ALA B O   1 
ATOM   1809 C  CB  . ALA B 1 95  ? 11.102  -4.180  -52.009 1.00 60.32  ? 95  ALA B CB  1 
ATOM   1810 N  N   . ASP B 1 96  ? 10.294  -0.856  -51.188 1.00 64.62  ? 96  ASP B N   1 
ATOM   1811 C  CA  . ASP B 1 96  ? 9.612   -0.015  -50.206 1.00 65.16  ? 96  ASP B CA  1 
ATOM   1812 C  C   . ASP B 1 96  ? 8.183   -0.543  -50.033 1.00 67.93  ? 96  ASP B C   1 
ATOM   1813 O  O   . ASP B 1 96  ? 7.340   -0.373  -50.913 1.00 69.25  ? 96  ASP B O   1 
ATOM   1814 C  CB  . ASP B 1 96  ? 9.643   1.469   -50.623 1.00 70.21  ? 96  ASP B CB  1 
ATOM   1815 C  CG  . ASP B 1 96  ? 9.111   2.422   -49.567 1.00 87.54  ? 96  ASP B CG  1 
ATOM   1816 O  OD1 . ASP B 1 96  ? 9.794   2.605   -48.531 1.00 88.88  ? 96  ASP B OD1 1 
ATOM   1817 O  OD2 . ASP B 1 96  ? 8.015   2.991   -49.778 1.00 96.05  ? 96  ASP B OD2 1 
ATOM   1818 N  N   . VAL B 1 97  ? 7.935   -1.231  -48.912 1.00 62.41  ? 97  VAL B N   1 
ATOM   1819 C  CA  . VAL B 1 97  ? 6.647   -1.854  -48.596 1.00 60.69  ? 97  VAL B CA  1 
ATOM   1820 C  C   . VAL B 1 97  ? 5.690   -0.854  -47.950 1.00 65.44  ? 97  VAL B C   1 
ATOM   1821 O  O   . VAL B 1 97  ? 6.074   -0.130  -47.031 1.00 64.74  ? 97  VAL B O   1 
ATOM   1822 C  CB  . VAL B 1 97  ? 6.834   -3.129  -47.726 1.00 62.26  ? 97  VAL B CB  1 
ATOM   1823 C  CG1 . VAL B 1 97  ? 5.513   -3.875  -47.516 1.00 60.94  ? 97  VAL B CG1 1 
ATOM   1824 C  CG2 . VAL B 1 97  ? 7.885   -4.055  -48.327 1.00 61.51  ? 97  VAL B CG2 1 
ATOM   1825 N  N   . SER B 1 98  ? 4.442   -0.826  -48.454 1.00 63.36  ? 98  SER B N   1 
ATOM   1826 C  CA  . SER B 1 98  ? 3.324   -0.017  -47.975 1.00 64.78  ? 98  SER B CA  1 
ATOM   1827 C  C   . SER B 1 98  ? 2.029   -0.727  -48.422 1.00 68.27  ? 98  SER B C   1 
ATOM   1828 O  O   . SER B 1 98  ? 1.600   -0.589  -49.573 1.00 68.50  ? 98  SER B O   1 
ATOM   1829 C  CB  . SER B 1 98  ? 3.411   1.410   -48.513 1.00 72.26  ? 98  SER B CB  1 
ATOM   1830 O  OG  . SER B 1 98  ? 2.897   2.327   -47.561 1.00 85.54  ? 98  SER B OG  1 
ATOM   1831 N  N   . ILE B 1 99  ? 1.469   -1.562  -47.520 1.00 63.13  ? 99  ILE B N   1 
ATOM   1832 C  CA  . ILE B 1 99  ? 0.282   -2.398  -47.755 1.00 62.22  ? 99  ILE B CA  1 
ATOM   1833 C  C   . ILE B 1 99  ? -0.764  -2.204  -46.643 1.00 65.36  ? 99  ILE B C   1 
ATOM   1834 O  O   . ILE B 1 99  ? -0.415  -2.089  -45.467 1.00 63.54  ? 99  ILE B O   1 
ATOM   1835 C  CB  . ILE B 1 99  ? 0.721   -3.907  -47.861 1.00 63.37  ? 99  ILE B CB  1 
ATOM   1836 C  CG1 . ILE B 1 99  ? 1.584   -4.176  -49.114 1.00 64.55  ? 99  ILE B CG1 1 
ATOM   1837 C  CG2 . ILE B 1 99  ? -0.464  -4.884  -47.799 1.00 63.64  ? 99  ILE B CG2 1 
ATOM   1838 C  CD1 . ILE B 1 99  ? 2.411   -5.501  -49.087 1.00 71.64  ? 99  ILE B CD1 1 
ATOM   1839 N  N   . GLU B 1 100 ? -2.044  -2.197  -47.023 1.00 62.38  ? 100 GLU B N   1 
ATOM   1840 C  CA  . GLU B 1 100 ? -3.159  -2.164  -46.089 1.00 62.30  ? 100 GLU B CA  1 
ATOM   1841 C  C   . GLU B 1 100 ? -3.972  -3.416  -46.418 1.00 63.70  ? 100 GLU B C   1 
ATOM   1842 O  O   . GLU B 1 100 ? -4.318  -3.632  -47.587 1.00 63.81  ? 100 GLU B O   1 
ATOM   1843 C  CB  . GLU B 1 100 ? -3.979  -0.876  -46.234 1.00 66.49  ? 100 GLU B CB  1 
ATOM   1844 C  CG  . GLU B 1 100 ? -4.707  -0.479  -44.964 1.00 78.04  ? 100 GLU B CG  1 
ATOM   1845 C  CD  . GLU B 1 100 ? -5.490  0.811   -45.099 1.00 102.43 ? 100 GLU B CD  1 
ATOM   1846 O  OE1 . GLU B 1 100 ? -4.887  1.893   -44.918 1.00 97.63  ? 100 GLU B OE1 1 
ATOM   1847 O  OE2 . GLU B 1 100 ? -6.705  0.741   -45.399 1.00 97.77  ? 100 GLU B OE2 1 
ATOM   1848 N  N   . ASP B 1 101 ? -4.173  -4.293  -45.418 1.00 57.89  ? 101 ASP B N   1 
ATOM   1849 C  CA  . ASP B 1 101 ? -4.890  -5.554  -45.612 1.00 56.70  ? 101 ASP B CA  1 
ATOM   1850 C  C   . ASP B 1 101 ? -5.948  -5.810  -44.536 1.00 60.11  ? 101 ASP B C   1 
ATOM   1851 O  O   . ASP B 1 101 ? -5.662  -5.684  -43.341 1.00 59.34  ? 101 ASP B O   1 
ATOM   1852 C  CB  . ASP B 1 101 ? -3.903  -6.728  -45.715 1.00 56.06  ? 101 ASP B CB  1 
ATOM   1853 C  CG  . ASP B 1 101 ? -4.521  -7.972  -46.314 1.00 62.54  ? 101 ASP B CG  1 
ATOM   1854 O  OD1 . ASP B 1 101 ? -4.694  -8.009  -47.554 1.00 64.41  ? 101 ASP B OD1 1 
ATOM   1855 O  OD2 . ASP B 1 101 ? -4.843  -8.904  -45.546 1.00 64.11  ? 101 ASP B OD2 1 
ATOM   1856 N  N   . SER B 1 102 ? -7.161  -6.197  -44.969 1.00 56.64  ? 102 SER B N   1 
ATOM   1857 C  CA  . SER B 1 102 ? -8.301  -6.465  -44.081 1.00 58.30  ? 102 SER B CA  1 
ATOM   1858 C  C   . SER B 1 102 ? -8.562  -7.952  -43.798 1.00 61.80  ? 102 SER B C   1 
ATOM   1859 O  O   . SER B 1 102 ? -9.519  -8.269  -43.094 1.00 62.21  ? 102 SER B O   1 
ATOM   1860 C  CB  . SER B 1 102 ? -9.565  -5.800  -44.624 1.00 63.85  ? 102 SER B CB  1 
ATOM   1861 O  OG  . SER B 1 102 ? -9.470  -4.391  -44.515 1.00 72.87  ? 102 SER B OG  1 
ATOM   1862 N  N   . VAL B 1 103 ? -7.749  -8.859  -44.372 1.00 57.01  ? 103 VAL B N   1 
ATOM   1863 C  CA  . VAL B 1 103 ? -7.905  -10.302 -44.156 1.00 55.52  ? 103 VAL B CA  1 
ATOM   1864 C  C   . VAL B 1 103 ? -6.987  -10.760 -43.015 1.00 57.61  ? 103 VAL B C   1 
ATOM   1865 O  O   . VAL B 1 103 ? -7.428  -11.501 -42.141 1.00 57.63  ? 103 VAL B O   1 
ATOM   1866 C  CB  . VAL B 1 103 ? -7.762  -11.122 -45.464 1.00 58.63  ? 103 VAL B CB  1 
ATOM   1867 C  CG1 . VAL B 1 103 ? -7.656  -12.617 -45.177 1.00 58.05  ? 103 VAL B CG1 1 
ATOM   1868 C  CG2 . VAL B 1 103 ? -8.944  -10.848 -46.397 1.00 59.81  ? 103 VAL B CG2 1 
ATOM   1869 N  N   . ILE B 1 104 ? -5.736  -10.286 -43.000 1.00 53.01  ? 104 ILE B N   1 
ATOM   1870 C  CA  . ILE B 1 104 ? -4.798  -10.579 -41.908 1.00 51.29  ? 104 ILE B CA  1 
ATOM   1871 C  C   . ILE B 1 104 ? -5.225  -9.789  -40.670 1.00 53.74  ? 104 ILE B C   1 
ATOM   1872 O  O   . ILE B 1 104 ? -5.881  -8.752  -40.796 1.00 53.21  ? 104 ILE B O   1 
ATOM   1873 C  CB  . ILE B 1 104 ? -3.323  -10.287 -42.275 1.00 53.54  ? 104 ILE B CB  1 
ATOM   1874 C  CG1 . ILE B 1 104 ? -3.095  -8.794  -42.653 1.00 54.36  ? 104 ILE B CG1 1 
ATOM   1875 C  CG2 . ILE B 1 104 ? -2.820  -11.250 -43.357 1.00 54.50  ? 104 ILE B CG2 1 
ATOM   1876 C  CD1 . ILE B 1 104 ? -1.635  -8.290  -42.497 1.00 51.97  ? 104 ILE B CD1 1 
ATOM   1877 N  N   . SER B 1 105 ? -4.843  -10.273 -39.483 1.00 48.58  ? 105 SER B N   1 
ATOM   1878 C  CA  . SER B 1 105 ? -5.141  -9.603  -38.229 1.00 48.74  ? 105 SER B CA  1 
ATOM   1879 C  C   . SER B 1 105 ? -4.021  -9.818  -37.237 1.00 51.39  ? 105 SER B C   1 
ATOM   1880 O  O   . SER B 1 105 ? -3.238  -10.755 -37.382 1.00 49.85  ? 105 SER B O   1 
ATOM   1881 C  CB  . SER B 1 105 ? -6.459  -10.102 -37.647 1.00 51.31  ? 105 SER B CB  1 
ATOM   1882 O  OG  . SER B 1 105 ? -6.870  -9.281  -36.568 1.00 53.08  ? 105 SER B OG  1 
ATOM   1883 N  N   . LEU B 1 106 ? -3.936  -8.938  -36.241 1.00 49.46  ? 106 LEU B N   1 
ATOM   1884 C  CA  . LEU B 1 106 ? -2.962  -9.035  -35.162 1.00 48.58  ? 106 LEU B CA  1 
ATOM   1885 C  C   . LEU B 1 106 ? -3.615  -9.624  -33.877 1.00 55.51  ? 106 LEU B C   1 
ATOM   1886 O  O   . LEU B 1 106 ? -2.982  -9.659  -32.826 1.00 55.22  ? 106 LEU B O   1 
ATOM   1887 C  CB  . LEU B 1 106 ? -2.276  -7.679  -34.917 1.00 48.57  ? 106 LEU B CB  1 
ATOM   1888 C  CG  . LEU B 1 106 ? -1.513  -7.050  -36.109 1.00 52.30  ? 106 LEU B CG  1 
ATOM   1889 C  CD1 . LEU B 1 106 ? -0.816  -5.777  -35.692 1.00 52.48  ? 106 LEU B CD1 1 
ATOM   1890 C  CD2 . LEU B 1 106 ? -0.501  -8.027  -36.734 1.00 52.22  ? 106 LEU B CD2 1 
ATOM   1891 N  N   . SER B 1 107 ? -4.868  -10.134 -33.993 1.00 53.65  ? 107 SER B N   1 
ATOM   1892 C  CA  . SER B 1 107 ? -5.633  -10.796 -32.917 1.00 54.72  ? 107 SER B CA  1 
ATOM   1893 C  C   . SER B 1 107 ? -6.699  -11.749 -33.516 1.00 61.27  ? 107 SER B C   1 
ATOM   1894 O  O   . SER B 1 107 ? -6.941  -11.701 -34.722 1.00 59.27  ? 107 SER B O   1 
ATOM   1895 C  CB  . SER B 1 107 ? -6.276  -9.772  -31.981 1.00 58.23  ? 107 SER B CB  1 
ATOM   1896 O  OG  . SER B 1 107 ? -6.996  -8.758  -32.660 1.00 62.37  ? 107 SER B OG  1 
ATOM   1897 N  N   . GLY B 1 108 ? -7.269  -12.630 -32.682 1.00 61.64  ? 108 GLY B N   1 
ATOM   1898 C  CA  . GLY B 1 108 ? -8.315  -13.578 -33.076 1.00 63.90  ? 108 GLY B CA  1 
ATOM   1899 C  C   . GLY B 1 108 ? -7.915  -14.727 -33.992 1.00 70.17  ? 108 GLY B C   1 
ATOM   1900 O  O   . GLY B 1 108 ? -6.804  -15.255 -33.884 1.00 68.93  ? 108 GLY B O   1 
ATOM   1901 N  N   . ASP B 1 109 ? -8.845  -15.134 -34.890 1.00 68.52  ? 109 ASP B N   1 
ATOM   1902 C  CA  . ASP B 1 109 ? -8.719  -16.256 -35.837 1.00 68.49  ? 109 ASP B CA  1 
ATOM   1903 C  C   . ASP B 1 109 ? -7.648  -16.088 -36.908 1.00 69.65  ? 109 ASP B C   1 
ATOM   1904 O  O   . ASP B 1 109 ? -6.919  -17.039 -37.202 1.00 69.14  ? 109 ASP B O   1 
ATOM   1905 C  CB  . ASP B 1 109 ? -10.072 -16.557 -36.517 1.00 72.77  ? 109 ASP B CB  1 
ATOM   1906 C  CG  . ASP B 1 109 ? -11.035 -17.369 -35.670 1.00 86.50  ? 109 ASP B CG  1 
ATOM   1907 O  OD1 . ASP B 1 109 ? -11.340 -18.524 -36.058 1.00 88.44  ? 109 ASP B OD1 1 
ATOM   1908 O  OD2 . ASP B 1 109 ? -11.487 -16.852 -34.623 1.00 90.85  ? 109 ASP B OD2 1 
ATOM   1909 N  N   . HIS B 1 110 ? -7.595  -14.906 -37.534 1.00 63.93  ? 110 HIS B N   1 
ATOM   1910 C  CA  . HIS B 1 110 ? -6.645  -14.616 -38.605 1.00 61.68  ? 110 HIS B CA  1 
ATOM   1911 C  C   . HIS B 1 110 ? -5.361  -13.956 -38.059 1.00 60.36  ? 110 HIS B C   1 
ATOM   1912 O  O   . HIS B 1 110 ? -4.666  -13.273 -38.821 1.00 59.77  ? 110 HIS B O   1 
ATOM   1913 C  CB  . HIS B 1 110 ? -7.318  -13.757 -39.710 1.00 63.54  ? 110 HIS B CB  1 
ATOM   1914 C  CG  . HIS B 1 110 ? -8.461  -14.412 -40.435 1.00 68.92  ? 110 HIS B CG  1 
ATOM   1915 N  ND1 . HIS B 1 110 ? -9.248  -13.697 -41.332 1.00 72.19  ? 110 HIS B ND1 1 
ATOM   1916 C  CD2 . HIS B 1 110 ? -8.921  -15.687 -40.380 1.00 71.66  ? 110 HIS B CD2 1 
ATOM   1917 C  CE1 . HIS B 1 110 ? -10.149 -14.553 -41.787 1.00 72.90  ? 110 HIS B CE1 1 
ATOM   1918 N  NE2 . HIS B 1 110 ? -9.996  -15.761 -41.242 1.00 73.01  ? 110 HIS B NE2 1 
ATOM   1919 N  N   . CYS B 1 111 ? -5.045  -14.174 -36.746 1.00 53.63  ? 111 CYS B N   1 
ATOM   1920 C  CA  . CYS B 1 111 ? -3.860  -13.614 -36.076 1.00 51.19  ? 111 CYS B CA  1 
ATOM   1921 C  C   . CYS B 1 111 ? -2.549  -14.127 -36.674 1.00 50.90  ? 111 CYS B C   1 
ATOM   1922 O  O   . CYS B 1 111 ? -2.340  -15.338 -36.741 1.00 50.43  ? 111 CYS B O   1 
ATOM   1923 C  CB  . CYS B 1 111 ? -3.908  -13.832 -34.572 1.00 51.48  ? 111 CYS B CB  1 
ATOM   1924 S  SG  . CYS B 1 111 ? -2.529  -13.068 -33.683 1.00 54.13  ? 111 CYS B SG  1 
ATOM   1925 N  N   . ILE B 1 112 ? -1.685  -13.203 -37.121 1.00 45.55  ? 112 ILE B N   1 
ATOM   1926 C  CA  . ILE B 1 112 ? -0.403  -13.535 -37.771 1.00 43.12  ? 112 ILE B CA  1 
ATOM   1927 C  C   . ILE B 1 112 ? 0.808   -13.421 -36.802 1.00 44.81  ? 112 ILE B C   1 
ATOM   1928 O  O   . ILE B 1 112 ? 1.921   -13.783 -37.191 1.00 43.05  ? 112 ILE B O   1 
ATOM   1929 C  CB  . ILE B 1 112 ? -0.191  -12.744 -39.095 1.00 45.64  ? 112 ILE B CB  1 
ATOM   1930 C  CG1 . ILE B 1 112 ? -0.021  -11.223 -38.838 1.00 45.23  ? 112 ILE B CG1 1 
ATOM   1931 C  CG2 . ILE B 1 112 ? -1.327  -13.056 -40.137 1.00 48.69  ? 112 ILE B CG2 1 
ATOM   1932 C  CD1 . ILE B 1 112 ? 0.397   -10.397 -40.081 1.00 46.16  ? 112 ILE B CD1 1 
ATOM   1933 N  N   . ILE B 1 113 ? 0.594   -12.941 -35.547 1.00 43.00  ? 113 ILE B N   1 
ATOM   1934 C  CA  . ILE B 1 113 ? 1.663   -12.873 -34.527 1.00 41.93  ? 113 ILE B CA  1 
ATOM   1935 C  C   . ILE B 1 113 ? 2.100   -14.314 -34.205 1.00 45.18  ? 113 ILE B C   1 
ATOM   1936 O  O   . ILE B 1 113 ? 1.256   -15.180 -33.979 1.00 44.13  ? 113 ILE B O   1 
ATOM   1937 C  CB  . ILE B 1 113 ? 1.237   -12.065 -33.246 1.00 45.61  ? 113 ILE B CB  1 
ATOM   1938 C  CG1 . ILE B 1 113 ? 1.020   -10.561 -33.592 1.00 46.74  ? 113 ILE B CG1 1 
ATOM   1939 C  CG2 . ILE B 1 113 ? 2.276   -12.220 -32.117 1.00 45.48  ? 113 ILE B CG2 1 
ATOM   1940 C  CD1 . ILE B 1 113 ? 0.309   -9.697  -32.524 1.00 52.34  ? 113 ILE B CD1 1 
ATOM   1941 N  N   . GLY B 1 114 ? 3.410   -14.551 -34.220 1.00 43.45  ? 114 GLY B N   1 
ATOM   1942 C  CA  . GLY B 1 114 ? 3.986   -15.864 -33.957 1.00 43.19  ? 114 GLY B CA  1 
ATOM   1943 C  C   . GLY B 1 114 ? 4.057   -16.723 -35.204 1.00 44.67  ? 114 GLY B C   1 
ATOM   1944 O  O   . GLY B 1 114 ? 4.388   -17.905 -35.119 1.00 43.72  ? 114 GLY B O   1 
ATOM   1945 N  N   . ARG B 1 115 ? 3.716   -16.152 -36.371 1.00 42.03  ? 115 ARG B N   1 
ATOM   1946 C  CA  . ARG B 1 115 ? 3.815   -16.852 -37.654 1.00 41.68  ? 115 ARG B CA  1 
ATOM   1947 C  C   . ARG B 1 115 ? 5.011   -16.249 -38.406 1.00 44.29  ? 115 ARG B C   1 
ATOM   1948 O  O   . ARG B 1 115 ? 5.683   -15.366 -37.859 1.00 42.61  ? 115 ARG B O   1 
ATOM   1949 C  CB  . ARG B 1 115 ? 2.466   -16.837 -38.436 1.00 43.79  ? 115 ARG B CB  1 
ATOM   1950 C  CG  . ARG B 1 115 ? 1.322   -17.436 -37.583 1.00 51.20  ? 115 ARG B CG  1 
ATOM   1951 C  CD  . ARG B 1 115 ? 0.073   -17.796 -38.354 1.00 52.48  ? 115 ARG B CD  1 
ATOM   1952 N  NE  . ARG B 1 115 ? -1.030  -18.150 -37.448 1.00 48.53  ? 115 ARG B NE  1 
ATOM   1953 C  CZ  . ARG B 1 115 ? -1.337  -19.388 -37.065 1.00 53.32  ? 115 ARG B CZ  1 
ATOM   1954 N  NH1 . ARG B 1 115 ? -0.639  -20.423 -37.514 1.00 47.39  ? 115 ARG B NH1 1 
ATOM   1955 N  NH2 . ARG B 1 115 ? -2.368  -19.604 -36.265 1.00 48.95  ? 115 ARG B NH2 1 
ATOM   1956 N  N   . THR B 1 116 ? 5.342   -16.769 -39.585 1.00 41.77  ? 116 THR B N   1 
ATOM   1957 C  CA  . THR B 1 116 ? 6.509   -16.301 -40.344 1.00 42.28  ? 116 THR B CA  1 
ATOM   1958 C  C   . THR B 1 116 ? 6.121   -15.521 -41.602 1.00 48.09  ? 116 THR B C   1 
ATOM   1959 O  O   . THR B 1 116 ? 5.297   -15.986 -42.387 1.00 50.44  ? 116 THR B O   1 
ATOM   1960 C  CB  . THR B 1 116 ? 7.417   -17.502 -40.698 1.00 48.48  ? 116 THR B CB  1 
ATOM   1961 O  OG1 . THR B 1 116 ? 7.874   -18.125 -39.505 1.00 45.72  ? 116 THR B OG1 1 
ATOM   1962 C  CG2 . THR B 1 116 ? 8.632   -17.123 -41.554 1.00 46.62  ? 116 THR B CG2 1 
ATOM   1963 N  N   . LEU B 1 117 ? 6.746   -14.354 -41.802 1.00 43.18  ? 117 LEU B N   1 
ATOM   1964 C  CA  . LEU B 1 117 ? 6.610   -13.571 -43.023 1.00 43.32  ? 117 LEU B CA  1 
ATOM   1965 C  C   . LEU B 1 117 ? 7.811   -13.983 -43.874 1.00 46.26  ? 117 LEU B C   1 
ATOM   1966 O  O   . LEU B 1 117 ? 8.930   -14.054 -43.358 1.00 45.16  ? 117 LEU B O   1 
ATOM   1967 C  CB  . LEU B 1 117 ? 6.647   -12.064 -42.720 1.00 43.54  ? 117 LEU B CB  1 
ATOM   1968 C  CG  . LEU B 1 117 ? 6.572   -11.093 -43.902 1.00 48.35  ? 117 LEU B CG  1 
ATOM   1969 C  CD1 . LEU B 1 117 ? 5.188   -11.159 -44.622 1.00 49.04  ? 117 LEU B CD1 1 
ATOM   1970 C  CD2 . LEU B 1 117 ? 6.865   -9.694  -43.441 1.00 49.13  ? 117 LEU B CD2 1 
ATOM   1971 N  N   . VAL B 1 118 ? 7.573   -14.309 -45.151 1.00 43.96  ? 118 VAL B N   1 
ATOM   1972 C  CA  . VAL B 1 118 ? 8.610   -14.749 -46.093 1.00 44.29  ? 118 VAL B CA  1 
ATOM   1973 C  C   . VAL B 1 118 ? 8.601   -13.855 -47.346 1.00 48.74  ? 118 VAL B C   1 
ATOM   1974 O  O   . VAL B 1 118 ? 7.527   -13.555 -47.875 1.00 46.64  ? 118 VAL B O   1 
ATOM   1975 C  CB  . VAL B 1 118 ? 8.399   -16.243 -46.512 1.00 48.85  ? 118 VAL B CB  1 
ATOM   1976 C  CG1 . VAL B 1 118 ? 9.390   -16.679 -47.597 1.00 49.70  ? 118 VAL B CG1 1 
ATOM   1977 C  CG2 . VAL B 1 118 ? 8.467   -17.189 -45.322 1.00 48.12  ? 118 VAL B CG2 1 
ATOM   1978 N  N   . VAL B 1 119 ? 9.801   -13.448 -47.814 1.00 46.46  ? 119 VAL B N   1 
ATOM   1979 C  CA  . VAL B 1 119 ? 9.994   -12.746 -49.083 1.00 48.44  ? 119 VAL B CA  1 
ATOM   1980 C  C   . VAL B 1 119 ? 10.576  -13.800 -50.055 1.00 53.29  ? 119 VAL B C   1 
ATOM   1981 O  O   . VAL B 1 119 ? 11.547  -14.481 -49.719 1.00 54.03  ? 119 VAL B O   1 
ATOM   1982 C  CB  . VAL B 1 119 ? 10.787  -11.407 -49.003 1.00 53.01  ? 119 VAL B CB  1 
ATOM   1983 C  CG1 . VAL B 1 119 ? 12.167  -11.582 -48.366 1.00 52.73  ? 119 VAL B CG1 1 
ATOM   1984 C  CG2 . VAL B 1 119 ? 10.894  -10.746 -50.379 1.00 53.99  ? 119 VAL B CG2 1 
ATOM   1985 N  N   . HIS B 1 120 ? 9.914   -13.996 -51.202 1.00 50.81  ? 120 HIS B N   1 
ATOM   1986 C  CA  . HIS B 1 120 ? 10.230  -15.040 -52.170 1.00 51.75  ? 120 HIS B CA  1 
ATOM   1987 C  C   . HIS B 1 120 ? 11.152  -14.629 -53.330 1.00 56.58  ? 120 HIS B C   1 
ATOM   1988 O  O   . HIS B 1 120 ? 11.299  -13.445 -53.641 1.00 55.88  ? 120 HIS B O   1 
ATOM   1989 C  CB  . HIS B 1 120 ? 8.934   -15.659 -52.717 1.00 52.59  ? 120 HIS B CB  1 
ATOM   1990 C  CG  . HIS B 1 120 ? 8.226   -16.507 -51.709 1.00 55.06  ? 120 HIS B CG  1 
ATOM   1991 N  ND1 . HIS B 1 120 ? 8.446   -17.870 -51.629 1.00 57.08  ? 120 HIS B ND1 1 
ATOM   1992 C  CD2 . HIS B 1 120 ? 7.357   -16.145 -50.734 1.00 54.66  ? 120 HIS B CD2 1 
ATOM   1993 C  CE1 . HIS B 1 120 ? 7.688   -18.297 -50.633 1.00 55.06  ? 120 HIS B CE1 1 
ATOM   1994 N  NE2 . HIS B 1 120 ? 7.012   -17.294 -50.068 1.00 54.24  ? 120 HIS B NE2 1 
ATOM   1995 N  N   . GLU B 1 121 ? 11.764  -15.651 -53.958 1.00 54.45  ? 121 GLU B N   1 
ATOM   1996 C  CA  . GLU B 1 121 ? 12.690  -15.580 -55.091 1.00 55.88  ? 121 GLU B CA  1 
ATOM   1997 C  C   . GLU B 1 121 ? 12.084  -14.887 -56.315 1.00 60.60  ? 121 GLU B C   1 
ATOM   1998 O  O   . GLU B 1 121 ? 12.717  -14.008 -56.898 1.00 60.73  ? 121 GLU B O   1 
ATOM   1999 C  CB  . GLU B 1 121 ? 13.163  -17.004 -55.442 1.00 58.37  ? 121 GLU B CB  1 
ATOM   2000 C  CG  . GLU B 1 121 ? 14.142  -17.114 -56.605 1.00 65.62  ? 121 GLU B CG  1 
ATOM   2001 C  CD  . GLU B 1 121 ? 14.274  -18.493 -57.229 1.00 86.15  ? 121 GLU B CD  1 
ATOM   2002 O  OE1 . GLU B 1 121 ? 15.204  -18.678 -58.047 1.00 97.09  ? 121 GLU B OE1 1 
ATOM   2003 O  OE2 . GLU B 1 121 ? 13.452  -19.387 -56.916 1.00 71.66  ? 121 GLU B OE2 1 
ATOM   2004 N  N   . LYS B 1 122 ? 10.855  -15.277 -56.687 1.00 58.33  ? 122 LYS B N   1 
ATOM   2005 C  CA  . LYS B 1 122 ? 10.164  -14.776 -57.868 1.00 59.89  ? 122 LYS B CA  1 
ATOM   2006 C  C   . LYS B 1 122 ? 8.851   -14.115 -57.525 1.00 62.88  ? 122 LYS B C   1 
ATOM   2007 O  O   . LYS B 1 122 ? 8.399   -14.145 -56.373 1.00 60.11  ? 122 LYS B O   1 
ATOM   2008 C  CB  . LYS B 1 122 ? 9.902   -15.928 -58.854 1.00 64.09  ? 122 LYS B CB  1 
ATOM   2009 C  CG  . LYS B 1 122 ? 11.151  -16.577 -59.431 1.00 77.87  ? 122 LYS B CG  1 
ATOM   2010 C  CD  . LYS B 1 122 ? 11.173  -18.064 -59.105 1.00 86.61  ? 122 LYS B CD  1 
ATOM   2011 C  CE  . LYS B 1 122 ? 10.836  -18.938 -60.287 1.00 89.41  ? 122 LYS B CE  1 
ATOM   2012 N  NZ  . LYS B 1 122 ? 12.029  -19.173 -61.141 1.00 101.92 ? 122 LYS B NZ  1 
ATOM   2013 N  N   . ALA B 1 123 ? 8.223   -13.538 -58.549 1.00 60.88  ? 123 ALA B N   1 
ATOM   2014 C  CA  . ALA B 1 123 ? 6.920   -12.911 -58.431 1.00 60.30  ? 123 ALA B CA  1 
ATOM   2015 C  C   . ALA B 1 123 ? 5.866   -13.970 -58.134 1.00 61.81  ? 123 ALA B C   1 
ATOM   2016 O  O   . ALA B 1 123 ? 5.952   -15.108 -58.595 1.00 60.94  ? 123 ALA B O   1 
ATOM   2017 C  CB  . ALA B 1 123 ? 6.571   -12.199 -59.730 1.00 62.87  ? 123 ALA B CB  1 
ATOM   2018 N  N   . ASP B 1 124 ? 4.893   -13.596 -57.329 1.00 58.13  ? 124 ASP B N   1 
ATOM   2019 C  CA  . ASP B 1 124 ? 3.739   -14.425 -57.036 1.00 57.36  ? 124 ASP B CA  1 
ATOM   2020 C  C   . ASP B 1 124 ? 2.794   -14.152 -58.226 1.00 61.06  ? 124 ASP B C   1 
ATOM   2021 O  O   . ASP B 1 124 ? 2.431   -12.996 -58.469 1.00 60.93  ? 124 ASP B O   1 
ATOM   2022 C  CB  . ASP B 1 124 ? 3.132   -14.000 -55.693 1.00 57.06  ? 124 ASP B CB  1 
ATOM   2023 C  CG  . ASP B 1 124 ? 1.739   -14.508 -55.356 1.00 64.38  ? 124 ASP B CG  1 
ATOM   2024 O  OD1 . ASP B 1 124 ? 1.176   -15.301 -56.150 1.00 67.41  ? 124 ASP B OD1 1 
ATOM   2025 O  OD2 . ASP B 1 124 ? 1.207   -14.102 -54.319 1.00 63.66  ? 124 ASP B OD2 1 
ATOM   2026 N  N   . ASP B 1 125 ? 2.420   -15.209 -58.972 1.00 58.71  ? 125 ASP B N   1 
ATOM   2027 C  CA  . ASP B 1 125 ? 1.551   -15.094 -60.162 1.00 60.43  ? 125 ASP B CA  1 
ATOM   2028 C  C   . ASP B 1 125 ? 0.063   -14.836 -59.824 1.00 65.78  ? 125 ASP B C   1 
ATOM   2029 O  O   . ASP B 1 125 ? -0.774  -14.740 -60.734 1.00 67.10  ? 125 ASP B O   1 
ATOM   2030 C  CB  . ASP B 1 125 ? 1.721   -16.306 -61.109 1.00 62.34  ? 125 ASP B CB  1 
ATOM   2031 C  CG  . ASP B 1 125 ? 1.360   -17.665 -60.534 1.00 62.19  ? 125 ASP B CG  1 
ATOM   2032 O  OD1 . ASP B 1 125 ? 0.421   -17.738 -59.721 1.00 59.41  ? 125 ASP B OD1 1 
ATOM   2033 O  OD2 . ASP B 1 125 ? 2.000   -18.658 -60.920 1.00 69.58  ? 125 ASP B OD2 1 
ATOM   2034 N  N   . LEU B 1 126 ? -0.255  -14.731 -58.514 1.00 62.03  ? 126 LEU B N   1 
ATOM   2035 C  CA  . LEU B 1 126 ? -1.561  -14.418 -57.923 1.00 62.21  ? 126 LEU B CA  1 
ATOM   2036 C  C   . LEU B 1 126 ? -2.661  -15.452 -58.266 1.00 67.66  ? 126 LEU B C   1 
ATOM   2037 O  O   . LEU B 1 126 ? -3.852  -15.134 -58.260 1.00 67.55  ? 126 LEU B O   1 
ATOM   2038 C  CB  . LEU B 1 126 ? -1.990  -12.967 -58.261 1.00 63.26  ? 126 LEU B CB  1 
ATOM   2039 C  CG  . LEU B 1 126 ? -0.920  -11.860 -58.088 1.00 67.66  ? 126 LEU B CG  1 
ATOM   2040 C  CD1 . LEU B 1 126 ? -1.380  -10.561 -58.719 1.00 69.88  ? 126 LEU B CD1 1 
ATOM   2041 C  CD2 . LEU B 1 126 ? -0.506  -11.664 -56.602 1.00 65.90  ? 126 LEU B CD2 1 
ATOM   2042 N  N   . GLY B 1 127 ? -2.230  -16.694 -58.481 1.00 64.72  ? 127 GLY B N   1 
ATOM   2043 C  CA  . GLY B 1 127 ? -3.081  -17.835 -58.798 1.00 65.18  ? 127 GLY B CA  1 
ATOM   2044 C  C   . GLY B 1 127 ? -3.499  -17.941 -60.247 1.00 69.82  ? 127 GLY B C   1 
ATOM   2045 O  O   . GLY B 1 127 ? -4.348  -18.772 -60.576 1.00 71.66  ? 127 GLY B O   1 
ATOM   2046 N  N   . LYS B 1 128 ? -2.889  -17.119 -61.132 1.00 65.04  ? 128 LYS B N   1 
ATOM   2047 C  CA  . LYS B 1 128 ? -3.206  -17.054 -62.568 1.00 66.06  ? 128 LYS B CA  1 
ATOM   2048 C  C   . LYS B 1 128 ? -1.985  -17.432 -63.438 1.00 67.04  ? 128 LYS B C   1 
ATOM   2049 O  O   . LYS B 1 128 ? -1.780  -16.856 -64.502 1.00 67.32  ? 128 LYS B O   1 
ATOM   2050 C  CB  . LYS B 1 128 ? -3.726  -15.643 -62.935 1.00 69.05  ? 128 LYS B CB  1 
ATOM   2051 C  CG  . LYS B 1 128 ? -4.884  -15.115 -62.076 1.00 80.51  ? 128 LYS B CG  1 
ATOM   2052 C  CD  . LYS B 1 128 ? -6.260  -15.397 -62.683 1.00 94.51  ? 128 LYS B CD  1 
ATOM   2053 C  CE  . LYS B 1 128 ? -7.329  -14.444 -62.183 1.00 104.03 ? 128 LYS B CE  1 
ATOM   2054 N  NZ  . LYS B 1 128 ? -7.658  -14.647 -60.744 1.00 105.42 ? 128 LYS B NZ  1 
ATOM   2055 N  N   . GLY B 1 129 ? -1.173  -18.373 -62.949 1.00 62.12  ? 129 GLY B N   1 
ATOM   2056 C  CA  . GLY B 1 129 ? 0.037   -18.850 -63.618 1.00 61.40  ? 129 GLY B CA  1 
ATOM   2057 C  C   . GLY B 1 129 ? -0.166  -20.032 -64.541 1.00 66.89  ? 129 GLY B C   1 
ATOM   2058 O  O   . GLY B 1 129 ? 0.767   -20.447 -65.221 1.00 66.01  ? 129 GLY B O   1 
ATOM   2059 N  N   . GLY B 1 130 ? -1.394  -20.541 -64.616 1.00 65.88  ? 130 GLY B N   1 
ATOM   2060 C  CA  . GLY B 1 130 ? -1.738  -21.627 -65.526 1.00 68.10  ? 130 GLY B CA  1 
ATOM   2061 C  C   . GLY B 1 130 ? -1.191  -23.013 -65.244 1.00 73.91  ? 130 GLY B C   1 
ATOM   2062 O  O   . GLY B 1 130 ? -0.987  -23.776 -66.189 1.00 76.12  ? 130 GLY B O   1 
ATOM   2063 N  N   . ASN B 1 131 ? -1.003  -23.380 -63.952 1.00 70.41  ? 131 ASN B N   1 
ATOM   2064 C  CA  . ASN B 1 131 ? -0.539  -24.717 -63.539 1.00 71.22  ? 131 ASN B CA  1 
ATOM   2065 C  C   . ASN B 1 131 ? -0.955  -25.061 -62.096 1.00 73.46  ? 131 ASN B C   1 
ATOM   2066 O  O   . ASN B 1 131 ? -1.415  -24.178 -61.373 1.00 70.23  ? 131 ASN B O   1 
ATOM   2067 C  CB  . ASN B 1 131 ? 0.982   -24.919 -63.774 1.00 71.55  ? 131 ASN B CB  1 
ATOM   2068 C  CG  . ASN B 1 131 ? 1.950   -24.040 -62.998 1.00 85.21  ? 131 ASN B CG  1 
ATOM   2069 O  OD1 . ASN B 1 131 ? 1.600   -23.303 -62.077 1.00 72.26  ? 131 ASN B OD1 1 
ATOM   2070 N  ND2 . ASN B 1 131 ? 3.221   -24.116 -63.359 1.00 79.36  ? 131 ASN B ND2 1 
ATOM   2071 N  N   . GLU B 1 132 ? -0.817  -26.345 -61.692 1.00 72.73  ? 132 GLU B N   1 
ATOM   2072 C  CA  . GLU B 1 132 ? -1.156  -26.829 -60.340 1.00 72.81  ? 132 GLU B CA  1 
ATOM   2073 C  C   . GLU B 1 132 ? -0.430  -26.070 -59.223 1.00 73.80  ? 132 GLU B C   1 
ATOM   2074 O  O   . GLU B 1 132 ? -1.039  -25.806 -58.185 1.00 72.96  ? 132 GLU B O   1 
ATOM   2075 C  CB  . GLU B 1 132 ? -0.917  -28.349 -60.225 1.00 76.66  ? 132 GLU B CB  1 
ATOM   2076 C  CG  . GLU B 1 132 ? -1.431  -28.995 -58.944 1.00 88.74  ? 132 GLU B CG  1 
ATOM   2077 C  CD  . GLU B 1 132 ? -1.624  -30.499 -59.010 1.00 118.03 ? 132 GLU B CD  1 
ATOM   2078 O  OE1 . GLU B 1 132 ? -2.760  -30.960 -58.754 1.00 114.76 ? 132 GLU B OE1 1 
ATOM   2079 O  OE2 . GLU B 1 132 ? -0.645  -31.218 -59.319 1.00 115.21 ? 132 GLU B OE2 1 
ATOM   2080 N  N   . GLU B 1 133 ? 0.850   -25.704 -59.433 1.00 69.02  ? 133 GLU B N   1 
ATOM   2081 C  CA  . GLU B 1 133 ? 1.661   -24.986 -58.437 1.00 66.53  ? 133 GLU B CA  1 
ATOM   2082 C  C   . GLU B 1 133 ? 1.151   -23.557 -58.180 1.00 68.74  ? 133 GLU B C   1 
ATOM   2083 O  O   . GLU B 1 133 ? 1.193   -23.090 -57.043 1.00 66.31  ? 133 GLU B O   1 
ATOM   2084 C  CB  . GLU B 1 133 ? 3.150   -24.992 -58.832 1.00 67.95  ? 133 GLU B CB  1 
ATOM   2085 C  CG  . GLU B 1 133 ? 4.110   -24.612 -57.711 1.00 76.47  ? 133 GLU B CG  1 
ATOM   2086 C  CD  . GLU B 1 133 ? 4.167   -25.574 -56.539 1.00 99.22  ? 133 GLU B CD  1 
ATOM   2087 O  OE1 . GLU B 1 133 ? 4.744   -26.674 -56.699 1.00 102.65 ? 133 GLU B OE1 1 
ATOM   2088 O  OE2 . GLU B 1 133 ? 3.640   -25.226 -55.458 1.00 87.24  ? 133 GLU B OE2 1 
ATOM   2089 N  N   . SER B 1 134 ? 0.643   -22.894 -59.235 1.00 66.51  ? 134 SER B N   1 
ATOM   2090 C  CA  . SER B 1 134 ? 0.078   -21.540 -59.201 1.00 65.17  ? 134 SER B CA  1 
ATOM   2091 C  C   . SER B 1 134 ? -1.119  -21.419 -58.220 1.00 69.72  ? 134 SER B C   1 
ATOM   2092 O  O   . SER B 1 134 ? -1.235  -20.412 -57.514 1.00 66.47  ? 134 SER B O   1 
ATOM   2093 C  CB  . SER B 1 134 ? -0.371  -21.132 -60.601 1.00 66.08  ? 134 SER B CB  1 
ATOM   2094 O  OG  . SER B 1 134 ? -1.004  -19.867 -60.581 1.00 67.21  ? 134 SER B OG  1 
ATOM   2095 N  N   . THR B 1 135 ? -1.986  -22.447 -58.182 1.00 69.50  ? 135 THR B N   1 
ATOM   2096 C  CA  . THR B 1 135 ? -3.165  -22.473 -57.307 1.00 70.37  ? 135 THR B CA  1 
ATOM   2097 C  C   . THR B 1 135 ? -2.801  -22.773 -55.836 1.00 74.84  ? 135 THR B C   1 
ATOM   2098 O  O   . THR B 1 135 ? -3.671  -22.665 -54.967 1.00 74.70  ? 135 THR B O   1 
ATOM   2099 C  CB  . THR B 1 135 ? -4.243  -23.417 -57.886 1.00 89.23  ? 135 THR B CB  1 
ATOM   2100 O  OG1 . THR B 1 135 ? -5.521  -23.006 -57.405 1.00 98.10  ? 135 THR B OG1 1 
ATOM   2101 C  CG2 . THR B 1 135 ? -4.006  -24.892 -57.558 1.00 87.71  ? 135 THR B CG2 1 
ATOM   2102 N  N   . LYS B 1 136 ? -1.530  -23.133 -55.556 1.00 70.98  ? 136 LYS B N   1 
ATOM   2103 C  CA  . LYS B 1 136 ? -1.063  -23.459 -54.200 1.00 69.65  ? 136 LYS B CA  1 
ATOM   2104 C  C   . LYS B 1 136 ? -0.099  -22.433 -53.608 1.00 72.14  ? 136 LYS B C   1 
ATOM   2105 O  O   . LYS B 1 136 ? -0.275  -22.028 -52.456 1.00 70.68  ? 136 LYS B O   1 
ATOM   2106 C  CB  . LYS B 1 136 ? -0.420  -24.860 -54.156 1.00 73.13  ? 136 LYS B CB  1 
ATOM   2107 C  CG  . LYS B 1 136 ? -1.360  -25.999 -54.548 1.00 86.77  ? 136 LYS B CG  1 
ATOM   2108 C  CD  . LYS B 1 136 ? -0.596  -27.299 -54.770 1.00 97.60  ? 136 LYS B CD  1 
ATOM   2109 C  CE  . LYS B 1 136 ? -1.500  -28.428 -55.200 1.00 107.79 ? 136 LYS B CE  1 
ATOM   2110 N  NZ  . LYS B 1 136 ? -0.742  -29.692 -55.402 1.00 116.49 ? 136 LYS B NZ  1 
ATOM   2111 N  N   . THR B 1 137 ? 0.944   -22.045 -54.367 1.00 69.21  ? 137 THR B N   1 
ATOM   2112 C  CA  . THR B 1 137 ? 2.000   -21.137 -53.885 1.00 67.43  ? 137 THR B CA  1 
ATOM   2113 C  C   . THR B 1 137 ? 2.224   -19.898 -54.761 1.00 69.04  ? 137 THR B C   1 
ATOM   2114 O  O   . THR B 1 137 ? 2.978   -18.994 -54.375 1.00 66.44  ? 137 THR B O   1 
ATOM   2115 C  CB  . THR B 1 137 ? 3.323   -21.916 -53.711 1.00 78.31  ? 137 THR B CB  1 
ATOM   2116 O  OG1 . THR B 1 137 ? 3.676   -22.529 -54.958 1.00 81.26  ? 137 THR B OG1 1 
ATOM   2117 C  CG2 . THR B 1 137 ? 3.254   -22.961 -52.599 1.00 76.31  ? 137 THR B CG2 1 
ATOM   2118 N  N   . GLY B 1 138 ? 1.600   -19.888 -55.937 1.00 65.27  ? 138 GLY B N   1 
ATOM   2119 C  CA  . GLY B 1 138 ? 1.716   -18.793 -56.888 1.00 64.28  ? 138 GLY B CA  1 
ATOM   2120 C  C   . GLY B 1 138 ? 3.030   -18.744 -57.637 1.00 65.80  ? 138 GLY B C   1 
ATOM   2121 O  O   . GLY B 1 138 ? 3.385   -17.688 -58.169 1.00 64.13  ? 138 GLY B O   1 
ATOM   2122 N  N   . ASN B 1 139 ? 3.755   -19.892 -57.697 1.00 62.95  ? 139 ASN B N   1 
ATOM   2123 C  CA  . ASN B 1 139 ? 5.061   -20.061 -58.369 1.00 63.14  ? 139 ASN B CA  1 
ATOM   2124 C  C   . ASN B 1 139 ? 6.088   -19.007 -57.931 1.00 64.62  ? 139 ASN B C   1 
ATOM   2125 O  O   . ASN B 1 139 ? 6.878   -18.535 -58.748 1.00 65.77  ? 139 ASN B O   1 
ATOM   2126 C  CB  . ASN B 1 139 ? 4.907   -20.072 -59.901 1.00 66.75  ? 139 ASN B CB  1 
ATOM   2127 C  CG  . ASN B 1 139 ? 4.389   -21.358 -60.479 1.00 90.59  ? 139 ASN B CG  1 
ATOM   2128 O  OD1 . ASN B 1 139 ? 4.930   -22.444 -60.241 1.00 82.59  ? 139 ASN B OD1 1 
ATOM   2129 N  ND2 . ASN B 1 139 ? 3.337   -21.256 -61.280 1.00 83.89  ? 139 ASN B ND2 1 
ATOM   2130 N  N   . ALA B 1 140 ? 6.068   -18.631 -56.644 1.00 57.88  ? 140 ALA B N   1 
ATOM   2131 C  CA  . ALA B 1 140 ? 6.958   -17.604 -56.117 1.00 56.63  ? 140 ALA B CA  1 
ATOM   2132 C  C   . ALA B 1 140 ? 8.406   -18.084 -55.878 1.00 61.07  ? 140 ALA B C   1 
ATOM   2133 O  O   . ALA B 1 140 ? 9.293   -17.266 -55.628 1.00 60.44  ? 140 ALA B O   1 
ATOM   2134 C  CB  . ALA B 1 140 ? 6.360   -16.989 -54.867 1.00 55.21  ? 140 ALA B CB  1 
ATOM   2135 N  N   . GLY B 1 141 ? 8.636   -19.389 -56.010 1.00 59.00  ? 141 GLY B N   1 
ATOM   2136 C  CA  . GLY B 1 141 ? 9.960   -19.994 -55.888 1.00 59.24  ? 141 GLY B CA  1 
ATOM   2137 C  C   . GLY B 1 141 ? 10.490  -20.109 -54.475 1.00 60.41  ? 141 GLY B C   1 
ATOM   2138 O  O   . GLY B 1 141 ? 9.720   -20.274 -53.521 1.00 59.01  ? 141 GLY B O   1 
ATOM   2139 N  N   . SER B 1 142 ? 11.824  -20.023 -54.344 1.00 55.63  ? 142 SER B N   1 
ATOM   2140 C  CA  . SER B 1 142 ? 12.551  -20.138 -53.086 1.00 54.05  ? 142 SER B CA  1 
ATOM   2141 C  C   . SER B 1 142 ? 12.232  -19.058 -52.065 1.00 56.01  ? 142 SER B C   1 
ATOM   2142 O  O   . SER B 1 142 ? 11.739  -17.987 -52.401 1.00 54.34  ? 142 SER B O   1 
ATOM   2143 C  CB  . SER B 1 142 ? 14.054  -20.183 -53.341 1.00 57.50  ? 142 SER B CB  1 
ATOM   2144 O  OG  . SER B 1 142 ? 14.363  -21.371 -54.047 1.00 74.89  ? 142 SER B OG  1 
ATOM   2145 N  N   . ARG B 1 143 ? 12.567  -19.340 -50.812 1.00 53.41  ? 143 ARG B N   1 
ATOM   2146 C  CA  . ARG B 1 143 ? 12.373  -18.429 -49.699 1.00 51.00  ? 143 ARG B CA  1 
ATOM   2147 C  C   . ARG B 1 143 ? 13.680  -17.680 -49.498 1.00 55.13  ? 143 ARG B C   1 
ATOM   2148 O  O   . ARG B 1 143 ? 14.669  -18.270 -49.056 1.00 56.41  ? 143 ARG B O   1 
ATOM   2149 C  CB  . ARG B 1 143 ? 11.939  -19.227 -48.459 1.00 50.41  ? 143 ARG B CB  1 
ATOM   2150 C  CG  . ARG B 1 143 ? 10.663  -20.009 -48.752 1.00 55.57  ? 143 ARG B CG  1 
ATOM   2151 C  CD  . ARG B 1 143 ? 10.158  -20.869 -47.625 1.00 56.67  ? 143 ARG B CD  1 
ATOM   2152 N  NE  . ARG B 1 143 ? 9.055   -21.685 -48.127 1.00 57.80  ? 143 ARG B NE  1 
ATOM   2153 C  CZ  . ARG B 1 143 ? 8.222   -22.395 -47.377 1.00 67.00  ? 143 ARG B CZ  1 
ATOM   2154 N  NH1 . ARG B 1 143 ? 8.338   -22.388 -46.055 1.00 54.64  ? 143 ARG B NH1 1 
ATOM   2155 N  NH2 . ARG B 1 143 ? 7.255   -23.106 -47.943 1.00 51.85  ? 143 ARG B NH2 1 
ATOM   2156 N  N   . LEU B 1 144 ? 13.715  -16.399 -49.905 1.00 50.26  ? 144 LEU B N   1 
ATOM   2157 C  CA  . LEU B 1 144 ? 14.934  -15.584 -49.803 1.00 49.95  ? 144 LEU B CA  1 
ATOM   2158 C  C   . LEU B 1 144 ? 15.271  -15.205 -48.370 1.00 51.87  ? 144 LEU B C   1 
ATOM   2159 O  O   . LEU B 1 144 ? 16.419  -15.323 -47.956 1.00 51.23  ? 144 LEU B O   1 
ATOM   2160 C  CB  . LEU B 1 144 ? 14.838  -14.322 -50.669 1.00 50.57  ? 144 LEU B CB  1 
ATOM   2161 C  CG  . LEU B 1 144 ? 14.681  -14.519 -52.177 1.00 56.45  ? 144 LEU B CG  1 
ATOM   2162 C  CD1 . LEU B 1 144 ? 14.592  -13.183 -52.878 1.00 57.28  ? 144 LEU B CD1 1 
ATOM   2163 C  CD2 . LEU B 1 144 ? 15.817  -15.353 -52.774 1.00 60.65  ? 144 LEU B CD2 1 
ATOM   2164 N  N   . ALA B 1 145 ? 14.278  -14.713 -47.626 1.00 47.78  ? 145 ALA B N   1 
ATOM   2165 C  CA  . ALA B 1 145 ? 14.459  -14.326 -46.227 1.00 46.37  ? 145 ALA B CA  1 
ATOM   2166 C  C   . ALA B 1 145 ? 13.132  -14.462 -45.510 1.00 50.48  ? 145 ALA B C   1 
ATOM   2167 O  O   . ALA B 1 145 ? 12.067  -14.412 -46.134 1.00 48.39  ? 145 ALA B O   1 
ATOM   2168 C  CB  . ALA B 1 145 ? 14.987  -12.899 -46.118 1.00 46.62  ? 145 ALA B CB  1 
ATOM   2169 N  N   . CYS B 1 146 ? 13.201  -14.675 -44.197 1.00 49.29  ? 146 CYS B N   1 
ATOM   2170 C  CA  . CYS B 1 146 ? 12.023  -14.850 -43.344 1.00 48.94  ? 146 CYS B CA  1 
ATOM   2171 C  C   . CYS B 1 146 ? 12.314  -14.398 -41.929 1.00 48.06  ? 146 CYS B C   1 
ATOM   2172 O  O   . CYS B 1 146 ? 13.478  -14.189 -41.563 1.00 45.38  ? 146 CYS B O   1 
ATOM   2173 C  CB  . CYS B 1 146 ? 11.542  -16.299 -43.376 1.00 51.32  ? 146 CYS B CB  1 
ATOM   2174 S  SG  . CYS B 1 146 ? 12.761  -17.491 -42.758 1.00 57.31  ? 146 CYS B SG  1 
ATOM   2175 N  N   . GLY B 1 147 ? 11.251  -14.277 -41.141 1.00 42.93  ? 147 GLY B N   1 
ATOM   2176 C  CA  . GLY B 1 147 ? 11.326  -13.894 -39.738 1.00 42.95  ? 147 GLY B CA  1 
ATOM   2177 C  C   . GLY B 1 147 ? 10.017  -14.142 -39.033 1.00 44.87  ? 147 GLY B C   1 
ATOM   2178 O  O   . GLY B 1 147 ? 8.947   -14.101 -39.657 1.00 44.12  ? 147 GLY B O   1 
ATOM   2179 N  N   . VAL B 1 148 ? 10.086  -14.395 -37.726 1.00 41.49  ? 148 VAL B N   1 
ATOM   2180 C  CA  . VAL B 1 148 ? 8.875   -14.624 -36.939 1.00 41.54  ? 148 VAL B CA  1 
ATOM   2181 C  C   . VAL B 1 148 ? 8.264   -13.255 -36.608 1.00 45.35  ? 148 VAL B C   1 
ATOM   2182 O  O   . VAL B 1 148 ? 8.987   -12.358 -36.175 1.00 46.49  ? 148 VAL B O   1 
ATOM   2183 C  CB  . VAL B 1 148 ? 9.150   -15.480 -35.670 1.00 45.70  ? 148 VAL B CB  1 
ATOM   2184 C  CG1 . VAL B 1 148 ? 7.846   -15.806 -34.933 1.00 45.51  ? 148 VAL B CG1 1 
ATOM   2185 C  CG2 . VAL B 1 148 ? 9.895   -16.768 -36.031 1.00 46.08  ? 148 VAL B CG2 1 
ATOM   2186 N  N   . ILE B 1 149 ? 6.943   -13.109 -36.794 1.00 40.69  ? 149 ILE B N   1 
ATOM   2187 C  CA  . ILE B 1 149 ? 6.223   -11.871 -36.496 1.00 39.94  ? 149 ILE B CA  1 
ATOM   2188 C  C   . ILE B 1 149 ? 6.035   -11.790 -34.986 1.00 43.82  ? 149 ILE B C   1 
ATOM   2189 O  O   . ILE B 1 149 ? 5.361   -12.634 -34.390 1.00 43.19  ? 149 ILE B O   1 
ATOM   2190 C  CB  . ILE B 1 149 ? 4.883   -11.783 -37.285 1.00 42.39  ? 149 ILE B CB  1 
ATOM   2191 C  CG1 . ILE B 1 149 ? 5.139   -11.837 -38.822 1.00 42.68  ? 149 ILE B CG1 1 
ATOM   2192 C  CG2 . ILE B 1 149 ? 4.071   -10.535 -36.884 1.00 40.59  ? 149 ILE B CG2 1 
ATOM   2193 C  CD1 . ILE B 1 149 ? 3.939   -12.391 -39.648 1.00 44.08  ? 149 ILE B CD1 1 
ATOM   2194 N  N   . GLY B 1 150 ? 6.649   -10.784 -34.380 1.00 41.86  ? 150 GLY B N   1 
ATOM   2195 C  CA  . GLY B 1 150 ? 6.603   -10.608 -32.937 1.00 41.93  ? 150 GLY B CA  1 
ATOM   2196 C  C   . GLY B 1 150 ? 5.926   -9.340  -32.478 1.00 47.20  ? 150 GLY B C   1 
ATOM   2197 O  O   . GLY B 1 150 ? 5.829   -8.378  -33.232 1.00 47.62  ? 150 GLY B O   1 
ATOM   2198 N  N   . ILE B 1 151 ? 5.470   -9.335  -31.222 1.00 44.60  ? 151 ILE B N   1 
ATOM   2199 C  CA  . ILE B 1 151 ? 4.810   -8.196  -30.575 1.00 45.50  ? 151 ILE B CA  1 
ATOM   2200 C  C   . ILE B 1 151 ? 5.788   -7.012  -30.463 1.00 49.73  ? 151 ILE B C   1 
ATOM   2201 O  O   . ILE B 1 151 ? 6.904   -7.171  -29.951 1.00 48.01  ? 151 ILE B O   1 
ATOM   2202 C  CB  . ILE B 1 151 ? 4.228   -8.627  -29.190 1.00 49.32  ? 151 ILE B CB  1 
ATOM   2203 C  CG1 . ILE B 1 151 ? 3.138   -9.720  -29.372 1.00 50.07  ? 151 ILE B CG1 1 
ATOM   2204 C  CG2 . ILE B 1 151 ? 3.682   -7.419  -28.402 1.00 50.80  ? 151 ILE B CG2 1 
ATOM   2205 C  CD1 . ILE B 1 151 ? 2.866   -10.597 -28.090 1.00 55.07  ? 151 ILE B CD1 1 
ATOM   2206 N  N   . ALA B 1 152 ? 5.365   -5.833  -30.947 1.00 47.79  ? 152 ALA B N   1 
ATOM   2207 C  CA  . ALA B 1 152 ? 6.189   -4.625  -30.895 1.00 49.00  ? 152 ALA B CA  1 
ATOM   2208 C  C   . ALA B 1 152 ? 5.618   -3.610  -29.904 1.00 55.22  ? 152 ALA B C   1 
ATOM   2209 O  O   . ALA B 1 152 ? 4.450   -3.717  -29.517 1.00 55.66  ? 152 ALA B O   1 
ATOM   2210 C  CB  . ALA B 1 152 ? 6.313   -4.010  -32.281 1.00 49.79  ? 152 ALA B CB  1 
ATOM   2211 N  N   . GLN B 1 153 ? 6.450   -2.645  -29.476 1.00 52.59  ? 153 GLN B N   1 
ATOM   2212 C  CA  . GLN B 1 153 ? 6.057   -1.586  -28.552 1.00 56.70  ? 153 GLN B CA  1 
ATOM   2213 C  C   . GLN B 1 153 ? 5.294   -0.486  -29.314 1.00 75.61  ? 153 GLN B C   1 
ATOM   2214 O  O   . GLN B 1 153 ? 5.747   -0.090  -30.415 1.00 75.41  ? 153 GLN B O   1 
ATOM   2215 C  CB  . GLN B 1 153 ? 7.295   -1.007  -27.859 1.00 58.78  ? 153 GLN B CB  1 
ATOM   2216 C  CG  . GLN B 1 153 ? 6.982   -0.080  -26.685 1.00 77.52  ? 153 GLN B CG  1 
ATOM   2217 C  CD  . GLN B 1 153 ? 8.217   0.230   -25.877 1.00 95.59  ? 153 GLN B CD  1 
ATOM   2218 O  OE1 . GLN B 1 153 ? 9.259   0.641   -26.405 1.00 89.49  ? 153 GLN B OE1 1 
ATOM   2219 N  NE2 . GLN B 1 153 ? 8.123   0.037   -24.573 1.00 90.18  ? 153 GLN B NE2 1 
ATOM   2220 O  OXT . GLN B 1 153 ? 4.249   -0.023  -28.802 1.00 97.97  ? 153 GLN B OXT 1 
ATOM   2221 N  N   . ALA C 1 1   ? -10.602 5.491   -14.064 1.00 86.01  ? 1   ALA D N   1 
ATOM   2222 C  CA  . ALA C 1 1   ? -10.840 4.133   -13.576 1.00 81.93  ? 1   ALA D CA  1 
ATOM   2223 C  C   . ALA C 1 1   ? -12.056 3.483   -14.254 1.00 80.91  ? 1   ALA D C   1 
ATOM   2224 O  O   . ALA C 1 1   ? -13.075 4.149   -14.462 1.00 80.59  ? 1   ALA D O   1 
ATOM   2225 C  CB  . ALA C 1 1   ? -11.019 4.142   -12.064 1.00 82.45  ? 1   ALA D CB  1 
ATOM   2226 N  N   . THR C 1 2   ? -11.941 2.181   -14.596 1.00 73.16  ? 2   THR D N   1 
ATOM   2227 C  CA  . THR C 1 2   ? -13.016 1.417   -15.241 1.00 68.84  ? 2   THR D CA  1 
ATOM   2228 C  C   . THR C 1 2   ? -14.131 1.104   -14.224 1.00 67.26  ? 2   THR D C   1 
ATOM   2229 O  O   . THR C 1 2   ? -13.863 0.743   -13.072 1.00 65.95  ? 2   THR D O   1 
ATOM   2230 C  CB  . THR C 1 2   ? -12.470 0.190   -16.019 1.00 77.22  ? 2   THR D CB  1 
ATOM   2231 O  OG1 . THR C 1 2   ? -13.548 -0.512  -16.631 1.00 73.67  ? 2   THR D OG1 1 
ATOM   2232 C  CG2 . THR C 1 2   ? -11.637 -0.767  -15.159 1.00 78.01  ? 2   THR D CG2 1 
ATOM   2233 N  N   . LYS C 1 3   ? -15.385 1.309   -14.659 1.00 60.47  ? 3   LYS D N   1 
ATOM   2234 C  CA  . LYS C 1 3   ? -16.586 1.122   -13.851 1.00 57.47  ? 3   LYS D CA  1 
ATOM   2235 C  C   . LYS C 1 3   ? -17.621 0.246   -14.550 1.00 56.71  ? 3   LYS D C   1 
ATOM   2236 O  O   . LYS C 1 3   ? -17.755 0.286   -15.776 1.00 55.68  ? 3   LYS D O   1 
ATOM   2237 C  CB  . LYS C 1 3   ? -17.220 2.481   -13.514 1.00 61.78  ? 3   LYS D CB  1 
ATOM   2238 C  CG  . LYS C 1 3   ? -16.532 3.235   -12.379 1.00 77.37  ? 3   LYS D CG  1 
ATOM   2239 C  CD  . LYS C 1 3   ? -17.114 4.640   -12.186 1.00 91.20  ? 3   LYS D CD  1 
ATOM   2240 C  CE  . LYS C 1 3   ? -18.364 4.671   -11.330 1.00 101.19 ? 3   LYS D CE  1 
ATOM   2241 N  NZ  . LYS C 1 3   ? -18.995 6.017   -11.319 1.00 110.61 ? 3   LYS D NZ  1 
ATOM   2242 N  N   . ALA C 1 4   ? -18.355 -0.539  -13.751 1.00 50.24  ? 4   ALA D N   1 
ATOM   2243 C  CA  . ALA C 1 4   ? -19.438 -1.401  -14.214 1.00 47.30  ? 4   ALA D CA  1 
ATOM   2244 C  C   . ALA C 1 4   ? -20.614 -1.284  -13.248 1.00 49.91  ? 4   ALA D C   1 
ATOM   2245 O  O   . ALA C 1 4   ? -20.430 -0.920  -12.087 1.00 50.46  ? 4   ALA D O   1 
ATOM   2246 C  CB  . ALA C 1 4   ? -18.974 -2.843  -14.326 1.00 46.28  ? 4   ALA D CB  1 
ATOM   2247 N  N   . VAL C 1 5   ? -21.820 -1.555  -13.742 1.00 45.29  ? 5   VAL D N   1 
ATOM   2248 C  CA  . VAL C 1 5   ? -23.062 -1.476  -12.977 1.00 45.02  ? 5   VAL D CA  1 
ATOM   2249 C  C   . VAL C 1 5   ? -23.984 -2.658  -13.331 1.00 48.78  ? 5   VAL D C   1 
ATOM   2250 O  O   . VAL C 1 5   ? -23.928 -3.185  -14.447 1.00 47.44  ? 5   VAL D O   1 
ATOM   2251 C  CB  . VAL C 1 5   ? -23.741 -0.082  -13.152 1.00 49.76  ? 5   VAL D CB  1 
ATOM   2252 C  CG1 . VAL C 1 5   ? -24.364 0.081   -14.544 1.00 49.20  ? 5   VAL D CG1 1 
ATOM   2253 C  CG2 . VAL C 1 5   ? -24.763 0.200   -12.047 1.00 50.21  ? 5   VAL D CG2 1 
ATOM   2254 N  N   . CYS C 1 6   ? -24.831 -3.061  -12.373 1.00 46.73  ? 6   CYS D N   1 
ATOM   2255 C  CA  . CYS C 1 6   ? -25.777 -4.154  -12.548 1.00 46.35  ? 6   CYS D CA  1 
ATOM   2256 C  C   . CYS C 1 6   ? -27.099 -3.849  -11.860 1.00 49.80  ? 6   CYS D C   1 
ATOM   2257 O  O   . CYS C 1 6   ? -27.116 -3.493  -10.676 1.00 49.14  ? 6   CYS D O   1 
ATOM   2258 C  CB  . CYS C 1 6   ? -25.176 -5.465  -12.049 1.00 46.38  ? 6   CYS D CB  1 
ATOM   2259 S  SG  . CYS C 1 6   ? -26.235 -6.906  -12.333 1.00 50.26  ? 6   CYS D SG  1 
ATOM   2260 N  N   . VAL C 1 7   ? -28.207 -4.000  -12.604 1.00 45.76  ? 7   VAL D N   1 
ATOM   2261 C  CA  . VAL C 1 7   ? -29.564 -3.814  -12.090 1.00 46.65  ? 7   VAL D CA  1 
ATOM   2262 C  C   . VAL C 1 7   ? -30.124 -5.216  -11.915 1.00 49.63  ? 7   VAL D C   1 
ATOM   2263 O  O   . VAL C 1 7   ? -30.253 -5.956  -12.885 1.00 48.99  ? 7   VAL D O   1 
ATOM   2264 C  CB  . VAL C 1 7   ? -30.468 -2.917  -12.985 1.00 52.09  ? 7   VAL D CB  1 
ATOM   2265 C  CG1 . VAL C 1 7   ? -31.827 -2.660  -12.314 1.00 53.87  ? 7   VAL D CG1 1 
ATOM   2266 C  CG2 . VAL C 1 7   ? -29.779 -1.598  -13.308 1.00 52.47  ? 7   VAL D CG2 1 
ATOM   2267 N  N   . LEU C 1 8   ? -30.406 -5.590  -10.675 1.00 47.21  ? 8   LEU D N   1 
ATOM   2268 C  CA  . LEU C 1 8   ? -30.901 -6.920  -10.331 1.00 48.00  ? 8   LEU D CA  1 
ATOM   2269 C  C   . LEU C 1 8   ? -32.413 -6.919  -10.298 1.00 54.10  ? 8   LEU D C   1 
ATOM   2270 O  O   . LEU C 1 8   ? -33.018 -6.121  -9.580  1.00 54.11  ? 8   LEU D O   1 
ATOM   2271 C  CB  . LEU C 1 8   ? -30.361 -7.383  -8.952  1.00 48.24  ? 8   LEU D CB  1 
ATOM   2272 C  CG  . LEU C 1 8   ? -28.840 -7.641  -8.759  1.00 52.00  ? 8   LEU D CG  1 
ATOM   2273 C  CD1 . LEU C 1 8   ? -28.372 -8.902  -9.424  1.00 50.32  ? 8   LEU D CD1 1 
ATOM   2274 C  CD2 . LEU C 1 8   ? -27.979 -6.437  -9.085  1.00 55.61  ? 8   LEU D CD2 1 
ATOM   2275 N  N   . LYS C 1 9   ? -33.018 -7.834  -11.060 1.00 53.04  ? 9   LYS D N   1 
ATOM   2276 C  CA  . LYS C 1 9   ? -34.469 -8.013  -11.130 1.00 56.14  ? 9   LYS D CA  1 
ATOM   2277 C  C   . LYS C 1 9   ? -34.800 -9.498  -11.278 1.00 61.80  ? 9   LYS D C   1 
ATOM   2278 O  O   . LYS C 1 9   ? -33.965 -10.285 -11.732 1.00 59.06  ? 9   LYS D O   1 
ATOM   2279 C  CB  . LYS C 1 9   ? -35.075 -7.191  -12.280 1.00 59.05  ? 9   LYS D CB  1 
ATOM   2280 C  CG  . LYS C 1 9   ? -35.264 -5.711  -11.956 1.00 71.80  ? 9   LYS D CG  1 
ATOM   2281 C  CD  . LYS C 1 9   ? -35.904 -4.953  -13.125 1.00 82.96  ? 9   LYS D CD  1 
ATOM   2282 C  CE  . LYS C 1 9   ? -35.481 -3.502  -13.216 1.00 91.67  ? 9   LYS D CE  1 
ATOM   2283 N  NZ  . LYS C 1 9   ? -35.949 -2.693  -12.057 1.00 101.49 ? 9   LYS D NZ  1 
ATOM   2284 N  N   . GLY C 1 10  ? -35.999 -9.862  -10.852 1.00 62.36  ? 10  GLY D N   1 
ATOM   2285 C  CA  . GLY C 1 10  ? -36.496 -11.230 -10.910 1.00 64.05  ? 10  GLY D CA  1 
ATOM   2286 C  C   . GLY C 1 10  ? -38.006 -11.315 -10.958 1.00 71.63  ? 10  GLY D C   1 
ATOM   2287 O  O   . GLY C 1 10  ? -38.689 -10.301 -11.146 1.00 72.11  ? 10  GLY D O   1 
ATOM   2288 N  N   . ASP C 1 11  ? -38.529 -12.539 -10.790 1.00 70.63  ? 11  ASP D N   1 
ATOM   2289 C  CA  . ASP C 1 11  ? -39.960 -12.840 -10.815 1.00 74.27  ? 11  ASP D CA  1 
ATOM   2290 C  C   . ASP C 1 11  ? -40.696 -12.395 -9.541  1.00 79.49  ? 11  ASP D C   1 
ATOM   2291 O  O   . ASP C 1 11  ? -41.906 -12.179 -9.580  1.00 82.36  ? 11  ASP D O   1 
ATOM   2292 C  CB  . ASP C 1 11  ? -40.189 -14.330 -11.118 1.00 78.25  ? 11  ASP D CB  1 
ATOM   2293 C  CG  . ASP C 1 11  ? -39.742 -14.733 -12.514 1.00 90.26  ? 11  ASP D CG  1 
ATOM   2294 O  OD1 . ASP C 1 11  ? -40.358 -14.261 -13.495 1.00 92.25  ? 11  ASP D OD1 1 
ATOM   2295 O  OD2 . ASP C 1 11  ? -38.777 -15.522 -12.626 1.00 94.97  ? 11  ASP D OD2 1 
ATOM   2296 N  N   . GLY C 1 12  ? -39.951 -12.236 -8.450  1.00 74.09  ? 12  GLY D N   1 
ATOM   2297 C  CA  . GLY C 1 12  ? -40.467 -11.803 -7.157  1.00 76.05  ? 12  GLY D CA  1 
ATOM   2298 C  C   . GLY C 1 12  ? -40.154 -10.354 -6.825  1.00 77.59  ? 12  GLY D C   1 
ATOM   2299 O  O   . GLY C 1 12  ? -39.946 -9.544  -7.733  1.00 74.70  ? 12  GLY D O   1 
ATOM   2300 N  N   . PRO C 1 13  ? -40.117 -9.979  -5.526  1.00 75.65  ? 13  PRO D N   1 
ATOM   2301 C  CA  . PRO C 1 13  ? -39.862 -8.572  -5.180  1.00 75.22  ? 13  PRO D CA  1 
ATOM   2302 C  C   . PRO C 1 13  ? -38.382 -8.215  -4.984  1.00 75.52  ? 13  PRO D C   1 
ATOM   2303 O  O   . PRO C 1 13  ? -38.079 -7.096  -4.554  1.00 75.76  ? 13  PRO D O   1 
ATOM   2304 C  CB  . PRO C 1 13  ? -40.659 -8.401  -3.884  1.00 80.93  ? 13  PRO D CB  1 
ATOM   2305 C  CG  . PRO C 1 13  ? -40.591 -9.753  -3.231  1.00 86.16  ? 13  PRO D CG  1 
ATOM   2306 C  CD  . PRO C 1 13  ? -40.362 -10.788 -4.311  1.00 79.69  ? 13  PRO D CD  1 
ATOM   2307 N  N   . VAL C 1 14  ? -37.465 -9.162  -5.270  1.00 68.43  ? 14  VAL D N   1 
ATOM   2308 C  CA  . VAL C 1 14  ? -36.023 -8.942  -5.104  1.00 64.27  ? 14  VAL D CA  1 
ATOM   2309 C  C   . VAL C 1 14  ? -35.499 -8.015  -6.201  1.00 65.59  ? 14  VAL D C   1 
ATOM   2310 O  O   . VAL C 1 14  ? -35.544 -8.359  -7.387  1.00 63.45  ? 14  VAL D O   1 
ATOM   2311 C  CB  . VAL C 1 14  ? -35.195 -10.250 -4.977  1.00 65.87  ? 14  VAL D CB  1 
ATOM   2312 C  CG1 . VAL C 1 14  ? -33.726 -9.941  -4.679  1.00 62.63  ? 14  VAL D CG1 1 
ATOM   2313 C  CG2 . VAL C 1 14  ? -35.775 -11.176 -3.911  1.00 68.66  ? 14  VAL D CG2 1 
ATOM   2314 N  N   . GLN C 1 15  ? -35.045 -6.816  -5.800  1.00 62.25  ? 15  GLN D N   1 
ATOM   2315 C  CA  . GLN C 1 15  ? -34.509 -5.827  -6.736  1.00 60.49  ? 15  GLN D CA  1 
ATOM   2316 C  C   . GLN C 1 15  ? -33.378 -5.008  -6.130  1.00 62.76  ? 15  GLN D C   1 
ATOM   2317 O  O   . GLN C 1 15  ? -33.374 -4.755  -4.931  1.00 63.81  ? 15  GLN D O   1 
ATOM   2318 C  CB  . GLN C 1 15  ? -35.610 -4.929  -7.342  1.00 63.60  ? 15  GLN D CB  1 
ATOM   2319 C  CG  . GLN C 1 15  ? -36.405 -4.102  -6.330  1.00 85.96  ? 15  GLN D CG  1 
ATOM   2320 C  CD  . GLN C 1 15  ? -37.520 -3.332  -6.989  1.00 107.67 ? 15  GLN D CD  1 
ATOM   2321 O  OE1 . GLN C 1 15  ? -37.293 -2.390  -7.759  1.00 102.17 ? 15  GLN D OE1 1 
ATOM   2322 N  NE2 . GLN C 1 15  ? -38.753 -3.715  -6.696  1.00 104.30 ? 15  GLN D NE2 1 
ATOM   2323 N  N   . GLY C 1 16  ? -32.427 -4.602  -6.963  1.00 57.30  ? 16  GLY D N   1 
ATOM   2324 C  CA  . GLY C 1 16  ? -31.305 -3.811  -6.481  1.00 56.98  ? 16  GLY D CA  1 
ATOM   2325 C  C   . GLY C 1 16  ? -30.373 -3.275  -7.540  1.00 58.26  ? 16  GLY D C   1 
ATOM   2326 O  O   . GLY C 1 16  ? -30.568 -3.523  -8.733  1.00 57.15  ? 16  GLY D O   1 
ATOM   2327 N  N   . ILE C 1 17  ? -29.364 -2.505  -7.089  1.00 53.32  ? 17  ILE D N   1 
ATOM   2328 C  CA  . ILE C 1 17  ? -28.330 -1.898  -7.927  1.00 52.28  ? 17  ILE D CA  1 
ATOM   2329 C  C   . ILE C 1 17  ? -26.969 -2.188  -7.322  1.00 54.80  ? 17  ILE D C   1 
ATOM   2330 O  O   . ILE C 1 17  ? -26.728 -1.857  -6.159  1.00 56.42  ? 17  ILE D O   1 
ATOM   2331 C  CB  . ILE C 1 17  ? -28.560 -0.374  -8.184  1.00 57.37  ? 17  ILE D CB  1 
ATOM   2332 C  CG1 . ILE C 1 17  ? -29.818 -0.144  -9.058  1.00 58.49  ? 17  ILE D CG1 1 
ATOM   2333 C  CG2 . ILE C 1 17  ? -27.314 0.272   -8.844  1.00 56.97  ? 17  ILE D CG2 1 
ATOM   2334 C  CD1 . ILE C 1 17  ? -30.559 1.161   -8.803  1.00 69.16  ? 17  ILE D CD1 1 
ATOM   2335 N  N   . ILE C 1 18  ? -26.076 -2.801  -8.116  1.00 49.65  ? 18  ILE D N   1 
ATOM   2336 C  CA  . ILE C 1 18  ? -24.714 -3.131  -7.702  1.00 48.07  ? 18  ILE D CA  1 
ATOM   2337 C  C   . ILE C 1 18  ? -23.708 -2.447  -8.632  1.00 52.82  ? 18  ILE D C   1 
ATOM   2338 O  O   . ILE C 1 18  ? -23.826 -2.547  -9.846  1.00 50.49  ? 18  ILE D O   1 
ATOM   2339 C  CB  . ILE C 1 18  ? -24.495 -4.671  -7.577  1.00 48.97  ? 18  ILE D CB  1 
ATOM   2340 C  CG1 . ILE C 1 18  ? -25.435 -5.323  -6.504  1.00 49.81  ? 18  ILE D CG1 1 
ATOM   2341 C  CG2 . ILE C 1 18  ? -23.011 -5.033  -7.346  1.00 48.15  ? 18  ILE D CG2 1 
ATOM   2342 C  CD1 . ILE C 1 18  ? -25.333 -4.781  -4.961  1.00 50.74  ? 18  ILE D CD1 1 
ATOM   2343 N  N   . ASN C 1 19  ? -22.732 -1.744  -8.038  1.00 51.52  ? 19  ASN D N   1 
ATOM   2344 C  CA  . ASN C 1 19  ? -21.662 -1.020  -8.719  1.00 51.32  ? 19  ASN D CA  1 
ATOM   2345 C  C   . ASN C 1 19  ? -20.361 -1.773  -8.531  1.00 53.02  ? 19  ASN D C   1 
ATOM   2346 O  O   . ASN C 1 19  ? -20.155 -2.404  -7.486  1.00 51.55  ? 19  ASN D O   1 
ATOM   2347 C  CB  . ASN C 1 19  ? -21.505 0.382   -8.125  1.00 54.46  ? 19  ASN D CB  1 
ATOM   2348 C  CG  . ASN C 1 19  ? -22.778 1.189   -8.081  1.00 72.17  ? 19  ASN D CG  1 
ATOM   2349 O  OD1 . ASN C 1 19  ? -23.467 1.259   -7.050  1.00 64.59  ? 19  ASN D OD1 1 
ATOM   2350 N  ND2 . ASN C 1 19  ? -23.110 1.819   -9.199  1.00 58.42  ? 19  ASN D ND2 1 
ATOM   2351 N  N   . PHE C 1 20  ? -19.483 -1.690  -9.543  1.00 48.30  ? 20  PHE D N   1 
ATOM   2352 C  CA  . PHE C 1 20  ? -18.149 -2.295  -9.580  1.00 47.48  ? 20  PHE D CA  1 
ATOM   2353 C  C   . PHE C 1 20  ? -17.166 -1.204  -9.996  1.00 54.41  ? 20  PHE D C   1 
ATOM   2354 O  O   . PHE C 1 20  ? -17.438 -0.455  -10.940 1.00 54.09  ? 20  PHE D O   1 
ATOM   2355 C  CB  . PHE C 1 20  ? -18.072 -3.451  -10.607 1.00 47.16  ? 20  PHE D CB  1 
ATOM   2356 C  CG  . PHE C 1 20  ? -19.061 -4.578  -10.434 1.00 46.88  ? 20  PHE D CG  1 
ATOM   2357 C  CD1 . PHE C 1 20  ? -20.349 -4.481  -10.952 1.00 48.20  ? 20  PHE D CD1 1 
ATOM   2358 C  CD2 . PHE C 1 20  ? -18.698 -5.747  -9.775  1.00 48.33  ? 20  PHE D CD2 1 
ATOM   2359 C  CE1 . PHE C 1 20  ? -21.269 -5.521  -10.785 1.00 48.11  ? 20  PHE D CE1 1 
ATOM   2360 C  CE2 . PHE C 1 20  ? -19.620 -6.787  -9.603  1.00 50.02  ? 20  PHE D CE2 1 
ATOM   2361 C  CZ  . PHE C 1 20  ? -20.896 -6.671  -10.121 1.00 47.70  ? 20  PHE D CZ  1 
ATOM   2362 N  N   . GLU C 1 21  ? -16.031 -1.111  -9.299  1.00 53.84  ? 21  GLU D N   1 
ATOM   2363 C  CA  . GLU C 1 21  ? -14.987 -0.141  -9.624  1.00 56.48  ? 21  GLU D CA  1 
ATOM   2364 C  C   . GLU C 1 21  ? -13.610 -0.767  -9.466  1.00 59.92  ? 21  GLU D C   1 
ATOM   2365 O  O   . GLU C 1 21  ? -13.327 -1.380  -8.438  1.00 58.76  ? 21  GLU D O   1 
ATOM   2366 C  CB  . GLU C 1 21  ? -15.117 1.147   -8.789  1.00 60.40  ? 21  GLU D CB  1 
ATOM   2367 C  CG  . GLU C 1 21  ? -14.269 2.295   -9.320  1.00 74.02  ? 21  GLU D CG  1 
ATOM   2368 C  CD  . GLU C 1 21  ? -14.566 3.668   -8.747  1.00 103.88 ? 21  GLU D CD  1 
ATOM   2369 O  OE1 . GLU C 1 21  ? -13.609 4.338   -8.296  1.00 100.78 ? 21  GLU D OE1 1 
ATOM   2370 O  OE2 . GLU C 1 21  ? -15.749 4.082   -8.761  1.00 101.88 ? 21  GLU D OE2 1 
ATOM   2371 N  N   . GLN C 1 22  ? -12.770 -0.619  -10.498 1.00 57.85  ? 22  GLN D N   1 
ATOM   2372 C  CA  . GLN C 1 22  ? -11.398 -1.131  -10.520 1.00 59.49  ? 22  GLN D CA  1 
ATOM   2373 C  C   . GLN C 1 22  ? -10.450 -0.026  -10.994 1.00 68.01  ? 22  GLN D C   1 
ATOM   2374 O  O   . GLN C 1 22  ? -10.442 0.329   -12.177 1.00 67.32  ? 22  GLN D O   1 
ATOM   2375 C  CB  . GLN C 1 22  ? -11.308 -2.383  -11.408 1.00 58.60  ? 22  GLN D CB  1 
ATOM   2376 C  CG  . GLN C 1 22  ? -10.040 -3.213  -11.205 1.00 60.18  ? 22  GLN D CG  1 
ATOM   2377 C  CD  . GLN C 1 22  ? -9.989  -4.419  -12.116 1.00 70.86  ? 22  GLN D CD  1 
ATOM   2378 O  OE1 . GLN C 1 22  ? -10.576 -4.450  -13.203 1.00 67.60  ? 22  GLN D OE1 1 
ATOM   2379 N  NE2 . GLN C 1 22  ? -9.283  -5.447  -11.693 1.00 60.77  ? 22  GLN D NE2 1 
ATOM   2380 N  N   . LYS C 1 23  ? -9.677  0.535   -10.052 1.00 69.75  ? 23  LYS D N   1 
ATOM   2381 C  CA  . LYS C 1 23  ? -8.699  1.606   -10.297 1.00 74.27  ? 23  LYS D CA  1 
ATOM   2382 C  C   . LYS C 1 23  ? -7.541  1.186   -11.208 1.00 81.27  ? 23  LYS D C   1 
ATOM   2383 O  O   . LYS C 1 23  ? -7.090  1.995   -12.020 1.00 83.73  ? 23  LYS D O   1 
ATOM   2384 C  CB  . LYS C 1 23  ? -8.172  2.189   -8.976  1.00 79.58  ? 23  LYS D CB  1 
ATOM   2385 C  CG  . LYS C 1 23  ? -9.179  3.093   -8.270  1.00 96.49  ? 23  LYS D CG  1 
ATOM   2386 C  CD  . LYS C 1 23  ? -8.555  3.841   -7.103  1.00 110.84 ? 23  LYS D CD  1 
ATOM   2387 C  CE  . LYS C 1 23  ? -9.542  4.777   -6.450  1.00 122.91 ? 23  LYS D CE  1 
ATOM   2388 N  NZ  . LYS C 1 23  ? -8.903  5.609   -5.398  1.00 135.01 ? 23  LYS D NZ  1 
ATOM   2389 N  N   . GLU C 1 24  ? -7.063  -0.066  -11.075 1.00 78.02  ? 24  GLU D N   1 
ATOM   2390 C  CA  . GLU C 1 24  ? -5.965  -0.606  -11.886 1.00 80.20  ? 24  GLU D CA  1 
ATOM   2391 C  C   . GLU C 1 24  ? -6.250  -2.028  -12.345 1.00 82.36  ? 24  GLU D C   1 
ATOM   2392 O  O   . GLU C 1 24  ? -6.801  -2.817  -11.576 1.00 79.39  ? 24  GLU D O   1 
ATOM   2393 C  CB  . GLU C 1 24  ? -4.627  -0.538  -11.134 1.00 85.27  ? 24  GLU D CB  1 
ATOM   2394 C  CG  . GLU C 1 24  ? -3.850  0.747   -11.382 1.00 101.36 ? 24  GLU D CG  1 
ATOM   2395 C  CD  . GLU C 1 24  ? -3.908  1.812   -10.300 1.00 123.91 ? 24  GLU D CD  1 
ATOM   2396 O  OE1 . GLU C 1 24  ? -4.808  1.748   -9.432  1.00 119.49 ? 24  GLU D OE1 1 
ATOM   2397 O  OE2 . GLU C 1 24  ? -3.049  2.722   -10.329 1.00 119.57 ? 24  GLU D OE2 1 
ATOM   2398 N  N   . SER C 1 25  ? -5.851  -2.347  -13.597 1.00 80.77  ? 25  SER D N   1 
ATOM   2399 C  CA  . SER C 1 25  ? -6.031  -3.633  -14.289 1.00 79.08  ? 25  SER D CA  1 
ATOM   2400 C  C   . SER C 1 25  ? -5.738  -4.863  -13.420 1.00 82.71  ? 25  SER D C   1 
ATOM   2401 O  O   . SER C 1 25  ? -6.595  -5.744  -13.309 1.00 80.02  ? 25  SER D O   1 
ATOM   2402 C  CB  . SER C 1 25  ? -5.210  -3.673  -15.581 1.00 84.75  ? 25  SER D CB  1 
ATOM   2403 O  OG  . SER C 1 25  ? -3.813  -3.619  -15.334 1.00 96.09  ? 25  SER D OG  1 
ATOM   2404 N  N   . ASN C 1 26  ? -4.552  -4.899  -12.780 1.00 81.97  ? 26  ASN D N   1 
ATOM   2405 C  CA  . ASN C 1 26  ? -4.140  -5.996  -11.900 1.00 82.11  ? 26  ASN D CA  1 
ATOM   2406 C  C   . ASN C 1 26  ? -4.432  -5.681  -10.417 1.00 84.86  ? 26  ASN D C   1 
ATOM   2407 O  O   . ASN C 1 26  ? -3.688  -6.103  -9.527  1.00 87.05  ? 26  ASN D O   1 
ATOM   2408 C  CB  . ASN C 1 26  ? -2.669  -6.391  -12.152 1.00 89.27  ? 26  ASN D CB  1 
ATOM   2409 C  CG  . ASN C 1 26  ? -1.655  -5.259  -12.158 1.00 119.27 ? 26  ASN D CG  1 
ATOM   2410 O  OD1 . ASN C 1 26  ? -1.798  -4.232  -11.479 1.00 118.72 ? 26  ASN D OD1 1 
ATOM   2411 N  ND2 . ASN C 1 26  ? -0.585  -5.436  -12.921 1.00 110.51 ? 26  ASN D ND2 1 
ATOM   2412 N  N   . GLY C 1 27  ? -5.536  -4.968  -10.178 1.00 77.79  ? 27  GLY D N   1 
ATOM   2413 C  CA  . GLY C 1 27  ? -5.964  -4.559  -8.846  1.00 76.39  ? 27  GLY D CA  1 
ATOM   2414 C  C   . GLY C 1 27  ? -7.328  -5.071  -8.421  1.00 73.65  ? 27  GLY D C   1 
ATOM   2415 O  O   . GLY C 1 27  ? -8.039  -5.689  -9.222  1.00 71.17  ? 27  GLY D O   1 
ATOM   2416 N  N   . PRO C 1 28  ? -7.725  -4.834  -7.148  1.00 67.33  ? 28  PRO D N   1 
ATOM   2417 C  CA  . PRO C 1 28  ? -9.035  -5.327  -6.691  1.00 63.63  ? 28  PRO D CA  1 
ATOM   2418 C  C   . PRO C 1 28  ? -10.240 -4.531  -7.200  1.00 62.92  ? 28  PRO D C   1 
ATOM   2419 O  O   . PRO C 1 28  ? -10.133 -3.344  -7.525  1.00 63.11  ? 28  PRO D O   1 
ATOM   2420 C  CB  . PRO C 1 28  ? -8.927  -5.283  -5.167  1.00 66.70  ? 28  PRO D CB  1 
ATOM   2421 C  CG  . PRO C 1 28  ? -7.932  -4.215  -4.886  1.00 74.36  ? 28  PRO D CG  1 
ATOM   2422 C  CD  . PRO C 1 28  ? -6.997  -4.134  -6.064  1.00 71.19  ? 28  PRO D CD  1 
ATOM   2423 N  N   . VAL C 1 29  ? -11.394 -5.203  -7.259  1.00 55.26  ? 29  VAL D N   1 
ATOM   2424 C  CA  . VAL C 1 29  ? -12.660 -4.601  -7.671  1.00 52.45  ? 29  VAL D CA  1 
ATOM   2425 C  C   . VAL C 1 29  ? -13.490 -4.313  -6.415  1.00 56.83  ? 29  VAL D C   1 
ATOM   2426 O  O   . VAL C 1 29  ? -13.721 -5.214  -5.601  1.00 55.60  ? 29  VAL D O   1 
ATOM   2427 C  CB  . VAL C 1 29  ? -13.446 -5.469  -8.704  1.00 52.91  ? 29  VAL D CB  1 
ATOM   2428 C  CG1 . VAL C 1 29  ? -14.754 -4.793  -9.123  1.00 51.02  ? 29  VAL D CG1 1 
ATOM   2429 C  CG2 . VAL C 1 29  ? -12.592 -5.792  -9.930  1.00 53.04  ? 29  VAL D CG2 1 
ATOM   2430 N  N   . LYS C 1 30  ? -13.931 -3.055  -6.268  1.00 55.52  ? 30  LYS D N   1 
ATOM   2431 C  CA  . LYS C 1 30  ? -14.811 -2.619  -5.187  1.00 56.42  ? 30  LYS D CA  1 
ATOM   2432 C  C   . LYS C 1 30  ? -16.248 -2.859  -5.671  1.00 58.71  ? 30  LYS D C   1 
ATOM   2433 O  O   . LYS C 1 30  ? -16.605 -2.399  -6.754  1.00 57.91  ? 30  LYS D O   1 
ATOM   2434 C  CB  . LYS C 1 30  ? -14.572 -1.129  -4.869  1.00 61.98  ? 30  LYS D CB  1 
ATOM   2435 C  CG  . LYS C 1 30  ? -15.241 -0.638  -3.589  1.00 81.88  ? 30  LYS D CG  1 
ATOM   2436 C  CD  . LYS C 1 30  ? -14.826 0.794   -3.242  1.00 96.82  ? 30  LYS D CD  1 
ATOM   2437 C  CE  . LYS C 1 30  ? -15.826 1.850   -3.670  1.00 105.72 ? 30  LYS D CE  1 
ATOM   2438 N  NZ  . LYS C 1 30  ? -17.010 1.907   -2.767  1.00 111.35 ? 30  LYS D NZ  1 
ATOM   2439 N  N   . VAL C 1 31  ? -17.047 -3.627  -4.914  1.00 54.82  ? 31  VAL D N   1 
ATOM   2440 C  CA  . VAL C 1 31  ? -18.434 -3.907  -5.287  1.00 53.23  ? 31  VAL D CA  1 
ATOM   2441 C  C   . VAL C 1 31  ? -19.353 -3.444  -4.147  1.00 57.31  ? 31  VAL D C   1 
ATOM   2442 O  O   . VAL C 1 31  ? -19.200 -3.855  -2.994  1.00 57.49  ? 31  VAL D O   1 
ATOM   2443 C  CB  . VAL C 1 31  ? -18.732 -5.339  -5.851  1.00 56.08  ? 31  VAL D CB  1 
ATOM   2444 C  CG1 . VAL C 1 31  ? -17.573 -6.318  -5.679  1.00 56.09  ? 31  VAL D CG1 1 
ATOM   2445 C  CG2 . VAL C 1 31  ? -20.074 -5.923  -5.403  1.00 55.21  ? 31  VAL D CG2 1 
ATOM   2446 N  N   . TRP C 1 32  ? -20.249 -2.503  -4.475  1.00 53.18  ? 32  TRP D N   1 
ATOM   2447 C  CA  . TRP C 1 32  ? -21.155 -1.888  -3.511  1.00 54.64  ? 32  TRP D CA  1 
ATOM   2448 C  C   . TRP C 1 32  ? -22.524 -1.538  -4.106  1.00 56.80  ? 32  TRP D C   1 
ATOM   2449 O  O   . TRP C 1 32  ? -22.687 -1.508  -5.325  1.00 54.10  ? 32  TRP D O   1 
ATOM   2450 C  CB  . TRP C 1 32  ? -20.488 -0.661  -2.836  1.00 56.14  ? 32  TRP D CB  1 
ATOM   2451 C  CG  . TRP C 1 32  ? -20.508 0.584   -3.678  1.00 58.26  ? 32  TRP D CG  1 
ATOM   2452 C  CD1 . TRP C 1 32  ? -21.369 1.635   -3.564  1.00 63.07  ? 32  TRP D CD1 1 
ATOM   2453 C  CD2 . TRP C 1 32  ? -19.662 0.877   -4.797  1.00 57.61  ? 32  TRP D CD2 1 
ATOM   2454 N  NE1 . TRP C 1 32  ? -21.094 2.580   -4.522  1.00 63.24  ? 32  TRP D NE1 1 
ATOM   2455 C  CE2 . TRP C 1 32  ? -20.056 2.137   -5.301  1.00 63.23  ? 32  TRP D CE2 1 
ATOM   2456 C  CE3 . TRP C 1 32  ? -18.592 0.205   -5.414  1.00 57.83  ? 32  TRP D CE3 1 
ATOM   2457 C  CZ2 . TRP C 1 32  ? -19.419 2.740   -6.393  1.00 63.18  ? 32  TRP D CZ2 1 
ATOM   2458 C  CZ3 . TRP C 1 32  ? -17.974 0.794   -6.508  1.00 59.81  ? 32  TRP D CZ3 1 
ATOM   2459 C  CH2 . TRP C 1 32  ? -18.385 2.046   -6.987  1.00 62.14  ? 32  TRP D CH2 1 
ATOM   2460 N  N   . GLY C 1 33  ? -23.489 -1.280  -3.228  1.00 54.54  ? 33  GLY D N   1 
ATOM   2461 C  CA  . GLY C 1 33  ? -24.852 -0.935  -3.610  1.00 54.73  ? 33  GLY D CA  1 
ATOM   2462 C  C   . GLY C 1 33  ? -25.869 -1.522  -2.661  1.00 60.92  ? 33  GLY D C   1 
ATOM   2463 O  O   . GLY C 1 33  ? -25.516 -1.927  -1.550  1.00 61.78  ? 33  GLY D O   1 
ATOM   2464 N  N   . SER C 1 34  ? -27.139 -1.580  -3.087  1.00 58.92  ? 34  SER D N   1 
ATOM   2465 C  CA  . SER C 1 34  ? -28.204 -2.105  -2.239  1.00 60.62  ? 34  SER D CA  1 
ATOM   2466 C  C   . SER C 1 34  ? -29.169 -3.027  -2.963  1.00 63.31  ? 34  SER D C   1 
ATOM   2467 O  O   . SER C 1 34  ? -29.444 -2.831  -4.147  1.00 62.25  ? 34  SER D O   1 
ATOM   2468 C  CB  . SER C 1 34  ? -28.961 -0.967  -1.564  1.00 68.38  ? 34  SER D CB  1 
ATOM   2469 O  OG  . SER C 1 34  ? -29.557 -1.414  -0.357  1.00 83.03  ? 34  SER D OG  1 
ATOM   2470 N  N   . ILE C 1 35  ? -29.662 -4.048  -2.241  1.00 59.72  ? 35  ILE D N   1 
ATOM   2471 C  CA  . ILE C 1 35  ? -30.644 -5.036  -2.699  1.00 59.17  ? 35  ILE D CA  1 
ATOM   2472 C  C   . ILE C 1 35  ? -31.797 -5.068  -1.675  1.00 66.39  ? 35  ILE D C   1 
ATOM   2473 O  O   . ILE C 1 35  ? -31.549 -5.181  -0.467  1.00 66.36  ? 35  ILE D O   1 
ATOM   2474 C  CB  . ILE C 1 35  ? -30.018 -6.454  -2.911  1.00 60.36  ? 35  ILE D CB  1 
ATOM   2475 C  CG1 . ILE C 1 35  ? -28.752 -6.414  -3.814  1.00 58.50  ? 35  ILE D CG1 1 
ATOM   2476 C  CG2 . ILE C 1 35  ? -31.061 -7.431  -3.487  1.00 61.54  ? 35  ILE D CG2 1 
ATOM   2477 C  CD1 . ILE C 1 35  ? -27.755 -7.543  -3.586  1.00 62.74  ? 35  ILE D CD1 1 
ATOM   2478 N  N   . LYS C 1 36  ? -33.048 -4.950  -2.156  1.00 65.33  ? 36  LYS D N   1 
ATOM   2479 C  CA  . LYS C 1 36  ? -34.240 -4.992  -1.300  1.00 68.69  ? 36  LYS D CA  1 
ATOM   2480 C  C   . LYS C 1 36  ? -35.173 -6.156  -1.681  1.00 71.89  ? 36  LYS D C   1 
ATOM   2481 O  O   . LYS C 1 36  ? -34.928 -6.823  -2.690  1.00 68.20  ? 36  LYS D O   1 
ATOM   2482 C  CB  . LYS C 1 36  ? -34.973 -3.629  -1.256  1.00 74.08  ? 36  LYS D CB  1 
ATOM   2483 C  CG  . LYS C 1 36  ? -35.501 -3.130  -2.607  1.00 86.08  ? 36  LYS D CG  1 
ATOM   2484 C  CD  . LYS C 1 36  ? -36.319 -1.851  -2.456  1.00 96.49  ? 36  LYS D CD  1 
ATOM   2485 C  CE  . LYS C 1 36  ? -36.775 -1.301  -3.783  1.00 106.61 ? 36  LYS D CE  1 
ATOM   2486 N  NZ  . LYS C 1 36  ? -37.620 -0.090  -3.617  1.00 120.09 ? 36  LYS D NZ  1 
ATOM   2487 N  N   . GLY C 1 37  ? -36.189 -6.403  -0.843  1.00 71.13  ? 37  GLY D N   1 
ATOM   2488 C  CA  . GLY C 1 37  ? -37.198 -7.449  -1.025  1.00 72.38  ? 37  GLY D CA  1 
ATOM   2489 C  C   . GLY C 1 37  ? -36.751 -8.849  -0.648  1.00 74.06  ? 37  GLY D C   1 
ATOM   2490 O  O   . GLY C 1 37  ? -37.435 -9.835  -0.951  1.00 74.60  ? 37  GLY D O   1 
ATOM   2491 N  N   . LEU C 1 38  ? -35.620 -8.926  0.051   1.00 67.87  ? 38  LEU D N   1 
ATOM   2492 C  CA  . LEU C 1 38  ? -34.931 -10.137 0.486   1.00 67.08  ? 38  LEU D CA  1 
ATOM   2493 C  C   . LEU C 1 38  ? -35.448 -10.653 1.830   1.00 76.32  ? 38  LEU D C   1 
ATOM   2494 O  O   . LEU C 1 38  ? -35.958 -9.875  2.634   1.00 78.89  ? 38  LEU D O   1 
ATOM   2495 C  CB  . LEU C 1 38  ? -33.440 -9.761  0.633   1.00 63.97  ? 38  LEU D CB  1 
ATOM   2496 C  CG  . LEU C 1 38  ? -32.334 -10.499 -0.160  1.00 64.72  ? 38  LEU D CG  1 
ATOM   2497 C  CD1 . LEU C 1 38  ? -32.788 -11.014 -1.492  1.00 62.38  ? 38  LEU D CD1 1 
ATOM   2498 C  CD2 . LEU C 1 38  ? -31.116 -9.618  -0.333  1.00 64.91  ? 38  LEU D CD2 1 
ATOM   2499 N  N   . THR C 1 39  ? -35.291 -11.962 2.085   1.00 74.13  ? 39  THR D N   1 
ATOM   2500 C  CA  . THR C 1 39  ? -35.639 -12.562 3.378   1.00 77.97  ? 39  THR D CA  1 
ATOM   2501 C  C   . THR C 1 39  ? -34.399 -12.376 4.265   1.00 81.45  ? 39  THR D C   1 
ATOM   2502 O  O   . THR C 1 39  ? -33.281 -12.406 3.747   1.00 78.42  ? 39  THR D O   1 
ATOM   2503 C  CB  . THR C 1 39  ? -36.047 -14.042 3.228   1.00 86.31  ? 39  THR D CB  1 
ATOM   2504 O  OG1 . THR C 1 39  ? -35.052 -14.743 2.479   1.00 82.86  ? 39  THR D OG1 1 
ATOM   2505 C  CG2 . THR C 1 39  ? -37.414 -14.212 2.568   1.00 86.21  ? 39  THR D CG2 1 
ATOM   2506 N  N   . GLU C 1 40  ? -34.586 -12.130 5.567   1.00 80.39  ? 40  GLU D N   1 
ATOM   2507 C  CA  . GLU C 1 40  ? -33.477 -11.917 6.512   1.00 79.97  ? 40  GLU D CA  1 
ATOM   2508 C  C   . GLU C 1 40  ? -32.477 -13.083 6.504   1.00 82.45  ? 40  GLU D C   1 
ATOM   2509 O  O   . GLU C 1 40  ? -32.877 -14.244 6.413   1.00 84.03  ? 40  GLU D O   1 
ATOM   2510 C  CB  . GLU C 1 40  ? -34.005 -11.659 7.934   1.00 85.59  ? 40  GLU D CB  1 
ATOM   2511 C  CG  . GLU C 1 40  ? -33.015 -10.929 8.834   1.00 90.82  ? 40  GLU D CG  1 
ATOM   2512 C  CD  . GLU C 1 40  ? -33.400 -10.800 10.297  1.00 105.79 ? 40  GLU D CD  1 
ATOM   2513 O  OE1 . GLU C 1 40  ? -34.615 -10.798 10.603  1.00 91.04  ? 40  GLU D OE1 1 
ATOM   2514 O  OE2 . GLU C 1 40  ? -32.479 -10.689 11.140  1.00 91.84  ? 40  GLU D OE2 1 
ATOM   2515 N  N   . GLY C 1 41  ? -31.193 -12.747 6.572   1.00 75.60  ? 41  GLY D N   1 
ATOM   2516 C  CA  . GLY C 1 41  ? -30.107 -13.716 6.555   1.00 73.38  ? 41  GLY D CA  1 
ATOM   2517 C  C   . GLY C 1 41  ? -29.221 -13.610 5.331   1.00 70.65  ? 41  GLY D C   1 
ATOM   2518 O  O   . GLY C 1 41  ? -29.363 -12.682 4.526   1.00 66.81  ? 41  GLY D O   1 
ATOM   2519 N  N   . LEU C 1 42  ? -28.304 -14.582 5.189   1.00 66.11  ? 42  LEU D N   1 
ATOM   2520 C  CA  . LEU C 1 42  ? -27.307 -14.674 4.123   1.00 62.36  ? 42  LEU D CA  1 
ATOM   2521 C  C   . LEU C 1 42  ? -27.872 -15.211 2.799   1.00 63.82  ? 42  LEU D C   1 
ATOM   2522 O  O   . LEU C 1 42  ? -28.644 -16.171 2.790   1.00 63.79  ? 42  LEU D O   1 
ATOM   2523 C  CB  . LEU C 1 42  ? -26.138 -15.557 4.593   1.00 63.10  ? 42  LEU D CB  1 
ATOM   2524 C  CG  . LEU C 1 42  ? -24.929 -14.878 5.281   1.00 67.79  ? 42  LEU D CG  1 
ATOM   2525 C  CD1 . LEU C 1 42  ? -25.319 -14.180 6.569   1.00 70.58  ? 42  LEU D CD1 1 
ATOM   2526 C  CD2 . LEU C 1 42  ? -23.884 -15.902 5.631   1.00 71.91  ? 42  LEU D CD2 1 
ATOM   2527 N  N   . HIS C 1 43  ? -27.455 -14.597 1.681   1.00 58.60  ? 43  HIS D N   1 
ATOM   2528 C  CA  . HIS C 1 43  ? -27.838 -15.014 0.338   1.00 57.77  ? 43  HIS D CA  1 
ATOM   2529 C  C   . HIS C 1 43  ? -26.600 -15.094 -0.537  1.00 58.65  ? 43  HIS D C   1 
ATOM   2530 O  O   . HIS C 1 43  ? -25.856 -14.115 -0.626  1.00 55.80  ? 43  HIS D O   1 
ATOM   2531 C  CB  . HIS C 1 43  ? -28.857 -14.033 -0.278  1.00 58.34  ? 43  HIS D CB  1 
ATOM   2532 C  CG  . HIS C 1 43  ? -30.181 -14.037 0.423   1.00 64.43  ? 43  HIS D CG  1 
ATOM   2533 N  ND1 . HIS C 1 43  ? -31.176 -14.936 0.083   1.00 67.55  ? 43  HIS D ND1 1 
ATOM   2534 C  CD2 . HIS C 1 43  ? -30.622 -13.263 1.440   1.00 67.80  ? 43  HIS D CD2 1 
ATOM   2535 C  CE1 . HIS C 1 43  ? -32.185 -14.679 0.899   1.00 69.45  ? 43  HIS D CE1 1 
ATOM   2536 N  NE2 . HIS C 1 43  ? -31.903 -13.674 1.723   1.00 70.04  ? 43  HIS D NE2 1 
ATOM   2537 N  N   . GLY C 1 44  ? -26.395 -16.248 -1.176  1.00 55.52  ? 44  GLY D N   1 
ATOM   2538 C  CA  . GLY C 1 44  ? -25.288 -16.475 -2.103  1.00 53.18  ? 44  GLY D CA  1 
ATOM   2539 C  C   . GLY C 1 44  ? -25.254 -15.407 -3.180  1.00 53.51  ? 44  GLY D C   1 
ATOM   2540 O  O   . GLY C 1 44  ? -26.299 -15.047 -3.731  1.00 51.15  ? 44  GLY D O   1 
ATOM   2541 N  N   . PHE C 1 45  ? -24.063 -14.831 -3.416  1.00 50.00  ? 45  PHE D N   1 
ATOM   2542 C  CA  . PHE C 1 45  ? -23.839 -13.748 -4.375  1.00 48.15  ? 45  PHE D CA  1 
ATOM   2543 C  C   . PHE C 1 45  ? -22.803 -14.232 -5.400  1.00 51.40  ? 45  PHE D C   1 
ATOM   2544 O  O   . PHE C 1 45  ? -21.628 -14.383 -5.062  1.00 49.69  ? 45  PHE D O   1 
ATOM   2545 C  CB  . PHE C 1 45  ? -23.343 -12.507 -3.604  1.00 49.83  ? 45  PHE D CB  1 
ATOM   2546 C  CG  . PHE C 1 45  ? -23.464 -11.150 -4.262  1.00 49.25  ? 45  PHE D CG  1 
ATOM   2547 C  CD1 . PHE C 1 45  ? -24.659 -10.746 -4.851  1.00 50.75  ? 45  PHE D CD1 1 
ATOM   2548 C  CD2 . PHE C 1 45  ? -22.436 -10.220 -4.161  1.00 50.69  ? 45  PHE D CD2 1 
ATOM   2549 C  CE1 . PHE C 1 45  ? -24.797 -9.463  -5.381  1.00 50.38  ? 45  PHE D CE1 1 
ATOM   2550 C  CE2 . PHE C 1 45  ? -22.574 -8.937  -4.695  1.00 52.40  ? 45  PHE D CE2 1 
ATOM   2551 C  CZ  . PHE C 1 45  ? -23.758 -8.566  -5.294  1.00 49.40  ? 45  PHE D CZ  1 
ATOM   2552 N  N   . HIS C 1 46  ? -23.252 -14.545 -6.631  1.00 48.05  ? 46  HIS D N   1 
ATOM   2553 C  CA  . HIS C 1 46  ? -22.354 -15.110 -7.644  1.00 48.20  ? 46  HIS D CA  1 
ATOM   2554 C  C   . HIS C 1 46  ? -22.415 -14.482 -9.023  1.00 48.96  ? 46  HIS D C   1 
ATOM   2555 O  O   . HIS C 1 46  ? -23.490 -14.091 -9.485  1.00 49.10  ? 46  HIS D O   1 
ATOM   2556 C  CB  . HIS C 1 46  ? -22.587 -16.627 -7.787  1.00 51.11  ? 46  HIS D CB  1 
ATOM   2557 C  CG  . HIS C 1 46  ? -22.335 -17.417 -6.541  1.00 56.51  ? 46  HIS D CG  1 
ATOM   2558 N  ND1 . HIS C 1 46  ? -23.362 -17.726 -5.666  1.00 59.62  ? 46  HIS D ND1 1 
ATOM   2559 C  CD2 . HIS C 1 46  ? -21.185 -17.957 -6.073  1.00 59.23  ? 46  HIS D CD2 1 
ATOM   2560 C  CE1 . HIS C 1 46  ? -22.802 -18.412 -4.681  1.00 60.54  ? 46  HIS D CE1 1 
ATOM   2561 N  NE2 . HIS C 1 46  ? -21.496 -18.581 -4.883  1.00 60.80  ? 46  HIS D NE2 1 
ATOM   2562 N  N   . VAL C 1 47  ? -21.252 -14.432 -9.706  1.00 44.60  ? 47  VAL D N   1 
ATOM   2563 C  CA  . VAL C 1 47  ? -21.183 -14.000 -11.104 1.00 43.10  ? 47  VAL D CA  1 
ATOM   2564 C  C   . VAL C 1 47  ? -21.324 -15.320 -11.876 1.00 47.19  ? 47  VAL D C   1 
ATOM   2565 O  O   . VAL C 1 47  ? -20.644 -16.298 -11.546 1.00 47.95  ? 47  VAL D O   1 
ATOM   2566 C  CB  . VAL C 1 47  ? -19.899 -13.210 -11.507 1.00 46.12  ? 47  VAL D CB  1 
ATOM   2567 C  CG1 . VAL C 1 47  ? -19.960 -12.773 -12.977 1.00 44.60  ? 47  VAL D CG1 1 
ATOM   2568 C  CG2 . VAL C 1 47  ? -19.679 -12.000 -10.601 1.00 45.57  ? 47  VAL D CG2 1 
ATOM   2569 N  N   . HIS C 1 48  ? -22.285 -15.372 -12.806 1.00 43.36  ? 48  HIS D N   1 
ATOM   2570 C  CA  . HIS C 1 48  ? -22.575 -16.533 -13.639 1.00 43.63  ? 48  HIS D CA  1 
ATOM   2571 C  C   . HIS C 1 48  ? -22.037 -16.269 -15.033 1.00 48.84  ? 48  HIS D C   1 
ATOM   2572 O  O   . HIS C 1 48  ? -21.889 -15.109 -15.427 1.00 48.28  ? 48  HIS D O   1 
ATOM   2573 C  CB  . HIS C 1 48  ? -24.071 -16.885 -13.612 1.00 44.32  ? 48  HIS D CB  1 
ATOM   2574 C  CG  . HIS C 1 48  ? -24.525 -17.490 -12.313 1.00 48.29  ? 48  HIS D CG  1 
ATOM   2575 N  ND1 . HIS C 1 48  ? -25.030 -18.777 -12.252 1.00 51.91  ? 48  HIS D ND1 1 
ATOM   2576 C  CD2 . HIS C 1 48  ? -24.522 -16.967 -11.062 1.00 48.71  ? 48  HIS D CD2 1 
ATOM   2577 C  CE1 . HIS C 1 48  ? -25.332 -18.989 -10.982 1.00 51.56  ? 48  HIS D CE1 1 
ATOM   2578 N  NE2 . HIS C 1 48  ? -25.048 -17.926 -10.230 1.00 50.29  ? 48  HIS D NE2 1 
ATOM   2579 N  N   . GLU C 1 49  ? -21.686 -17.343 -15.752 1.00 46.08  ? 49  GLU D N   1 
ATOM   2580 C  CA  . GLU C 1 49  ? -21.012 -17.321 -17.039 1.00 46.02  ? 49  GLU D CA  1 
ATOM   2581 C  C   . GLU C 1 49  ? -21.691 -16.496 -18.145 1.00 49.79  ? 49  GLU D C   1 
ATOM   2582 O  O   . GLU C 1 49  ? -20.995 -15.741 -18.826 1.00 49.40  ? 49  GLU D O   1 
ATOM   2583 C  CB  . GLU C 1 49  ? -20.750 -18.759 -17.523 1.00 49.65  ? 49  GLU D CB  1 
ATOM   2584 C  CG  . GLU C 1 49  ? -19.772 -18.848 -18.686 1.00 54.67  ? 49  GLU D CG  1 
ATOM   2585 C  CD  . GLU C 1 49  ? -19.457 -20.225 -19.237 1.00 75.14  ? 49  GLU D CD  1 
ATOM   2586 O  OE1 . GLU C 1 49  ? -19.900 -21.234 -18.640 1.00 65.60  ? 49  GLU D OE1 1 
ATOM   2587 O  OE2 . GLU C 1 49  ? -18.768 -20.292 -20.281 1.00 68.83  ? 49  GLU D OE2 1 
ATOM   2588 N  N   . PHE C 1 50  ? -23.009 -16.647 -18.358 1.00 46.83  ? 50  PHE D N   1 
ATOM   2589 C  CA  . PHE C 1 50  ? -23.650 -15.957 -19.477 1.00 46.30  ? 50  PHE D CA  1 
ATOM   2590 C  C   . PHE C 1 50  ? -24.498 -14.761 -19.088 1.00 49.55  ? 50  PHE D C   1 
ATOM   2591 O  O   . PHE C 1 50  ? -25.211 -14.799 -18.085 1.00 48.83  ? 50  PHE D O   1 
ATOM   2592 C  CB  . PHE C 1 50  ? -24.466 -16.942 -20.343 1.00 49.33  ? 50  PHE D CB  1 
ATOM   2593 C  CG  . PHE C 1 50  ? -23.692 -18.191 -20.704 1.00 52.26  ? 50  PHE D CG  1 
ATOM   2594 C  CD1 . PHE C 1 50  ? -22.598 -18.128 -21.561 1.00 55.27  ? 50  PHE D CD1 1 
ATOM   2595 C  CD2 . PHE C 1 50  ? -24.021 -19.419 -20.141 1.00 55.35  ? 50  PHE D CD2 1 
ATOM   2596 C  CE1 . PHE C 1 50  ? -21.846 -19.273 -21.848 1.00 58.31  ? 50  PHE D CE1 1 
ATOM   2597 C  CE2 . PHE C 1 50  ? -23.282 -20.566 -20.445 1.00 60.16  ? 50  PHE D CE2 1 
ATOM   2598 C  CZ  . PHE C 1 50  ? -22.201 -20.486 -21.298 1.00 58.98  ? 50  PHE D CZ  1 
ATOM   2599 N  N   . GLY C 1 51  ? -24.418 -13.718 -19.917 1.00 44.70  ? 51  GLY D N   1 
ATOM   2600 C  CA  . GLY C 1 51  ? -25.209 -12.504 -19.780 1.00 43.73  ? 51  GLY D CA  1 
ATOM   2601 C  C   . GLY C 1 51  ? -26.496 -12.689 -20.551 1.00 48.92  ? 51  GLY D C   1 
ATOM   2602 O  O   . GLY C 1 51  ? -26.901 -11.815 -21.319 1.00 48.98  ? 51  GLY D O   1 
ATOM   2603 N  N   . ASP C 1 52  ? -27.106 -13.873 -20.383 1.00 46.40  ? 52  ASP D N   1 
ATOM   2604 C  CA  . ASP C 1 52  ? -28.313 -14.340 -21.058 1.00 47.81  ? 52  ASP D CA  1 
ATOM   2605 C  C   . ASP C 1 52  ? -29.470 -14.383 -20.055 1.00 53.16  ? 52  ASP D C   1 
ATOM   2606 O  O   . ASP C 1 52  ? -29.449 -15.189 -19.129 1.00 53.37  ? 52  ASP D O   1 
ATOM   2607 C  CB  . ASP C 1 52  ? -28.047 -15.736 -21.660 1.00 50.68  ? 52  ASP D CB  1 
ATOM   2608 C  CG  . ASP C 1 52  ? -29.089 -16.236 -22.642 1.00 60.94  ? 52  ASP D CG  1 
ATOM   2609 O  OD1 . ASP C 1 52  ? -30.289 -16.044 -22.383 1.00 61.30  ? 52  ASP D OD1 1 
ATOM   2610 O  OD2 . ASP C 1 52  ? -28.700 -16.832 -23.663 1.00 67.18  ? 52  ASP D OD2 1 
ATOM   2611 N  N   . ASN C 1 53  ? -30.462 -13.503 -20.245 1.00 50.54  ? 53  ASN D N   1 
ATOM   2612 C  CA  . ASN C 1 53  ? -31.659 -13.366 -19.409 1.00 50.93  ? 53  ASN D CA  1 
ATOM   2613 C  C   . ASN C 1 53  ? -32.954 -13.808 -20.169 1.00 57.51  ? 53  ASN D C   1 
ATOM   2614 O  O   . ASN C 1 53  ? -34.068 -13.508 -19.724 1.00 58.59  ? 53  ASN D O   1 
ATOM   2615 C  CB  . ASN C 1 53  ? -31.768 -11.902 -18.945 1.00 50.59  ? 53  ASN D CB  1 
ATOM   2616 C  CG  . ASN C 1 53  ? -32.857 -11.640 -17.921 1.00 74.58  ? 53  ASN D CG  1 
ATOM   2617 O  OD1 . ASN C 1 53  ? -32.832 -12.163 -16.802 1.00 67.27  ? 53  ASN D OD1 1 
ATOM   2618 N  ND2 . ASN C 1 53  ? -33.854 -10.838 -18.293 1.00 67.60  ? 53  ASN D ND2 1 
ATOM   2619 N  N   . THR C 1 54  ? -32.811 -14.530 -21.304 1.00 55.86  ? 54  THR D N   1 
ATOM   2620 C  CA  . THR C 1 54  ? -33.959 -14.966 -22.130 1.00 58.43  ? 54  THR D CA  1 
ATOM   2621 C  C   . THR C 1 54  ? -34.950 -15.892 -21.398 1.00 65.61  ? 54  THR D C   1 
ATOM   2622 O  O   . THR C 1 54  ? -36.150 -15.808 -21.660 1.00 67.45  ? 54  THR D O   1 
ATOM   2623 C  CB  . THR C 1 54  ? -33.513 -15.591 -23.455 1.00 63.32  ? 54  THR D CB  1 
ATOM   2624 O  OG1 . THR C 1 54  ? -32.758 -16.770 -23.190 1.00 64.45  ? 54  THR D OG1 1 
ATOM   2625 C  CG2 . THR C 1 54  ? -32.726 -14.630 -24.321 1.00 57.01  ? 54  THR D CG2 1 
ATOM   2626 N  N   . ALA C 1 55  ? -34.452 -16.764 -20.498 1.00 62.69  ? 55  ALA D N   1 
ATOM   2627 C  CA  . ALA C 1 55  ? -35.269 -17.691 -19.705 1.00 65.09  ? 55  ALA D CA  1 
ATOM   2628 C  C   . ALA C 1 55  ? -35.184 -17.303 -18.223 1.00 68.68  ? 55  ALA D C   1 
ATOM   2629 O  O   . ALA C 1 55  ? -35.232 -18.158 -17.332 1.00 70.49  ? 55  ALA D O   1 
ATOM   2630 C  CB  . ALA C 1 55  ? -34.784 -19.122 -19.919 1.00 67.46  ? 55  ALA D CB  1 
ATOM   2631 N  N   . GLY C 1 56  ? -35.059 -16.001 -17.981 1.00 62.35  ? 56  GLY D N   1 
ATOM   2632 C  CA  . GLY C 1 56  ? -34.898 -15.449 -16.648 1.00 60.31  ? 56  GLY D CA  1 
ATOM   2633 C  C   . GLY C 1 56  ? -33.475 -15.657 -16.175 1.00 62.20  ? 56  GLY D C   1 
ATOM   2634 O  O   . GLY C 1 56  ? -32.537 -15.645 -16.982 1.00 60.45  ? 56  GLY D O   1 
ATOM   2635 N  N   . CYS C 1 57  ? -33.310 -15.893 -14.868 1.00 58.27  ? 57  CYS D N   1 
ATOM   2636 C  CA  . CYS C 1 57  ? -32.007 -16.115 -14.253 1.00 56.54  ? 57  CYS D CA  1 
ATOM   2637 C  C   . CYS C 1 57  ? -31.415 -17.499 -14.578 1.00 59.88  ? 57  CYS D C   1 
ATOM   2638 O  O   . CYS C 1 57  ? -30.199 -17.670 -14.477 1.00 58.12  ? 57  CYS D O   1 
ATOM   2639 C  CB  . CYS C 1 57  ? -32.066 -15.845 -12.748 1.00 57.29  ? 57  CYS D CB  1 
ATOM   2640 S  SG  . CYS C 1 57  ? -32.526 -14.137 -12.327 1.00 60.26  ? 57  CYS D SG  1 
ATOM   2641 N  N   . THR C 1 58  ? -32.263 -18.460 -15.011 1.00 57.59  ? 58  THR D N   1 
ATOM   2642 C  CA  . THR C 1 58  ? -31.878 -19.833 -15.377 1.00 59.04  ? 58  THR D CA  1 
ATOM   2643 C  C   . THR C 1 58  ? -30.870 -19.863 -16.551 1.00 60.95  ? 58  THR D C   1 
ATOM   2644 O  O   . THR C 1 58  ? -29.945 -20.681 -16.551 1.00 60.25  ? 58  THR D O   1 
ATOM   2645 C  CB  . THR C 1 58  ? -33.133 -20.673 -15.721 1.00 73.18  ? 58  THR D CB  1 
ATOM   2646 O  OG1 . THR C 1 58  ? -34.245 -20.285 -14.904 1.00 75.46  ? 58  THR D OG1 1 
ATOM   2647 C  CG2 . THR C 1 58  ? -32.889 -22.172 -15.598 1.00 74.79  ? 58  THR D CG2 1 
ATOM   2648 N  N   . SER C 1 59  ? -31.070 -18.979 -17.548 1.00 56.59  ? 59  SER D N   1 
ATOM   2649 C  CA  . SER C 1 59  ? -30.243 -18.885 -18.759 1.00 55.26  ? 59  SER D CA  1 
ATOM   2650 C  C   . SER C 1 59  ? -28.845 -18.272 -18.513 1.00 56.20  ? 59  SER D C   1 
ATOM   2651 O  O   . SER C 1 59  ? -27.997 -18.329 -19.402 1.00 54.88  ? 59  SER D O   1 
ATOM   2652 C  CB  . SER C 1 59  ? -30.991 -18.163 -19.877 1.00 57.90  ? 59  SER D CB  1 
ATOM   2653 O  OG  . SER C 1 59  ? -31.771 -17.074 -19.413 1.00 64.31  ? 59  SER D OG  1 
ATOM   2654 N  N   . ALA C 1 60  ? -28.581 -17.762 -17.285 1.00 52.04  ? 60  ALA D N   1 
ATOM   2655 C  CA  . ALA C 1 60  ? -27.265 -17.224 -16.898 1.00 49.79  ? 60  ALA D CA  1 
ATOM   2656 C  C   . ALA C 1 60  ? -26.193 -18.325 -16.805 1.00 53.60  ? 60  ALA D C   1 
ATOM   2657 O  O   . ALA C 1 60  ? -25.002 -18.020 -16.820 1.00 51.78  ? 60  ALA D O   1 
ATOM   2658 C  CB  . ALA C 1 60  ? -27.364 -16.468 -15.585 1.00 49.29  ? 60  ALA D CB  1 
ATOM   2659 N  N   . GLY C 1 61  ? -26.630 -19.582 -16.728 1.00 52.68  ? 61  GLY D N   1 
ATOM   2660 C  CA  . GLY C 1 61  ? -25.761 -20.752 -16.692 1.00 54.09  ? 61  GLY D CA  1 
ATOM   2661 C  C   . GLY C 1 61  ? -25.073 -21.002 -15.364 1.00 56.63  ? 61  GLY D C   1 
ATOM   2662 O  O   . GLY C 1 61  ? -25.564 -20.555 -14.324 1.00 54.97  ? 61  GLY D O   1 
ATOM   2663 N  N   . PRO C 1 62  ? -23.930 -21.732 -15.354 1.00 54.05  ? 62  PRO D N   1 
ATOM   2664 C  CA  . PRO C 1 62  ? -23.259 -22.014 -14.077 1.00 54.46  ? 62  PRO D CA  1 
ATOM   2665 C  C   . PRO C 1 62  ? -22.435 -20.835 -13.566 1.00 56.85  ? 62  PRO D C   1 
ATOM   2666 O  O   . PRO C 1 62  ? -22.408 -19.781 -14.204 1.00 54.38  ? 62  PRO D O   1 
ATOM   2667 C  CB  . PRO C 1 62  ? -22.381 -23.219 -14.416 1.00 58.86  ? 62  PRO D CB  1 
ATOM   2668 C  CG  . PRO C 1 62  ? -22.024 -23.016 -15.833 1.00 62.93  ? 62  PRO D CG  1 
ATOM   2669 C  CD  . PRO C 1 62  ? -23.204 -22.351 -16.486 1.00 57.26  ? 62  PRO D CD  1 
ATOM   2670 N  N   . HIS C 1 63  ? -21.764 -21.019 -12.412 1.00 55.34  ? 63  HIS D N   1 
ATOM   2671 C  CA  . HIS C 1 63  ? -20.882 -20.018 -11.819 1.00 53.94  ? 63  HIS D CA  1 
ATOM   2672 C  C   . HIS C 1 63  ? -19.740 -19.743 -12.790 1.00 56.25  ? 63  HIS D C   1 
ATOM   2673 O  O   . HIS C 1 63  ? -19.224 -20.682 -13.407 1.00 57.53  ? 63  HIS D O   1 
ATOM   2674 C  CB  . HIS C 1 63  ? -20.318 -20.515 -10.475 1.00 56.43  ? 63  HIS D CB  1 
ATOM   2675 C  CG  . HIS C 1 63  ? -21.334 -20.653 -9.378  1.00 60.86  ? 63  HIS D CG  1 
ATOM   2676 N  ND1 . HIS C 1 63  ? -21.181 -21.594 -8.369  1.00 65.37  ? 63  HIS D ND1 1 
ATOM   2677 C  CD2 . HIS C 1 63  ? -22.470 -19.953 -9.148  1.00 61.98  ? 63  HIS D CD2 1 
ATOM   2678 C  CE1 . HIS C 1 63  ? -22.222 -21.440 -7.569  1.00 65.23  ? 63  HIS D CE1 1 
ATOM   2679 N  NE2 . HIS C 1 63  ? -23.030 -20.468 -7.997  1.00 63.70  ? 63  HIS D NE2 1 
ATOM   2680 N  N   . PHE C 1 64  ? -19.369 -18.463 -12.953 1.00 50.74  ? 64  PHE D N   1 
ATOM   2681 C  CA  . PHE C 1 64  ? -18.293 -18.079 -13.864 1.00 51.04  ? 64  PHE D CA  1 
ATOM   2682 C  C   . PHE C 1 64  ? -16.964 -18.661 -13.382 1.00 58.88  ? 64  PHE D C   1 
ATOM   2683 O  O   . PHE C 1 64  ? -16.501 -18.342 -12.277 1.00 56.62  ? 64  PHE D O   1 
ATOM   2684 C  CB  . PHE C 1 64  ? -18.253 -16.550 -14.073 1.00 50.30  ? 64  PHE D CB  1 
ATOM   2685 C  CG  . PHE C 1 64  ? -17.081 -16.007 -14.858 1.00 51.47  ? 64  PHE D CG  1 
ATOM   2686 C  CD1 . PHE C 1 64  ? -16.767 -16.513 -16.117 1.00 55.42  ? 64  PHE D CD1 1 
ATOM   2687 C  CD2 . PHE C 1 64  ? -16.325 -14.950 -14.365 1.00 52.97  ? 64  PHE D CD2 1 
ATOM   2688 C  CE1 . PHE C 1 64  ? -15.687 -16.003 -16.843 1.00 57.16  ? 64  PHE D CE1 1 
ATOM   2689 C  CE2 . PHE C 1 64  ? -15.249 -14.435 -15.098 1.00 56.28  ? 64  PHE D CE2 1 
ATOM   2690 C  CZ  . PHE C 1 64  ? -14.944 -14.958 -16.334 1.00 55.38  ? 64  PHE D CZ  1 
ATOM   2691 N  N   . ASN C 1 65  ? -16.408 -19.584 -14.194 1.00 60.17  ? 65  ASN D N   1 
ATOM   2692 C  CA  . ASN C 1 65  ? -15.162 -20.290 -13.914 1.00 63.77  ? 65  ASN D CA  1 
ATOM   2693 C  C   . ASN C 1 65  ? -14.321 -20.434 -15.194 1.00 72.72  ? 65  ASN D C   1 
ATOM   2694 O  O   . ASN C 1 65  ? -14.384 -21.476 -15.855 1.00 75.10  ? 65  ASN D O   1 
ATOM   2695 C  CB  . ASN C 1 65  ? -15.448 -21.651 -13.260 1.00 66.92  ? 65  ASN D CB  1 
ATOM   2696 C  CG  . ASN C 1 65  ? -14.309 -22.205 -12.440 1.00 87.07  ? 65  ASN D CG  1 
ATOM   2697 O  OD1 . ASN C 1 65  ? -13.599 -21.482 -11.724 1.00 73.47  ? 65  ASN D OD1 1 
ATOM   2698 N  ND2 . ASN C 1 65  ? -14.123 -23.513 -12.511 1.00 84.99  ? 65  ASN D ND2 1 
ATOM   2699 N  N   . PRO C 1 66  ? -13.542 -19.390 -15.572 1.00 70.58  ? 66  PRO D N   1 
ATOM   2700 C  CA  . PRO C 1 66  ? -12.735 -19.482 -16.805 1.00 73.13  ? 66  PRO D CA  1 
ATOM   2701 C  C   . PRO C 1 66  ? -11.553 -20.453 -16.741 1.00 81.91  ? 66  PRO D C   1 
ATOM   2702 O  O   . PRO C 1 66  ? -11.114 -20.926 -17.791 1.00 85.11  ? 66  PRO D O   1 
ATOM   2703 C  CB  . PRO C 1 66  ? -12.278 -18.040 -17.037 1.00 73.43  ? 66  PRO D CB  1 
ATOM   2704 C  CG  . PRO C 1 66  ? -12.258 -17.430 -15.688 1.00 76.06  ? 66  PRO D CG  1 
ATOM   2705 C  CD  . PRO C 1 66  ? -13.372 -18.077 -14.915 1.00 70.25  ? 66  PRO D CD  1 
ATOM   2706 N  N   . LEU C 1 67  ? -11.043 -20.747 -15.526 1.00 79.21  ? 67  LEU D N   1 
ATOM   2707 C  CA  . LEU C 1 67  ? -9.909  -21.652 -15.310 1.00 114.23 ? 67  LEU D CA  1 
ATOM   2708 C  C   . LEU C 1 67  ? -10.394 -23.068 -15.009 1.00 144.26 ? 67  LEU D C   1 
ATOM   2709 O  O   . LEU C 1 67  ? -9.663  -24.033 -15.228 1.00 109.79 ? 67  LEU D O   1 
ATOM   2710 C  CB  . LEU C 1 67  ? -9.011  -21.147 -14.164 1.00 114.49 ? 67  LEU D CB  1 
ATOM   2711 C  CG  . LEU C 1 67  ? -8.413  -19.745 -14.316 1.00 117.83 ? 67  LEU D CG  1 
ATOM   2712 C  CD1 . LEU C 1 67  ? -8.303  -19.058 -12.969 1.00 116.67 ? 67  LEU D CD1 1 
ATOM   2713 C  CD2 . LEU C 1 67  ? -7.066  -19.785 -15.026 1.00 123.22 ? 67  LEU D CD2 1 
ATOM   2714 N  N   . ARG C 1 79  ? -12.065 -21.775 -4.935  1.00 85.80  ? 79  ARG D N   1 
ATOM   2715 C  CA  . ARG C 1 79  ? -13.253 -20.989 -5.276  1.00 82.37  ? 79  ARG D CA  1 
ATOM   2716 C  C   . ARG C 1 79  ? -13.283 -20.565 -6.750  1.00 83.73  ? 79  ARG D C   1 
ATOM   2717 O  O   . ARG C 1 79  ? -12.226 -20.306 -7.331  1.00 84.15  ? 79  ARG D O   1 
ATOM   2718 C  CB  . ARG C 1 79  ? -13.391 -19.750 -4.356  1.00 81.32  ? 79  ARG D CB  1 
ATOM   2719 C  CG  . ARG C 1 79  ? -12.186 -18.793 -4.359  1.00 89.86  ? 79  ARG D CG  1 
ATOM   2720 C  CD  . ARG C 1 79  ? -12.568 -17.351 -4.061  1.00 93.37  ? 79  ARG D CD  1 
ATOM   2721 N  NE  . ARG C 1 79  ? -13.183 -16.682 -5.213  1.00 94.21  ? 79  ARG D NE  1 
ATOM   2722 C  CZ  . ARG C 1 79  ? -13.247 -15.363 -5.373  1.00 100.84 ? 79  ARG D CZ  1 
ATOM   2723 N  NH1 . ARG C 1 79  ? -12.725 -14.550 -4.461  1.00 84.76  ? 79  ARG D NH1 1 
ATOM   2724 N  NH2 . ARG C 1 79  ? -13.825 -14.846 -6.449  1.00 83.49  ? 79  ARG D NH2 1 
ATOM   2725 N  N   . HIS C 1 80  ? -14.494 -20.472 -7.345  1.00 77.79  ? 80  HIS D N   1 
ATOM   2726 C  CA  . HIS C 1 80  ? -14.665 -20.013 -8.731  1.00 75.65  ? 80  HIS D CA  1 
ATOM   2727 C  C   . HIS C 1 80  ? -14.430 -18.500 -8.764  1.00 72.11  ? 80  HIS D C   1 
ATOM   2728 O  O   . HIS C 1 80  ? -14.614 -17.835 -7.743  1.00 70.51  ? 80  HIS D O   1 
ATOM   2729 C  CB  . HIS C 1 80  ? -16.089 -20.303 -9.276  1.00 76.47  ? 80  HIS D CB  1 
ATOM   2730 C  CG  . HIS C 1 80  ? -16.588 -21.705 -9.092  1.00 83.15  ? 80  HIS D CG  1 
ATOM   2731 N  ND1 . HIS C 1 80  ? -17.807 -21.960 -8.484  1.00 85.32  ? 80  HIS D ND1 1 
ATOM   2732 C  CD2 . HIS C 1 80  ? -16.032 -22.882 -9.465  1.00 88.39  ? 80  HIS D CD2 1 
ATOM   2733 C  CE1 . HIS C 1 80  ? -17.945 -23.276 -8.492  1.00 87.77  ? 80  HIS D CE1 1 
ATOM   2734 N  NE2 . HIS C 1 80  ? -16.902 -23.874 -9.070  1.00 90.00  ? 80  HIS D NE2 1 
ATOM   2735 N  N   . VAL C 1 81  ? -14.070 -17.955 -9.941  1.00 64.61  ? 81  VAL D N   1 
ATOM   2736 C  CA  . VAL C 1 81  ? -13.847 -16.518 -10.143 1.00 61.64  ? 81  VAL D CA  1 
ATOM   2737 C  C   . VAL C 1 81  ? -15.110 -15.712 -9.746  1.00 64.48  ? 81  VAL D C   1 
ATOM   2738 O  O   . VAL C 1 81  ? -15.001 -14.740 -8.998  1.00 65.36  ? 81  VAL D O   1 
ATOM   2739 C  CB  . VAL C 1 81  ? -13.322 -16.200 -11.580 1.00 64.16  ? 81  VAL D CB  1 
ATOM   2740 C  CG1 . VAL C 1 81  ? -13.264 -14.696 -11.851 1.00 61.88  ? 81  VAL D CG1 1 
ATOM   2741 C  CG2 . VAL C 1 81  ? -11.949 -16.838 -11.819 1.00 66.49  ? 81  VAL D CG2 1 
ATOM   2742 N  N   . GLY C 1 82  ? -16.281 -16.188 -10.162 1.00 58.59  ? 82  GLY D N   1 
ATOM   2743 C  CA  . GLY C 1 82  ? -17.559 -15.552 -9.858  1.00 56.11  ? 82  GLY D CA  1 
ATOM   2744 C  C   . GLY C 1 82  ? -18.066 -15.605 -8.426  1.00 58.52  ? 82  GLY D C   1 
ATOM   2745 O  O   . GLY C 1 82  ? -19.028 -14.903 -8.103  1.00 55.11  ? 82  GLY D O   1 
ATOM   2746 N  N   . ASP C 1 83  ? -17.427 -16.413 -7.544  1.00 57.88  ? 83  ASP D N   1 
ATOM   2747 C  CA  . ASP C 1 83  ? -17.849 -16.568 -6.147  1.00 58.75  ? 83  ASP D CA  1 
ATOM   2748 C  C   . ASP C 1 83  ? -17.572 -15.327 -5.272  1.00 60.22  ? 83  ASP D C   1 
ATOM   2749 O  O   . ASP C 1 83  ? -16.449 -15.128 -4.810  1.00 60.68  ? 83  ASP D O   1 
ATOM   2750 C  CB  . ASP C 1 83  ? -17.238 -17.844 -5.530  1.00 64.31  ? 83  ASP D CB  1 
ATOM   2751 C  CG  . ASP C 1 83  ? -17.837 -19.158 -6.012  1.00 84.16  ? 83  ASP D CG  1 
ATOM   2752 O  OD1 . ASP C 1 83  ? -18.386 -19.189 -7.144  1.00 85.84  ? 83  ASP D OD1 1 
ATOM   2753 O  OD2 . ASP C 1 83  ? -17.745 -20.161 -5.266  1.00 93.65  ? 83  ASP D OD2 1 
ATOM   2754 N  N   . LEU C 1 84  ? -18.610 -14.507 -5.028  1.00 53.88  ? 84  LEU D N   1 
ATOM   2755 C  CA  . LEU C 1 84  ? -18.473 -13.295 -4.218  1.00 52.50  ? 84  LEU D CA  1 
ATOM   2756 C  C   . LEU C 1 84  ? -18.943 -13.482 -2.769  1.00 58.52  ? 84  LEU D C   1 
ATOM   2757 O  O   . LEU C 1 84  ? -19.126 -12.494 -2.052  1.00 58.71  ? 84  LEU D O   1 
ATOM   2758 C  CB  . LEU C 1 84  ? -19.179 -12.096 -4.877  1.00 50.28  ? 84  LEU D CB  1 
ATOM   2759 C  CG  . LEU C 1 84  ? -18.680 -11.641 -6.256  1.00 53.38  ? 84  LEU D CG  1 
ATOM   2760 C  CD1 . LEU C 1 84  ? -19.621 -10.621 -6.847  1.00 52.38  ? 84  LEU D CD1 1 
ATOM   2761 C  CD2 . LEU C 1 84  ? -17.279 -11.057 -6.181  1.00 56.49  ? 84  LEU D CD2 1 
ATOM   2762 N  N   . GLY C 1 85  ? -19.092 -14.740 -2.350  1.00 55.89  ? 85  GLY D N   1 
ATOM   2763 C  CA  . GLY C 1 85  ? -19.541 -15.101 -1.008  1.00 56.92  ? 85  GLY D CA  1 
ATOM   2764 C  C   . GLY C 1 85  ? -21.036 -14.918 -0.856  1.00 59.49  ? 85  GLY D C   1 
ATOM   2765 O  O   . GLY C 1 85  ? -21.805 -15.387 -1.699  1.00 58.86  ? 85  GLY D O   1 
ATOM   2766 N  N   . ASN C 1 86  ? -21.457 -14.220 0.209   1.00 56.55  ? 86  ASN D N   1 
ATOM   2767 C  CA  . ASN C 1 86  ? -22.868 -13.934 0.471   1.00 56.43  ? 86  ASN D CA  1 
ATOM   2768 C  C   . ASN C 1 86  ? -23.114 -12.440 0.604   1.00 60.12  ? 86  ASN D C   1 
ATOM   2769 O  O   . ASN C 1 86  ? -22.177 -11.663 0.760   1.00 60.23  ? 86  ASN D O   1 
ATOM   2770 C  CB  . ASN C 1 86  ? -23.349 -14.601 1.777   1.00 57.44  ? 86  ASN D CB  1 
ATOM   2771 C  CG  . ASN C 1 86  ? -23.176 -16.087 1.873   1.00 72.88  ? 86  ASN D CG  1 
ATOM   2772 O  OD1 . ASN C 1 86  ? -23.859 -16.847 1.191   1.00 60.36  ? 86  ASN D OD1 1 
ATOM   2773 N  ND2 . ASN C 1 86  ? -22.285 -16.535 2.764   1.00 65.04  ? 86  ASN D ND2 1 
ATOM   2774 N  N   . VAL C 1 87  ? -24.387 -12.051 0.544   1.00 56.69  ? 87  VAL D N   1 
ATOM   2775 C  CA  . VAL C 1 87  ? -24.884 -10.712 0.855   1.00 57.24  ? 87  VAL D CA  1 
ATOM   2776 C  C   . VAL C 1 87  ? -25.783 -10.913 2.081   1.00 61.48  ? 87  VAL D C   1 
ATOM   2777 O  O   . VAL C 1 87  ? -26.308 -12.016 2.247   1.00 61.22  ? 87  VAL D O   1 
ATOM   2778 C  CB  . VAL C 1 87  ? -25.584 -9.944  -0.293  1.00 59.87  ? 87  VAL D CB  1 
ATOM   2779 C  CG1 . VAL C 1 87  ? -24.575 -9.508  -1.345  1.00 57.57  ? 87  VAL D CG1 1 
ATOM   2780 C  CG2 . VAL C 1 87  ? -26.738 -10.739 -0.916  1.00 59.96  ? 87  VAL D CG2 1 
ATOM   2781 N  N   . THR C 1 88  ? -25.938 -9.901  2.946   1.00 59.56  ? 88  THR D N   1 
ATOM   2782 C  CA  . THR C 1 88  ? -26.766 -10.085 4.153   1.00 62.74  ? 88  THR D CA  1 
ATOM   2783 C  C   . THR C 1 88  ? -27.889 -9.040  4.258   1.00 68.08  ? 88  THR D C   1 
ATOM   2784 O  O   . THR C 1 88  ? -27.633 -7.839  4.374   1.00 67.98  ? 88  THR D O   1 
ATOM   2785 C  CB  . THR C 1 88  ? -25.911 -10.198 5.444   1.00 75.27  ? 88  THR D CB  1 
ATOM   2786 O  OG1 . THR C 1 88  ? -26.759 -10.343 6.598   1.00 79.44  ? 88  THR D OG1 1 
ATOM   2787 C  CG2 . THR C 1 88  ? -24.962 -9.032  5.643   1.00 74.91  ? 88  THR D CG2 1 
ATOM   2788 N  N   . ALA C 1 89  ? -29.138 -9.533  4.219   1.00 65.53  ? 89  ALA D N   1 
ATOM   2789 C  CA  . ALA C 1 89  ? -30.351 -8.729  4.354   1.00 67.53  ? 89  ALA D CA  1 
ATOM   2790 C  C   . ALA C 1 89  ? -30.661 -8.545  5.824   1.00 76.54  ? 89  ALA D C   1 
ATOM   2791 O  O   . ALA C 1 89  ? -30.459 -9.472  6.616   1.00 78.61  ? 89  ALA D O   1 
ATOM   2792 C  CB  . ALA C 1 89  ? -31.520 -9.427  3.675   1.00 68.08  ? 89  ALA D CB  1 
ATOM   2793 N  N   . ASP C 1 90  ? -31.157 -7.354  6.193   1.00 75.46  ? 90  ASP D N   1 
ATOM   2794 C  CA  . ASP C 1 90  ? -31.555 -7.058  7.569   1.00 79.17  ? 90  ASP D CA  1 
ATOM   2795 C  C   . ASP C 1 90  ? -33.035 -7.442  7.753   1.00 86.97  ? 90  ASP D C   1 
ATOM   2796 O  O   . ASP C 1 90  ? -33.623 -8.052  6.849   1.00 84.73  ? 90  ASP D O   1 
ATOM   2797 C  CB  . ASP C 1 90  ? -31.274 -5.577  7.934   1.00 81.86  ? 90  ASP D CB  1 
ATOM   2798 C  CG  . ASP C 1 90  ? -31.960 -4.498  7.097   1.00 88.24  ? 90  ASP D CG  1 
ATOM   2799 O  OD1 . ASP C 1 90  ? -33.040 -4.772  6.530   1.00 87.50  ? 90  ASP D OD1 1 
ATOM   2800 O  OD2 . ASP C 1 90  ? -31.429 -3.370  7.036   1.00 94.75  ? 90  ASP D OD2 1 
ATOM   2801 N  N   . LYS C 1 91  ? -33.636 -7.063  8.905   1.00 88.26  ? 91  LYS D N   1 
ATOM   2802 C  CA  . LYS C 1 91  ? -35.036 -7.318  9.266   1.00 91.94  ? 91  LYS D CA  1 
ATOM   2803 C  C   . LYS C 1 91  ? -36.057 -6.728  8.277   1.00 95.05  ? 91  LYS D C   1 
ATOM   2804 O  O   . LYS C 1 91  ? -37.188 -7.215  8.211   1.00 97.94  ? 91  LYS D O   1 
ATOM   2805 C  CB  . LYS C 1 91  ? -35.323 -6.840  10.704  1.00 99.80  ? 91  LYS D CB  1 
ATOM   2806 C  CG  . LYS C 1 91  ? -35.134 -5.334  10.927  1.00 121.46 ? 91  LYS D CG  1 
ATOM   2807 C  CD  . LYS C 1 91  ? -34.225 -5.028  12.108  1.00 136.36 ? 91  LYS D CD  1 
ATOM   2808 C  CE  . LYS C 1 91  ? -34.994 -4.621  13.341  1.00 152.96 ? 91  LYS D CE  1 
ATOM   2809 N  NZ  . LYS C 1 91  ? -34.082 -4.261  14.458  1.00 166.35 ? 91  LYS D NZ  1 
ATOM   2810 N  N   . ASP C 1 92  ? -35.661 -5.673  7.535   1.00 87.51  ? 92  ASP D N   1 
ATOM   2811 C  CA  . ASP C 1 92  ? -36.494 -4.984  6.545   1.00 86.40  ? 92  ASP D CA  1 
ATOM   2812 C  C   . ASP C 1 92  ? -36.293 -5.547  5.135   1.00 83.98  ? 92  ASP D C   1 
ATOM   2813 O  O   . ASP C 1 92  ? -36.987 -5.135  4.195   1.00 82.33  ? 92  ASP D O   1 
ATOM   2814 C  CB  . ASP C 1 92  ? -36.222 -3.468  6.581   1.00 89.33  ? 92  ASP D CB  1 
ATOM   2815 C  CG  . ASP C 1 92  ? -36.551 -2.816  7.915   1.00 106.05 ? 92  ASP D CG  1 
ATOM   2816 O  OD1 . ASP C 1 92  ? -37.738 -2.834  8.310   1.00 110.84 ? 92  ASP D OD1 1 
ATOM   2817 O  OD2 . ASP C 1 92  ? -35.623 -2.288  8.562   1.00 113.14 ? 92  ASP D OD2 1 
ATOM   2818 N  N   . GLY C 1 93  ? -35.381 -6.509  5.017   1.00 76.95  ? 93  GLY D N   1 
ATOM   2819 C  CA  . GLY C 1 93  ? -35.048 -7.159  3.756   1.00 73.53  ? 93  GLY D CA  1 
ATOM   2820 C  C   . GLY C 1 93  ? -34.096 -6.366  2.887   1.00 74.89  ? 93  GLY D C   1 
ATOM   2821 O  O   . GLY C 1 93  ? -34.021 -6.604  1.678   1.00 72.16  ? 93  GLY D O   1 
ATOM   2822 N  N   . VAL C 1 94  ? -33.358 -5.421  3.496   1.00 73.22  ? 94  VAL D N   1 
ATOM   2823 C  CA  . VAL C 1 94  ? -32.398 -4.575  2.786   1.00 71.07  ? 94  VAL D CA  1 
ATOM   2824 C  C   . VAL C 1 94  ? -30.968 -5.039  3.057   1.00 72.28  ? 94  VAL D C   1 
ATOM   2825 O  O   . VAL C 1 94  ? -30.548 -5.105  4.214   1.00 73.49  ? 94  VAL D O   1 
ATOM   2826 C  CB  . VAL C 1 94  ? -32.603 -3.056  3.076   1.00 77.82  ? 94  VAL D CB  1 
ATOM   2827 C  CG1 . VAL C 1 94  ? -31.566 -2.204  2.338   1.00 75.42  ? 94  VAL D CG1 1 
ATOM   2828 C  CG2 . VAL C 1 94  ? -34.017 -2.608  2.701   1.00 79.71  ? 94  VAL D CG2 1 
ATOM   2829 N  N   . ALA C 1 95  ? -30.236 -5.377  1.983   1.00 65.14  ? 95  ALA D N   1 
ATOM   2830 C  CA  . ALA C 1 95  ? -28.838 -5.786  2.053   1.00 62.94  ? 95  ALA D CA  1 
ATOM   2831 C  C   . ALA C 1 95  ? -27.965 -4.649  1.548   1.00 66.99  ? 95  ALA D C   1 
ATOM   2832 O  O   . ALA C 1 95  ? -28.080 -4.244  0.386   1.00 65.35  ? 95  ALA D O   1 
ATOM   2833 C  CB  . ALA C 1 95  ? -28.597 -7.055  1.242   1.00 61.06  ? 95  ALA D CB  1 
ATOM   2834 N  N   . ASP C 1 96  ? -27.144 -4.090  2.450   1.00 66.17  ? 96  ASP D N   1 
ATOM   2835 C  CA  . ASP C 1 96  ? -26.224 -3.005  2.143   1.00 66.41  ? 96  ASP D CA  1 
ATOM   2836 C  C   . ASP C 1 96  ? -24.935 -3.695  1.760   1.00 67.73  ? 96  ASP D C   1 
ATOM   2837 O  O   . ASP C 1 96  ? -24.300 -4.346  2.594   1.00 68.16  ? 96  ASP D O   1 
ATOM   2838 C  CB  . ASP C 1 96  ? -26.058 -2.067  3.354   1.00 72.83  ? 96  ASP D CB  1 
ATOM   2839 C  CG  . ASP C 1 96  ? -26.023 -0.581  3.033   1.00 91.79  ? 96  ASP D CG  1 
ATOM   2840 O  OD1 . ASP C 1 96  ? -26.626 -0.173  2.006   1.00 92.87  ? 96  ASP D OD1 1 
ATOM   2841 O  OD2 . ASP C 1 96  ? -25.411 0.181   3.819   1.00 101.74 ? 96  ASP D OD2 1 
ATOM   2842 N  N   . VAL C 1 97  ? -24.613 -3.663  0.462   1.00 60.58  ? 97  VAL D N   1 
ATOM   2843 C  CA  . VAL C 1 97  ? -23.459 -4.387  -0.050  1.00 57.94  ? 97  VAL D CA  1 
ATOM   2844 C  C   . VAL C 1 97  ? -22.192 -3.534  -0.080  1.00 61.21  ? 97  VAL D C   1 
ATOM   2845 O  O   . VAL C 1 97  ? -22.209 -2.385  -0.510  1.00 61.01  ? 97  VAL D O   1 
ATOM   2846 C  CB  . VAL C 1 97  ? -23.766 -5.047  -1.424  1.00 58.99  ? 97  VAL D CB  1 
ATOM   2847 C  CG1 . VAL C 1 97  ? -22.619 -5.948  -1.884  1.00 56.99  ? 97  VAL D CG1 1 
ATOM   2848 C  CG2 . VAL C 1 97  ? -25.077 -5.838  -1.362  1.00 58.66  ? 97  VAL D CG2 1 
ATOM   2849 N  N   . SER C 1 98  ? -21.098 -4.120  0.412   1.00 57.22  ? 98  SER D N   1 
ATOM   2850 C  CA  . SER C 1 98  ? -19.760 -3.553  0.412   1.00 57.65  ? 98  SER D CA  1 
ATOM   2851 C  C   . SER C 1 98  ? -18.829 -4.756  0.407   1.00 61.62  ? 98  SER D C   1 
ATOM   2852 O  O   . SER C 1 98  ? -18.809 -5.521  1.367   1.00 61.64  ? 98  SER D O   1 
ATOM   2853 C  CB  . SER C 1 98  ? -19.534 -2.673  1.639   1.00 63.71  ? 98  SER D CB  1 
ATOM   2854 O  OG  . SER C 1 98  ? -18.503 -1.734  1.384   1.00 73.85  ? 98  SER D OG  1 
ATOM   2855 N  N   . ILE C 1 99  ? -18.151 -4.986  -0.723  1.00 56.93  ? 99  ILE D N   1 
ATOM   2856 C  CA  . ILE C 1 99  ? -17.242 -6.116  -0.942  1.00 56.42  ? 99  ILE D CA  1 
ATOM   2857 C  C   . ILE C 1 99  ? -16.014 -5.619  -1.696  1.00 60.51  ? 99  ILE D C   1 
ATOM   2858 O  O   . ILE C 1 99  ? -16.137 -4.763  -2.575  1.00 59.95  ? 99  ILE D O   1 
ATOM   2859 C  CB  . ILE C 1 99  ? -17.978 -7.234  -1.777  1.00 57.54  ? 99  ILE D CB  1 
ATOM   2860 C  CG1 . ILE C 1 99  ? -19.058 -7.956  -0.958  1.00 57.73  ? 99  ILE D CG1 1 
ATOM   2861 C  CG2 . ILE C 1 99  ? -17.000 -8.264  -2.401  1.00 58.50  ? 99  ILE D CG2 1 
ATOM   2862 C  CD1 . ILE C 1 99  ? -20.080 -8.758  -1.784  1.00 58.18  ? 99  ILE D CD1 1 
ATOM   2863 N  N   . GLU C 1 100 ? -14.845 -6.195  -1.397  1.00 58.19  ? 100 GLU D N   1 
ATOM   2864 C  CA  . GLU C 1 100 ? -13.626 -5.939  -2.147  1.00 58.82  ? 100 GLU D CA  1 
ATOM   2865 C  C   . GLU C 1 100 ? -13.092 -7.305  -2.591  1.00 61.96  ? 100 GLU D C   1 
ATOM   2866 O  O   . GLU C 1 100 ? -12.827 -8.159  -1.744  1.00 63.24  ? 100 GLU D O   1 
ATOM   2867 C  CB  . GLU C 1 100 ? -12.598 -5.124  -1.347  1.00 63.15  ? 100 GLU D CB  1 
ATOM   2868 C  CG  . GLU C 1 100 ? -11.593 -4.425  -2.250  1.00 73.39  ? 100 GLU D CG  1 
ATOM   2869 C  CD  . GLU C 1 100 ? -10.671 -3.443  -1.555  1.00 95.75  ? 100 GLU D CD  1 
ATOM   2870 O  OE1 . GLU C 1 100 ? -10.893 -2.219  -1.699  1.00 92.35  ? 100 GLU D OE1 1 
ATOM   2871 O  OE2 . GLU C 1 100 ? -9.723  -3.896  -0.873  1.00 84.86  ? 100 GLU D OE2 1 
ATOM   2872 N  N   . ASP C 1 101 ? -13.032 -7.543  -3.912  1.00 56.53  ? 101 ASP D N   1 
ATOM   2873 C  CA  . ASP C 1 101 ? -12.575 -8.822  -4.455  1.00 56.06  ? 101 ASP D CA  1 
ATOM   2874 C  C   . ASP C 1 101 ? -11.367 -8.671  -5.388  1.00 60.86  ? 101 ASP D C   1 
ATOM   2875 O  O   . ASP C 1 101 ? -11.393 -7.847  -6.308  1.00 60.34  ? 101 ASP D O   1 
ATOM   2876 C  CB  . ASP C 1 101 ? -13.724 -9.563  -5.162  1.00 55.54  ? 101 ASP D CB  1 
ATOM   2877 C  CG  . ASP C 1 101 ? -13.385 -11.007 -5.467  1.00 66.12  ? 101 ASP D CG  1 
ATOM   2878 O  OD1 . ASP C 1 101 ? -13.557 -11.859 -4.567  1.00 70.59  ? 101 ASP D OD1 1 
ATOM   2879 O  OD2 . ASP C 1 101 ? -12.906 -11.279 -6.587  1.00 64.42  ? 101 ASP D OD2 1 
ATOM   2880 N  N   . SER C 1 102 ? -10.344 -9.520  -5.183  1.00 58.83  ? 102 SER D N   1 
ATOM   2881 C  CA  . SER C 1 102 ? -9.096  -9.518  -5.955  1.00 60.76  ? 102 SER D CA  1 
ATOM   2882 C  C   . SER C 1 102 ? -9.008  -10.609 -7.041  1.00 64.96  ? 102 SER D C   1 
ATOM   2883 O  O   . SER C 1 102 ? -7.998  -10.670 -7.759  1.00 67.43  ? 102 SER D O   1 
ATOM   2884 C  CB  . SER C 1 102 ? -7.900  -9.590  -5.010  1.00 67.85  ? 102 SER D CB  1 
ATOM   2885 O  OG  . SER C 1 102 ? -7.846  -8.417  -4.218  1.00 77.94  ? 102 SER D OG  1 
ATOM   2886 N  N   . VAL C 1 103 ? -10.071 -11.438 -7.196  1.00 58.93  ? 103 VAL D N   1 
ATOM   2887 C  CA  . VAL C 1 103 ? -10.122 -12.508 -8.209  1.00 58.55  ? 103 VAL D CA  1 
ATOM   2888 C  C   . VAL C 1 103 ? -10.902 -12.032 -9.457  1.00 60.94  ? 103 VAL D C   1 
ATOM   2889 O  O   . VAL C 1 103 ? -10.462 -12.295 -10.581 1.00 61.35  ? 103 VAL D O   1 
ATOM   2890 C  CB  . VAL C 1 103 ? -10.617 -13.869 -7.637  1.00 62.83  ? 103 VAL D CB  1 
ATOM   2891 C  CG1 . VAL C 1 103 ? -10.691 -14.939 -8.724  1.00 63.08  ? 103 VAL D CG1 1 
ATOM   2892 C  CG2 . VAL C 1 103 ? -9.705  -14.345 -6.508  1.00 65.34  ? 103 VAL D CG2 1 
ATOM   2893 N  N   . ILE C 1 104 ? -12.029 -11.307 -9.259  1.00 54.18  ? 104 ILE D N   1 
ATOM   2894 C  CA  . ILE C 1 104 ? -12.805 -10.741 -10.378 1.00 52.23  ? 104 ILE D CA  1 
ATOM   2895 C  C   . ILE C 1 104 ? -12.056 -9.546  -10.964 1.00 55.75  ? 104 ILE D C   1 
ATOM   2896 O  O   . ILE C 1 104 ? -11.210 -8.945  -10.285 1.00 55.81  ? 104 ILE D O   1 
ATOM   2897 C  CB  . ILE C 1 104 ? -14.286 -10.384 -10.046 1.00 53.18  ? 104 ILE D CB  1 
ATOM   2898 C  CG1 . ILE C 1 104 ? -14.409 -9.365  -8.878  1.00 53.99  ? 104 ILE D CG1 1 
ATOM   2899 C  CG2 . ILE C 1 104 ? -15.116 -11.639 -9.806  1.00 53.33  ? 104 ILE D CG2 1 
ATOM   2900 C  CD1 . ILE C 1 104 ? -15.767 -8.556  -8.808  1.00 51.97  ? 104 ILE D CD1 1 
ATOM   2901 N  N   . SER C 1 105 ? -12.367 -9.208  -12.223 1.00 49.70  ? 105 SER D N   1 
ATOM   2902 C  CA  . SER C 1 105 ? -11.762 -8.074  -12.901 1.00 50.12  ? 105 SER D CA  1 
ATOM   2903 C  C   . SER C 1 105 ? -12.747 -7.451  -13.889 1.00 54.54  ? 105 SER D C   1 
ATOM   2904 O  O   . SER C 1 105 ? -13.776 -8.054  -14.202 1.00 51.52  ? 105 SER D O   1 
ATOM   2905 C  CB  . SER C 1 105 ? -10.480 -8.507  -13.608 1.00 54.73  ? 105 SER D CB  1 
ATOM   2906 O  OG  . SER C 1 105 ? -9.742  -7.374  -14.031 1.00 61.32  ? 105 SER D OG  1 
ATOM   2907 N  N   . LEU C 1 106 ? -12.445 -6.230  -14.351 1.00 54.27  ? 106 LEU D N   1 
ATOM   2908 C  CA  . LEU C 1 106 ? -13.253 -5.529  -15.351 1.00 53.69  ? 106 LEU D CA  1 
ATOM   2909 C  C   . LEU C 1 106 ? -12.490 -5.497  -16.692 1.00 59.45  ? 106 LEU D C   1 
ATOM   2910 O  O   . LEU C 1 106 ? -12.807 -4.698  -17.574 1.00 59.82  ? 106 LEU D O   1 
ATOM   2911 C  CB  . LEU C 1 106 ? -13.669 -4.114  -14.871 1.00 54.00  ? 106 LEU D CB  1 
ATOM   2912 C  CG  . LEU C 1 106 ? -14.460 -4.000  -13.550 1.00 56.75  ? 106 LEU D CG  1 
ATOM   2913 C  CD1 . LEU C 1 106 ? -14.766 -2.559  -13.239 1.00 57.87  ? 106 LEU D CD1 1 
ATOM   2914 C  CD2 . LEU C 1 106 ? -15.766 -4.792  -13.589 1.00 55.21  ? 106 LEU D CD2 1 
ATOM   2915 N  N   . SER C 1 107 ? -11.491 -6.405  -16.835 1.00 56.97  ? 107 SER D N   1 
ATOM   2916 C  CA  . SER C 1 107 ? -10.633 -6.615  -18.010 1.00 58.70  ? 107 SER D CA  1 
ATOM   2917 C  C   . SER C 1 107 ? -9.955  -7.995  -17.916 1.00 62.81  ? 107 SER D C   1 
ATOM   2918 O  O   . SER C 1 107 ? -10.018 -8.641  -16.873 1.00 61.18  ? 107 SER D O   1 
ATOM   2919 C  CB  . SER C 1 107 ? -9.565  -5.523  -18.101 1.00 65.34  ? 107 SER D CB  1 
ATOM   2920 O  OG  . SER C 1 107 ? -8.674  -5.563  -16.997 1.00 75.82  ? 107 SER D OG  1 
ATOM   2921 N  N   . GLY C 1 108 ? -9.307  -8.418  -18.997 1.00 61.69  ? 108 GLY D N   1 
ATOM   2922 C  CA  . GLY C 1 108 ? -8.544  -9.664  -19.055 1.00 62.87  ? 108 GLY D CA  1 
ATOM   2923 C  C   . GLY C 1 108 ? -9.359  -10.939 -19.018 1.00 63.93  ? 108 GLY D C   1 
ATOM   2924 O  O   . GLY C 1 108 ? -10.555 -10.921 -19.302 1.00 60.20  ? 108 GLY D O   1 
ATOM   2925 N  N   . ASP C 1 109 ? -8.693  -12.062 -18.679 1.00 62.27  ? 109 ASP D N   1 
ATOM   2926 C  CA  . ASP C 1 109 ? -9.274  -13.410 -18.605 1.00 61.61  ? 109 ASP D CA  1 
ATOM   2927 C  C   . ASP C 1 109 ? -10.362 -13.575 -17.527 1.00 61.52  ? 109 ASP D C   1 
ATOM   2928 O  O   . ASP C 1 109 ? -11.200 -14.470 -17.645 1.00 60.27  ? 109 ASP D O   1 
ATOM   2929 C  CB  . ASP C 1 109 ? -8.163  -14.469 -18.413 1.00 66.52  ? 109 ASP D CB  1 
ATOM   2930 C  CG  . ASP C 1 109 ? -7.119  -14.549 -19.527 1.00 80.75  ? 109 ASP D CG  1 
ATOM   2931 O  OD1 . ASP C 1 109 ? -7.437  -14.162 -20.675 1.00 82.78  ? 109 ASP D OD1 1 
ATOM   2932 O  OD2 . ASP C 1 109 ? -5.991  -15.019 -19.252 1.00 85.95  ? 109 ASP D OD2 1 
ATOM   2933 N  N   . HIS C 1 110 ? -10.340 -12.730 -16.481 1.00 56.61  ? 110 HIS D N   1 
ATOM   2934 C  CA  . HIS C 1 110 ? -11.296 -12.779 -15.373 1.00 54.19  ? 110 HIS D CA  1 
ATOM   2935 C  C   . HIS C 1 110 ? -12.389 -11.705 -15.494 1.00 55.27  ? 110 HIS D C   1 
ATOM   2936 O  O   . HIS C 1 110 ? -13.152 -11.508 -14.546 1.00 53.16  ? 110 HIS D O   1 
ATOM   2937 C  CB  . HIS C 1 110 ? -10.553 -12.682 -14.024 1.00 56.04  ? 110 HIS D CB  1 
ATOM   2938 C  CG  . HIS C 1 110 ? -9.677  -13.860 -13.701 1.00 61.70  ? 110 HIS D CG  1 
ATOM   2939 N  ND1 . HIS C 1 110 ? -9.335  -14.160 -12.394 1.00 64.17  ? 110 HIS D ND1 1 
ATOM   2940 C  CD2 . HIS C 1 110 ? -9.098  -14.772 -14.521 1.00 65.47  ? 110 HIS D CD2 1 
ATOM   2941 C  CE1 . HIS C 1 110 ? -8.570  -15.237 -12.459 1.00 65.79  ? 110 HIS D CE1 1 
ATOM   2942 N  NE2 . HIS C 1 110 ? -8.393  -15.637 -13.719 1.00 67.23  ? 110 HIS D NE2 1 
ATOM   2943 N  N   . CYS C 1 111 ? -12.499 -11.049 -16.676 1.00 51.07  ? 111 CYS D N   1 
ATOM   2944 C  CA  . CYS C 1 111 ? -13.490 -10.003 -16.930 1.00 49.28  ? 111 CYS D CA  1 
ATOM   2945 C  C   . CYS C 1 111 ? -14.919 -10.495 -16.750 1.00 49.35  ? 111 CYS D C   1 
ATOM   2946 O  O   . CYS C 1 111 ? -15.284 -11.542 -17.290 1.00 48.76  ? 111 CYS D O   1 
ATOM   2947 C  CB  . CYS C 1 111 ? -13.284 -9.348  -18.290 1.00 51.34  ? 111 CYS D CB  1 
ATOM   2948 S  SG  . CYS C 1 111 ? -14.332 -7.897  -18.566 1.00 54.39  ? 111 CYS D SG  1 
ATOM   2949 N  N   . ILE C 1 112 ? -15.710 -9.752  -15.952 1.00 44.73  ? 112 ILE D N   1 
ATOM   2950 C  CA  . ILE C 1 112 ? -17.092 -10.110 -15.611 1.00 42.89  ? 112 ILE D CA  1 
ATOM   2951 C  C   . ILE C 1 112 ? -18.135 -9.239  -16.343 1.00 45.78  ? 112 ILE D C   1 
ATOM   2952 O  O   . ILE C 1 112 ? -19.338 -9.471  -16.192 1.00 42.81  ? 112 ILE D O   1 
ATOM   2953 C  CB  . ILE C 1 112 ? -17.300 -10.136 -14.078 1.00 45.36  ? 112 ILE D CB  1 
ATOM   2954 C  CG1 . ILE C 1 112 ? -17.105 -8.724  -13.454 1.00 46.40  ? 112 ILE D CG1 1 
ATOM   2955 C  CG2 . ILE C 1 112 ? -16.397 -11.216 -13.427 1.00 44.63  ? 112 ILE D CG2 1 
ATOM   2956 C  CD1 . ILE C 1 112 ? -17.694 -8.520  -12.093 1.00 46.69  ? 112 ILE D CD1 1 
ATOM   2957 N  N   . ILE C 1 113 ? -17.672 -8.263  -17.148 1.00 44.84  ? 113 ILE D N   1 
ATOM   2958 C  CA  . ILE C 1 113 ? -18.549 -7.408  -17.970 1.00 44.68  ? 113 ILE D CA  1 
ATOM   2959 C  C   . ILE C 1 113 ? -19.226 -8.280  -19.033 1.00 46.71  ? 113 ILE D C   1 
ATOM   2960 O  O   . ILE C 1 113 ? -18.552 -9.064  -19.706 1.00 45.45  ? 113 ILE D O   1 
ATOM   2961 C  CB  . ILE C 1 113 ? -17.764 -6.197  -18.570 1.00 48.99  ? 113 ILE D CB  1 
ATOM   2962 C  CG1 . ILE C 1 113 ? -17.335 -5.220  -17.435 1.00 49.66  ? 113 ILE D CG1 1 
ATOM   2963 C  CG2 . ILE C 1 113 ? -18.593 -5.457  -19.647 1.00 50.10  ? 113 ILE D CG2 1 
ATOM   2964 C  CD1 . ILE C 1 113 ? -16.195 -4.266  -17.775 1.00 58.26  ? 113 ILE D CD1 1 
ATOM   2965 N  N   . GLY C 1 114 ? -20.556 -8.159  -19.143 1.00 42.70  ? 114 GLY D N   1 
ATOM   2966 C  CA  . GLY C 1 114 ? -21.345 -8.937  -20.096 1.00 41.59  ? 114 GLY D CA  1 
ATOM   2967 C  C   . GLY C 1 114 ? -21.792 -10.269 -19.527 1.00 44.43  ? 114 GLY D C   1 
ATOM   2968 O  O   . GLY C 1 114 ? -22.404 -11.067 -20.226 1.00 44.15  ? 114 GLY D O   1 
ATOM   2969 N  N   . ARG C 1 115 ? -21.459 -10.537 -18.259 1.00 41.84  ? 115 ARG D N   1 
ATOM   2970 C  CA  . ARG C 1 115 ? -21.858 -11.761 -17.558 1.00 42.02  ? 115 ARG D CA  1 
ATOM   2971 C  C   . ARG C 1 115 ? -23.016 -11.394 -16.622 1.00 45.54  ? 115 ARG D C   1 
ATOM   2972 O  O   . ARG C 1 115 ? -23.444 -10.236 -16.634 1.00 44.76  ? 115 ARG D O   1 
ATOM   2973 C  CB  . ARG C 1 115 ? -20.657 -12.396 -16.829 1.00 42.87  ? 115 ARG D CB  1 
ATOM   2974 C  CG  . ARG C 1 115 ? -19.443 -12.488 -17.750 1.00 46.20  ? 115 ARG D CG  1 
ATOM   2975 C  CD  . ARG C 1 115 ? -18.544 -13.657 -17.478 1.00 47.13  ? 115 ARG D CD  1 
ATOM   2976 N  NE  . ARG C 1 115 ? -17.450 -13.675 -18.451 1.00 52.78  ? 115 ARG D NE  1 
ATOM   2977 C  CZ  . ARG C 1 115 ? -17.357 -14.525 -19.467 1.00 60.12  ? 115 ARG D CZ  1 
ATOM   2978 N  NH1 . ARG C 1 115 ? -18.271 -15.469 -19.637 1.00 44.17  ? 115 ARG D NH1 1 
ATOM   2979 N  NH2 . ARG C 1 115 ? -16.329 -14.461 -20.298 1.00 57.93  ? 115 ARG D NH2 1 
ATOM   2980 N  N   . THR C 1 116 ? -23.567 -12.361 -15.865 1.00 42.43  ? 116 THR D N   1 
ATOM   2981 C  CA  . THR C 1 116 ? -24.720 -12.085 -15.008 1.00 41.69  ? 116 THR D CA  1 
ATOM   2982 C  C   . THR C 1 116 ? -24.399 -12.173 -13.525 1.00 44.99  ? 116 THR D C   1 
ATOM   2983 O  O   . THR C 1 116 ? -23.845 -13.164 -13.076 1.00 44.33  ? 116 THR D O   1 
ATOM   2984 C  CB  . THR C 1 116 ? -25.920 -12.990 -15.390 1.00 44.13  ? 116 THR D CB  1 
ATOM   2985 O  OG1 . THR C 1 116 ? -26.326 -12.709 -16.722 1.00 44.06  ? 116 THR D OG1 1 
ATOM   2986 C  CG2 . THR C 1 116 ? -27.127 -12.801 -14.496 1.00 43.34  ? 116 THR D CG2 1 
ATOM   2987 N  N   . LEU C 1 117 ? -24.810 -11.156 -12.764 1.00 42.62  ? 117 LEU D N   1 
ATOM   2988 C  CA  . LEU C 1 117 ? -24.696 -11.157 -11.318 1.00 42.89  ? 117 LEU D CA  1 
ATOM   2989 C  C   . LEU C 1 117 ? -26.006 -11.733 -10.785 1.00 46.62  ? 117 LEU D C   1 
ATOM   2990 O  O   . LEU C 1 117 ? -27.080 -11.317 -11.224 1.00 45.79  ? 117 LEU D O   1 
ATOM   2991 C  CB  . LEU C 1 117 ? -24.457 -9.742  -10.782 1.00 43.10  ? 117 LEU D CB  1 
ATOM   2992 C  CG  . LEU C 1 117 ? -24.307 -9.621  -9.248  1.00 47.24  ? 117 LEU D CG  1 
ATOM   2993 C  CD1 . LEU C 1 117 ? -23.054 -10.325 -8.759  1.00 47.50  ? 117 LEU D CD1 1 
ATOM   2994 C  CD2 . LEU C 1 117 ? -24.289 -8.194  -8.840  1.00 47.70  ? 117 LEU D CD2 1 
ATOM   2995 N  N   . VAL C 1 118 ? -25.921 -12.728 -9.892  1.00 43.76  ? 118 VAL D N   1 
ATOM   2996 C  CA  . VAL C 1 118 ? -27.097 -13.400 -9.327  1.00 44.97  ? 118 VAL D CA  1 
ATOM   2997 C  C   . VAL C 1 118 ? -27.078 -13.394 -7.795  1.00 49.39  ? 118 VAL D C   1 
ATOM   2998 O  O   . VAL C 1 118 ? -26.052 -13.694 -7.192  1.00 47.25  ? 118 VAL D O   1 
ATOM   2999 C  CB  . VAL C 1 118 ? -27.271 -14.858 -9.875  1.00 49.24  ? 118 VAL D CB  1 
ATOM   3000 C  CG1 . VAL C 1 118 ? -28.485 -15.559 -9.259  1.00 50.46  ? 118 VAL D CG1 1 
ATOM   3001 C  CG2 . VAL C 1 118 ? -27.361 -14.891 -11.402 1.00 47.87  ? 118 VAL D CG2 1 
ATOM   3002 N  N   . VAL C 1 119 ? -28.240 -13.100 -7.187  1.00 49.02  ? 119 VAL D N   1 
ATOM   3003 C  CA  . VAL C 1 119 ? -28.495 -13.186 -5.747  1.00 50.37  ? 119 VAL D CA  1 
ATOM   3004 C  C   . VAL C 1 119 ? -29.365 -14.447 -5.542  1.00 55.21  ? 119 VAL D C   1 
ATOM   3005 O  O   . VAL C 1 119 ? -30.409 -14.589 -6.184  1.00 54.32  ? 119 VAL D O   1 
ATOM   3006 C  CB  . VAL C 1 119 ? -29.045 -11.882 -5.096  1.00 55.20  ? 119 VAL D CB  1 
ATOM   3007 C  CG1 . VAL C 1 119 ? -30.322 -11.387 -5.765  1.00 55.51  ? 119 VAL D CG1 1 
ATOM   3008 C  CG2 . VAL C 1 119 ? -29.243 -12.042 -3.588  1.00 57.34  ? 119 VAL D CG2 1 
ATOM   3009 N  N   . HIS C 1 120 ? -28.875 -15.398 -4.728  1.00 53.11  ? 120 HIS D N   1 
ATOM   3010 C  CA  . HIS C 1 120 ? -29.526 -16.693 -4.511  1.00 55.28  ? 120 HIS D CA  1 
ATOM   3011 C  C   . HIS C 1 120 ? -30.444 -16.737 -3.311  1.00 62.66  ? 120 HIS D C   1 
ATOM   3012 O  O   . HIS C 1 120 ? -30.335 -15.898 -2.418  1.00 62.36  ? 120 HIS D O   1 
ATOM   3013 C  CB  . HIS C 1 120 ? -28.478 -17.815 -4.434  1.00 56.22  ? 120 HIS D CB  1 
ATOM   3014 C  CG  . HIS C 1 120 ? -27.801 -18.088 -5.744  1.00 57.54  ? 120 HIS D CG  1 
ATOM   3015 N  ND1 . HIS C 1 120 ? -28.169 -19.159 -6.536  1.00 60.38  ? 120 HIS D ND1 1 
ATOM   3016 C  CD2 . HIS C 1 120 ? -26.815 -17.404 -6.367  1.00 56.37  ? 120 HIS D CD2 1 
ATOM   3017 C  CE1 . HIS C 1 120 ? -27.388 -19.104 -7.604  1.00 57.64  ? 120 HIS D CE1 1 
ATOM   3018 N  NE2 . HIS C 1 120 ? -26.562 -18.061 -7.551  1.00 55.70  ? 120 HIS D NE2 1 
ATOM   3019 N  N   . GLU C 1 121 ? -31.345 -17.735 -3.289  1.00 63.08  ? 121 GLU D N   1 
ATOM   3020 C  CA  . GLU C 1 121 ? -32.296 -17.964 -2.202  1.00 66.77  ? 121 GLU D CA  1 
ATOM   3021 C  C   . GLU C 1 121 ? -31.559 -18.405 -0.940  1.00 72.60  ? 121 GLU D C   1 
ATOM   3022 O  O   . GLU C 1 121 ? -31.749 -17.801 0.117   1.00 73.65  ? 121 GLU D O   1 
ATOM   3023 C  CB  . GLU C 1 121 ? -33.354 -19.001 -2.625  1.00 70.96  ? 121 GLU D CB  1 
ATOM   3024 C  CG  . GLU C 1 121 ? -34.461 -19.229 -1.606  1.00 84.59  ? 121 GLU D CG  1 
ATOM   3025 C  CD  . GLU C 1 121 ? -35.248 -20.521 -1.747  1.00 106.02 ? 121 GLU D CD  1 
ATOM   3026 O  OE1 . GLU C 1 121 ? -36.113 -20.774 -0.878  1.00 103.31 ? 121 GLU D OE1 1 
ATOM   3027 O  OE2 . GLU C 1 121 ? -35.003 -21.280 -2.714  1.00 95.08  ? 121 GLU D OE2 1 
ATOM   3028 N  N   . LYS C 1 122 ? -30.711 -19.444 -1.053  1.00 69.78  ? 122 LYS D N   1 
ATOM   3029 C  CA  . LYS C 1 122 ? -29.958 -19.982 0.082   1.00 71.35  ? 122 LYS D CA  1 
ATOM   3030 C  C   . LYS C 1 122 ? -28.537 -19.438 0.182   1.00 72.81  ? 122 LYS D C   1 
ATOM   3031 O  O   . LYS C 1 122 ? -27.995 -18.896 -0.785  1.00 68.79  ? 122 LYS D O   1 
ATOM   3032 C  CB  . LYS C 1 122 ? -29.963 -21.523 0.077   1.00 76.69  ? 122 LYS D CB  1 
ATOM   3033 C  CG  . LYS C 1 122 ? -31.273 -22.141 0.574   1.00 94.26  ? 122 LYS D CG  1 
ATOM   3034 C  CD  . LYS C 1 122 ? -32.059 -22.840 -0.540  1.00 104.91 ? 122 LYS D CD  1 
ATOM   3035 C  CE  . LYS C 1 122 ? -31.762 -24.321 -0.665  1.00 116.37 ? 122 LYS D CE  1 
ATOM   3036 N  NZ  . LYS C 1 122 ? -32.376 -25.114 0.436   1.00 128.34 ? 122 LYS D NZ  1 
ATOM   3037 N  N   . ALA C 1 123 ? -27.947 -19.580 1.378   1.00 71.65  ? 123 ALA D N   1 
ATOM   3038 C  CA  . ALA C 1 123 ? -26.589 -19.161 1.705   1.00 70.30  ? 123 ALA D CA  1 
ATOM   3039 C  C   . ALA C 1 123 ? -25.564 -20.080 1.039   1.00 74.53  ? 123 ALA D C   1 
ATOM   3040 O  O   . ALA C 1 123 ? -25.812 -21.279 0.872   1.00 76.44  ? 123 ALA D O   1 
ATOM   3041 C  CB  . ALA C 1 123 ? -26.398 -19.169 3.216   1.00 73.59  ? 123 ALA D CB  1 
ATOM   3042 N  N   . ASP C 1 124 ? -24.417 -19.499 0.653   1.00 68.47  ? 124 ASP D N   1 
ATOM   3043 C  CA  . ASP C 1 124 ? -23.287 -20.170 0.015   1.00 92.59  ? 124 ASP D CA  1 
ATOM   3044 C  C   . ASP C 1 124 ? -22.286 -20.651 1.073   1.00 107.85 ? 124 ASP D C   1 
ATOM   3045 O  O   . ASP C 1 124 ? -22.571 -20.624 2.273   1.00 64.39  ? 124 ASP D O   1 
ATOM   3046 C  CB  . ASP C 1 124 ? -22.613 -19.202 -0.981  1.00 91.34  ? 124 ASP D CB  1 
ATOM   3047 C  CG  . ASP C 1 124 ? -21.437 -19.756 -1.769  1.00 104.06 ? 124 ASP D CG  1 
ATOM   3048 O  OD1 . ASP C 1 124 ? -21.541 -20.898 -2.274  1.00 107.21 ? 124 ASP D OD1 1 
ATOM   3049 O  OD2 . ASP C 1 124 ? -20.425 -19.036 -1.908  1.00 108.15 ? 124 ASP D OD2 1 
ATOM   3050 N  N   . GLY C 1 141 ? -30.087 -22.569 -3.734  1.00 81.33  ? 141 GLY D N   1 
ATOM   3051 C  CA  . GLY C 1 141 ? -31.343 -23.086 -4.265  1.00 83.31  ? 141 GLY D CA  1 
ATOM   3052 C  C   . GLY C 1 141 ? -31.820 -22.333 -5.492  1.00 83.74  ? 141 GLY D C   1 
ATOM   3053 O  O   . GLY C 1 141 ? -31.170 -22.383 -6.541  1.00 82.78  ? 141 GLY D O   1 
ATOM   3054 N  N   . SER C 1 142 ? -32.955 -21.622 -5.370  1.00 78.23  ? 142 SER D N   1 
ATOM   3055 C  CA  . SER C 1 142 ? -33.520 -20.830 -6.469  1.00 75.25  ? 142 SER D CA  1 
ATOM   3056 C  C   . SER C 1 142 ? -32.739 -19.527 -6.700  1.00 72.15  ? 142 SER D C   1 
ATOM   3057 O  O   . SER C 1 142 ? -32.089 -19.028 -5.781  1.00 70.09  ? 142 SER D O   1 
ATOM   3058 C  CB  . SER C 1 142 ? -34.993 -20.527 -6.212  1.00 80.57  ? 142 SER D CB  1 
ATOM   3059 O  OG  . SER C 1 142 ? -35.743 -21.728 -6.136  1.00 93.93  ? 142 SER D OG  1 
ATOM   3060 N  N   . ARG C 1 143 ? -32.798 -18.983 -7.928  1.00 65.19  ? 143 ARG D N   1 
ATOM   3061 C  CA  . ARG C 1 143 ? -32.127 -17.726 -8.261  1.00 61.33  ? 143 ARG D CA  1 
ATOM   3062 C  C   . ARG C 1 143 ? -33.150 -16.601 -8.121  1.00 65.31  ? 143 ARG D C   1 
ATOM   3063 O  O   . ARG C 1 143 ? -34.101 -16.523 -8.907  1.00 65.99  ? 143 ARG D O   1 
ATOM   3064 C  CB  . ARG C 1 143 ? -31.495 -17.787 -9.657  1.00 59.58  ? 143 ARG D CB  1 
ATOM   3065 C  CG  . ARG C 1 143 ? -30.393 -18.829 -9.759  1.00 63.13  ? 143 ARG D CG  1 
ATOM   3066 C  CD  . ARG C 1 143 ? -29.914 -18.971 -11.177 1.00 65.05  ? 143 ARG D CD  1 
ATOM   3067 N  NE  . ARG C 1 143 ? -29.009 -20.108 -11.323 1.00 63.08  ? 143 ARG D NE  1 
ATOM   3068 C  CZ  . ARG C 1 143 ? -28.251 -20.325 -12.390 1.00 70.50  ? 143 ARG D CZ  1 
ATOM   3069 N  NH1 . ARG C 1 143 ? -28.272 -19.476 -13.411 1.00 51.20  ? 143 ARG D NH1 1 
ATOM   3070 N  NH2 . ARG C 1 143 ? -27.457 -21.386 -12.444 1.00 58.77  ? 143 ARG D NH2 1 
ATOM   3071 N  N   . LEU C 1 144 ? -32.995 -15.783 -7.058  1.00 61.23  ? 144 LEU D N   1 
ATOM   3072 C  CA  . LEU C 1 144 ? -33.926 -14.713 -6.681  1.00 61.84  ? 144 LEU D CA  1 
ATOM   3073 C  C   . LEU C 1 144 ? -33.993 -13.571 -7.683  1.00 62.18  ? 144 LEU D C   1 
ATOM   3074 O  O   . LEU C 1 144 ? -35.084 -13.236 -8.149  1.00 62.36  ? 144 LEU D O   1 
ATOM   3075 C  CB  . LEU C 1 144 ? -33.638 -14.187 -5.257  1.00 62.55  ? 144 LEU D CB  1 
ATOM   3076 C  CG  . LEU C 1 144 ? -33.964 -15.132 -4.097  1.00 70.70  ? 144 LEU D CG  1 
ATOM   3077 C  CD1 . LEU C 1 144 ? -33.576 -14.512 -2.771  1.00 71.53  ? 144 LEU D CD1 1 
ATOM   3078 C  CD2 . LEU C 1 144 ? -35.450 -15.502 -4.063  1.00 77.18  ? 144 LEU D CD2 1 
ATOM   3079 N  N   . ALA C 1 145 ? -32.835 -12.970 -8.014  1.00 54.95  ? 145 ALA D N   1 
ATOM   3080 C  CA  . ALA C 1 145 ? -32.754 -11.883 -8.987  1.00 52.48  ? 145 ALA D CA  1 
ATOM   3081 C  C   . ALA C 1 145 ? -31.408 -11.909 -9.681  1.00 54.25  ? 145 ALA D C   1 
ATOM   3082 O  O   . ALA C 1 145 ? -30.437 -12.470 -9.163  1.00 53.06  ? 145 ALA D O   1 
ATOM   3083 C  CB  . ALA C 1 145 ? -32.968 -10.533 -8.317  1.00 53.47  ? 145 ALA D CB  1 
ATOM   3084 N  N   . CYS C 1 146 ? -31.366 -11.319 -10.866 1.00 50.32  ? 146 CYS D N   1 
ATOM   3085 C  CA  . CYS C 1 146 ? -30.158 -11.250 -11.670 1.00 48.64  ? 146 CYS D CA  1 
ATOM   3086 C  C   . CYS C 1 146 ? -30.154 -10.040 -12.562 1.00 49.23  ? 146 CYS D C   1 
ATOM   3087 O  O   . CYS C 1 146 ? -31.191 -9.399  -12.769 1.00 47.57  ? 146 CYS D O   1 
ATOM   3088 C  CB  . CYS C 1 146 ? -29.945 -12.540 -12.459 1.00 50.28  ? 146 CYS D CB  1 
ATOM   3089 S  SG  . CYS C 1 146 ? -31.321 -12.997 -13.540 1.00 57.15  ? 146 CYS D SG  1 
ATOM   3090 N  N   . GLY C 1 147 ? -28.976 -9.729  -13.074 1.00 45.99  ? 147 GLY D N   1 
ATOM   3091 C  CA  . GLY C 1 147 ? -28.787 -8.662  -14.048 1.00 44.92  ? 147 GLY D CA  1 
ATOM   3092 C  C   . GLY C 1 147 ? -27.517 -8.855  -14.839 1.00 45.27  ? 147 GLY D C   1 
ATOM   3093 O  O   . GLY C 1 147 ? -26.562 -9.468  -14.339 1.00 44.74  ? 147 GLY D O   1 
ATOM   3094 N  N   . VAL C 1 148 ? -27.476 -8.295  -16.062 1.00 39.96  ? 148 VAL D N   1 
ATOM   3095 C  CA  . VAL C 1 148 ? -26.269 -8.350  -16.895 1.00 39.38  ? 148 VAL D CA  1 
ATOM   3096 C  C   . VAL C 1 148 ? -25.334 -7.229  -16.411 1.00 43.22  ? 148 VAL D C   1 
ATOM   3097 O  O   . VAL C 1 148 ? -25.782 -6.100  -16.210 1.00 43.99  ? 148 VAL D O   1 
ATOM   3098 C  CB  . VAL C 1 148 ? -26.575 -8.245  -18.422 1.00 43.13  ? 148 VAL D CB  1 
ATOM   3099 C  CG1 . VAL C 1 148 ? -25.292 -8.369  -19.257 1.00 42.80  ? 148 VAL D CG1 1 
ATOM   3100 C  CG2 . VAL C 1 148 ? -27.607 -9.287  -18.864 1.00 43.52  ? 148 VAL D CG2 1 
ATOM   3101 N  N   . ILE C 1 149 ? -24.048 -7.537  -16.215 1.00 39.99  ? 149 ILE D N   1 
ATOM   3102 C  CA  . ILE C 1 149 ? -23.092 -6.534  -15.767 1.00 39.85  ? 149 ILE D CA  1 
ATOM   3103 C  C   . ILE C 1 149 ? -22.687 -5.681  -16.966 1.00 43.34  ? 149 ILE D C   1 
ATOM   3104 O  O   . ILE C 1 149 ? -22.091 -6.191  -17.910 1.00 43.42  ? 149 ILE D O   1 
ATOM   3105 C  CB  . ILE C 1 149 ? -21.884 -7.173  -15.027 1.00 42.66  ? 149 ILE D CB  1 
ATOM   3106 C  CG1 . ILE C 1 149 ? -22.357 -7.946  -13.757 1.00 42.17  ? 149 ILE D CG1 1 
ATOM   3107 C  CG2 . ILE C 1 149 ? -20.856 -6.097  -14.653 1.00 44.42  ? 149 ILE D CG2 1 
ATOM   3108 C  CD1 . ILE C 1 149 ? -21.557 -9.216  -13.440 1.00 47.74  ? 149 ILE D CD1 1 
ATOM   3109 N  N   . GLY C 1 150 ? -23.020 -4.400  -16.919 1.00 40.03  ? 150 GLY D N   1 
ATOM   3110 C  CA  . GLY C 1 150 ? -22.716 -3.484  -18.015 1.00 41.42  ? 150 GLY D CA  1 
ATOM   3111 C  C   . GLY C 1 150 ? -21.731 -2.390  -17.666 1.00 47.71  ? 150 GLY D C   1 
ATOM   3112 O  O   . GLY C 1 150 ? -21.551 -2.059  -16.493 1.00 46.14  ? 150 GLY D O   1 
ATOM   3113 N  N   . ILE C 1 151 ? -21.102 -1.810  -18.699 1.00 46.68  ? 151 ILE D N   1 
ATOM   3114 C  CA  . ILE C 1 151 ? -20.129 -0.721  -18.585 1.00 47.80  ? 151 ILE D CA  1 
ATOM   3115 C  C   . ILE C 1 151 ? -20.841 0.536   -18.068 1.00 53.33  ? 151 ILE D C   1 
ATOM   3116 O  O   . ILE C 1 151 ? -21.825 0.965   -18.664 1.00 52.83  ? 151 ILE D O   1 
ATOM   3117 C  CB  . ILE C 1 151 ? -19.418 -0.473  -19.946 1.00 51.56  ? 151 ILE D CB  1 
ATOM   3118 C  CG1 . ILE C 1 151 ? -18.657 -1.738  -20.408 1.00 50.71  ? 151 ILE D CG1 1 
ATOM   3119 C  CG2 . ILE C 1 151 ? -18.486 0.758   -19.879 1.00 54.85  ? 151 ILE D CG2 1 
ATOM   3120 C  CD1 . ILE C 1 151 ? -18.323 -1.814  -21.908 1.00 57.03  ? 151 ILE D CD1 1 
ATOM   3121 N  N   . ALA C 1 152 ? -20.345 1.106   -16.955 1.00 51.24  ? 152 ALA D N   1 
ATOM   3122 C  CA  . ALA C 1 152 ? -20.919 2.309   -16.354 1.00 53.10  ? 152 ALA D CA  1 
ATOM   3123 C  C   . ALA C 1 152 ? -20.055 3.542   -16.638 1.00 60.76  ? 152 ALA D C   1 
ATOM   3124 O  O   . ALA C 1 152 ? -18.874 3.411   -16.977 1.00 60.42  ? 152 ALA D O   1 
ATOM   3125 C  CB  . ALA C 1 152 ? -21.084 2.114   -14.852 1.00 53.44  ? 152 ALA D CB  1 
ATOM   3126 N  N   . GLN C 1 153 ? -20.659 4.739   -16.506 1.00 61.00  ? 153 GLN D N   1 
ATOM   3127 C  CA  . GLN C 1 153 ? -20.023 6.041   -16.722 1.00 68.31  ? 153 GLN D CA  1 
ATOM   3128 C  C   . GLN C 1 153 ? -18.955 6.343   -15.653 1.00 86.27  ? 153 GLN D C   1 
ATOM   3129 O  O   . GLN C 1 153 ? -19.226 6.143   -14.445 1.00 86.94  ? 153 GLN D O   1 
ATOM   3130 C  CB  . GLN C 1 153 ? -21.099 7.139   -16.755 1.00 72.00  ? 153 GLN D CB  1 
ATOM   3131 C  CG  . GLN C 1 153 ? -20.626 8.494   -17.284 1.00 89.58  ? 153 GLN D CG  1 
ATOM   3132 C  CD  . GLN C 1 153 ? -21.772 9.371   -17.738 1.00 107.61 ? 153 GLN D CD  1 
ATOM   3133 O  OE1 . GLN C 1 153 ? -22.899 9.302   -17.226 1.00 99.65  ? 153 GLN D OE1 1 
ATOM   3134 N  NE2 . GLN C 1 153 ? -21.503 10.238  -18.704 1.00 104.00 ? 153 GLN D NE2 1 
ATOM   3135 O  OXT . GLN C 1 153 ? -17.848 6.783   -16.033 1.00 108.65 ? 153 GLN D OXT 1 
ATOM   3136 N  N   . ALA D 1 1   ? -16.597 -18.952 -33.036 1.00 81.04  ? 1   ALA F N   1 
ATOM   3137 C  CA  . ALA D 1 1   ? -17.692 -18.000 -33.215 1.00 77.91  ? 1   ALA F CA  1 
ATOM   3138 C  C   . ALA D 1 1   ? -18.205 -17.449 -31.879 1.00 79.14  ? 1   ALA F C   1 
ATOM   3139 O  O   . ALA D 1 1   ? -18.757 -18.196 -31.063 1.00 79.96  ? 1   ALA F O   1 
ATOM   3140 C  CB  . ALA D 1 1   ? -18.829 -18.643 -33.997 1.00 79.74  ? 1   ALA F CB  1 
ATOM   3141 N  N   . THR D 1 2   ? -18.014 -16.136 -31.658 1.00 71.49  ? 2   THR F N   1 
ATOM   3142 C  CA  . THR D 1 2   ? -18.455 -15.456 -30.438 1.00 67.81  ? 2   THR F CA  1 
ATOM   3143 C  C   . THR D 1 2   ? -19.933 -15.033 -30.587 1.00 65.65  ? 2   THR F C   1 
ATOM   3144 O  O   . THR D 1 2   ? -20.360 -14.598 -31.667 1.00 65.05  ? 2   THR F O   1 
ATOM   3145 C  CB  . THR D 1 2   ? -17.468 -14.338 -30.023 1.00 78.87  ? 2   THR F CB  1 
ATOM   3146 O  OG1 . THR D 1 2   ? -17.901 -13.736 -28.806 1.00 78.42  ? 2   THR F OG1 1 
ATOM   3147 C  CG2 . THR D 1 2   ? -17.257 -13.275 -31.099 1.00 79.76  ? 2   THR F CG2 1 
ATOM   3148 N  N   . LYS D 1 3   ? -20.719 -15.235 -29.517 1.00 57.81  ? 3   LYS F N   1 
ATOM   3149 C  CA  . LYS D 1 3   ? -22.154 -14.938 -29.487 1.00 54.97  ? 3   LYS F CA  1 
ATOM   3150 C  C   . LYS D 1 3   ? -22.543 -14.014 -28.342 1.00 55.45  ? 3   LYS F C   1 
ATOM   3151 O  O   . LYS D 1 3   ? -21.977 -14.079 -27.240 1.00 54.13  ? 3   LYS F O   1 
ATOM   3152 C  CB  . LYS D 1 3   ? -22.982 -16.229 -29.387 1.00 58.52  ? 3   LYS F CB  1 
ATOM   3153 C  CG  . LYS D 1 3   ? -22.943 -17.115 -30.620 1.00 73.85  ? 3   LYS F CG  1 
ATOM   3154 C  CD  . LYS D 1 3   ? -23.673 -18.423 -30.363 1.00 89.07  ? 3   LYS F CD  1 
ATOM   3155 C  CE  . LYS D 1 3   ? -23.670 -19.330 -31.568 1.00 108.47 ? 3   LYS F CE  1 
ATOM   3156 N  NZ  . LYS D 1 3   ? -24.454 -20.570 -31.326 1.00 121.92 ? 3   LYS F NZ  1 
ATOM   3157 N  N   . ALA D 1 4   ? -23.529 -13.163 -28.608 1.00 50.61  ? 4   ALA F N   1 
ATOM   3158 C  CA  . ALA D 1 4   ? -24.100 -12.252 -27.624 1.00 49.27  ? 4   ALA F CA  1 
ATOM   3159 C  C   . ALA D 1 4   ? -25.623 -12.244 -27.783 1.00 51.45  ? 4   ALA F C   1 
ATOM   3160 O  O   . ALA D 1 4   ? -26.139 -12.639 -28.833 1.00 52.12  ? 4   ALA F O   1 
ATOM   3161 C  CB  . ALA D 1 4   ? -23.522 -10.852 -27.781 1.00 49.03  ? 4   ALA F CB  1 
ATOM   3162 N  N   . VAL D 1 5   ? -26.333 -11.855 -26.713 1.00 46.81  ? 5   VAL F N   1 
ATOM   3163 C  CA  . VAL D 1 5   ? -27.795 -11.811 -26.656 1.00 46.67  ? 5   VAL F CA  1 
ATOM   3164 C  C   . VAL D 1 5   ? -28.234 -10.615 -25.803 1.00 49.73  ? 5   VAL F C   1 
ATOM   3165 O  O   . VAL D 1 5   ? -27.547 -10.220 -24.849 1.00 48.01  ? 5   VAL F O   1 
ATOM   3166 C  CB  . VAL D 1 5   ? -28.390 -13.170 -26.171 1.00 52.01  ? 5   VAL F CB  1 
ATOM   3167 C  CG1 . VAL D 1 5   ? -28.045 -13.455 -24.706 1.00 51.67  ? 5   VAL F CG1 1 
ATOM   3168 C  CG2 . VAL D 1 5   ? -29.900 -13.264 -26.418 1.00 52.82  ? 5   VAL F CG2 1 
ATOM   3169 N  N   . CYS D 1 6   ? -29.371 -10.035 -26.170 1.00 47.05  ? 6   CYS F N   1 
ATOM   3170 C  CA  . CYS D 1 6   ? -29.929 -8.888  -25.492 1.00 46.85  ? 6   CYS F CA  1 
ATOM   3171 C  C   . CYS D 1 6   ? -31.439 -9.014  -25.350 1.00 49.63  ? 6   CYS F C   1 
ATOM   3172 O  O   . CYS D 1 6   ? -32.144 -9.197  -26.343 1.00 49.25  ? 6   CYS F O   1 
ATOM   3173 C  CB  . CYS D 1 6   ? -29.541 -7.611  -26.228 1.00 47.38  ? 6   CYS F CB  1 
ATOM   3174 S  SG  . CYS D 1 6   ? -30.172 -6.105  -25.460 1.00 51.78  ? 6   CYS F SG  1 
ATOM   3175 N  N   . VAL D 1 7   ? -31.932 -8.892  -24.110 1.00 45.53  ? 7   VAL F N   1 
ATOM   3176 C  CA  . VAL D 1 7   ? -33.367 -8.929  -23.805 1.00 46.06  ? 7   VAL F CA  1 
ATOM   3177 C  C   . VAL D 1 7   ? -33.806 -7.470  -23.687 1.00 49.01  ? 7   VAL F C   1 
ATOM   3178 O  O   . VAL D 1 7   ? -33.320 -6.745  -22.813 1.00 46.22  ? 7   VAL F O   1 
ATOM   3179 C  CB  . VAL D 1 7   ? -33.670 -9.739  -22.504 1.00 50.56  ? 7   VAL F CB  1 
ATOM   3180 C  CG1 . VAL D 1 7   ? -35.162 -9.696  -22.146 1.00 52.29  ? 7   VAL F CG1 1 
ATOM   3181 C  CG2 . VAL D 1 7   ? -33.186 -11.184 -22.623 1.00 50.79  ? 7   VAL F CG2 1 
ATOM   3182 N  N   . LEU D 1 8   ? -34.728 -7.049  -24.558 1.00 48.30  ? 8   LEU F N   1 
ATOM   3183 C  CA  . LEU D 1 8   ? -35.269 -5.690  -24.594 1.00 49.03  ? 8   LEU F CA  1 
ATOM   3184 C  C   . LEU D 1 8   ? -36.563 -5.583  -23.771 1.00 54.23  ? 8   LEU F C   1 
ATOM   3185 O  O   . LEU D 1 8   ? -37.510 -6.345  -23.998 1.00 54.87  ? 8   LEU F O   1 
ATOM   3186 C  CB  . LEU D 1 8   ? -35.542 -5.242  -26.057 1.00 50.02  ? 8   LEU F CB  1 
ATOM   3187 C  CG  . LEU D 1 8   ? -34.360 -5.018  -27.061 1.00 55.52  ? 8   LEU F CG  1 
ATOM   3188 C  CD1 . LEU D 1 8   ? -33.418 -3.924  -26.617 1.00 54.11  ? 8   LEU F CD1 1 
ATOM   3189 C  CD2 . LEU D 1 8   ? -33.603 -6.296  -27.382 1.00 60.59  ? 8   LEU F CD2 1 
ATOM   3190 N  N   . LYS D 1 9   ? -36.592 -4.634  -22.818 1.00 50.70  ? 9   LYS F N   1 
ATOM   3191 C  CA  . LYS D 1 9   ? -37.745 -4.298  -21.968 1.00 52.56  ? 9   LYS F CA  1 
ATOM   3192 C  C   . LYS D 1 9   ? -37.753 -2.786  -21.768 1.00 56.58  ? 9   LYS F C   1 
ATOM   3193 O  O   . LYS D 1 9   ? -36.699 -2.146  -21.825 1.00 54.38  ? 9   LYS F O   1 
ATOM   3194 C  CB  . LYS D 1 9   ? -37.665 -4.990  -20.584 1.00 55.74  ? 9   LYS F CB  1 
ATOM   3195 C  CG  . LYS D 1 9   ? -37.919 -6.492  -20.599 1.00 72.92  ? 9   LYS F CG  1 
ATOM   3196 C  CD  . LYS D 1 9   ? -37.893 -7.078  -19.190 1.00 84.60  ? 9   LYS F CD  1 
ATOM   3197 C  CE  . LYS D 1 9   ? -37.527 -8.546  -19.163 1.00 97.55  ? 9   LYS F CE  1 
ATOM   3198 N  NZ  . LYS D 1 9   ? -38.588 -9.411  -19.747 1.00 107.32 ? 9   LYS F NZ  1 
ATOM   3199 N  N   . GLY D 1 10  ? -38.931 -2.240  -21.522 1.00 57.02  ? 10  GLY F N   1 
ATOM   3200 C  CA  . GLY D 1 10  ? -39.154 -0.821  -21.270 1.00 58.58  ? 10  GLY F CA  1 
ATOM   3201 C  C   . GLY D 1 10  ? -40.299 -0.604  -20.302 1.00 65.07  ? 10  GLY F C   1 
ATOM   3202 O  O   . GLY D 1 10  ? -40.734 -1.549  -19.636 1.00 65.22  ? 10  GLY F O   1 
ATOM   3203 N  N   . ASP D 1 11  ? -40.792 0.642   -20.212 1.00 63.32  ? 11  ASP F N   1 
ATOM   3204 C  CA  . ASP D 1 11  ? -41.915 0.998   -19.344 1.00 66.65  ? 11  ASP F CA  1 
ATOM   3205 C  C   . ASP D 1 11  ? -43.235 0.616   -20.009 1.00 72.04  ? 11  ASP F C   1 
ATOM   3206 O  O   . ASP D 1 11  ? -44.209 0.329   -19.311 1.00 74.42  ? 11  ASP F O   1 
ATOM   3207 C  CB  . ASP D 1 11  ? -41.894 2.497   -19.002 1.00 70.84  ? 11  ASP F CB  1 
ATOM   3208 C  CG  . ASP D 1 11  ? -40.756 2.936   -18.096 1.00 85.39  ? 11  ASP F CG  1 
ATOM   3209 O  OD1 . ASP D 1 11  ? -40.250 2.093   -17.318 1.00 85.61  ? 11  ASP F OD1 1 
ATOM   3210 O  OD2 . ASP D 1 11  ? -40.382 4.126   -18.152 1.00 94.39  ? 11  ASP F OD2 1 
ATOM   3211 N  N   . GLY D 1 12  ? -43.232 0.601   -21.344 1.00 66.76  ? 12  GLY F N   1 
ATOM   3212 C  CA  . GLY D 1 12  ? -44.375 0.260   -22.187 1.00 68.03  ? 12  GLY F CA  1 
ATOM   3213 C  C   . GLY D 1 12  ? -44.443 -1.212  -22.569 1.00 68.67  ? 12  GLY F C   1 
ATOM   3214 O  O   . GLY D 1 12  ? -43.859 -2.055  -21.877 1.00 65.37  ? 12  GLY F O   1 
ATOM   3215 N  N   . PRO D 1 13  ? -45.162 -1.562  -23.660 1.00 66.09  ? 13  PRO F N   1 
ATOM   3216 C  CA  . PRO D 1 13  ? -45.277 -2.982  -24.046 1.00 65.86  ? 13  PRO F CA  1 
ATOM   3217 C  C   . PRO D 1 13  ? -44.153 -3.521  -24.953 1.00 67.11  ? 13  PRO F C   1 
ATOM   3218 O  O   . PRO D 1 13  ? -44.208 -4.693  -25.348 1.00 66.53  ? 13  PRO F O   1 
ATOM   3219 C  CB  . PRO D 1 13  ? -46.617 -3.010  -24.790 1.00 70.80  ? 13  PRO F CB  1 
ATOM   3220 C  CG  . PRO D 1 13  ? -46.681 -1.672  -25.457 1.00 75.25  ? 13  PRO F CG  1 
ATOM   3221 C  CD  . PRO D 1 13  ? -45.940 -0.696  -24.581 1.00 69.75  ? 13  PRO F CD  1 
ATOM   3222 N  N   . VAL D 1 14  ? -43.180 -2.667  -25.341 1.00 61.51  ? 14  VAL F N   1 
ATOM   3223 C  CA  . VAL D 1 14  ? -42.087 -3.048  -26.252 1.00 59.47  ? 14  VAL F CA  1 
ATOM   3224 C  C   . VAL D 1 14  ? -41.172 -4.096  -25.606 1.00 62.83  ? 14  VAL F C   1 
ATOM   3225 O  O   . VAL D 1 14  ? -40.547 -3.827  -24.576 1.00 60.69  ? 14  VAL F O   1 
ATOM   3226 C  CB  . VAL D 1 14  ? -41.298 -1.831  -26.809 1.00 61.58  ? 14  VAL F CB  1 
ATOM   3227 C  CG1 . VAL D 1 14  ? -40.242 -2.281  -27.813 1.00 59.62  ? 14  VAL F CG1 1 
ATOM   3228 C  CG2 . VAL D 1 14  ? -42.234 -0.806  -27.442 1.00 64.25  ? 14  VAL F CG2 1 
ATOM   3229 N  N   . GLN D 1 15  ? -41.130 -5.301  -26.199 1.00 60.33  ? 15  GLN F N   1 
ATOM   3230 C  CA  . GLN D 1 15  ? -40.291 -6.386  -25.686 1.00 58.94  ? 15  GLN F CA  1 
ATOM   3231 C  C   . GLN D 1 15  ? -39.758 -7.272  -26.811 1.00 61.89  ? 15  GLN F C   1 
ATOM   3232 O  O   . GLN D 1 15  ? -40.425 -7.451  -27.827 1.00 63.32  ? 15  GLN F O   1 
ATOM   3233 C  CB  . GLN D 1 15  ? -40.992 -7.200  -24.571 1.00 61.07  ? 15  GLN F CB  1 
ATOM   3234 C  CG  . GLN D 1 15  ? -42.227 -7.992  -25.010 1.00 69.01  ? 15  GLN F CG  1 
ATOM   3235 C  CD  . GLN D 1 15  ? -42.786 -8.862  -23.909 1.00 90.44  ? 15  GLN F CD  1 
ATOM   3236 O  OE1 . GLN D 1 15  ? -42.087 -9.696  -23.317 1.00 86.53  ? 15  GLN F OE1 1 
ATOM   3237 N  NE2 . GLN D 1 15  ? -44.071 -8.700  -23.619 1.00 83.09  ? 15  GLN F NE2 1 
ATOM   3238 N  N   . GLY D 1 16  ? -38.558 -7.801  -26.615 1.00 56.18  ? 16  GLY F N   1 
ATOM   3239 C  CA  . GLY D 1 16  ? -37.916 -8.661  -27.599 1.00 55.45  ? 16  GLY F CA  1 
ATOM   3240 C  C   . GLY D 1 16  ? -36.588 -9.263  -27.183 1.00 56.12  ? 16  GLY F C   1 
ATOM   3241 O  O   . GLY D 1 16  ? -36.053 -8.959  -26.111 1.00 52.55  ? 16  GLY F O   1 
ATOM   3242 N  N   . ILE D 1 17  ? -36.067 -10.142 -28.053 1.00 52.71  ? 17  ILE F N   1 
ATOM   3243 C  CA  . ILE D 1 17  ? -34.803 -10.845 -27.910 1.00 51.54  ? 17  ILE F CA  1 
ATOM   3244 C  C   . ILE D 1 17  ? -34.008 -10.626 -29.187 1.00 52.80  ? 17  ILE F C   1 
ATOM   3245 O  O   . ILE D 1 17  ? -34.464 -10.994 -30.259 1.00 53.34  ? 17  ILE F O   1 
ATOM   3246 C  CB  . ILE D 1 17  ? -34.989 -12.360 -27.576 1.00 56.69  ? 17  ILE F CB  1 
ATOM   3247 C  CG1 . ILE D 1 17  ? -35.630 -12.550 -26.169 1.00 57.29  ? 17  ILE F CG1 1 
ATOM   3248 C  CG2 . ILE D 1 17  ? -33.646 -13.115 -27.676 1.00 57.01  ? 17  ILE F CG2 1 
ATOM   3249 C  CD1 . ILE D 1 17  ? -36.257 -13.940 -25.875 1.00 62.09  ? 17  ILE F CD1 1 
ATOM   3250 N  N   . ILE D 1 18  ? -32.829 -10.003 -29.059 1.00 46.83  ? 18  ILE F N   1 
ATOM   3251 C  CA  . ILE D 1 18  ? -31.912 -9.745  -30.169 1.00 45.65  ? 18  ILE F CA  1 
ATOM   3252 C  C   . ILE D 1 18  ? -30.604 -10.487 -29.932 1.00 49.68  ? 18  ILE F C   1 
ATOM   3253 O  O   . ILE D 1 18  ? -29.970 -10.333 -28.882 1.00 48.16  ? 18  ILE F O   1 
ATOM   3254 C  CB  . ILE D 1 18  ? -31.714 -8.225  -30.449 1.00 47.56  ? 18  ILE F CB  1 
ATOM   3255 C  CG1 . ILE D 1 18  ? -33.053 -7.507  -30.802 1.00 49.20  ? 18  ILE F CG1 1 
ATOM   3256 C  CG2 . ILE D 1 18  ? -30.640 -7.971  -31.524 1.00 47.95  ? 18  ILE F CG2 1 
ATOM   3257 C  CD1 . ILE D 1 18  ? -33.862 -8.067  -32.001 1.00 54.12  ? 18  ILE F CD1 1 
ATOM   3258 N  N   . ASN D 1 19  ? -30.245 -11.330 -30.901 1.00 47.51  ? 19  ASN F N   1 
ATOM   3259 C  CA  . ASN D 1 19  ? -29.039 -12.144 -30.932 1.00 47.51  ? 19  ASN F CA  1 
ATOM   3260 C  C   . ASN D 1 19  ? -27.986 -11.485 -31.784 1.00 51.58  ? 19  ASN F C   1 
ATOM   3261 O  O   . ASN D 1 19  ? -28.308 -10.775 -32.738 1.00 51.63  ? 19  ASN F O   1 
ATOM   3262 C  CB  . ASN D 1 19  ? -29.330 -13.529 -31.496 1.00 47.63  ? 19  ASN F CB  1 
ATOM   3263 C  CG  . ASN D 1 19  ? -30.540 -14.198 -30.908 1.00 64.20  ? 19  ASN F CG  1 
ATOM   3264 O  OD1 . ASN D 1 19  ? -31.653 -14.117 -31.452 1.00 56.55  ? 19  ASN F OD1 1 
ATOM   3265 N  ND2 . ASN D 1 19  ? -30.343 -14.869 -29.783 1.00 52.43  ? 19  ASN F ND2 1 
ATOM   3266 N  N   . PHE D 1 20  ? -26.722 -11.761 -31.457 1.00 48.38  ? 20  PHE F N   1 
ATOM   3267 C  CA  . PHE D 1 20  ? -25.533 -11.274 -32.152 1.00 48.06  ? 20  PHE F CA  1 
ATOM   3268 C  C   . PHE D 1 20  ? -24.590 -12.458 -32.361 1.00 54.97  ? 20  PHE F C   1 
ATOM   3269 O  O   . PHE D 1 20  ? -24.450 -13.299 -31.470 1.00 55.92  ? 20  PHE F O   1 
ATOM   3270 C  CB  . PHE D 1 20  ? -24.815 -10.189 -31.313 1.00 48.12  ? 20  PHE F CB  1 
ATOM   3271 C  CG  . PHE D 1 20  ? -25.654 -8.985  -30.950 1.00 48.27  ? 20  PHE F CG  1 
ATOM   3272 C  CD1 . PHE D 1 20  ? -26.440 -8.983  -29.800 1.00 49.48  ? 20  PHE F CD1 1 
ATOM   3273 C  CD2 . PHE D 1 20  ? -25.639 -7.842  -31.743 1.00 49.90  ? 20  PHE F CD2 1 
ATOM   3274 C  CE1 . PHE D 1 20  ? -27.219 -7.872  -29.464 1.00 49.14  ? 20  PHE F CE1 1 
ATOM   3275 C  CE2 . PHE D 1 20  ? -26.412 -6.728  -31.402 1.00 51.85  ? 20  PHE F CE2 1 
ATOM   3276 C  CZ  . PHE D 1 20  ? -27.184 -6.747  -30.255 1.00 48.81  ? 20  PHE F CZ  1 
ATOM   3277 N  N   . GLU D 1 21  ? -23.948 -12.526 -33.529 1.00 52.88  ? 21  GLU F N   1 
ATOM   3278 C  CA  . GLU D 1 21  ? -22.985 -13.578 -33.845 1.00 54.99  ? 21  GLU F CA  1 
ATOM   3279 C  C   . GLU D 1 21  ? -21.848 -13.034 -34.705 1.00 58.81  ? 21  GLU F C   1 
ATOM   3280 O  O   . GLU D 1 21  ? -22.093 -12.330 -35.678 1.00 57.86  ? 21  GLU F O   1 
ATOM   3281 C  CB  . GLU D 1 21  ? -23.652 -14.789 -34.518 1.00 58.79  ? 21  GLU F CB  1 
ATOM   3282 C  CG  . GLU D 1 21  ? -22.833 -16.064 -34.360 1.00 72.46  ? 21  GLU F CG  1 
ATOM   3283 C  CD  . GLU D 1 21  ? -23.271 -17.284 -35.149 1.00 98.39  ? 21  GLU F CD  1 
ATOM   3284 O  OE1 . GLU D 1 21  ? -23.975 -17.127 -36.173 1.00 101.48 ? 21  GLU F OE1 1 
ATOM   3285 O  OE2 . GLU D 1 21  ? -22.884 -18.405 -34.747 1.00 93.49  ? 21  GLU F OE2 1 
ATOM   3286 N  N   . GLN D 1 22  ? -20.608 -13.356 -34.332 1.00 56.93  ? 22  GLN F N   1 
ATOM   3287 C  CA  . GLN D 1 22  ? -19.420 -12.938 -35.070 1.00 58.36  ? 22  GLN F CA  1 
ATOM   3288 C  C   . GLN D 1 22  ? -18.497 -14.145 -35.220 1.00 64.96  ? 22  GLN F C   1 
ATOM   3289 O  O   . GLN D 1 22  ? -17.952 -14.636 -34.228 1.00 64.81  ? 22  GLN F O   1 
ATOM   3290 C  CB  . GLN D 1 22  ? -18.726 -11.774 -34.352 1.00 58.19  ? 22  GLN F CB  1 
ATOM   3291 C  CG  . GLN D 1 22  ? -17.767 -10.976 -35.237 1.00 57.33  ? 22  GLN F CG  1 
ATOM   3292 C  CD  . GLN D 1 22  ? -17.049 -9.914  -34.438 1.00 61.95  ? 22  GLN F CD  1 
ATOM   3293 O  OE1 . GLN D 1 22  ? -17.035 -9.935  -33.209 1.00 55.43  ? 22  GLN F OE1 1 
ATOM   3294 N  NE2 . GLN D 1 22  ? -16.438 -8.953  -35.112 1.00 52.93  ? 22  GLN F NE2 1 
ATOM   3295 N  N   . LYS D 1 23  ? -18.393 -14.657 -36.450 1.00 64.26  ? 23  LYS F N   1 
ATOM   3296 C  CA  . LYS D 1 23  ? -17.585 -15.827 -36.821 1.00 67.29  ? 23  LYS F CA  1 
ATOM   3297 C  C   . LYS D 1 23  ? -16.080 -15.588 -36.673 1.00 71.14  ? 23  LYS F C   1 
ATOM   3298 O  O   . LYS D 1 23  ? -15.379 -16.465 -36.172 1.00 73.57  ? 23  LYS F O   1 
ATOM   3299 C  CB  . LYS D 1 23  ? -17.930 -16.298 -38.248 1.00 72.14  ? 23  LYS F CB  1 
ATOM   3300 C  CG  . LYS D 1 23  ? -19.257 -17.051 -38.340 1.00 89.07  ? 23  LYS F CG  1 
ATOM   3301 C  CD  . LYS D 1 23  ? -19.708 -17.277 -39.788 1.00 105.40 ? 23  LYS F CD  1 
ATOM   3302 C  CE  . LYS D 1 23  ? -19.229 -18.587 -40.374 1.00 123.03 ? 23  LYS F CE  1 
ATOM   3303 N  NZ  . LYS D 1 23  ? -19.644 -18.744 -41.794 1.00 134.24 ? 23  LYS F NZ  1 
ATOM   3304 N  N   . GLU D 1 24  ? -15.591 -14.412 -37.107 1.00 65.44  ? 24  GLU F N   1 
ATOM   3305 C  CA  . GLU D 1 24  ? -14.183 -14.008 -37.027 1.00 66.18  ? 24  GLU F CA  1 
ATOM   3306 C  C   . GLU D 1 24  ? -14.082 -12.635 -36.373 1.00 66.05  ? 24  GLU F C   1 
ATOM   3307 O  O   . GLU D 1 24  ? -14.943 -11.787 -36.616 1.00 63.36  ? 24  GLU F O   1 
ATOM   3308 C  CB  . GLU D 1 24  ? -13.527 -13.991 -38.422 1.00 70.49  ? 24  GLU F CB  1 
ATOM   3309 C  CG  . GLU D 1 24  ? -13.175 -15.373 -38.946 1.00 86.07  ? 24  GLU F CG  1 
ATOM   3310 C  CD  . GLU D 1 24  ? -13.720 -15.714 -40.321 1.00 113.42 ? 24  GLU F CD  1 
ATOM   3311 O  OE1 . GLU D 1 24  ? -14.891 -15.373 -40.608 1.00 114.09 ? 24  GLU F OE1 1 
ATOM   3312 O  OE2 . GLU D 1 24  ? -12.977 -16.341 -41.109 1.00 112.34 ? 24  GLU F OE2 1 
ATOM   3313 N  N   . SER D 1 25  ? -13.022 -12.413 -35.555 1.00 62.10  ? 25  SER F N   1 
ATOM   3314 C  CA  . SER D 1 25  ? -12.775 -11.161 -34.823 1.00 60.27  ? 25  SER F CA  1 
ATOM   3315 C  C   . SER D 1 25  ? -12.689 -9.920  -35.719 1.00 64.66  ? 25  SER F C   1 
ATOM   3316 O  O   . SER D 1 25  ? -13.122 -8.847  -35.303 1.00 62.64  ? 25  SER F O   1 
ATOM   3317 C  CB  . SER D 1 25  ? -11.541 -11.278 -33.929 1.00 63.92  ? 25  SER F CB  1 
ATOM   3318 O  OG  . SER D 1 25  ? -10.338 -11.394 -34.673 1.00 75.25  ? 25  SER F OG  1 
ATOM   3319 N  N   . ASN D 1 26  ? -12.154 -10.067 -36.947 1.00 64.36  ? 26  ASN F N   1 
ATOM   3320 C  CA  . ASN D 1 26  ? -12.054 -8.966  -37.909 1.00 64.68  ? 26  ASN F CA  1 
ATOM   3321 C  C   . ASN D 1 26  ? -13.180 -9.033  -38.973 1.00 68.15  ? 26  ASN F C   1 
ATOM   3322 O  O   . ASN D 1 26  ? -13.112 -8.349  -39.999 1.00 69.13  ? 26  ASN F O   1 
ATOM   3323 C  CB  . ASN D 1 26  ? -10.644 -8.912  -38.539 1.00 66.55  ? 26  ASN F CB  1 
ATOM   3324 C  CG  . ASN D 1 26  ? -10.274 -10.091 -39.409 1.00 76.02  ? 26  ASN F CG  1 
ATOM   3325 O  OD1 . ASN D 1 26  ? -10.687 -11.231 -39.168 1.00 64.57  ? 26  ASN F OD1 1 
ATOM   3326 N  ND2 . ASN D 1 26  ? -9.468  -9.841  -40.442 1.00 68.85  ? 26  ASN F ND2 1 
ATOM   3327 N  N   . GLY D 1 27  ? -14.200 -9.844  -38.696 1.00 62.96  ? 27  GLY F N   1 
ATOM   3328 C  CA  . GLY D 1 27  ? -15.339 -10.061 -39.581 1.00 62.92  ? 27  GLY F CA  1 
ATOM   3329 C  C   . GLY D 1 27  ? -16.647 -9.415  -39.153 1.00 65.13  ? 27  GLY F C   1 
ATOM   3330 O  O   . GLY D 1 27  ? -16.769 -8.909  -38.026 1.00 63.44  ? 27  GLY F O   1 
ATOM   3331 N  N   . PRO D 1 28  ? -17.670 -9.439  -40.044 1.00 62.04  ? 28  PRO F N   1 
ATOM   3332 C  CA  . PRO D 1 28  ? -18.956 -8.806  -39.705 1.00 59.57  ? 28  PRO F CA  1 
ATOM   3333 C  C   . PRO D 1 28  ? -19.743 -9.485  -38.579 1.00 60.45  ? 28  PRO F C   1 
ATOM   3334 O  O   . PRO D 1 28  ? -19.506 -10.648 -38.246 1.00 59.40  ? 28  PRO F O   1 
ATOM   3335 C  CB  . PRO D 1 28  ? -19.723 -8.814  -41.034 1.00 62.35  ? 28  PRO F CB  1 
ATOM   3336 C  CG  . PRO D 1 28  ? -19.131 -9.922  -41.808 1.00 69.23  ? 28  PRO F CG  1 
ATOM   3337 C  CD  . PRO D 1 28  ? -17.683 -9.987  -41.419 1.00 65.73  ? 28  PRO F CD  1 
ATOM   3338 N  N   . VAL D 1 29  ? -20.671 -8.732  -37.986 1.00 56.23  ? 29  VAL F N   1 
ATOM   3339 C  CA  . VAL D 1 29  ? -21.537 -9.215  -36.911 1.00 54.99  ? 29  VAL F CA  1 
ATOM   3340 C  C   . VAL D 1 29  ? -22.956 -9.383  -37.459 1.00 59.17  ? 29  VAL F C   1 
ATOM   3341 O  O   . VAL D 1 29  ? -23.523 -8.432  -37.999 1.00 59.56  ? 29  VAL F O   1 
ATOM   3342 C  CB  . VAL D 1 29  ? -21.520 -8.297  -35.650 1.00 56.43  ? 29  VAL F CB  1 
ATOM   3343 C  CG1 . VAL D 1 29  ? -22.418 -8.851  -34.540 1.00 54.95  ? 29  VAL F CG1 1 
ATOM   3344 C  CG2 . VAL D 1 29  ? -20.103 -8.072  -35.138 1.00 56.17  ? 29  VAL F CG2 1 
ATOM   3345 N  N   . LYS D 1 30  ? -23.527 -10.585 -37.292 1.00 56.28  ? 30  LYS F N   1 
ATOM   3346 C  CA  . LYS D 1 30  ? -24.904 -10.915 -37.667 1.00 56.88  ? 30  LYS F CA  1 
ATOM   3347 C  C   . LYS D 1 30  ? -25.815 -10.554 -36.474 1.00 58.91  ? 30  LYS F C   1 
ATOM   3348 O  O   . LYS D 1 30  ? -25.536 -10.965 -35.343 1.00 55.49  ? 30  LYS F O   1 
ATOM   3349 C  CB  . LYS D 1 30  ? -25.008 -12.415 -38.006 1.00 62.17  ? 30  LYS F CB  1 
ATOM   3350 C  CG  . LYS D 1 30  ? -26.328 -12.846 -38.641 1.00 88.02  ? 30  LYS F CG  1 
ATOM   3351 C  CD  . LYS D 1 30  ? -26.230 -14.241 -39.280 1.00 104.35 ? 30  LYS F CD  1 
ATOM   3352 C  CE  . LYS D 1 30  ? -26.511 -15.386 -38.326 1.00 116.75 ? 30  LYS F CE  1 
ATOM   3353 N  NZ  . LYS D 1 30  ? -27.966 -15.546 -38.059 1.00 126.01 ? 30  LYS F NZ  1 
ATOM   3354 N  N   . VAL D 1 31  ? -26.880 -9.765  -36.719 1.00 56.01  ? 31  VAL F N   1 
ATOM   3355 C  CA  . VAL D 1 31  ? -27.809 -9.358  -35.659 1.00 55.26  ? 31  VAL F CA  1 
ATOM   3356 C  C   . VAL D 1 31  ? -29.243 -9.686  -36.093 1.00 59.51  ? 31  VAL F C   1 
ATOM   3357 O  O   . VAL D 1 31  ? -29.735 -9.185  -37.107 1.00 59.92  ? 31  VAL F O   1 
ATOM   3358 C  CB  . VAL D 1 31  ? -27.604 -7.909  -35.100 1.00 58.52  ? 31  VAL F CB  1 
ATOM   3359 C  CG1 . VAL D 1 31  ? -27.027 -6.946  -36.121 1.00 59.69  ? 31  VAL F CG1 1 
ATOM   3360 C  CG2 . VAL D 1 31  ? -28.850 -7.341  -34.433 1.00 57.72  ? 31  VAL F CG2 1 
ATOM   3361 N  N   . TRP D 1 32  ? -29.884 -10.591 -35.340 1.00 55.67  ? 32  TRP F N   1 
ATOM   3362 C  CA  . TRP D 1 32  ? -31.230 -11.068 -35.651 1.00 57.04  ? 32  TRP F CA  1 
ATOM   3363 C  C   . TRP D 1 32  ? -32.073 -11.306 -34.406 1.00 58.67  ? 32  TRP F C   1 
ATOM   3364 O  O   . TRP D 1 32  ? -31.537 -11.474 -33.313 1.00 55.52  ? 32  TRP F O   1 
ATOM   3365 C  CB  . TRP D 1 32  ? -31.168 -12.337 -36.531 1.00 58.39  ? 32  TRP F CB  1 
ATOM   3366 C  CG  . TRP D 1 32  ? -30.880 -13.599 -35.768 1.00 60.05  ? 32  TRP F CG  1 
ATOM   3367 C  CD1 . TRP D 1 32  ? -31.780 -14.551 -35.388 1.00 64.71  ? 32  TRP F CD1 1 
ATOM   3368 C  CD2 . TRP D 1 32  ? -29.605 -14.029 -35.272 1.00 59.22  ? 32  TRP F CD2 1 
ATOM   3369 N  NE1 . TRP D 1 32  ? -31.144 -15.552 -34.693 1.00 64.73  ? 32  TRP F NE1 1 
ATOM   3370 C  CE2 . TRP D 1 32  ? -29.807 -15.262 -34.613 1.00 64.52  ? 32  TRP F CE2 1 
ATOM   3371 C  CE3 . TRP D 1 32  ? -28.300 -13.512 -35.359 1.00 59.33  ? 32  TRP F CE3 1 
ATOM   3372 C  CZ2 . TRP D 1 32  ? -28.756 -15.981 -34.031 1.00 64.06  ? 32  TRP F CZ2 1 
ATOM   3373 C  CZ3 . TRP D 1 32  ? -27.262 -14.213 -34.763 1.00 61.17  ? 32  TRP F CZ3 1 
ATOM   3374 C  CH2 . TRP D 1 32  ? -27.494 -15.427 -34.098 1.00 63.19  ? 32  TRP F CH2 1 
ATOM   3375 N  N   . GLY D 1 33  ? -33.383 -11.368 -34.603 1.00 56.13  ? 33  GLY F N   1 
ATOM   3376 C  CA  . GLY D 1 33  ? -34.337 -11.608 -33.535 1.00 56.07  ? 33  GLY F CA  1 
ATOM   3377 C  C   . GLY D 1 33  ? -35.696 -11.019 -33.822 1.00 61.07  ? 33  GLY F C   1 
ATOM   3378 O  O   . GLY D 1 33  ? -36.016 -10.724 -34.976 1.00 61.58  ? 33  GLY F O   1 
ATOM   3379 N  N   . SER D 1 34  ? -36.502 -10.841 -32.772 1.00 58.28  ? 34  SER F N   1 
ATOM   3380 C  CA  . SER D 1 34  ? -37.862 -10.315 -32.916 1.00 60.82  ? 34  SER F CA  1 
ATOM   3381 C  C   . SER D 1 34  ? -38.221 -9.396  -31.746 1.00 63.39  ? 34  SER F C   1 
ATOM   3382 O  O   . SER D 1 34  ? -37.770 -9.620  -30.625 1.00 61.41  ? 34  SER F O   1 
ATOM   3383 C  CB  . SER D 1 34  ? -38.860 -11.462 -33.040 1.00 67.95  ? 34  SER F CB  1 
ATOM   3384 O  OG  . SER D 1 34  ? -40.178 -11.002 -33.282 1.00 85.42  ? 34  SER F OG  1 
ATOM   3385 N  N   . ILE D 1 35  ? -38.994 -8.329  -32.041 1.00 59.71  ? 35  ILE F N   1 
ATOM   3386 C  CA  . ILE D 1 35  ? -39.454 -7.304  -31.100 1.00 58.11  ? 35  ILE F CA  1 
ATOM   3387 C  C   . ILE D 1 35  ? -40.944 -7.082  -31.348 1.00 65.33  ? 35  ILE F C   1 
ATOM   3388 O  O   . ILE D 1 35  ? -41.344 -6.837  -32.481 1.00 66.62  ? 35  ILE F O   1 
ATOM   3389 C  CB  . ILE D 1 35  ? -38.666 -5.963  -31.247 1.00 58.96  ? 35  ILE F CB  1 
ATOM   3390 C  CG1 . ILE D 1 35  ? -37.122 -6.161  -31.223 1.00 57.30  ? 35  ILE F CG1 1 
ATOM   3391 C  CG2 . ILE D 1 35  ? -39.120 -4.927  -30.199 1.00 58.43  ? 35  ILE F CG2 1 
ATOM   3392 C  CD1 . ILE D 1 35  ? -36.344 -5.089  -31.973 1.00 62.91  ? 35  ILE F CD1 1 
ATOM   3393 N  N   . LYS D 1 36  ? -41.754 -7.144  -30.287 1.00 63.30  ? 36  LYS F N   1 
ATOM   3394 C  CA  . LYS D 1 36  ? -43.197 -6.919  -30.384 1.00 65.15  ? 36  LYS F CA  1 
ATOM   3395 C  C   . LYS D 1 36  ? -43.606 -5.717  -29.510 1.00 68.53  ? 36  LYS F C   1 
ATOM   3396 O  O   . LYS D 1 36  ? -42.773 -5.209  -28.745 1.00 64.60  ? 36  LYS F O   1 
ATOM   3397 C  CB  . LYS D 1 36  ? -43.976 -8.204  -30.039 1.00 69.40  ? 36  LYS F CB  1 
ATOM   3398 C  CG  . LYS D 1 36  ? -43.827 -8.687  -28.593 1.00 78.21  ? 36  LYS F CG  1 
ATOM   3399 C  CD  . LYS D 1 36  ? -44.734 -9.872  -28.309 1.00 91.24  ? 36  LYS F CD  1 
ATOM   3400 C  CE  . LYS D 1 36  ? -44.741 -10.283 -26.861 1.00 99.49  ? 36  LYS F CE  1 
ATOM   3401 N  NZ  . LYS D 1 36  ? -45.681 -11.409 -26.633 1.00 114.18 ? 36  LYS F NZ  1 
ATOM   3402 N  N   . GLY D 1 37  ? -44.857 -5.266  -29.656 1.00 67.55  ? 37  GLY F N   1 
ATOM   3403 C  CA  . GLY D 1 37  ? -45.415 -4.139  -28.906 1.00 67.81  ? 37  GLY F CA  1 
ATOM   3404 C  C   . GLY D 1 37  ? -45.128 -2.788  -29.532 1.00 69.10  ? 37  GLY F C   1 
ATOM   3405 O  O   . GLY D 1 37  ? -45.342 -1.744  -28.908 1.00 67.81  ? 37  GLY F O   1 
ATOM   3406 N  N   . LEU D 1 38  ? -44.601 -2.811  -30.760 1.00 65.32  ? 38  LEU F N   1 
ATOM   3407 C  CA  . LEU D 1 38  ? -44.209 -1.644  -31.536 1.00 65.67  ? 38  LEU F CA  1 
ATOM   3408 C  C   . LEU D 1 38  ? -45.358 -1.136  -32.396 1.00 73.71  ? 38  LEU F C   1 
ATOM   3409 O  O   . LEU D 1 38  ? -46.177 -1.927  -32.867 1.00 75.02  ? 38  LEU F O   1 
ATOM   3410 C  CB  . LEU D 1 38  ? -43.082 -2.093  -32.485 1.00 63.84  ? 38  LEU F CB  1 
ATOM   3411 C  CG  . LEU D 1 38  ? -41.629 -1.548  -32.357 1.00 65.56  ? 38  LEU F CG  1 
ATOM   3412 C  CD1 . LEU D 1 38  ? -41.319 -0.938  -31.049 1.00 63.04  ? 38  LEU F CD1 1 
ATOM   3413 C  CD2 . LEU D 1 38  ? -40.624 -2.602  -32.727 1.00 66.41  ? 38  LEU F CD2 1 
ATOM   3414 N  N   . THR D 1 39  ? -45.374 0.173   -32.678 1.00 72.13  ? 39  THR F N   1 
ATOM   3415 C  CA  . THR D 1 39  ? -46.350 0.748   -33.601 1.00 75.85  ? 39  THR F CA  1 
ATOM   3416 C  C   . THR D 1 39  ? -45.826 0.403   -34.992 1.00 80.17  ? 39  THR F C   1 
ATOM   3417 O  O   . THR D 1 39  ? -44.602 0.365   -35.189 1.00 76.57  ? 39  THR F O   1 
ATOM   3418 C  CB  . THR D 1 39  ? -46.490 2.270   -33.406 1.00 85.37  ? 39  THR F CB  1 
ATOM   3419 O  OG1 . THR D 1 39  ? -45.240 2.903   -33.673 1.00 85.94  ? 39  THR F OG1 1 
ATOM   3420 C  CG2 . THR D 1 39  ? -46.962 2.648   -32.005 1.00 82.37  ? 39  THR F CG2 1 
ATOM   3421 N  N   . GLU D 1 40  ? -46.729 0.103   -35.940 1.00 78.86  ? 40  GLU F N   1 
ATOM   3422 C  CA  . GLU D 1 40  ? -46.354 -0.235  -37.314 1.00 79.34  ? 40  GLU F CA  1 
ATOM   3423 C  C   . GLU D 1 40  ? -45.435 0.856   -37.892 1.00 82.81  ? 40  GLU F C   1 
ATOM   3424 O  O   . GLU D 1 40  ? -45.708 2.044   -37.720 1.00 85.11  ? 40  GLU F O   1 
ATOM   3425 C  CB  . GLU D 1 40  ? -47.616 -0.398  -38.183 1.00 85.37  ? 40  GLU F CB  1 
ATOM   3426 C  CG  . GLU D 1 40  ? -47.348 -1.080  -39.517 1.00 94.74  ? 40  GLU F CG  1 
ATOM   3427 C  CD  . GLU D 1 40  ? -48.503 -1.166  -40.500 1.00 109.89 ? 40  GLU F CD  1 
ATOM   3428 O  OE1 . GLU D 1 40  ? -49.680 -1.099  -40.074 1.00 97.81  ? 40  GLU F OE1 1 
ATOM   3429 O  OE2 . GLU D 1 40  ? -48.221 -1.321  -41.709 1.00 99.06  ? 40  GLU F OE2 1 
ATOM   3430 N  N   . GLY D 1 41  ? -44.334 0.437   -38.509 1.00 76.03  ? 41  GLY F N   1 
ATOM   3431 C  CA  . GLY D 1 41  ? -43.384 1.353   -39.128 1.00 75.26  ? 41  GLY F CA  1 
ATOM   3432 C  C   . GLY D 1 41  ? -41.948 1.226   -38.666 1.00 74.18  ? 41  GLY F C   1 
ATOM   3433 O  O   . GLY D 1 41  ? -41.580 0.253   -38.003 1.00 70.49  ? 41  GLY F O   1 
ATOM   3434 N  N   . LEU D 1 42  ? -41.140 2.245   -39.004 1.00 71.32  ? 42  LEU F N   1 
ATOM   3435 C  CA  . LEU D 1 42  ? -39.702 2.355   -38.730 1.00 68.51  ? 42  LEU F CA  1 
ATOM   3436 C  C   . LEU D 1 42  ? -39.387 2.874   -37.323 1.00 68.38  ? 42  LEU F C   1 
ATOM   3437 O  O   . LEU D 1 42  ? -39.984 3.855   -36.876 1.00 67.23  ? 42  LEU F O   1 
ATOM   3438 C  CB  . LEU D 1 42  ? -39.075 3.279   -39.791 1.00 70.73  ? 42  LEU F CB  1 
ATOM   3439 C  CG  . LEU D 1 42  ? -38.438 2.636   -41.034 1.00 76.23  ? 42  LEU F CG  1 
ATOM   3440 C  CD1 . LEU D 1 42  ? -39.487 2.093   -42.001 1.00 79.15  ? 42  LEU F CD1 1 
ATOM   3441 C  CD2 . LEU D 1 42  ? -37.641 3.660   -41.791 1.00 81.99  ? 42  LEU F CD2 1 
ATOM   3442 N  N   . HIS D 1 43  ? -38.429 2.215   -36.629 1.00 62.25  ? 43  HIS F N   1 
ATOM   3443 C  CA  . HIS D 1 43  ? -38.000 2.596   -35.283 1.00 60.13  ? 43  HIS F CA  1 
ATOM   3444 C  C   . HIS D 1 43  ? -36.491 2.555   -35.188 1.00 60.79  ? 43  HIS F C   1 
ATOM   3445 O  O   . HIS D 1 43  ? -35.887 1.523   -35.503 1.00 57.94  ? 43  HIS F O   1 
ATOM   3446 C  CB  . HIS D 1 43  ? -38.629 1.670   -34.219 1.00 59.80  ? 43  HIS F CB  1 
ATOM   3447 C  CG  . HIS D 1 43  ? -40.118 1.796   -34.146 1.00 65.47  ? 43  HIS F CG  1 
ATOM   3448 N  ND1 . HIS D 1 43  ? -40.719 2.795   -33.405 1.00 68.49  ? 43  HIS F ND1 1 
ATOM   3449 C  CD2 . HIS D 1 43  ? -41.079 1.077   -34.772 1.00 68.58  ? 43  HIS F CD2 1 
ATOM   3450 C  CE1 . HIS D 1 43  ? -42.022 2.647   -33.596 1.00 70.42  ? 43  HIS F CE1 1 
ATOM   3451 N  NE2 . HIS D 1 43  ? -42.286 1.622   -34.402 1.00 70.81  ? 43  HIS F NE2 1 
ATOM   3452 N  N   . GLY D 1 44  ? -35.894 3.667   -34.750 1.00 57.43  ? 44  GLY F N   1 
ATOM   3453 C  CA  . GLY D 1 44  ? -34.449 3.779   -34.568 1.00 55.19  ? 44  GLY F CA  1 
ATOM   3454 C  C   . GLY D 1 44  ? -33.923 2.640   -33.712 1.00 56.30  ? 44  GLY F C   1 
ATOM   3455 O  O   . GLY D 1 44  ? -34.569 2.255   -32.729 1.00 54.69  ? 44  GLY F O   1 
ATOM   3456 N  N   . PHE D 1 45  ? -32.786 2.053   -34.124 1.00 51.42  ? 45  PHE F N   1 
ATOM   3457 C  CA  . PHE D 1 45  ? -32.164 0.894   -33.475 1.00 49.47  ? 45  PHE F CA  1 
ATOM   3458 C  C   . PHE D 1 45  ? -30.672 1.193   -33.242 1.00 53.24  ? 45  PHE F C   1 
ATOM   3459 O  O   . PHE D 1 45  ? -29.868 1.174   -34.183 1.00 51.10  ? 45  PHE F O   1 
ATOM   3460 C  CB  . PHE D 1 45  ? -32.379 -0.334  -34.386 1.00 51.41  ? 45  PHE F CB  1 
ATOM   3461 C  CG  . PHE D 1 45  ? -32.183 -1.710  -33.793 1.00 51.14  ? 45  PHE F CG  1 
ATOM   3462 C  CD1 . PHE D 1 45  ? -32.842 -2.083  -32.621 1.00 53.06  ? 45  PHE F CD1 1 
ATOM   3463 C  CD2 . PHE D 1 45  ? -31.420 -2.666  -34.459 1.00 52.11  ? 45  PHE F CD2 1 
ATOM   3464 C  CE1 . PHE D 1 45  ? -32.714 -3.376  -32.111 1.00 52.79  ? 45  PHE F CE1 1 
ATOM   3465 C  CE2 . PHE D 1 45  ? -31.300 -3.962  -33.954 1.00 54.38  ? 45  PHE F CE2 1 
ATOM   3466 C  CZ  . PHE D 1 45  ? -31.934 -4.305  -32.773 1.00 52.15  ? 45  PHE F CZ  1 
ATOM   3467 N  N   . HIS D 1 46  ? -30.316 1.526   -31.989 1.00 50.53  ? 46  HIS F N   1 
ATOM   3468 C  CA  . HIS D 1 46  ? -28.955 1.940   -31.662 1.00 50.63  ? 46  HIS F CA  1 
ATOM   3469 C  C   . HIS D 1 46  ? -28.326 1.255   -30.475 1.00 51.37  ? 46  HIS F C   1 
ATOM   3470 O  O   . HIS D 1 46  ? -29.014 0.896   -29.523 1.00 49.87  ? 46  HIS F O   1 
ATOM   3471 C  CB  . HIS D 1 46  ? -28.915 3.461   -31.429 1.00 54.07  ? 46  HIS F CB  1 
ATOM   3472 C  CG  . HIS D 1 46  ? -29.345 4.269   -32.612 1.00 60.28  ? 46  HIS F CG  1 
ATOM   3473 N  ND1 . HIS D 1 46  ? -30.608 4.825   -32.682 1.00 64.07  ? 46  HIS F ND1 1 
ATOM   3474 C  CD2 . HIS D 1 46  ? -28.677 4.556   -33.752 1.00 63.50  ? 46  HIS F CD2 1 
ATOM   3475 C  CE1 . HIS D 1 46  ? -30.665 5.442   -33.850 1.00 65.22  ? 46  HIS F CE1 1 
ATOM   3476 N  NE2 . HIS D 1 46  ? -29.525 5.309   -34.529 1.00 65.57  ? 46  HIS F NE2 1 
ATOM   3477 N  N   . VAL D 1 47  ? -26.991 1.114   -30.523 1.00 47.30  ? 47  VAL F N   1 
ATOM   3478 C  CA  . VAL D 1 47  ? -26.194 0.630   -29.403 1.00 45.28  ? 47  VAL F CA  1 
ATOM   3479 C  C   . VAL D 1 47  ? -25.762 1.924   -28.706 1.00 49.85  ? 47  VAL F C   1 
ATOM   3480 O  O   . VAL D 1 47  ? -25.205 2.816   -29.350 1.00 50.04  ? 47  VAL F O   1 
ATOM   3481 C  CB  . VAL D 1 47  ? -24.962 -0.244  -29.801 1.00 47.98  ? 47  VAL F CB  1 
ATOM   3482 C  CG1 . VAL D 1 47  ? -24.153 -0.651  -28.568 1.00 46.04  ? 47  VAL F CG1 1 
ATOM   3483 C  CG2 . VAL D 1 47  ? -25.381 -1.479  -30.601 1.00 47.28  ? 47  VAL F CG2 1 
ATOM   3484 N  N   . HIS D 1 48  ? -26.091 2.049   -27.418 1.00 46.15  ? 48  HIS F N   1 
ATOM   3485 C  CA  . HIS D 1 48  ? -25.739 3.193   -26.586 1.00 47.58  ? 48  HIS F CA  1 
ATOM   3486 C  C   . HIS D 1 48  ? -24.512 2.841   -25.713 1.00 52.81  ? 48  HIS F C   1 
ATOM   3487 O  O   . HIS D 1 48  ? -24.292 1.667   -25.398 1.00 49.90  ? 48  HIS F O   1 
ATOM   3488 C  CB  . HIS D 1 48  ? -26.962 3.688   -25.787 1.00 48.25  ? 48  HIS F CB  1 
ATOM   3489 C  CG  . HIS D 1 48  ? -28.015 4.326   -26.664 1.00 52.28  ? 48  HIS F CG  1 
ATOM   3490 N  ND1 . HIS D 1 48  ? -28.336 5.670   -26.551 1.00 56.01  ? 48  HIS F ND1 1 
ATOM   3491 C  CD2 . HIS D 1 48  ? -28.746 3.793   -27.673 1.00 52.46  ? 48  HIS F CD2 1 
ATOM   3492 C  CE1 . HIS D 1 48  ? -29.262 5.899   -27.471 1.00 55.84  ? 48  HIS F CE1 1 
ATOM   3493 N  NE2 . HIS D 1 48  ? -29.548 4.800   -28.164 1.00 54.22  ? 48  HIS F NE2 1 
ATOM   3494 N  N   . GLU D 1 49  ? -23.679 3.854   -25.410 1.00 53.21  ? 49  GLU F N   1 
ATOM   3495 C  CA  . GLU D 1 49  ? -22.402 3.759   -24.697 1.00 53.97  ? 49  GLU F CA  1 
ATOM   3496 C  C   . GLU D 1 49  ? -22.410 2.972   -23.381 1.00 58.05  ? 49  GLU F C   1 
ATOM   3497 O  O   . GLU D 1 49  ? -21.480 2.199   -23.150 1.00 58.15  ? 49  GLU F O   1 
ATOM   3498 C  CB  . GLU D 1 49  ? -21.818 5.159   -24.447 1.00 58.09  ? 49  GLU F CB  1 
ATOM   3499 C  CG  . GLU D 1 49  ? -20.306 5.152   -24.282 1.00 68.85  ? 49  GLU F CG  1 
ATOM   3500 C  CD  . GLU D 1 49  ? -19.632 6.412   -23.769 1.00 83.74  ? 49  GLU F CD  1 
ATOM   3501 O  OE1 . GLU D 1 49  ? -20.233 7.507   -23.855 1.00 71.24  ? 49  GLU F OE1 1 
ATOM   3502 O  OE2 . GLU D 1 49  ? -18.483 6.297   -23.285 1.00 79.56  ? 49  GLU F OE2 1 
ATOM   3503 N  N   . PHE D 1 50  ? -23.401 3.186   -22.502 1.00 54.41  ? 50  PHE F N   1 
ATOM   3504 C  CA  . PHE D 1 50  ? -23.364 2.514   -21.200 1.00 52.58  ? 50  PHE F CA  1 
ATOM   3505 C  C   . PHE D 1 50  ? -24.384 1.396   -21.028 1.00 52.47  ? 50  PHE F C   1 
ATOM   3506 O  O   . PHE D 1 50  ? -25.525 1.529   -21.467 1.00 51.52  ? 50  PHE F O   1 
ATOM   3507 C  CB  . PHE D 1 50  ? -23.479 3.538   -20.041 1.00 56.25  ? 50  PHE F CB  1 
ATOM   3508 C  CG  . PHE D 1 50  ? -22.585 4.753   -20.180 1.00 60.02  ? 50  PHE F CG  1 
ATOM   3509 C  CD1 . PHE D 1 50  ? -21.198 4.621   -20.191 1.00 63.74  ? 50  PHE F CD1 1 
ATOM   3510 C  CD2 . PHE D 1 50  ? -23.128 6.022   -20.339 1.00 64.02  ? 50  PHE F CD2 1 
ATOM   3511 C  CE1 . PHE D 1 50  ? -20.374 5.737   -20.366 1.00 67.13  ? 50  PHE F CE1 1 
ATOM   3512 C  CE2 . PHE D 1 50  ? -22.303 7.138   -20.508 1.00 69.48  ? 50  PHE F CE2 1 
ATOM   3513 C  CZ  . PHE D 1 50  ? -20.932 6.987   -20.524 1.00 68.32  ? 50  PHE F CZ  1 
ATOM   3514 N  N   . GLY D 1 51  ? -23.959 0.322   -20.354 1.00 46.52  ? 51  GLY F N   1 
ATOM   3515 C  CA  . GLY D 1 51  ? -24.800 -0.814  -19.979 1.00 44.63  ? 51  GLY F CA  1 
ATOM   3516 C  C   . GLY D 1 51  ? -25.420 -0.547  -18.621 1.00 49.63  ? 51  GLY F C   1 
ATOM   3517 O  O   . GLY D 1 51  ? -25.353 -1.380  -17.704 1.00 47.01  ? 51  GLY F O   1 
ATOM   3518 N  N   . ASP D 1 52  ? -25.988 0.664   -18.489 1.00 48.65  ? 52  ASP F N   1 
ATOM   3519 C  CA  . ASP D 1 52  ? -26.575 1.209   -17.271 1.00 49.82  ? 52  ASP F CA  1 
ATOM   3520 C  C   . ASP D 1 52  ? -28.087 1.379   -17.455 1.00 55.15  ? 52  ASP F C   1 
ATOM   3521 O  O   . ASP D 1 52  ? -28.531 2.225   -18.223 1.00 55.75  ? 52  ASP F O   1 
ATOM   3522 C  CB  . ASP D 1 52  ? -25.876 2.549   -16.928 1.00 52.81  ? 52  ASP F CB  1 
ATOM   3523 C  CG  . ASP D 1 52  ? -26.196 3.151   -15.570 1.00 60.93  ? 52  ASP F CG  1 
ATOM   3524 O  OD1 . ASP D 1 52  ? -27.330 2.976   -15.095 1.00 60.33  ? 52  ASP F OD1 1 
ATOM   3525 O  OD2 . ASP D 1 52  ? -25.317 3.825   -15.000 1.00 67.87  ? 52  ASP F OD2 1 
ATOM   3526 N  N   . ASN D 1 53  ? -28.863 0.563   -16.736 1.00 52.48  ? 53  ASN F N   1 
ATOM   3527 C  CA  . ASN D 1 53  ? -30.320 0.571   -16.755 1.00 52.75  ? 53  ASN F CA  1 
ATOM   3528 C  C   . ASN D 1 53  ? -30.890 1.014   -15.379 1.00 57.92  ? 53  ASN F C   1 
ATOM   3529 O  O   . ASN D 1 53  ? -32.056 0.747   -15.078 1.00 57.84  ? 53  ASN F O   1 
ATOM   3530 C  CB  . ASN D 1 53  ? -30.825 -0.825  -17.167 1.00 54.11  ? 53  ASN F CB  1 
ATOM   3531 C  CG  . ASN D 1 53  ? -32.319 -0.920  -17.378 1.00 83.82  ? 53  ASN F CG  1 
ATOM   3532 O  OD1 . ASN D 1 53  ? -32.884 -0.357  -18.325 1.00 77.94  ? 53  ASN F OD1 1 
ATOM   3533 N  ND2 . ASN D 1 53  ? -32.994 -1.624  -16.476 1.00 78.57  ? 53  ASN F ND2 1 
ATOM   3534 N  N   . THR D 1 54  ? -30.067 1.699   -14.548 1.00 55.95  ? 54  THR F N   1 
ATOM   3535 C  CA  . THR D 1 54  ? -30.483 2.150   -13.201 1.00 57.83  ? 54  THR F CA  1 
ATOM   3536 C  C   . THR D 1 54  ? -31.665 3.110   -13.227 1.00 64.15  ? 54  THR F C   1 
ATOM   3537 O  O   . THR D 1 54  ? -32.489 3.056   -12.319 1.00 65.71  ? 54  THR F O   1 
ATOM   3538 C  CB  . THR D 1 54  ? -29.320 2.728   -12.387 1.00 64.62  ? 54  THR F CB  1 
ATOM   3539 O  OG1 . THR D 1 54  ? -28.804 3.885   -13.045 1.00 63.41  ? 54  THR F OG1 1 
ATOM   3540 C  CG2 . THR D 1 54  ? -28.217 1.719   -12.142 1.00 61.61  ? 54  THR F CG2 1 
ATOM   3541 N  N   . ALA D 1 55  ? -31.748 3.975   -14.260 1.00 61.28  ? 55  ALA F N   1 
ATOM   3542 C  CA  . ALA D 1 55  ? -32.836 4.943   -14.445 1.00 63.67  ? 55  ALA F CA  1 
ATOM   3543 C  C   . ALA D 1 55  ? -33.576 4.675   -15.769 1.00 67.33  ? 55  ALA F C   1 
ATOM   3544 O  O   . ALA D 1 55  ? -33.930 5.609   -16.501 1.00 69.36  ? 55  ALA F O   1 
ATOM   3545 C  CB  . ALA D 1 55  ? -32.282 6.362   -14.416 1.00 66.80  ? 55  ALA F CB  1 
ATOM   3546 N  N   . GLY D 1 56  ? -33.800 3.394   -16.058 1.00 60.58  ? 56  GLY F N   1 
ATOM   3547 C  CA  . GLY D 1 56  ? -34.463 2.968   -17.282 1.00 59.31  ? 56  GLY F CA  1 
ATOM   3548 C  C   . GLY D 1 56  ? -33.535 3.030   -18.475 1.00 61.39  ? 56  GLY F C   1 
ATOM   3549 O  O   . GLY D 1 56  ? -32.346 2.722   -18.359 1.00 60.19  ? 56  GLY F O   1 
ATOM   3550 N  N   . CYS D 1 57  ? -34.061 3.446   -19.625 1.00 58.19  ? 57  CYS F N   1 
ATOM   3551 C  CA  . CYS D 1 57  ? -33.267 3.527   -20.847 1.00 57.02  ? 57  CYS F CA  1 
ATOM   3552 C  C   . CYS D 1 57  ? -32.462 4.831   -20.957 1.00 61.10  ? 57  CYS F C   1 
ATOM   3553 O  O   . CYS D 1 57  ? -31.478 4.874   -21.697 1.00 58.90  ? 57  CYS F O   1 
ATOM   3554 C  CB  . CYS D 1 57  ? -34.139 3.273   -22.074 1.00 57.70  ? 57  CYS F CB  1 
ATOM   3555 S  SG  . CYS D 1 57  ? -34.911 1.629   -22.099 1.00 60.34  ? 57  CYS F SG  1 
ATOM   3556 N  N   . THR D 1 58  ? -32.838 5.860   -20.168 1.00 60.24  ? 58  THR F N   1 
ATOM   3557 C  CA  . THR D 1 58  ? -32.177 7.172   -20.120 1.00 62.45  ? 58  THR F CA  1 
ATOM   3558 C  C   . THR D 1 58  ? -30.702 7.059   -19.691 1.00 64.50  ? 58  THR F C   1 
ATOM   3559 O  O   . THR D 1 58  ? -29.847 7.740   -20.258 1.00 64.82  ? 58  THR F O   1 
ATOM   3560 C  CB  . THR D 1 58  ? -32.957 8.129   -19.192 1.00 79.00  ? 58  THR F CB  1 
ATOM   3561 O  OG1 . THR D 1 58  ? -34.359 8.017   -19.454 1.00 85.21  ? 58  THR F OG1 1 
ATOM   3562 C  CG2 . THR D 1 58  ? -32.521 9.585   -19.344 1.00 80.83  ? 58  THR F CG2 1 
ATOM   3563 N  N   . SER D 1 59  ? -30.418 6.183   -18.711 1.00 59.40  ? 59  SER F N   1 
ATOM   3564 C  CA  . SER D 1 59  ? -29.091 5.974   -18.127 1.00 58.69  ? 59  SER F CA  1 
ATOM   3565 C  C   . SER D 1 59  ? -28.080 5.287   -19.072 1.00 60.48  ? 59  SER F C   1 
ATOM   3566 O  O   . SER D 1 59  ? -26.877 5.295   -18.785 1.00 60.17  ? 59  SER F O   1 
ATOM   3567 C  CB  . SER D 1 59  ? -29.202 5.234   -16.795 1.00 62.01  ? 59  SER F CB  1 
ATOM   3568 O  OG  . SER D 1 59  ? -30.034 4.088   -16.881 1.00 68.67  ? 59  SER F OG  1 
ATOM   3569 N  N   . ALA D 1 60  ? -28.554 4.744   -20.213 1.00 55.45  ? 60  ALA F N   1 
ATOM   3570 C  CA  . ALA D 1 60  ? -27.708 4.109   -21.235 1.00 54.05  ? 60  ALA F CA  1 
ATOM   3571 C  C   . ALA D 1 60  ? -26.789 5.117   -21.949 1.00 57.97  ? 60  ALA F C   1 
ATOM   3572 O  O   . ALA D 1 60  ? -25.898 4.708   -22.678 1.00 57.05  ? 60  ALA F O   1 
ATOM   3573 C  CB  . ALA D 1 60  ? -28.566 3.368   -22.247 1.00 53.86  ? 60  ALA F CB  1 
ATOM   3574 N  N   . GLY D 1 61  ? -26.998 6.410   -21.701 1.00 56.71  ? 61  GLY F N   1 
ATOM   3575 C  CA  . GLY D 1 61  ? -26.196 7.497   -22.248 1.00 58.54  ? 61  GLY F CA  1 
ATOM   3576 C  C   . GLY D 1 61  ? -26.407 7.762   -23.728 1.00 62.06  ? 61  GLY F C   1 
ATOM   3577 O  O   . GLY D 1 61  ? -27.469 7.441   -24.267 1.00 60.52  ? 61  GLY F O   1 
ATOM   3578 N  N   . PRO D 1 62  ? -25.407 8.362   -24.418 1.00 60.28  ? 62  PRO F N   1 
ATOM   3579 C  CA  . PRO D 1 62  ? -25.579 8.658   -25.853 1.00 60.83  ? 62  PRO F CA  1 
ATOM   3580 C  C   . PRO D 1 62  ? -25.307 7.448   -26.748 1.00 63.86  ? 62  PRO F C   1 
ATOM   3581 O  O   . PRO D 1 62  ? -24.977 6.379   -26.237 1.00 61.13  ? 62  PRO F O   1 
ATOM   3582 C  CB  . PRO D 1 62  ? -24.558 9.773   -26.090 1.00 65.23  ? 62  PRO F CB  1 
ATOM   3583 C  CG  . PRO D 1 62  ? -23.446 9.445   -25.151 1.00 69.27  ? 62  PRO F CG  1 
ATOM   3584 C  CD  . PRO D 1 62  ? -24.080 8.805   -23.935 1.00 63.17  ? 62  PRO F CD  1 
ATOM   3585 N  N   . HIS D 1 63  ? -25.412 7.625   -28.088 1.00 62.92  ? 63  HIS F N   1 
ATOM   3586 C  CA  . HIS D 1 63  ? -25.124 6.587   -29.088 1.00 61.30  ? 63  HIS F CA  1 
ATOM   3587 C  C   . HIS D 1 63  ? -23.666 6.169   -28.916 1.00 64.13  ? 63  HIS F C   1 
ATOM   3588 O  O   . HIS D 1 63  ? -22.824 7.025   -28.630 1.00 65.72  ? 63  HIS F O   1 
ATOM   3589 C  CB  . HIS D 1 63  ? -25.330 7.138   -30.513 1.00 64.21  ? 63  HIS F CB  1 
ATOM   3590 C  CG  . HIS D 1 63  ? -26.759 7.380   -30.908 1.00 68.65  ? 63  HIS F CG  1 
ATOM   3591 N  ND1 . HIS D 1 63  ? -27.138 7.399   -32.239 1.00 71.48  ? 63  HIS F ND1 1 
ATOM   3592 C  CD2 . HIS D 1 63  ? -27.851 7.624   -30.143 1.00 70.90  ? 63  HIS F CD2 1 
ATOM   3593 C  CE1 . HIS D 1 63  ? -28.438 7.642   -32.240 1.00 71.63  ? 63  HIS F CE1 1 
ATOM   3594 N  NE2 . HIS D 1 63  ? -28.911 7.782   -31.002 1.00 71.72  ? 63  HIS F NE2 1 
ATOM   3595 N  N   . PHE D 1 64  ? -23.373 4.863   -29.032 1.00 58.04  ? 64  PHE F N   1 
ATOM   3596 C  CA  . PHE D 1 64  ? -22.006 4.365   -28.875 1.00 57.63  ? 64  PHE F CA  1 
ATOM   3597 C  C   . PHE D 1 64  ? -21.123 4.855   -30.027 1.00 65.36  ? 64  PHE F C   1 
ATOM   3598 O  O   . PHE D 1 64  ? -21.377 4.540   -31.194 1.00 64.09  ? 64  PHE F O   1 
ATOM   3599 C  CB  . PHE D 1 64  ? -21.966 2.834   -28.688 1.00 56.47  ? 64  PHE F CB  1 
ATOM   3600 C  CG  . PHE D 1 64  ? -20.587 2.214   -28.630 1.00 57.43  ? 64  PHE F CG  1 
ATOM   3601 C  CD1 . PHE D 1 64  ? -19.626 2.692   -27.744 1.00 61.53  ? 64  PHE F CD1 1 
ATOM   3602 C  CD2 . PHE D 1 64  ? -20.263 1.126   -29.430 1.00 57.99  ? 64  PHE F CD2 1 
ATOM   3603 C  CE1 . PHE D 1 64  ? -18.347 2.128   -27.704 1.00 62.94  ? 64  PHE F CE1 1 
ATOM   3604 C  CE2 . PHE D 1 64  ? -18.995 0.545   -29.371 1.00 61.22  ? 64  PHE F CE2 1 
ATOM   3605 C  CZ  . PHE D 1 64  ? -18.045 1.048   -28.505 1.00 60.79  ? 64  PHE F CZ  1 
ATOM   3606 N  N   . ASN D 1 65  ? -20.142 5.705   -29.685 1.00 66.72  ? 65  ASN F N   1 
ATOM   3607 C  CA  . ASN D 1 65  ? -19.216 6.321   -30.632 1.00 70.57  ? 65  ASN F CA  1 
ATOM   3608 C  C   . ASN D 1 65  ? -17.838 6.470   -29.965 1.00 78.57  ? 65  ASN F C   1 
ATOM   3609 O  O   . ASN D 1 65  ? -17.552 7.519   -29.376 1.00 80.95  ? 65  ASN F O   1 
ATOM   3610 C  CB  . ASN D 1 65  ? -19.776 7.679   -31.106 1.00 74.84  ? 65  ASN F CB  1 
ATOM   3611 C  CG  . ASN D 1 65  ? -19.127 8.244   -32.344 1.00 95.18  ? 65  ASN F CG  1 
ATOM   3612 O  OD1 . ASN D 1 65  ? -18.867 7.538   -33.325 1.00 86.26  ? 65  ASN F OD1 1 
ATOM   3613 N  ND2 . ASN D 1 65  ? -18.882 9.545   -32.334 1.00 90.46  ? 65  ASN F ND2 1 
ATOM   3614 N  N   . PRO D 1 66  ? -16.982 5.416   -30.013 1.00 75.81  ? 66  PRO F N   1 
ATOM   3615 C  CA  . PRO D 1 66  ? -15.663 5.503   -29.351 1.00 77.88  ? 66  PRO F CA  1 
ATOM   3616 C  C   . PRO D 1 66  ? -14.689 6.530   -29.938 1.00 86.41  ? 66  PRO F C   1 
ATOM   3617 O  O   . PRO D 1 66  ? -13.806 7.001   -29.214 1.00 88.48  ? 66  PRO F O   1 
ATOM   3618 C  CB  . PRO D 1 66  ? -15.117 4.073   -29.452 1.00 77.78  ? 66  PRO F CB  1 
ATOM   3619 C  CG  . PRO D 1 66  ? -15.815 3.483   -30.620 1.00 80.41  ? 66  PRO F CG  1 
ATOM   3620 C  CD  . PRO D 1 66  ? -17.185 4.090   -30.632 1.00 75.12  ? 66  PRO F CD  1 
ATOM   3621 N  N   . LEU D 1 67  ? -14.848 6.875   -31.236 1.00 84.19  ? 67  LEU F N   1 
ATOM   3622 C  CA  . LEU D 1 67  ? -13.990 7.840   -31.934 1.00 119.15 ? 67  LEU F CA  1 
ATOM   3623 C  C   . LEU D 1 67  ? -14.673 9.201   -32.059 1.00 149.77 ? 67  LEU F C   1 
ATOM   3624 O  O   . LEU D 1 67  ? -13.999 10.224  -32.157 1.00 116.29 ? 67  LEU F O   1 
ATOM   3625 C  CB  . LEU D 1 67  ? -13.593 7.315   -33.327 1.00 119.51 ? 67  LEU F CB  1 
ATOM   3626 C  CG  . LEU D 1 67  ? -12.761 6.028   -33.374 1.00 123.06 ? 67  LEU F CG  1 
ATOM   3627 C  CD1 . LEU D 1 67  ? -12.999 5.278   -34.667 1.00 122.34 ? 67  LEU F CD1 1 
ATOM   3628 C  CD2 . LEU D 1 67  ? -11.278 6.313   -33.191 1.00 128.55 ? 67  LEU F CD2 1 
ATOM   3629 N  N   . ARG D 1 79  ? -21.257 8.150   -39.468 1.00 85.06  ? 79  ARG F N   1 
ATOM   3630 C  CA  . ARG D 1 79  ? -22.142 7.387   -38.583 1.00 81.55  ? 79  ARG F CA  1 
ATOM   3631 C  C   . ARG D 1 79  ? -21.440 6.937   -37.306 1.00 82.53  ? 79  ARG F C   1 
ATOM   3632 O  O   . ARG D 1 79  ? -20.230 6.696   -37.321 1.00 82.28  ? 79  ARG F O   1 
ATOM   3633 C  CB  . ARG D 1 79  ? -22.741 6.159   -39.311 1.00 80.44  ? 79  ARG F CB  1 
ATOM   3634 C  CG  . ARG D 1 79  ? -21.701 5.166   -39.865 1.00 88.82  ? 79  ARG F CG  1 
ATOM   3635 C  CD  . ARG D 1 79  ? -22.239 3.751   -39.988 1.00 91.73  ? 79  ARG F CD  1 
ATOM   3636 N  NE  . ARG D 1 79  ? -22.343 3.073   -38.693 1.00 91.64  ? 79  ARG F NE  1 
ATOM   3637 C  CZ  . ARG D 1 79  ? -22.627 1.783   -38.544 1.00 97.19  ? 79  ARG F CZ  1 
ATOM   3638 N  NH1 . ARG D 1 79  ? -22.832 1.012   -39.607 1.00 80.64  ? 79  ARG F NH1 1 
ATOM   3639 N  NH2 . ARG D 1 79  ? -22.709 1.251   -37.331 1.00 75.11  ? 79  ARG F NH2 1 
ATOM   3640 N  N   . HIS D 1 80  ? -22.208 6.785   -36.209 1.00 76.97  ? 80  HIS F N   1 
ATOM   3641 C  CA  . HIS D 1 80  ? -21.678 6.280   -34.941 1.00 74.72  ? 80  HIS F CA  1 
ATOM   3642 C  C   . HIS D 1 80  ? -21.541 4.757   -35.073 1.00 71.82  ? 80  HIS F C   1 
ATOM   3643 O  O   . HIS D 1 80  ? -22.266 4.146   -35.859 1.00 69.35  ? 80  HIS F O   1 
ATOM   3644 C  CB  . HIS D 1 80  ? -22.624 6.611   -33.761 1.00 75.67  ? 80  HIS F CB  1 
ATOM   3645 C  CG  . HIS D 1 80  ? -23.026 8.053   -33.653 1.00 82.64  ? 80  HIS F CG  1 
ATOM   3646 N  ND1 . HIS D 1 80  ? -24.357 8.437   -33.714 1.00 85.17  ? 80  HIS F ND1 1 
ATOM   3647 C  CD2 . HIS D 1 80  ? -22.261 9.157   -33.479 1.00 87.78  ? 80  HIS F CD2 1 
ATOM   3648 C  CE1 . HIS D 1 80  ? -24.357 9.754   -33.585 1.00 87.81  ? 80  HIS F CE1 1 
ATOM   3649 N  NE2 . HIS D 1 80  ? -23.120 10.233  -33.443 1.00 89.81  ? 80  HIS F NE2 1 
ATOM   3650 N  N   . VAL D 1 81  ? -20.629 4.147   -34.301 1.00 66.46  ? 81  VAL F N   1 
ATOM   3651 C  CA  . VAL D 1 81  ? -20.430 2.688   -34.276 1.00 63.82  ? 81  VAL F CA  1 
ATOM   3652 C  C   . VAL D 1 81  ? -21.765 1.983   -33.905 1.00 65.47  ? 81  VAL F C   1 
ATOM   3653 O  O   . VAL D 1 81  ? -22.168 1.036   -34.582 1.00 64.82  ? 81  VAL F O   1 
ATOM   3654 C  CB  . VAL D 1 81  ? -19.239 2.285   -33.354 1.00 66.85  ? 81  VAL F CB  1 
ATOM   3655 C  CG1 . VAL D 1 81  ? -19.198 0.778   -33.101 1.00 64.33  ? 81  VAL F CG1 1 
ATOM   3656 C  CG2 . VAL D 1 81  ? -17.912 2.765   -33.940 1.00 69.03  ? 81  VAL F CG2 1 
ATOM   3657 N  N   . GLY D 1 82  ? -22.466 2.516   -32.906 1.00 60.39  ? 82  GLY F N   1 
ATOM   3658 C  CA  . GLY D 1 82  ? -23.751 1.989   -32.462 1.00 58.33  ? 82  GLY F CA  1 
ATOM   3659 C  C   . GLY D 1 82  ? -24.933 2.101   -33.419 1.00 61.22  ? 82  GLY F C   1 
ATOM   3660 O  O   . GLY D 1 82  ? -25.967 1.477   -33.167 1.00 58.52  ? 82  GLY F O   1 
ATOM   3661 N  N   . ASP D 1 83  ? -24.802 2.879   -34.524 1.00 59.64  ? 83  ASP F N   1 
ATOM   3662 C  CA  . ASP D 1 83  ? -25.879 3.116   -35.503 1.00 60.40  ? 83  ASP F CA  1 
ATOM   3663 C  C   . ASP D 1 83  ? -26.260 1.880   -36.340 1.00 61.14  ? 83  ASP F C   1 
ATOM   3664 O  O   . ASP D 1 83  ? -25.630 1.610   -37.367 1.00 61.00  ? 83  ASP F O   1 
ATOM   3665 C  CB  . ASP D 1 83  ? -25.539 4.314   -36.419 1.00 65.61  ? 83  ASP F CB  1 
ATOM   3666 C  CG  . ASP D 1 83  ? -25.713 5.701   -35.811 1.00 82.44  ? 83  ASP F CG  1 
ATOM   3667 O  OD1 . ASP D 1 83  ? -25.841 5.799   -34.564 1.00 82.48  ? 83  ASP F OD1 1 
ATOM   3668 O  OD2 . ASP D 1 83  ? -25.713 6.691   -36.583 1.00 92.58  ? 83  ASP F OD2 1 
ATOM   3669 N  N   . LEU D 1 84  ? -27.306 1.148   -35.914 1.00 54.51  ? 84  LEU F N   1 
ATOM   3670 C  CA  . LEU D 1 84  ? -27.758 -0.044  -36.635 1.00 54.21  ? 84  LEU F CA  1 
ATOM   3671 C  C   . LEU D 1 84  ? -29.012 0.224   -37.489 1.00 59.98  ? 84  LEU F C   1 
ATOM   3672 O  O   . LEU D 1 84  ? -29.784 -0.700  -37.751 1.00 59.73  ? 84  LEU F O   1 
ATOM   3673 C  CB  . LEU D 1 84  ? -27.980 -1.233  -35.675 1.00 52.86  ? 84  LEU F CB  1 
ATOM   3674 C  CG  . LEU D 1 84  ? -26.764 -1.784  -34.910 1.00 57.10  ? 84  LEU F CG  1 
ATOM   3675 C  CD1 . LEU D 1 84  ? -27.213 -2.666  -33.781 1.00 56.27  ? 84  LEU F CD1 1 
ATOM   3676 C  CD2 . LEU D 1 84  ? -25.826 -2.572  -35.832 1.00 60.67  ? 84  LEU F CD2 1 
ATOM   3677 N  N   . GLY D 1 85  ? -29.179 1.479   -37.921 1.00 57.66  ? 85  GLY F N   1 
ATOM   3678 C  CA  . GLY D 1 85  ? -30.305 1.943   -38.730 1.00 59.09  ? 85  GLY F CA  1 
ATOM   3679 C  C   . GLY D 1 85  ? -31.638 1.935   -38.003 1.00 62.64  ? 85  GLY F C   1 
ATOM   3680 O  O   . GLY D 1 85  ? -31.766 2.477   -36.898 1.00 61.53  ? 85  GLY F O   1 
ATOM   3681 N  N   . ASN D 1 86  ? -32.641 1.315   -38.635 1.00 58.84  ? 86  ASN F N   1 
ATOM   3682 C  CA  . ASN D 1 86  ? -33.999 1.191   -38.112 1.00 58.75  ? 86  ASN F CA  1 
ATOM   3683 C  C   . ASN D 1 86  ? -34.442 -0.259  -38.109 1.00 62.11  ? 86  ASN F C   1 
ATOM   3684 O  O   . ASN D 1 86  ? -33.910 -1.074  -38.863 1.00 62.11  ? 86  ASN F O   1 
ATOM   3685 C  CB  . ASN D 1 86  ? -35.005 1.972   -39.010 1.00 58.67  ? 86  ASN F CB  1 
ATOM   3686 C  CG  . ASN D 1 86  ? -34.895 3.472   -38.967 1.00 71.95  ? 86  ASN F CG  1 
ATOM   3687 O  OD1 . ASN D 1 86  ? -35.088 4.098   -37.923 1.00 60.12  ? 86  ASN F OD1 1 
ATOM   3688 N  ND2 . ASN D 1 86  ? -34.612 4.086   -40.115 1.00 66.52  ? 86  ASN F ND2 1 
ATOM   3689 N  N   . VAL D 1 87  ? -35.448 -0.564  -37.283 1.00 57.92  ? 87  VAL F N   1 
ATOM   3690 C  CA  . VAL D 1 87  ? -36.180 -1.828  -37.276 1.00 58.06  ? 87  VAL F CA  1 
ATOM   3691 C  C   . VAL D 1 87  ? -37.591 -1.517  -37.792 1.00 63.21  ? 87  VAL F C   1 
ATOM   3692 O  O   . VAL D 1 87  ? -38.081 -0.401  -37.602 1.00 63.48  ? 87  VAL F O   1 
ATOM   3693 C  CB  . VAL D 1 87  ? -36.167 -2.634  -35.955 1.00 60.48  ? 87  VAL F CB  1 
ATOM   3694 C  CG1 . VAL D 1 87  ? -34.771 -3.191  -35.680 1.00 58.23  ? 87  VAL F CG1 1 
ATOM   3695 C  CG2 . VAL D 1 87  ? -36.690 -1.814  -34.777 1.00 60.33  ? 87  VAL F CG2 1 
ATOM   3696 N  N   . THR D 1 88  ? -38.222 -2.466  -38.470 1.00 61.58  ? 88  THR F N   1 
ATOM   3697 C  CA  . THR D 1 88  ? -39.541 -2.218  -39.062 1.00 64.76  ? 88  THR F CA  1 
ATOM   3698 C  C   . THR D 1 88  ? -40.586 -3.190  -38.536 1.00 70.16  ? 88  THR F C   1 
ATOM   3699 O  O   . THR D 1 88  ? -40.474 -4.404  -38.712 1.00 70.18  ? 88  THR F O   1 
ATOM   3700 C  CB  . THR D 1 88  ? -39.471 -2.150  -40.596 1.00 72.75  ? 88  THR F CB  1 
ATOM   3701 O  OG1 . THR D 1 88  ? -40.805 -2.095  -41.138 1.00 79.84  ? 88  THR F OG1 1 
ATOM   3702 C  CG2 . THR D 1 88  ? -38.697 -3.306  -41.207 1.00 67.52  ? 88  THR F CG2 1 
ATOM   3703 N  N   . ALA D 1 89  ? -41.613 -2.625  -37.896 1.00 67.91  ? 89  ALA F N   1 
ATOM   3704 C  CA  . ALA D 1 89  ? -42.711 -3.363  -37.301 1.00 68.97  ? 89  ALA F CA  1 
ATOM   3705 C  C   . ALA D 1 89  ? -43.840 -3.540  -38.305 1.00 77.29  ? 89  ALA F C   1 
ATOM   3706 O  O   . ALA D 1 89  ? -44.176 -2.602  -39.041 1.00 78.08  ? 89  ALA F O   1 
ATOM   3707 C  CB  . ALA D 1 89  ? -43.212 -2.627  -36.072 1.00 69.57  ? 89  ALA F CB  1 
ATOM   3708 N  N   . ASP D 1 90  ? -44.420 -4.753  -38.342 1.00 76.03  ? 90  ASP F N   1 
ATOM   3709 C  CA  . ASP D 1 90  ? -45.543 -5.070  -39.223 1.00 79.46  ? 90  ASP F CA  1 
ATOM   3710 C  C   . ASP D 1 90  ? -46.837 -4.514  -38.596 1.00 85.45  ? 90  ASP F C   1 
ATOM   3711 O  O   . ASP D 1 90  ? -46.775 -3.870  -37.537 1.00 82.34  ? 90  ASP F O   1 
ATOM   3712 C  CB  . ASP D 1 90  ? -45.624 -6.596  -39.505 1.00 81.88  ? 90  ASP F CB  1 
ATOM   3713 C  CG  . ASP D 1 90  ? -46.033 -7.516  -38.352 1.00 85.80  ? 90  ASP F CG  1 
ATOM   3714 O  OD1 . ASP D 1 90  ? -46.487 -7.006  -37.312 1.00 84.25  ? 90  ASP F OD1 1 
ATOM   3715 O  OD2 . ASP D 1 90  ? -45.921 -8.748  -38.507 1.00 92.80  ? 90  ASP F OD2 1 
ATOM   3716 N  N   . LYS D 1 91  ? -47.998 -4.791  -39.231 1.00 85.71  ? 91  LYS F N   1 
ATOM   3717 C  CA  . LYS D 1 91  ? -49.330 -4.366  -38.789 1.00 89.48  ? 91  LYS F CA  1 
ATOM   3718 C  C   . LYS D 1 91  ? -49.740 -4.916  -37.404 1.00 94.20  ? 91  LYS F C   1 
ATOM   3719 O  O   . LYS D 1 91  ? -50.631 -4.345  -36.769 1.00 96.32  ? 91  LYS F O   1 
ATOM   3720 C  CB  . LYS D 1 91  ? -50.395 -4.700  -39.863 1.00 96.41  ? 91  LYS F CB  1 
ATOM   3721 C  CG  . LYS D 1 91  ? -50.605 -6.195  -40.110 1.00 113.74 ? 91  LYS F CG  1 
ATOM   3722 C  CD  . LYS D 1 91  ? -51.167 -6.487  -41.493 1.00 130.82 ? 91  LYS F CD  1 
ATOM   3723 C  CE  . LYS D 1 91  ? -51.361 -7.970  -41.698 1.00 146.02 ? 91  LYS F CE  1 
ATOM   3724 N  NZ  . LYS D 1 91  ? -51.382 -8.337  -43.139 1.00 158.28 ? 91  LYS F NZ  1 
ATOM   3725 N  N   . ASP D 1 92  ? -49.116 -6.029  -36.960 1.00 88.94  ? 92  ASP F N   1 
ATOM   3726 C  CA  . ASP D 1 92  ? -49.376 -6.648  -35.651 1.00 88.60  ? 92  ASP F CA  1 
ATOM   3727 C  C   . ASP D 1 92  ? -48.364 -6.133  -34.611 1.00 86.43  ? 92  ASP F C   1 
ATOM   3728 O  O   . ASP D 1 92  ? -48.388 -6.560  -33.453 1.00 84.71  ? 92  ASP F O   1 
ATOM   3729 C  CB  . ASP D 1 92  ? -49.305 -8.189  -35.739 1.00 91.74  ? 92  ASP F CB  1 
ATOM   3730 C  CG  . ASP D 1 92  ? -50.181 -8.842  -36.792 1.00 107.49 ? 92  ASP F CG  1 
ATOM   3731 O  OD1 . ASP D 1 92  ? -51.374 -8.472  -36.887 1.00 112.62 ? 92  ASP F OD1 1 
ATOM   3732 O  OD2 . ASP D 1 92  ? -49.682 -9.740  -37.504 1.00 112.93 ? 92  ASP F OD2 1 
ATOM   3733 N  N   . GLY D 1 93  ? -47.488 -5.227  -35.040 1.00 79.68  ? 93  GLY F N   1 
ATOM   3734 C  CA  . GLY D 1 93  ? -46.466 -4.631  -34.188 1.00 75.39  ? 93  GLY F CA  1 
ATOM   3735 C  C   . GLY D 1 93  ? -45.234 -5.485  -33.975 1.00 74.73  ? 93  GLY F C   1 
ATOM   3736 O  O   . GLY D 1 93  ? -44.474 -5.245  -33.035 1.00 71.52  ? 93  GLY F O   1 
ATOM   3737 N  N   . VAL D 1 94  ? -45.022 -6.474  -34.851 1.00 72.02  ? 94  VAL F N   1 
ATOM   3738 C  CA  . VAL D 1 94  ? -43.875 -7.368  -34.775 1.00 69.38  ? 94  VAL F CA  1 
ATOM   3739 C  C   . VAL D 1 94  ? -42.800 -6.952  -35.783 1.00 73.15  ? 94  VAL F C   1 
ATOM   3740 O  O   . VAL D 1 94  ? -43.046 -6.914  -37.002 1.00 74.32  ? 94  VAL F O   1 
ATOM   3741 C  CB  . VAL D 1 94  ? -44.256 -8.873  -34.869 1.00 74.52  ? 94  VAL F CB  1 
ATOM   3742 C  CG1 . VAL D 1 94  ? -43.023 -9.768  -34.714 1.00 71.55  ? 94  VAL F CG1 1 
ATOM   3743 C  CG2 . VAL D 1 94  ? -45.310 -9.239  -33.825 1.00 75.92  ? 94  VAL F CG2 1 
ATOM   3744 N  N   . ALA D 1 95  ? -41.622 -6.609  -35.250 1.00 67.27  ? 95  ALA F N   1 
ATOM   3745 C  CA  . ALA D 1 95  ? -40.444 -6.227  -36.021 1.00 66.40  ? 95  ALA F CA  1 
ATOM   3746 C  C   . ALA D 1 95  ? -39.471 -7.385  -36.050 1.00 71.04  ? 95  ALA F C   1 
ATOM   3747 O  O   . ALA D 1 95  ? -38.882 -7.721  -35.019 1.00 69.33  ? 95  ALA F O   1 
ATOM   3748 C  CB  . ALA D 1 95  ? -39.781 -4.992  -35.420 1.00 64.64  ? 95  ALA F CB  1 
ATOM   3749 N  N   . ASP D 1 96  ? -39.363 -8.047  -37.205 1.00 71.54  ? 96  ASP F N   1 
ATOM   3750 C  CA  . ASP D 1 96  ? -38.402 -9.132  -37.373 1.00 71.95  ? 96  ASP F CA  1 
ATOM   3751 C  C   . ASP D 1 96  ? -37.082 -8.522  -37.843 1.00 71.66  ? 96  ASP F C   1 
ATOM   3752 O  O   . ASP D 1 96  ? -37.037 -7.778  -38.833 1.00 71.04  ? 96  ASP F O   1 
ATOM   3753 C  CB  . ASP D 1 96  ? -38.905 -10.241 -38.313 1.00 78.22  ? 96  ASP F CB  1 
ATOM   3754 C  CG  . ASP D 1 96  ? -38.409 -11.605 -37.856 1.00 96.56  ? 96  ASP F CG  1 
ATOM   3755 O  OD1 . ASP D 1 96  ? -38.931 -12.119 -36.832 1.00 97.68  ? 96  ASP F OD1 1 
ATOM   3756 O  OD2 . ASP D 1 96  ? -37.480 -12.146 -38.499 1.00 104.38 ? 96  ASP F OD2 1 
ATOM   3757 N  N   . VAL D 1 97  ? -36.025 -8.776  -37.078 1.00 64.42  ? 97  VAL F N   1 
ATOM   3758 C  CA  . VAL D 1 97  ? -34.715 -8.189  -37.335 1.00 61.74  ? 97  VAL F CA  1 
ATOM   3759 C  C   . VAL D 1 97  ? -33.757 -9.157  -38.009 1.00 63.56  ? 97  VAL F C   1 
ATOM   3760 O  O   . VAL D 1 97  ? -33.686 -10.321 -37.624 1.00 62.87  ? 97  VAL F O   1 
ATOM   3761 C  CB  . VAL D 1 97  ? -34.113 -7.582  -36.034 1.00 62.75  ? 97  VAL F CB  1 
ATOM   3762 C  CG1 . VAL D 1 97  ? -32.891 -6.718  -36.336 1.00 60.81  ? 97  VAL F CG1 1 
ATOM   3763 C  CG2 . VAL D 1 97  ? -35.160 -6.773  -35.277 1.00 62.72  ? 97  VAL F CG2 1 
ATOM   3764 N  N   . SER D 1 98  ? -33.030 -8.656  -39.026 1.00 59.90  ? 98  SER F N   1 
ATOM   3765 C  CA  . SER D 1 98  ? -31.961 -9.343  -39.748 1.00 60.15  ? 98  SER F CA  1 
ATOM   3766 C  C   . SER D 1 98  ? -31.018 -8.279  -40.316 1.00 64.41  ? 98  SER F C   1 
ATOM   3767 O  O   . SER D 1 98  ? -31.329 -7.649  -41.330 1.00 64.90  ? 98  SER F O   1 
ATOM   3768 C  CB  . SER D 1 98  ? -32.509 -10.242 -40.854 1.00 66.24  ? 98  SER F CB  1 
ATOM   3769 O  OG  . SER D 1 98  ? -31.485 -11.127 -41.277 1.00 72.90  ? 98  SER F OG  1 
ATOM   3770 N  N   . ILE D 1 99  ? -29.901 -8.029  -39.610 1.00 59.77  ? 99  ILE F N   1 
ATOM   3771 C  CA  . ILE D 1 99  ? -28.891 -7.025  -39.964 1.00 59.19  ? 99  ILE F CA  1 
ATOM   3772 C  C   . ILE D 1 99  ? -27.491 -7.656  -39.977 1.00 63.41  ? 99  ILE F C   1 
ATOM   3773 O  O   . ILE D 1 99  ? -27.188 -8.514  -39.150 1.00 62.40  ? 99  ILE F O   1 
ATOM   3774 C  CB  . ILE D 1 99  ? -28.943 -5.797  -38.980 1.00 60.16  ? 99  ILE F CB  1 
ATOM   3775 C  CG1 . ILE D 1 99  ? -30.305 -5.083  -39.009 1.00 60.68  ? 99  ILE F CG1 1 
ATOM   3776 C  CG2 . ILE D 1 99  ? -27.791 -4.787  -39.226 1.00 60.99  ? 99  ILE F CG2 1 
ATOM   3777 C  CD1 . ILE D 1 99  ? -30.624 -4.165  -37.782 1.00 59.92  ? 99  ILE F CD1 1 
ATOM   3778 N  N   . GLU D 1 100 ? -26.646 -7.214  -40.919 1.00 61.65  ? 100 GLU F N   1 
ATOM   3779 C  CA  . GLU D 1 100 ? -25.233 -7.573  -41.013 1.00 61.36  ? 100 GLU F CA  1 
ATOM   3780 C  C   . GLU D 1 100 ? -24.497 -6.240  -40.895 1.00 63.68  ? 100 GLU F C   1 
ATOM   3781 O  O   . GLU D 1 100 ? -24.823 -5.295  -41.622 1.00 64.09  ? 100 GLU F O   1 
ATOM   3782 C  CB  . GLU D 1 100 ? -24.904 -8.280  -42.341 1.00 64.93  ? 100 GLU F CB  1 
ATOM   3783 C  CG  . GLU D 1 100 ? -23.652 -9.138  -42.246 1.00 76.32  ? 100 GLU F CG  1 
ATOM   3784 C  CD  . GLU D 1 100 ? -23.131 -9.719  -43.546 1.00 105.60 ? 100 GLU F CD  1 
ATOM   3785 O  OE1 . GLU D 1 100 ? -23.829 -10.573 -44.142 1.00 107.52 ? 100 GLU F OE1 1 
ATOM   3786 O  OE2 . GLU D 1 100 ? -22.012 -9.336  -43.959 1.00 96.43  ? 100 GLU F OE2 1 
ATOM   3787 N  N   . ASP D 1 101 ? -23.569 -6.135  -39.935 1.00 58.91  ? 101 ASP F N   1 
ATOM   3788 C  CA  . ASP D 1 101 ? -22.812 -4.905  -39.697 1.00 58.50  ? 101 ASP F CA  1 
ATOM   3789 C  C   . ASP D 1 101 ? -21.313 -5.167  -39.528 1.00 61.93  ? 101 ASP F C   1 
ATOM   3790 O  O   . ASP D 1 101 ? -20.917 -6.067  -38.784 1.00 60.64  ? 101 ASP F O   1 
ATOM   3791 C  CB  . ASP D 1 101 ? -23.373 -4.135  -38.484 1.00 58.49  ? 101 ASP F CB  1 
ATOM   3792 C  CG  . ASP D 1 101 ? -22.996 -2.667  -38.480 1.00 70.19  ? 101 ASP F CG  1 
ATOM   3793 O  OD1 . ASP D 1 101 ? -23.535 -1.912  -39.321 1.00 72.43  ? 101 ASP F OD1 1 
ATOM   3794 O  OD2 . ASP D 1 101 ? -22.149 -2.275  -37.649 1.00 76.27  ? 101 ASP F OD2 1 
ATOM   3795 N  N   . SER D 1 102 ? -20.491 -4.341  -40.182 1.00 59.59  ? 102 SER F N   1 
ATOM   3796 C  CA  . SER D 1 102 ? -19.030 -4.445  -40.169 1.00 60.96  ? 102 SER F CA  1 
ATOM   3797 C  C   . SER D 1 102 ? -18.330 -3.428  -39.251 1.00 67.29  ? 102 SER F C   1 
ATOM   3798 O  O   . SER D 1 102 ? -17.109 -3.505  -39.064 1.00 68.67  ? 102 SER F O   1 
ATOM   3799 C  CB  . SER D 1 102 ? -18.488 -4.357  -41.593 1.00 66.63  ? 102 SER F CB  1 
ATOM   3800 O  OG  . SER D 1 102 ? -18.886 -5.493  -42.341 1.00 75.38  ? 102 SER F OG  1 
ATOM   3801 N  N   . VAL D 1 103 ? -19.100 -2.495  -38.659 1.00 63.17  ? 103 VAL F N   1 
ATOM   3802 C  CA  . VAL D 1 103 ? -18.559 -1.455  -37.780 1.00 62.70  ? 103 VAL F CA  1 
ATOM   3803 C  C   . VAL D 1 103 ? -18.569 -1.942  -36.318 1.00 62.65  ? 103 VAL F C   1 
ATOM   3804 O  O   . VAL D 1 103 ? -17.562 -1.788  -35.626 1.00 62.26  ? 103 VAL F O   1 
ATOM   3805 C  CB  . VAL D 1 103 ? -19.250 -0.079  -38.009 1.00 67.95  ? 103 VAL F CB  1 
ATOM   3806 C  CG1 . VAL D 1 103 ? -18.613 1.012   -37.158 1.00 68.70  ? 103 VAL F CG1 1 
ATOM   3807 C  CG2 . VAL D 1 103 ? -19.179 0.318   -39.487 1.00 70.16  ? 103 VAL F CG2 1 
ATOM   3808 N  N   . ILE D 1 104 ? -19.668 -2.581  -35.878 1.00 56.07  ? 104 ILE F N   1 
ATOM   3809 C  CA  . ILE D 1 104 ? -19.766 -3.153  -34.529 1.00 53.86  ? 104 ILE F CA  1 
ATOM   3810 C  C   . ILE D 1 104 ? -18.908 -4.424  -34.437 1.00 55.86  ? 104 ILE F C   1 
ATOM   3811 O  O   . ILE D 1 104 ? -18.610 -5.038  -35.462 1.00 55.43  ? 104 ILE F O   1 
ATOM   3812 C  CB  . ILE D 1 104 ? -21.227 -3.412  -34.045 1.00 55.38  ? 104 ILE F CB  1 
ATOM   3813 C  CG1 . ILE D 1 104 ? -21.989 -4.398  -34.975 1.00 55.92  ? 104 ILE F CG1 1 
ATOM   3814 C  CG2 . ILE D 1 104 ? -21.997 -2.105  -33.826 1.00 55.24  ? 104 ILE F CG2 1 
ATOM   3815 C  CD1 . ILE D 1 104 ? -23.236 -5.114  -34.309 1.00 57.13  ? 104 ILE F CD1 1 
ATOM   3816 N  N   . SER D 1 105 ? -18.526 -4.812  -33.208 1.00 49.54  ? 105 SER F N   1 
ATOM   3817 C  CA  . SER D 1 105 ? -17.759 -6.026  -32.960 1.00 48.94  ? 105 SER F CA  1 
ATOM   3818 C  C   . SER D 1 105 ? -18.154 -6.647  -31.624 1.00 52.89  ? 105 SER F C   1 
ATOM   3819 O  O   . SER D 1 105 ? -18.679 -5.949  -30.764 1.00 52.26  ? 105 SER F O   1 
ATOM   3820 C  CB  . SER D 1 105 ? -16.261 -5.730  -32.983 1.00 50.47  ? 105 SER F CB  1 
ATOM   3821 O  OG  . SER D 1 105 ? -15.550 -6.954  -33.014 1.00 53.49  ? 105 SER F OG  1 
ATOM   3822 N  N   . LEU D 1 106 ? -17.895 -7.951  -31.444 1.00 50.25  ? 106 LEU F N   1 
ATOM   3823 C  CA  . LEU D 1 106 ? -18.142 -8.621  -30.165 1.00 49.16  ? 106 LEU F CA  1 
ATOM   3824 C  C   . LEU D 1 106 ? -16.830 -8.775  -29.352 1.00 55.25  ? 106 LEU F C   1 
ATOM   3825 O  O   . LEU D 1 106 ? -16.819 -9.473  -28.342 1.00 54.20  ? 106 LEU F O   1 
ATOM   3826 C  CB  . LEU D 1 106 ? -18.925 -9.952  -30.309 1.00 49.23  ? 106 LEU F CB  1 
ATOM   3827 C  CG  . LEU D 1 106 ? -20.317 -9.916  -31.012 1.00 52.84  ? 106 LEU F CG  1 
ATOM   3828 C  CD1 . LEU D 1 106 ? -20.967 -11.283 -31.013 1.00 53.66  ? 106 LEU F CD1 1 
ATOM   3829 C  CD2 . LEU D 1 106 ? -21.274 -8.922  -30.370 1.00 51.41  ? 106 LEU F CD2 1 
ATOM   3830 N  N   . SER D 1 107 ? -15.745 -8.068  -29.776 1.00 54.26  ? 107 SER F N   1 
ATOM   3831 C  CA  . SER D 1 107 ? -14.419 -8.003  -29.116 1.00 56.09  ? 107 SER F CA  1 
ATOM   3832 C  C   . SER D 1 107 ? -13.640 -6.728  -29.526 1.00 61.69  ? 107 SER F C   1 
ATOM   3833 O  O   . SER D 1 107 ? -14.041 -6.044  -30.461 1.00 59.34  ? 107 SER F O   1 
ATOM   3834 C  CB  . SER D 1 107 ? -13.594 -9.256  -29.414 1.00 61.82  ? 107 SER F CB  1 
ATOM   3835 O  OG  . SER D 1 107 ? -13.442 -9.474  -30.807 1.00 72.43  ? 107 SER F OG  1 
ATOM   3836 N  N   . GLY D 1 108 ? -12.552 -6.416  -28.810 1.00 62.64  ? 108 GLY F N   1 
ATOM   3837 C  CA  . GLY D 1 108 ? -11.693 -5.266  -29.102 1.00 64.82  ? 108 GLY F CA  1 
ATOM   3838 C  C   . GLY D 1 108 ? -12.292 -3.881  -28.900 1.00 69.54  ? 108 GLY F C   1 
ATOM   3839 O  O   . GLY D 1 108 ? -13.174 -3.697  -28.057 1.00 66.77  ? 108 GLY F O   1 
ATOM   3840 N  N   . ASP D 1 109 ? -11.801 -2.891  -29.688 1.00 68.57  ? 109 ASP F N   1 
ATOM   3841 C  CA  . ASP D 1 109 ? -12.182 -1.469  -29.616 1.00 68.94  ? 109 ASP F CA  1 
ATOM   3842 C  C   . ASP D 1 109 ? -13.667 -1.170  -29.825 1.00 68.32  ? 109 ASP F C   1 
ATOM   3843 O  O   . ASP D 1 109 ? -14.235 -0.363  -29.085 1.00 67.68  ? 109 ASP F O   1 
ATOM   3844 C  CB  . ASP D 1 109 ? -11.342 -0.619  -30.592 1.00 74.36  ? 109 ASP F CB  1 
ATOM   3845 C  CG  . ASP D 1 109 ? -10.215 0.194   -29.960 1.00 92.32  ? 109 ASP F CG  1 
ATOM   3846 O  OD1 . ASP D 1 109 ? -10.301 0.498   -28.743 1.00 94.12  ? 109 ASP F OD1 1 
ATOM   3847 O  OD2 . ASP D 1 109 ? -9.264  0.553   -30.686 1.00 99.84  ? 109 ASP F OD2 1 
ATOM   3848 N  N   . HIS D 1 110 ? -14.288 -1.802  -30.827 1.00 61.98  ? 110 HIS F N   1 
ATOM   3849 C  CA  . HIS D 1 110 ? -15.692 -1.565  -31.163 1.00 59.09  ? 110 HIS F CA  1 
ATOM   3850 C  C   . HIS D 1 110 ? -16.650 -2.553  -30.489 1.00 59.31  ? 110 HIS F C   1 
ATOM   3851 O  O   . HIS D 1 110 ? -17.798 -2.689  -30.927 1.00 57.81  ? 110 HIS F O   1 
ATOM   3852 C  CB  . HIS D 1 110 ? -15.879 -1.543  -32.694 1.00 60.26  ? 110 HIS F CB  1 
ATOM   3853 C  CG  . HIS D 1 110 ? -15.275 -0.351  -33.381 1.00 65.91  ? 110 HIS F CG  1 
ATOM   3854 N  ND1 . HIS D 1 110 ? -15.553 -0.076  -34.706 1.00 68.45  ? 110 HIS F ND1 1 
ATOM   3855 C  CD2 . HIS D 1 110 ? -14.412 0.585   -32.914 1.00 69.77  ? 110 HIS F CD2 1 
ATOM   3856 C  CE1 . HIS D 1 110 ? -14.872 1.019   -34.998 1.00 70.42  ? 110 HIS F CE1 1 
ATOM   3857 N  NE2 . HIS D 1 110 ? -14.167 1.451   -33.951 1.00 71.70  ? 110 HIS F NE2 1 
ATOM   3858 N  N   . CYS D 1 111 ? -16.185 -3.221  -29.415 1.00 55.06  ? 111 CYS F N   1 
ATOM   3859 C  CA  . CYS D 1 111 ? -16.963 -4.204  -28.672 1.00 53.12  ? 111 CYS F CA  1 
ATOM   3860 C  C   . CYS D 1 111 ? -18.230 -3.611  -28.071 1.00 53.62  ? 111 CYS F C   1 
ATOM   3861 O  O   . CYS D 1 111 ? -18.173 -2.602  -27.363 1.00 52.70  ? 111 CYS F O   1 
ATOM   3862 C  CB  . CYS D 1 111 ? -16.117 -4.902  -27.618 1.00 54.24  ? 111 CYS F CB  1 
ATOM   3863 S  SG  . CYS D 1 111 ? -16.966 -6.261  -26.777 1.00 57.11  ? 111 CYS F SG  1 
ATOM   3864 N  N   . ILE D 1 112 ? -19.367 -4.254  -28.353 1.00 48.96  ? 112 ILE F N   1 
ATOM   3865 C  CA  . ILE D 1 112 ? -20.684 -3.814  -27.879 1.00 47.11  ? 112 ILE F CA  1 
ATOM   3866 C  C   . ILE D 1 112 ? -21.156 -4.596  -26.637 1.00 48.81  ? 112 ILE F C   1 
ATOM   3867 O  O   . ILE D 1 112 ? -22.148 -4.212  -26.035 1.00 45.83  ? 112 ILE F O   1 
ATOM   3868 C  CB  . ILE D 1 112 ? -21.732 -3.814  -29.028 1.00 50.03  ? 112 ILE F CB  1 
ATOM   3869 C  CG1 . ILE D 1 112 ? -22.028 -5.253  -29.540 1.00 50.53  ? 112 ILE F CG1 1 
ATOM   3870 C  CG2 . ILE D 1 112 ? -21.266 -2.878  -30.171 1.00 51.01  ? 112 ILE F CG2 1 
ATOM   3871 C  CD1 . ILE D 1 112 ? -23.194 -5.377  -30.482 1.00 54.43  ? 112 ILE F CD1 1 
ATOM   3872 N  N   . ILE D 1 113 ? -20.444 -5.670  -26.251 1.00 47.28  ? 113 ILE F N   1 
ATOM   3873 C  CA  . ILE D 1 113 ? -20.776 -6.456  -25.059 1.00 47.09  ? 113 ILE F CA  1 
ATOM   3874 C  C   . ILE D 1 113 ? -20.626 -5.558  -23.819 1.00 49.83  ? 113 ILE F C   1 
ATOM   3875 O  O   . ILE D 1 113 ? -19.635 -4.835  -23.695 1.00 50.44  ? 113 ILE F O   1 
ATOM   3876 C  CB  . ILE D 1 113 ? -19.939 -7.773  -24.998 1.00 51.44  ? 113 ILE F CB  1 
ATOM   3877 C  CG1 . ILE D 1 113 ? -20.377 -8.736  -26.135 1.00 51.86  ? 113 ILE F CG1 1 
ATOM   3878 C  CG2 . ILE D 1 113 ? -20.037 -8.458  -23.609 1.00 51.73  ? 113 ILE F CG2 1 
ATOM   3879 C  CD1 . ILE D 1 113 ? -19.450 -9.918  -26.393 1.00 64.62  ? 113 ILE F CD1 1 
ATOM   3880 N  N   . GLY D 1 114 ? -21.650 -5.567  -22.967 1.00 44.77  ? 114 GLY F N   1 
ATOM   3881 C  CA  . GLY D 1 114 ? -21.696 -4.750  -21.762 1.00 43.66  ? 114 GLY F CA  1 
ATOM   3882 C  C   . GLY D 1 114 ? -22.323 -3.398  -22.023 1.00 46.00  ? 114 GLY F C   1 
ATOM   3883 O  O   . GLY D 1 114 ? -22.438 -2.584  -21.114 1.00 45.71  ? 114 GLY F O   1 
ATOM   3884 N  N   . ARG D 1 115 ? -22.705 -3.126  -23.273 1.00 42.78  ? 115 ARG F N   1 
ATOM   3885 C  CA  . ARG D 1 115 ? -23.350 -1.862  -23.622 1.00 43.35  ? 115 ARG F CA  1 
ATOM   3886 C  C   . ARG D 1 115 ? -24.855 -2.112  -23.810 1.00 47.18  ? 115 ARG F C   1 
ATOM   3887 O  O   . ARG D 1 115 ? -25.291 -3.255  -23.691 1.00 46.44  ? 115 ARG F O   1 
ATOM   3888 C  CB  . ARG D 1 115 ? -22.667 -1.203  -24.837 1.00 44.55  ? 115 ARG F CB  1 
ATOM   3889 C  CG  . ARG D 1 115 ? -21.168 -1.063  -24.623 1.00 46.82  ? 115 ARG F CG  1 
ATOM   3890 C  CD  . ARG D 1 115 ? -20.471 -0.175  -25.619 1.00 54.72  ? 115 ARG F CD  1 
ATOM   3891 N  NE  . ARG D 1 115 ? -19.010 -0.226  -25.449 1.00 56.01  ? 115 ARG F NE  1 
ATOM   3892 C  CZ  . ARG D 1 115 ? -18.306 0.581   -24.658 1.00 68.79  ? 115 ARG F CZ  1 
ATOM   3893 N  NH1 . ARG D 1 115 ? -18.914 1.519   -23.944 1.00 53.50  ? 115 ARG F NH1 1 
ATOM   3894 N  NH2 . ARG D 1 115 ? -16.990 0.456   -24.577 1.00 62.04  ? 115 ARG F NH2 1 
ATOM   3895 N  N   . THR D 1 116 ? -25.652 -1.060  -24.046 1.00 44.15  ? 116 THR F N   1 
ATOM   3896 C  CA  . THR D 1 116 ? -27.105 -1.201  -24.146 1.00 43.70  ? 116 THR F CA  1 
ATOM   3897 C  C   . THR D 1 116 ? -27.621 -1.050  -25.560 1.00 46.36  ? 116 THR F C   1 
ATOM   3898 O  O   . THR D 1 116 ? -27.276 -0.089  -26.233 1.00 47.55  ? 116 THR F O   1 
ATOM   3899 C  CB  . THR D 1 116 ? -27.805 -0.195  -23.208 1.00 49.44  ? 116 THR F CB  1 
ATOM   3900 O  OG1 . THR D 1 116 ? -27.389 -0.423  -21.874 1.00 47.14  ? 116 THR F OG1 1 
ATOM   3901 C  CG2 . THR D 1 116 ? -29.330 -0.279  -23.262 1.00 50.48  ? 116 THR F CG2 1 
ATOM   3902 N  N   . LEU D 1 117 ? -28.476 -1.978  -25.985 1.00 41.89  ? 117 LEU F N   1 
ATOM   3903 C  CA  . LEU D 1 117 ? -29.178 -1.911  -27.258 1.00 43.00  ? 117 LEU F CA  1 
ATOM   3904 C  C   . LEU D 1 117 ? -30.522 -1.206  -26.983 1.00 48.83  ? 117 LEU F C   1 
ATOM   3905 O  O   . LEU D 1 117 ? -31.190 -1.529  -26.004 1.00 47.34  ? 117 LEU F O   1 
ATOM   3906 C  CB  . LEU D 1 117 ? -29.404 -3.323  -27.814 1.00 43.10  ? 117 LEU F CB  1 
ATOM   3907 C  CG  . LEU D 1 117 ? -30.180 -3.450  -29.125 1.00 48.06  ? 117 LEU F CG  1 
ATOM   3908 C  CD1 . LEU D 1 117 ? -29.392 -2.872  -30.299 1.00 48.65  ? 117 LEU F CD1 1 
ATOM   3909 C  CD2 . LEU D 1 117 ? -30.516 -4.883  -29.383 1.00 48.90  ? 117 LEU F CD2 1 
ATOM   3910 N  N   . VAL D 1 118 ? -30.886 -0.209  -27.808 1.00 47.35  ? 118 VAL F N   1 
ATOM   3911 C  CA  . VAL D 1 118 ? -32.108 0.574   -27.606 1.00 48.77  ? 118 VAL F CA  1 
ATOM   3912 C  C   . VAL D 1 118 ? -32.952 0.685   -28.875 1.00 52.77  ? 118 VAL F C   1 
ATOM   3913 O  O   . VAL D 1 118 ? -32.434 1.021   -29.935 1.00 53.12  ? 118 VAL F O   1 
ATOM   3914 C  CB  . VAL D 1 118 ? -31.821 1.990   -27.003 1.00 54.00  ? 118 VAL F CB  1 
ATOM   3915 C  CG1 . VAL D 1 118 ? -33.116 2.735   -26.672 1.00 55.79  ? 118 VAL F CG1 1 
ATOM   3916 C  CG2 . VAL D 1 118 ? -30.932 1.918   -25.764 1.00 52.54  ? 118 VAL F CG2 1 
ATOM   3917 N  N   . VAL D 1 119 ? -34.264 0.445   -28.737 1.00 50.46  ? 119 VAL F N   1 
ATOM   3918 C  CA  . VAL D 1 119 ? -35.252 0.651   -29.788 1.00 51.15  ? 119 VAL F CA  1 
ATOM   3919 C  C   . VAL D 1 119 ? -35.991 1.979   -29.470 1.00 58.05  ? 119 VAL F C   1 
ATOM   3920 O  O   . VAL D 1 119 ? -36.536 2.144   -28.378 1.00 57.11  ? 119 VAL F O   1 
ATOM   3921 C  CB  . VAL D 1 119 ? -36.171 -0.574  -30.083 1.00 54.78  ? 119 VAL F CB  1 
ATOM   3922 C  CG1 . VAL D 1 119 ? -36.948 -1.030  -28.847 1.00 54.71  ? 119 VAL F CG1 1 
ATOM   3923 C  CG2 . VAL D 1 119 ? -37.115 -0.298  -31.259 1.00 56.40  ? 119 VAL F CG2 1 
ATOM   3924 N  N   . HIS D 1 120 ? -35.934 2.943   -30.409 1.00 58.06  ? 120 HIS F N   1 
ATOM   3925 C  CA  . HIS D 1 120 ? -36.495 4.283   -30.234 1.00 60.07  ? 120 HIS F CA  1 
ATOM   3926 C  C   . HIS D 1 120 ? -37.904 4.434   -30.772 1.00 65.70  ? 120 HIS F C   1 
ATOM   3927 O  O   . HIS D 1 120 ? -38.302 3.698   -31.678 1.00 65.66  ? 120 HIS F O   1 
ATOM   3928 C  CB  . HIS D 1 120 ? -35.554 5.345   -30.831 1.00 61.58  ? 120 HIS F CB  1 
ATOM   3929 C  CG  . HIS D 1 120 ? -34.219 5.416   -30.145 1.00 63.56  ? 120 HIS F CG  1 
ATOM   3930 N  ND1 . HIS D 1 120 ? -33.964 6.349   -29.157 1.00 66.52  ? 120 HIS F ND1 1 
ATOM   3931 C  CD2 . HIS D 1 120 ? -33.104 4.668   -30.338 1.00 63.11  ? 120 HIS F CD2 1 
ATOM   3932 C  CE1 . HIS D 1 120 ? -32.711 6.142   -28.781 1.00 64.21  ? 120 HIS F CE1 1 
ATOM   3933 N  NE2 . HIS D 1 120 ? -32.152 5.143   -29.466 1.00 62.51  ? 120 HIS F NE2 1 
ATOM   3934 N  N   . GLU D 1 121 ? -38.658 5.401   -30.208 1.00 64.18  ? 121 GLU F N   1 
ATOM   3935 C  CA  . GLU D 1 121 ? -40.032 5.723   -30.603 1.00 66.87  ? 121 GLU F CA  1 
ATOM   3936 C  C   . GLU D 1 121 ? -40.107 6.124   -32.084 1.00 73.79  ? 121 GLU F C   1 
ATOM   3937 O  O   . GLU D 1 121 ? -40.892 5.538   -32.828 1.00 74.92  ? 121 GLU F O   1 
ATOM   3938 C  CB  . GLU D 1 121 ? -40.617 6.819   -29.701 1.00 70.54  ? 121 GLU F CB  1 
ATOM   3939 C  CG  . GLU D 1 121 ? -42.109 7.069   -29.902 1.00 85.87  ? 121 GLU F CG  1 
ATOM   3940 C  CD  . GLU D 1 121 ? -42.745 8.123   -29.013 1.00 113.56 ? 121 GLU F CD  1 
ATOM   3941 O  OE1 . GLU D 1 121 ? -43.964 8.013   -28.748 1.00 114.56 ? 121 GLU F OE1 1 
ATOM   3942 O  OE2 . GLU D 1 121 ? -42.034 9.063   -28.587 1.00 107.87 ? 121 GLU F OE2 1 
ATOM   3943 N  N   . LYS D 1 122 ? -39.281 7.095   -32.508 1.00 71.53  ? 122 LYS F N   1 
ATOM   3944 C  CA  . LYS D 1 122 ? -39.285 7.599   -33.881 1.00 73.79  ? 122 LYS F CA  1 
ATOM   3945 C  C   . LYS D 1 122 ? -38.200 6.992   -34.766 1.00 76.60  ? 122 LYS F C   1 
ATOM   3946 O  O   . LYS D 1 122 ? -37.213 6.444   -34.269 1.00 73.50  ? 122 LYS F O   1 
ATOM   3947 C  CB  . LYS D 1 122 ? -39.216 9.136   -33.893 1.00 79.38  ? 122 LYS F CB  1 
ATOM   3948 C  CG  . LYS D 1 122 ? -40.566 9.804   -33.664 1.00 96.39  ? 122 LYS F CG  1 
ATOM   3949 C  CD  . LYS D 1 122 ? -40.480 10.987  -32.704 1.00 109.77 ? 122 LYS F CD  1 
ATOM   3950 C  CE  . LYS D 1 122 ? -40.405 12.319  -33.413 1.00 125.51 ? 122 LYS F CE  1 
ATOM   3951 N  NZ  . LYS D 1 122 ? -40.502 13.453  -32.457 1.00 137.62 ? 122 LYS F NZ  1 
ATOM   3952 N  N   . ALA D 1 123 ? -38.409 7.081   -36.090 1.00 75.55  ? 123 ALA F N   1 
ATOM   3953 C  CA  . ALA D 1 123 ? -37.479 6.600   -37.108 1.00 74.42  ? 123 ALA F CA  1 
ATOM   3954 C  C   . ALA D 1 123 ? -36.212 7.449   -37.096 1.00 78.03  ? 123 ALA F C   1 
ATOM   3955 O  O   . ALA D 1 123 ? -36.280 8.657   -36.849 1.00 80.07  ? 123 ALA F O   1 
ATOM   3956 C  CB  . ALA D 1 123 ? -38.133 6.668   -38.479 1.00 77.90  ? 123 ALA F CB  1 
ATOM   3957 N  N   . ASP D 1 124 ? -35.061 6.810   -37.352 1.00 71.80  ? 124 ASP F N   1 
ATOM   3958 C  CA  . ASP D 1 124 ? -33.749 7.453   -37.414 1.00 100.01 ? 124 ASP F CA  1 
ATOM   3959 C  C   . ASP D 1 124 ? -33.534 8.167   -38.757 1.00 122.43 ? 124 ASP F C   1 
ATOM   3960 O  O   . ASP D 1 124 ? -34.340 8.043   -39.683 1.00 80.91  ? 124 ASP F O   1 
ATOM   3961 C  CB  . ASP D 1 124 ? -32.640 6.416   -37.171 1.00 98.74  ? 124 ASP F CB  1 
ATOM   3962 C  CG  . ASP D 1 124 ? -31.277 7.003   -36.853 1.00 110.47 ? 124 ASP F CG  1 
ATOM   3963 O  OD1 . ASP D 1 124 ? -31.194 7.857   -35.940 1.00 112.17 ? 124 ASP F OD1 1 
ATOM   3964 O  OD2 . ASP D 1 124 ? -30.287 6.587   -37.496 1.00 115.68 ? 124 ASP F OD2 1 
ATOM   3965 N  N   . GLY D 1 141 ? -36.794 9.733   -30.909 1.00 86.23  ? 141 GLY F N   1 
ATOM   3966 C  CA  . GLY D 1 141 ? -37.213 10.465  -29.721 1.00 87.72  ? 141 GLY F CA  1 
ATOM   3967 C  C   . GLY D 1 141 ? -37.068 9.647   -28.453 1.00 87.91  ? 141 GLY F C   1 
ATOM   3968 O  O   . GLY D 1 141 ? -35.946 9.282   -28.071 1.00 85.59  ? 141 GLY F O   1 
ATOM   3969 N  N   . SER D 1 142 ? -38.220 9.348   -27.800 1.00 82.51  ? 142 SER F N   1 
ATOM   3970 C  CA  . SER D 1 142 ? -38.316 8.548   -26.574 1.00 78.82  ? 142 SER F CA  1 
ATOM   3971 C  C   . SER D 1 142 ? -37.716 7.143   -26.754 1.00 76.72  ? 142 SER F C   1 
ATOM   3972 O  O   . SER D 1 142 ? -37.845 6.540   -27.815 1.00 75.33  ? 142 SER F O   1 
ATOM   3973 C  CB  . SER D 1 142 ? -39.772 8.441   -26.134 1.00 82.75  ? 142 SER F CB  1 
ATOM   3974 O  OG  . SER D 1 142 ? -39.930 7.616   -24.993 1.00 87.48  ? 142 SER F OG  1 
ATOM   3975 N  N   . ARG D 1 143 ? -37.057 6.632   -25.713 1.00 69.85  ? 143 ARG F N   1 
ATOM   3976 C  CA  . ARG D 1 143 ? -36.446 5.306   -25.734 1.00 65.05  ? 143 ARG F CA  1 
ATOM   3977 C  C   . ARG D 1 143 ? -37.509 4.304   -25.284 1.00 67.10  ? 143 ARG F C   1 
ATOM   3978 O  O   . ARG D 1 143 ? -37.956 4.357   -24.140 1.00 68.17  ? 143 ARG F O   1 
ATOM   3979 C  CB  . ARG D 1 143 ? -35.191 5.294   -24.850 1.00 62.52  ? 143 ARG F CB  1 
ATOM   3980 C  CG  . ARG D 1 143 ? -34.096 6.197   -25.403 1.00 70.36  ? 143 ARG F CG  1 
ATOM   3981 C  CD  . ARG D 1 143 ? -32.847 6.227   -24.558 1.00 70.19  ? 143 ARG F CD  1 
ATOM   3982 N  NE  . ARG D 1 143 ? -31.948 7.293   -25.003 1.00 69.71  ? 143 ARG F NE  1 
ATOM   3983 C  CZ  . ARG D 1 143 ? -30.719 7.489   -24.538 1.00 74.77  ? 143 ARG F CZ  1 
ATOM   3984 N  NH1 . ARG D 1 143 ? -30.216 6.683   -23.609 1.00 57.32  ? 143 ARG F NH1 1 
ATOM   3985 N  NH2 . ARG D 1 143 ? -29.981 8.491   -24.997 1.00 55.21  ? 143 ARG F NH2 1 
ATOM   3986 N  N   . LEU D 1 144 ? -37.979 3.456   -26.212 1.00 61.53  ? 144 LEU F N   1 
ATOM   3987 C  CA  . LEU D 1 144 ? -39.074 2.510   -25.962 1.00 60.83  ? 144 LEU F CA  1 
ATOM   3988 C  C   . LEU D 1 144 ? -38.706 1.326   -25.099 1.00 60.56  ? 144 LEU F C   1 
ATOM   3989 O  O   . LEU D 1 144 ? -39.440 0.998   -24.185 1.00 59.67  ? 144 LEU F O   1 
ATOM   3990 C  CB  . LEU D 1 144 ? -39.703 2.018   -27.270 1.00 61.51  ? 144 LEU F CB  1 
ATOM   3991 C  CG  . LEU D 1 144 ? -40.475 3.023   -28.103 1.00 68.63  ? 144 LEU F CG  1 
ATOM   3992 C  CD1 . LEU D 1 144 ? -40.889 2.396   -29.409 1.00 69.26  ? 144 LEU F CD1 1 
ATOM   3993 C  CD2 . LEU D 1 144 ? -41.695 3.552   -27.363 1.00 72.32  ? 144 LEU F CD2 1 
ATOM   3994 N  N   . ALA D 1 145 ? -37.631 0.628   -25.447 1.00 54.61  ? 145 ALA F N   1 
ATOM   3995 C  CA  . ALA D 1 145 ? -37.153 -0.521  -24.688 1.00 52.34  ? 145 ALA F CA  1 
ATOM   3996 C  C   . ALA D 1 145 ? -35.656 -0.603  -24.829 1.00 54.43  ? 145 ALA F C   1 
ATOM   3997 O  O   . ALA D 1 145 ? -35.090 -0.032  -25.763 1.00 54.15  ? 145 ALA F O   1 
ATOM   3998 C  CB  . ALA D 1 145 ? -37.806 -1.808  -25.172 1.00 52.82  ? 145 ALA F CB  1 
ATOM   3999 N  N   . CYS D 1 146 ? -35.003 -1.267  -23.878 1.00 50.27  ? 146 CYS F N   1 
ATOM   4000 C  CA  . CYS D 1 146 ? -33.561 -1.424  -23.900 1.00 49.31  ? 146 CYS F CA  1 
ATOM   4001 C  C   . CYS D 1 146 ? -33.118 -2.666  -23.177 1.00 49.70  ? 146 CYS F C   1 
ATOM   4002 O  O   . CYS D 1 146 ? -33.908 -3.314  -22.497 1.00 48.12  ? 146 CYS F O   1 
ATOM   4003 C  CB  . CYS D 1 146 ? -32.850 -0.177  -23.378 1.00 51.40  ? 146 CYS F CB  1 
ATOM   4004 S  SG  . CYS D 1 146 ? -33.353 0.344   -21.717 1.00 57.13  ? 146 CYS F SG  1 
ATOM   4005 N  N   . GLY D 1 147 ? -31.852 -2.993  -23.324 1.00 46.50  ? 147 GLY F N   1 
ATOM   4006 C  CA  . GLY D 1 147 ? -31.264 -4.123  -22.619 1.00 45.35  ? 147 GLY F CA  1 
ATOM   4007 C  C   . GLY D 1 147 ? -29.763 -4.135  -22.724 1.00 45.56  ? 147 GLY F C   1 
ATOM   4008 O  O   . GLY D 1 147 ? -29.201 -3.710  -23.747 1.00 43.95  ? 147 GLY F O   1 
ATOM   4009 N  N   . VAL D 1 148 ? -29.118 -4.700  -21.708 1.00 40.05  ? 148 VAL F N   1 
ATOM   4010 C  CA  . VAL D 1 148 ? -27.664 -4.810  -21.692 1.00 39.71  ? 148 VAL F CA  1 
ATOM   4011 C  C   . VAL D 1 148 ? -27.237 -6.021  -22.541 1.00 43.94  ? 148 VAL F C   1 
ATOM   4012 O  O   . VAL D 1 148 ? -27.745 -7.125  -22.341 1.00 44.75  ? 148 VAL F O   1 
ATOM   4013 C  CB  . VAL D 1 148 ? -27.068 -4.828  -20.261 1.00 44.04  ? 148 VAL F CB  1 
ATOM   4014 C  CG1 . VAL D 1 148 ? -25.543 -4.739  -20.311 1.00 43.47  ? 148 VAL F CG1 1 
ATOM   4015 C  CG2 . VAL D 1 148 ? -27.635 -3.690  -19.414 1.00 45.10  ? 148 VAL F CG2 1 
ATOM   4016 N  N   . ILE D 1 149 ? -26.324 -5.802  -23.501 1.00 40.37  ? 149 ILE F N   1 
ATOM   4017 C  CA  . ILE D 1 149 ? -25.785 -6.847  -24.372 1.00 39.51  ? 149 ILE F CA  1 
ATOM   4018 C  C   . ILE D 1 149 ? -24.843 -7.752  -23.566 1.00 42.80  ? 149 ILE F C   1 
ATOM   4019 O  O   . ILE D 1 149 ? -23.778 -7.325  -23.114 1.00 43.42  ? 149 ILE F O   1 
ATOM   4020 C  CB  . ILE D 1 149 ? -25.128 -6.251  -25.646 1.00 42.68  ? 149 ILE F CB  1 
ATOM   4021 C  CG1 . ILE D 1 149 ? -26.129 -5.332  -26.402 1.00 42.78  ? 149 ILE F CG1 1 
ATOM   4022 C  CG2 . ILE D 1 149 ? -24.580 -7.361  -26.566 1.00 42.56  ? 149 ILE F CG2 1 
ATOM   4023 C  CD1 . ILE D 1 149 ? -25.476 -4.313  -27.384 1.00 45.41  ? 149 ILE F CD1 1 
ATOM   4024 N  N   . GLY D 1 150 ? -25.262 -8.992  -23.388 1.00 38.65  ? 150 GLY F N   1 
ATOM   4025 C  CA  . GLY D 1 150 ? -24.505 -9.969  -22.631 1.00 39.42  ? 150 GLY F CA  1 
ATOM   4026 C  C   . GLY D 1 150 ? -23.971 -11.106 -23.463 1.00 46.31  ? 150 GLY F C   1 
ATOM   4027 O  O   . GLY D 1 150 ? -24.453 -11.346 -24.569 1.00 46.82  ? 150 GLY F O   1 
ATOM   4028 N  N   . ILE D 1 151 ? -22.964 -11.803 -22.918 1.00 44.20  ? 151 ILE F N   1 
ATOM   4029 C  CA  . ILE D 1 151 ? -22.285 -12.959 -23.513 1.00 46.47  ? 151 ILE F CA  1 
ATOM   4030 C  C   . ILE D 1 151 ? -23.250 -14.154 -23.545 1.00 51.93  ? 151 ILE F C   1 
ATOM   4031 O  O   . ILE D 1 151 ? -23.923 -14.426 -22.552 1.00 50.65  ? 151 ILE F O   1 
ATOM   4032 C  CB  . ILE D 1 151 ? -20.972 -13.252 -22.715 1.00 50.50  ? 151 ILE F CB  1 
ATOM   4033 C  CG1 . ILE D 1 151 ? -19.905 -12.169 -23.015 1.00 50.45  ? 151 ILE F CG1 1 
ATOM   4034 C  CG2 . ILE D 1 151 ? -20.420 -14.666 -22.990 1.00 53.77  ? 151 ILE F CG2 1 
ATOM   4035 C  CD1 . ILE D 1 151 ? -18.802 -11.960 -21.881 1.00 59.05  ? 151 ILE F CD1 1 
ATOM   4036 N  N   . ALA D 1 152 ? -23.326 -14.852 -24.694 1.00 50.25  ? 152 ALA F N   1 
ATOM   4037 C  CA  . ALA D 1 152 ? -24.221 -15.999 -24.834 1.00 51.34  ? 152 ALA F CA  1 
ATOM   4038 C  C   . ALA D 1 152 ? -23.439 -17.282 -25.110 1.00 57.87  ? 152 ALA F C   1 
ATOM   4039 O  O   . ALA D 1 152 ? -22.304 -17.216 -25.584 1.00 57.39  ? 152 ALA F O   1 
ATOM   4040 C  CB  . ALA D 1 152 ? -25.234 -15.739 -25.940 1.00 51.45  ? 152 ALA F CB  1 
ATOM   4041 N  N   . GLN D 1 153 ? -24.048 -18.446 -24.798 1.00 57.16  ? 153 GLN F N   1 
ATOM   4042 C  CA  . GLN D 1 153 ? -23.469 -19.776 -25.014 1.00 62.89  ? 153 GLN F CA  1 
ATOM   4043 C  C   . GLN D 1 153 ? -23.303 -20.084 -26.511 1.00 80.15  ? 153 GLN F C   1 
ATOM   4044 O  O   . GLN D 1 153 ? -24.249 -19.830 -27.291 1.00 83.25  ? 153 GLN F O   1 
ATOM   4045 C  CB  . GLN D 1 153 ? -24.326 -20.849 -24.321 1.00 66.30  ? 153 GLN F CB  1 
ATOM   4046 C  CG  . GLN D 1 153 ? -23.641 -22.208 -24.189 1.00 83.22  ? 153 GLN F CG  1 
ATOM   4047 C  CD  . GLN D 1 153 ? -24.256 -23.059 -23.106 1.00 105.99 ? 153 GLN F CD  1 
ATOM   4048 O  OE1 . GLN D 1 153 ? -25.473 -23.274 -23.052 1.00 102.44 ? 153 GLN F OE1 1 
ATOM   4049 N  NE2 . GLN D 1 153 ? -23.419 -23.582 -22.225 1.00 101.66 ? 153 GLN F NE2 1 
ATOM   4050 O  OXT . GLN D 1 153 ? -22.220 -20.576 -26.895 1.00 101.17 ? 153 GLN F OXT 1 
HETATM 4051 C  C3  . D7Z E 2 .   ? -3.537  -11.978 -26.352 0.40 68.92  ? 201 D7Z A C3  1 
HETATM 4052 C  C6  . D7Z E 2 .   ? -0.709  -11.185 -26.928 0.40 68.63  ? 201 D7Z A C6  1 
HETATM 4053 N  N1  . D7Z E 2 .   ? -0.278  -13.547 -27.609 0.40 68.28  ? 201 D7Z A N1  1 
HETATM 4054 C  C1  . D7Z E 2 .   ? -1.306  -12.502 -27.437 0.40 68.65  ? 201 D7Z A C1  1 
HETATM 4055 C  C2  . D7Z E 2 .   ? -2.408  -13.006 -26.497 0.40 69.00  ? 201 D7Z A C2  1 
HETATM 4056 C  C4  . D7Z E 2 .   ? -2.995  -10.616 -25.889 0.40 68.93  ? 201 D7Z A C4  1 
HETATM 4057 C  C5  . D7Z E 2 .   ? -1.794  -10.118 -26.714 0.40 68.88  ? 201 D7Z A C5  1 
HETATM 4058 N  N2  . D7Z E 2 .   ? -2.895  -14.323 -26.955 0.40 69.23  ? 201 D7Z A N2  1 
HETATM 4059 PT PT8 . D7Z E 2 .   ? -1.282  -15.312 -27.709 0.40 69.14  ? 201 D7Z A PT8 1 
HETATM 4060 CL CL1 . D7Z E 2 .   ? -2.555  -17.369 -27.851 0.40 70.41  ? 201 D7Z A CL1 1 
HETATM 4061 C  C3  . D7Z F 2 .   ? -5.281  -17.234 -31.048 0.30 104.06 ? 201 D7Z B C3  1 
HETATM 4062 C  C6  . D7Z F 2 .   ? -2.746  -18.222 -32.290 0.30 104.01 ? 201 D7Z B C6  1 
HETATM 4063 N  N1  . D7Z F 2 .   ? -1.873  -15.888 -32.141 0.30 104.21 ? 201 D7Z B N1  1 
HETATM 4064 C  C1  . D7Z F 2 .   ? -2.827  -16.865 -31.581 0.30 104.12 ? 201 D7Z B C1  1 
HETATM 4065 C  C2  . D7Z F 2 .   ? -4.242  -16.280 -31.649 0.30 104.11 ? 201 D7Z B C2  1 
HETATM 4066 C  C4  . D7Z F 2 .   ? -5.215  -18.625 -31.700 0.30 104.01 ? 201 D7Z B C4  1 
HETATM 4067 C  C5  . D7Z F 2 .   ? -3.793  -19.210 -31.752 0.30 104.00 ? 201 D7Z B C5  1 
HETATM 4068 N  N2  . D7Z F 2 .   ? -4.257  -14.950 -31.008 0.30 104.17 ? 201 D7Z B N2  1 
HETATM 4069 PT PT8 . D7Z F 2 .   ? -2.499  -14.057 -31.513 0.30 104.29 ? 201 D7Z B PT8 1 
HETATM 4070 CL CL1 . D7Z F 2 .   ? -3.270  -11.899 -30.719 0.30 104.18 ? 201 D7Z B CL1 1 
HETATM 4071 C  C3  . D7Z G 2 .   ? -12.331 -10.663 -23.104 0.30 66.24  ? 201 D7Z D C3  1 
HETATM 4072 C  C6  . D7Z G 2 .   ? -15.028 -11.652 -22.255 0.30 65.76  ? 201 D7Z D C6  1 
HETATM 4073 N  N1  . D7Z G 2 .   ? -15.353 -9.477  -21.086 0.30 65.17  ? 201 D7Z D N1  1 
HETATM 4074 C  C1  . D7Z G 2 .   ? -14.644 -10.170 -22.176 0.30 65.55  ? 201 D7Z D C1  1 
HETATM 4075 C  C2  . D7Z G 2 .   ? -13.133 -9.987  -21.986 0.30 65.82  ? 201 D7Z D C2  1 
HETATM 4076 C  C4  . D7Z G 2 .   ? -12.716 -12.144 -23.263 0.30 66.42  ? 201 D7Z D C4  1 
HETATM 4077 C  C5  . D7Z G 2 .   ? -14.234 -12.383 -23.349 0.30 66.21  ? 201 D7Z D C5  1 
HETATM 4078 N  N2  . D7Z G 2 .   ? -12.816 -8.550  -21.844 0.30 65.57  ? 201 D7Z D N2  1 
HETATM 4079 PT PT8 . D7Z G 2 .   ? -14.366 -7.717  -20.819 0.30 65.44  ? 201 D7Z D PT8 1 
HETATM 4080 CL CL1 . D7Z G 2 .   ? -13.217 -5.595  -20.609 0.30 63.69  ? 201 D7Z D CL1 1 
HETATM 4081 C  C3  . D7Z H 2 .   ? -12.342 -3.997  -24.212 0.20 70.83  ? 201 D7Z F C3  1 
HETATM 4082 C  C6  . D7Z H 2 .   ? -14.933 -2.670  -23.522 0.20 70.67  ? 201 D7Z F C6  1 
HETATM 4083 N  N1  . D7Z H 2 .   ? -16.079 -4.790  -24.154 0.20 71.04  ? 201 D7Z F N1  1 
HETATM 4084 C  C1  . D7Z H 2 .   ? -14.812 -4.188  -23.700 0.20 70.76  ? 201 D7Z F C1  1 
HETATM 4085 C  C2  . D7Z H 2 .   ? -13.693 -4.543  -24.686 0.20 70.73  ? 201 D7Z F C2  1 
HETATM 4086 C  C4  . D7Z H 2 .   ? -12.403 -2.479  -23.969 0.20 70.83  ? 201 D7Z F C4  1 
HETATM 4087 C  C5  . D7Z H 2 .   ? -13.596 -2.037  -23.101 0.20 70.76  ? 201 D7Z F C5  1 
HETATM 4088 N  N2  . D7Z H 2 .   ? -13.672 -6.002  -24.915 0.20 70.85  ? 201 D7Z F N2  1 
HETATM 4089 PT PT8 . D7Z H 2 .   ? -15.619 -6.588  -24.998 0.20 71.33  ? 201 D7Z F PT8 1 
HETATM 4090 CL CL1 . D7Z H 2 .   ? -15.034 -8.742  -25.945 0.20 70.65  ? 201 D7Z F CL1 1 
# 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ALA 1   1   1   ALA ALA A . n 
A 1 2   THR 2   2   2   THR THR A . n 
A 1 3   LYS 3   3   3   LYS LYS A . n 
A 1 4   ALA 4   4   4   ALA ALA A . n 
A 1 5   VAL 5   5   5   VAL VAL A . n 
A 1 6   CYS 6   6   6   CYS CYS A . n 
A 1 7   VAL 7   7   7   VAL VAL A . n 
A 1 8   LEU 8   8   8   LEU LEU A . n 
A 1 9   LYS 9   9   9   LYS LYS A . n 
A 1 10  GLY 10  10  10  GLY GLY A . n 
A 1 11  ASP 11  11  11  ASP ASP A . n 
A 1 12  GLY 12  12  12  GLY GLY A . n 
A 1 13  PRO 13  13  13  PRO PRO A . n 
A 1 14  VAL 14  14  14  VAL VAL A . n 
A 1 15  GLN 15  15  15  GLN GLN A . n 
A 1 16  GLY 16  16  16  GLY GLY A . n 
A 1 17  ILE 17  17  17  ILE ILE A . n 
A 1 18  ILE 18  18  18  ILE ILE A . n 
A 1 19  ASN 19  19  19  ASN ASN A . n 
A 1 20  PHE 20  20  20  PHE PHE A . n 
A 1 21  GLU 21  21  21  GLU GLU A . n 
A 1 22  GLN 22  22  22  GLN GLN A . n 
A 1 23  LYS 23  23  23  LYS LYS A . n 
A 1 24  GLU 24  24  24  GLU GLU A . n 
A 1 25  SER 25  25  25  SER SER A . n 
A 1 26  ASN 26  26  26  ASN ASN A . n 
A 1 27  GLY 27  27  27  GLY GLY A . n 
A 1 28  PRO 28  28  28  PRO PRO A . n 
A 1 29  VAL 29  29  29  VAL VAL A . n 
A 1 30  LYS 30  30  30  LYS LYS A . n 
A 1 31  VAL 31  31  31  VAL VAL A . n 
A 1 32  TRP 32  32  32  TRP TRP A . n 
A 1 33  GLY 33  33  33  GLY GLY A . n 
A 1 34  SER 34  34  34  SER SER A . n 
A 1 35  ILE 35  35  35  ILE ILE A . n 
A 1 36  LYS 36  36  36  LYS LYS A . n 
A 1 37  GLY 37  37  37  GLY GLY A . n 
A 1 38  LEU 38  38  38  LEU LEU A . n 
A 1 39  THR 39  39  39  THR THR A . n 
A 1 40  GLU 40  40  40  GLU GLU A . n 
A 1 41  GLY 41  41  41  GLY GLY A . n 
A 1 42  LEU 42  42  42  LEU LEU A . n 
A 1 43  HIS 43  43  43  HIS HIS A . n 
A 1 44  GLY 44  44  44  GLY GLY A . n 
A 1 45  PHE 45  45  45  PHE PHE A . n 
A 1 46  HIS 46  46  46  HIS HIS A . n 
A 1 47  VAL 47  47  47  VAL VAL A . n 
A 1 48  HIS 48  48  48  HIS HIS A . n 
A 1 49  GLU 49  49  49  GLU GLU A . n 
A 1 50  PHE 50  50  50  PHE PHE A . n 
A 1 51  GLY 51  51  51  GLY GLY A . n 
A 1 52  ASP 52  52  52  ASP ASP A . n 
A 1 53  ASN 53  53  53  ASN ASN A . n 
A 1 54  THR 54  54  54  THR THR A . n 
A 1 55  ALA 55  55  55  ALA ALA A . n 
A 1 56  GLY 56  56  56  GLY GLY A . n 
A 1 57  CYS 57  57  57  CYS CYS A . n 
A 1 58  THR 58  58  58  THR THR A . n 
A 1 59  SER 59  59  59  SER SER A . n 
A 1 60  ALA 60  60  60  ALA ALA A . n 
A 1 61  GLY 61  61  61  GLY GLY A . n 
A 1 62  PRO 62  62  62  PRO PRO A . n 
A 1 63  HIS 63  63  63  HIS HIS A . n 
A 1 64  PHE 64  64  64  PHE PHE A . n 
A 1 65  ASN 65  65  65  ASN ASN A . n 
A 1 66  PRO 66  66  66  PRO PRO A . n 
A 1 67  LEU 67  67  67  LEU LEU A . n 
A 1 68  SER 68  68  68  SER SER A . n 
A 1 69  ARG 69  69  69  ARG ARG A . n 
A 1 70  LYS 70  70  70  LYS LYS A . n 
A 1 71  HIS 71  71  71  HIS HIS A . n 
A 1 72  GLY 72  72  72  GLY GLY A . n 
A 1 73  GLY 73  73  73  GLY GLY A . n 
A 1 74  PRO 74  74  74  PRO PRO A . n 
A 1 75  LYS 75  75  75  LYS LYS A . n 
A 1 76  ASP 76  76  76  ASP ASP A . n 
A 1 77  GLU 77  77  77  GLU GLU A . n 
A 1 78  GLU 78  78  78  GLU GLU A . n 
A 1 79  ARG 79  79  79  ARG ARG A . n 
A 1 80  HIS 80  80  80  HIS HIS A . n 
A 1 81  VAL 81  81  81  VAL VAL A . n 
A 1 82  GLY 82  82  82  GLY GLY A . n 
A 1 83  ASP 83  83  83  ASP ASP A . n 
A 1 84  LEU 84  84  84  LEU LEU A . n 
A 1 85  GLY 85  85  85  GLY GLY A . n 
A 1 86  ASN 86  86  86  ASN ASN A . n 
A 1 87  VAL 87  87  87  VAL VAL A . n 
A 1 88  THR 88  88  88  THR THR A . n 
A 1 89  ALA 89  89  89  ALA ALA A . n 
A 1 90  ASP 90  90  90  ASP ASP A . n 
A 1 91  LYS 91  91  91  LYS LYS A . n 
A 1 92  ASP 92  92  92  ASP ASP A . n 
A 1 93  GLY 93  93  93  GLY GLY A . n 
A 1 94  VAL 94  94  94  VAL VAL A . n 
A 1 95  ALA 95  95  95  ALA ALA A . n 
A 1 96  ASP 96  96  96  ASP ASP A . n 
A 1 97  VAL 97  97  97  VAL VAL A . n 
A 1 98  SER 98  98  98  SER SER A . n 
A 1 99  ILE 99  99  99  ILE ILE A . n 
A 1 100 GLU 100 100 100 GLU GLU A . n 
A 1 101 ASP 101 101 101 ASP ASP A . n 
A 1 102 SER 102 102 102 SER SER A . n 
A 1 103 VAL 103 103 103 VAL VAL A . n 
A 1 104 ILE 104 104 104 ILE ILE A . n 
A 1 105 SER 105 105 105 SER SER A . n 
A 1 106 LEU 106 106 106 LEU LEU A . n 
A 1 107 SER 107 107 107 SER SER A . n 
A 1 108 GLY 108 108 108 GLY GLY A . n 
A 1 109 ASP 109 109 109 ASP ASP A . n 
A 1 110 HIS 110 110 110 HIS HIS A . n 
A 1 111 CYS 111 111 111 CYS CYS A . n 
A 1 112 ILE 112 112 112 ILE ILE A . n 
A 1 113 ILE 113 113 113 ILE ILE A . n 
A 1 114 GLY 114 114 114 GLY GLY A . n 
A 1 115 ARG 115 115 115 ARG ARG A . n 
A 1 116 THR 116 116 116 THR THR A . n 
A 1 117 LEU 117 117 117 LEU LEU A . n 
A 1 118 VAL 118 118 118 VAL VAL A . n 
A 1 119 VAL 119 119 119 VAL VAL A . n 
A 1 120 HIS 120 120 120 HIS HIS A . n 
A 1 121 GLU 121 121 121 GLU GLU A . n 
A 1 122 LYS 122 122 122 LYS LYS A . n 
A 1 123 ALA 123 123 123 ALA ALA A . n 
A 1 124 ASP 124 124 124 ASP ASP A . n 
A 1 125 ASP 125 125 125 ASP ASP A . n 
A 1 126 LEU 126 126 126 LEU LEU A . n 
A 1 127 GLY 127 127 127 GLY GLY A . n 
A 1 128 LYS 128 128 128 LYS LYS A . n 
A 1 129 GLY 129 129 129 GLY GLY A . n 
A 1 130 GLY 130 130 130 GLY GLY A . n 
A 1 131 ASN 131 131 131 ASN ASN A . n 
A 1 132 GLU 132 132 132 GLU GLU A . n 
A 1 133 GLU 133 133 133 GLU GLU A . n 
A 1 134 SER 134 134 134 SER SER A . n 
A 1 135 THR 135 135 135 THR THR A . n 
A 1 136 LYS 136 136 136 LYS LYS A . n 
A 1 137 THR 137 137 137 THR THR A . n 
A 1 138 GLY 138 138 138 GLY GLY A . n 
A 1 139 ASN 139 139 139 ASN ASN A . n 
A 1 140 ALA 140 140 140 ALA ALA A . n 
A 1 141 GLY 141 141 141 GLY GLY A . n 
A 1 142 SER 142 142 142 SER SER A . n 
A 1 143 ARG 143 143 143 ARG ARG A . n 
A 1 144 LEU 144 144 144 LEU LEU A . n 
A 1 145 ALA 145 145 145 ALA ALA A . n 
A 1 146 CYS 146 146 146 CYS CYS A . n 
A 1 147 GLY 147 147 147 GLY GLY A . n 
A 1 148 VAL 148 148 148 VAL VAL A . n 
A 1 149 ILE 149 149 149 ILE ILE A . n 
A 1 150 GLY 150 150 150 GLY GLY A . n 
A 1 151 ILE 151 151 151 ILE ILE A . n 
A 1 152 ALA 152 152 152 ALA ALA A . n 
A 1 153 GLN 153 153 153 GLN GLN A . n 
B 1 1   ALA 1   1   1   ALA ALA B . n 
B 1 2   THR 2   2   2   THR THR B . n 
B 1 3   LYS 3   3   3   LYS LYS B . n 
B 1 4   ALA 4   4   4   ALA ALA B . n 
B 1 5   VAL 5   5   5   VAL VAL B . n 
B 1 6   CYS 6   6   6   CYS CYS B . n 
B 1 7   VAL 7   7   7   VAL VAL B . n 
B 1 8   LEU 8   8   8   LEU LEU B . n 
B 1 9   LYS 9   9   9   LYS LYS B . n 
B 1 10  GLY 10  10  10  GLY GLY B . n 
B 1 11  ASP 11  11  11  ASP ASP B . n 
B 1 12  GLY 12  12  12  GLY GLY B . n 
B 1 13  PRO 13  13  13  PRO PRO B . n 
B 1 14  VAL 14  14  14  VAL VAL B . n 
B 1 15  GLN 15  15  15  GLN GLN B . n 
B 1 16  GLY 16  16  16  GLY GLY B . n 
B 1 17  ILE 17  17  17  ILE ILE B . n 
B 1 18  ILE 18  18  18  ILE ILE B . n 
B 1 19  ASN 19  19  19  ASN ASN B . n 
B 1 20  PHE 20  20  20  PHE PHE B . n 
B 1 21  GLU 21  21  21  GLU GLU B . n 
B 1 22  GLN 22  22  22  GLN GLN B . n 
B 1 23  LYS 23  23  23  LYS LYS B . n 
B 1 24  GLU 24  24  24  GLU GLU B . n 
B 1 25  SER 25  25  25  SER SER B . n 
B 1 26  ASN 26  26  26  ASN ASN B . n 
B 1 27  GLY 27  27  27  GLY GLY B . n 
B 1 28  PRO 28  28  28  PRO PRO B . n 
B 1 29  VAL 29  29  29  VAL VAL B . n 
B 1 30  LYS 30  30  30  LYS LYS B . n 
B 1 31  VAL 31  31  31  VAL VAL B . n 
B 1 32  TRP 32  32  32  TRP TRP B . n 
B 1 33  GLY 33  33  33  GLY GLY B . n 
B 1 34  SER 34  34  34  SER SER B . n 
B 1 35  ILE 35  35  35  ILE ILE B . n 
B 1 36  LYS 36  36  36  LYS LYS B . n 
B 1 37  GLY 37  37  37  GLY GLY B . n 
B 1 38  LEU 38  38  38  LEU LEU B . n 
B 1 39  THR 39  39  39  THR THR B . n 
B 1 40  GLU 40  40  40  GLU GLU B . n 
B 1 41  GLY 41  41  41  GLY GLY B . n 
B 1 42  LEU 42  42  42  LEU LEU B . n 
B 1 43  HIS 43  43  43  HIS HIS B . n 
B 1 44  GLY 44  44  44  GLY GLY B . n 
B 1 45  PHE 45  45  45  PHE PHE B . n 
B 1 46  HIS 46  46  46  HIS HIS B . n 
B 1 47  VAL 47  47  47  VAL VAL B . n 
B 1 48  HIS 48  48  48  HIS HIS B . n 
B 1 49  GLU 49  49  49  GLU GLU B . n 
B 1 50  PHE 50  50  50  PHE PHE B . n 
B 1 51  GLY 51  51  51  GLY GLY B . n 
B 1 52  ASP 52  52  52  ASP ASP B . n 
B 1 53  ASN 53  53  53  ASN ASN B . n 
B 1 54  THR 54  54  54  THR THR B . n 
B 1 55  ALA 55  55  55  ALA ALA B . n 
B 1 56  GLY 56  56  56  GLY GLY B . n 
B 1 57  CYS 57  57  57  CYS CYS B . n 
B 1 58  THR 58  58  58  THR THR B . n 
B 1 59  SER 59  59  59  SER SER B . n 
B 1 60  ALA 60  60  60  ALA ALA B . n 
B 1 61  GLY 61  61  61  GLY GLY B . n 
B 1 62  PRO 62  62  62  PRO PRO B . n 
B 1 63  HIS 63  63  63  HIS HIS B . n 
B 1 64  PHE 64  64  64  PHE PHE B . n 
B 1 65  ASN 65  65  65  ASN ASN B . n 
B 1 66  PRO 66  66  66  PRO PRO B . n 
B 1 67  LEU 67  67  67  LEU LEU B . n 
B 1 68  SER 68  68  68  SER SER B . n 
B 1 69  ARG 69  69  69  ARG ARG B . n 
B 1 70  LYS 70  70  70  LYS LYS B . n 
B 1 71  HIS 71  71  71  HIS HIS B . n 
B 1 72  GLY 72  72  72  GLY GLY B . n 
B 1 73  GLY 73  73  73  GLY GLY B . n 
B 1 74  PRO 74  74  74  PRO PRO B . n 
B 1 75  LYS 75  75  75  LYS LYS B . n 
B 1 76  ASP 76  76  76  ASP ASP B . n 
B 1 77  GLU 77  77  77  GLU GLU B . n 
B 1 78  GLU 78  78  78  GLU GLU B . n 
B 1 79  ARG 79  79  79  ARG ARG B . n 
B 1 80  HIS 80  80  80  HIS HIS B . n 
B 1 81  VAL 81  81  81  VAL VAL B . n 
B 1 82  GLY 82  82  82  GLY GLY B . n 
B 1 83  ASP 83  83  83  ASP ASP B . n 
B 1 84  LEU 84  84  84  LEU LEU B . n 
B 1 85  GLY 85  85  85  GLY GLY B . n 
B 1 86  ASN 86  86  86  ASN ASN B . n 
B 1 87  VAL 87  87  87  VAL VAL B . n 
B 1 88  THR 88  88  88  THR THR B . n 
B 1 89  ALA 89  89  89  ALA ALA B . n 
B 1 90  ASP 90  90  90  ASP ASP B . n 
B 1 91  LYS 91  91  91  LYS LYS B . n 
B 1 92  ASP 92  92  92  ASP ASP B . n 
B 1 93  GLY 93  93  93  GLY GLY B . n 
B 1 94  VAL 94  94  94  VAL VAL B . n 
B 1 95  ALA 95  95  95  ALA ALA B . n 
B 1 96  ASP 96  96  96  ASP ASP B . n 
B 1 97  VAL 97  97  97  VAL VAL B . n 
B 1 98  SER 98  98  98  SER SER B . n 
B 1 99  ILE 99  99  99  ILE ILE B . n 
B 1 100 GLU 100 100 100 GLU GLU B . n 
B 1 101 ASP 101 101 101 ASP ASP B . n 
B 1 102 SER 102 102 102 SER SER B . n 
B 1 103 VAL 103 103 103 VAL VAL B . n 
B 1 104 ILE 104 104 104 ILE ILE B . n 
B 1 105 SER 105 105 105 SER SER B . n 
B 1 106 LEU 106 106 106 LEU LEU B . n 
B 1 107 SER 107 107 107 SER SER B . n 
B 1 108 GLY 108 108 108 GLY GLY B . n 
B 1 109 ASP 109 109 109 ASP ASP B . n 
B 1 110 HIS 110 110 110 HIS HIS B . n 
B 1 111 CYS 111 111 111 CYS CYS B . n 
B 1 112 ILE 112 112 112 ILE ILE B . n 
B 1 113 ILE 113 113 113 ILE ILE B . n 
B 1 114 GLY 114 114 114 GLY GLY B . n 
B 1 115 ARG 115 115 115 ARG ARG B . n 
B 1 116 THR 116 116 116 THR THR B . n 
B 1 117 LEU 117 117 117 LEU LEU B . n 
B 1 118 VAL 118 118 118 VAL VAL B . n 
B 1 119 VAL 119 119 119 VAL VAL B . n 
B 1 120 HIS 120 120 120 HIS HIS B . n 
B 1 121 GLU 121 121 121 GLU GLU B . n 
B 1 122 LYS 122 122 122 LYS LYS B . n 
B 1 123 ALA 123 123 123 ALA ALA B . n 
B 1 124 ASP 124 124 124 ASP ASP B . n 
B 1 125 ASP 125 125 125 ASP ASP B . n 
B 1 126 LEU 126 126 126 LEU LEU B . n 
B 1 127 GLY 127 127 127 GLY GLY B . n 
B 1 128 LYS 128 128 128 LYS LYS B . n 
B 1 129 GLY 129 129 129 GLY GLY B . n 
B 1 130 GLY 130 130 130 GLY GLY B . n 
B 1 131 ASN 131 131 131 ASN ASN B . n 
B 1 132 GLU 132 132 132 GLU GLU B . n 
B 1 133 GLU 133 133 133 GLU GLU B . n 
B 1 134 SER 134 134 134 SER SER B . n 
B 1 135 THR 135 135 135 THR THR B . n 
B 1 136 LYS 136 136 136 LYS LYS B . n 
B 1 137 THR 137 137 137 THR THR B . n 
B 1 138 GLY 138 138 138 GLY GLY B . n 
B 1 139 ASN 139 139 139 ASN ASN B . n 
B 1 140 ALA 140 140 140 ALA ALA B . n 
B 1 141 GLY 141 141 141 GLY GLY B . n 
B 1 142 SER 142 142 142 SER SER B . n 
B 1 143 ARG 143 143 143 ARG ARG B . n 
B 1 144 LEU 144 144 144 LEU LEU B . n 
B 1 145 ALA 145 145 145 ALA ALA B . n 
B 1 146 CYS 146 146 146 CYS CYS B . n 
B 1 147 GLY 147 147 147 GLY GLY B . n 
B 1 148 VAL 148 148 148 VAL VAL B . n 
B 1 149 ILE 149 149 149 ILE ILE B . n 
B 1 150 GLY 150 150 150 GLY GLY B . n 
B 1 151 ILE 151 151 151 ILE ILE B . n 
B 1 152 ALA 152 152 152 ALA ALA B . n 
B 1 153 GLN 153 153 153 GLN GLN B . n 
C 1 1   ALA 1   1   1   ALA ALA D . n 
C 1 2   THR 2   2   2   THR THR D . n 
C 1 3   LYS 3   3   3   LYS LYS D . n 
C 1 4   ALA 4   4   4   ALA ALA D . n 
C 1 5   VAL 5   5   5   VAL VAL D . n 
C 1 6   CYS 6   6   6   CYS CYS D . n 
C 1 7   VAL 7   7   7   VAL VAL D . n 
C 1 8   LEU 8   8   8   LEU LEU D . n 
C 1 9   LYS 9   9   9   LYS LYS D . n 
C 1 10  GLY 10  10  10  GLY GLY D . n 
C 1 11  ASP 11  11  11  ASP ASP D . n 
C 1 12  GLY 12  12  12  GLY GLY D . n 
C 1 13  PRO 13  13  13  PRO PRO D . n 
C 1 14  VAL 14  14  14  VAL VAL D . n 
C 1 15  GLN 15  15  15  GLN GLN D . n 
C 1 16  GLY 16  16  16  GLY GLY D . n 
C 1 17  ILE 17  17  17  ILE ILE D . n 
C 1 18  ILE 18  18  18  ILE ILE D . n 
C 1 19  ASN 19  19  19  ASN ASN D . n 
C 1 20  PHE 20  20  20  PHE PHE D . n 
C 1 21  GLU 21  21  21  GLU GLU D . n 
C 1 22  GLN 22  22  22  GLN GLN D . n 
C 1 23  LYS 23  23  23  LYS LYS D . n 
C 1 24  GLU 24  24  24  GLU GLU D . n 
C 1 25  SER 25  25  25  SER SER D . n 
C 1 26  ASN 26  26  26  ASN ASN D . n 
C 1 27  GLY 27  27  27  GLY GLY D . n 
C 1 28  PRO 28  28  28  PRO PRO D . n 
C 1 29  VAL 29  29  29  VAL VAL D . n 
C 1 30  LYS 30  30  30  LYS LYS D . n 
C 1 31  VAL 31  31  31  VAL VAL D . n 
C 1 32  TRP 32  32  32  TRP TRP D . n 
C 1 33  GLY 33  33  33  GLY GLY D . n 
C 1 34  SER 34  34  34  SER SER D . n 
C 1 35  ILE 35  35  35  ILE ILE D . n 
C 1 36  LYS 36  36  36  LYS LYS D . n 
C 1 37  GLY 37  37  37  GLY GLY D . n 
C 1 38  LEU 38  38  38  LEU LEU D . n 
C 1 39  THR 39  39  39  THR THR D . n 
C 1 40  GLU 40  40  40  GLU GLU D . n 
C 1 41  GLY 41  41  41  GLY GLY D . n 
C 1 42  LEU 42  42  42  LEU LEU D . n 
C 1 43  HIS 43  43  43  HIS HIS D . n 
C 1 44  GLY 44  44  44  GLY GLY D . n 
C 1 45  PHE 45  45  45  PHE PHE D . n 
C 1 46  HIS 46  46  46  HIS HIS D . n 
C 1 47  VAL 47  47  47  VAL VAL D . n 
C 1 48  HIS 48  48  48  HIS HIS D . n 
C 1 49  GLU 49  49  49  GLU GLU D . n 
C 1 50  PHE 50  50  50  PHE PHE D . n 
C 1 51  GLY 51  51  51  GLY GLY D . n 
C 1 52  ASP 52  52  52  ASP ASP D . n 
C 1 53  ASN 53  53  53  ASN ASN D . n 
C 1 54  THR 54  54  54  THR THR D . n 
C 1 55  ALA 55  55  55  ALA ALA D . n 
C 1 56  GLY 56  56  56  GLY GLY D . n 
C 1 57  CYS 57  57  57  CYS CYS D . n 
C 1 58  THR 58  58  58  THR THR D . n 
C 1 59  SER 59  59  59  SER SER D . n 
C 1 60  ALA 60  60  60  ALA ALA D . n 
C 1 61  GLY 61  61  61  GLY GLY D . n 
C 1 62  PRO 62  62  62  PRO PRO D . n 
C 1 63  HIS 63  63  63  HIS HIS D . n 
C 1 64  PHE 64  64  64  PHE PHE D . n 
C 1 65  ASN 65  65  65  ASN ASN D . n 
C 1 66  PRO 66  66  66  PRO PRO D . n 
C 1 67  LEU 67  67  67  LEU LEU D . n 
C 1 68  SER 68  68  ?   ?   ?   D . n 
C 1 69  ARG 69  69  ?   ?   ?   D . n 
C 1 70  LYS 70  70  ?   ?   ?   D . n 
C 1 71  HIS 71  71  ?   ?   ?   D . n 
C 1 72  GLY 72  72  ?   ?   ?   D . n 
C 1 73  GLY 73  73  ?   ?   ?   D . n 
C 1 74  PRO 74  74  ?   ?   ?   D . n 
C 1 75  LYS 75  75  ?   ?   ?   D . n 
C 1 76  ASP 76  76  ?   ?   ?   D . n 
C 1 77  GLU 77  77  ?   ?   ?   D . n 
C 1 78  GLU 78  78  ?   ?   ?   D . n 
C 1 79  ARG 79  79  79  ARG ARG D . n 
C 1 80  HIS 80  80  80  HIS HIS D . n 
C 1 81  VAL 81  81  81  VAL VAL D . n 
C 1 82  GLY 82  82  82  GLY GLY D . n 
C 1 83  ASP 83  83  83  ASP ASP D . n 
C 1 84  LEU 84  84  84  LEU LEU D . n 
C 1 85  GLY 85  85  85  GLY GLY D . n 
C 1 86  ASN 86  86  86  ASN ASN D . n 
C 1 87  VAL 87  87  87  VAL VAL D . n 
C 1 88  THR 88  88  88  THR THR D . n 
C 1 89  ALA 89  89  89  ALA ALA D . n 
C 1 90  ASP 90  90  90  ASP ASP D . n 
C 1 91  LYS 91  91  91  LYS LYS D . n 
C 1 92  ASP 92  92  92  ASP ASP D . n 
C 1 93  GLY 93  93  93  GLY GLY D . n 
C 1 94  VAL 94  94  94  VAL VAL D . n 
C 1 95  ALA 95  95  95  ALA ALA D . n 
C 1 96  ASP 96  96  96  ASP ASP D . n 
C 1 97  VAL 97  97  97  VAL VAL D . n 
C 1 98  SER 98  98  98  SER SER D . n 
C 1 99  ILE 99  99  99  ILE ILE D . n 
C 1 100 GLU 100 100 100 GLU GLU D . n 
C 1 101 ASP 101 101 101 ASP ASP D . n 
C 1 102 SER 102 102 102 SER SER D . n 
C 1 103 VAL 103 103 103 VAL VAL D . n 
C 1 104 ILE 104 104 104 ILE ILE D . n 
C 1 105 SER 105 105 105 SER SER D . n 
C 1 106 LEU 106 106 106 LEU LEU D . n 
C 1 107 SER 107 107 107 SER SER D . n 
C 1 108 GLY 108 108 108 GLY GLY D . n 
C 1 109 ASP 109 109 109 ASP ASP D . n 
C 1 110 HIS 110 110 110 HIS HIS D . n 
C 1 111 CYS 111 111 111 CYS CYS D . n 
C 1 112 ILE 112 112 112 ILE ILE D . n 
C 1 113 ILE 113 113 113 ILE ILE D . n 
C 1 114 GLY 114 114 114 GLY GLY D . n 
C 1 115 ARG 115 115 115 ARG ARG D . n 
C 1 116 THR 116 116 116 THR THR D . n 
C 1 117 LEU 117 117 117 LEU LEU D . n 
C 1 118 VAL 118 118 118 VAL VAL D . n 
C 1 119 VAL 119 119 119 VAL VAL D . n 
C 1 120 HIS 120 120 120 HIS HIS D . n 
C 1 121 GLU 121 121 121 GLU GLU D . n 
C 1 122 LYS 122 122 122 LYS LYS D . n 
C 1 123 ALA 123 123 123 ALA ALA D . n 
C 1 124 ASP 124 124 124 ASP ASP D . n 
C 1 125 ASP 125 125 ?   ?   ?   D . n 
C 1 126 LEU 126 126 ?   ?   ?   D . n 
C 1 127 GLY 127 127 ?   ?   ?   D . n 
C 1 128 LYS 128 128 ?   ?   ?   D . n 
C 1 129 GLY 129 129 ?   ?   ?   D . n 
C 1 130 GLY 130 130 ?   ?   ?   D . n 
C 1 131 ASN 131 131 ?   ?   ?   D . n 
C 1 132 GLU 132 132 ?   ?   ?   D . n 
C 1 133 GLU 133 133 ?   ?   ?   D . n 
C 1 134 SER 134 134 ?   ?   ?   D . n 
C 1 135 THR 135 135 ?   ?   ?   D . n 
C 1 136 LYS 136 136 ?   ?   ?   D . n 
C 1 137 THR 137 137 ?   ?   ?   D . n 
C 1 138 GLY 138 138 ?   ?   ?   D . n 
C 1 139 ASN 139 139 ?   ?   ?   D . n 
C 1 140 ALA 140 140 ?   ?   ?   D . n 
C 1 141 GLY 141 141 141 GLY GLY D . n 
C 1 142 SER 142 142 142 SER SER D . n 
C 1 143 ARG 143 143 143 ARG ARG D . n 
C 1 144 LEU 144 144 144 LEU LEU D . n 
C 1 145 ALA 145 145 145 ALA ALA D . n 
C 1 146 CYS 146 146 146 CYS CYS D . n 
C 1 147 GLY 147 147 147 GLY GLY D . n 
C 1 148 VAL 148 148 148 VAL VAL D . n 
C 1 149 ILE 149 149 149 ILE ILE D . n 
C 1 150 GLY 150 150 150 GLY GLY D . n 
C 1 151 ILE 151 151 151 ILE ILE D . n 
C 1 152 ALA 152 152 152 ALA ALA D . n 
C 1 153 GLN 153 153 153 GLN GLN D . n 
D 1 1   ALA 1   1   1   ALA ALA F . n 
D 1 2   THR 2   2   2   THR THR F . n 
D 1 3   LYS 3   3   3   LYS LYS F . n 
D 1 4   ALA 4   4   4   ALA ALA F . n 
D 1 5   VAL 5   5   5   VAL VAL F . n 
D 1 6   CYS 6   6   6   CYS CYS F . n 
D 1 7   VAL 7   7   7   VAL VAL F . n 
D 1 8   LEU 8   8   8   LEU LEU F . n 
D 1 9   LYS 9   9   9   LYS LYS F . n 
D 1 10  GLY 10  10  10  GLY GLY F . n 
D 1 11  ASP 11  11  11  ASP ASP F . n 
D 1 12  GLY 12  12  12  GLY GLY F . n 
D 1 13  PRO 13  13  13  PRO PRO F . n 
D 1 14  VAL 14  14  14  VAL VAL F . n 
D 1 15  GLN 15  15  15  GLN GLN F . n 
D 1 16  GLY 16  16  16  GLY GLY F . n 
D 1 17  ILE 17  17  17  ILE ILE F . n 
D 1 18  ILE 18  18  18  ILE ILE F . n 
D 1 19  ASN 19  19  19  ASN ASN F . n 
D 1 20  PHE 20  20  20  PHE PHE F . n 
D 1 21  GLU 21  21  21  GLU GLU F . n 
D 1 22  GLN 22  22  22  GLN GLN F . n 
D 1 23  LYS 23  23  23  LYS LYS F . n 
D 1 24  GLU 24  24  24  GLU GLU F . n 
D 1 25  SER 25  25  25  SER SER F . n 
D 1 26  ASN 26  26  26  ASN ASN F . n 
D 1 27  GLY 27  27  27  GLY GLY F . n 
D 1 28  PRO 28  28  28  PRO PRO F . n 
D 1 29  VAL 29  29  29  VAL VAL F . n 
D 1 30  LYS 30  30  30  LYS LYS F . n 
D 1 31  VAL 31  31  31  VAL VAL F . n 
D 1 32  TRP 32  32  32  TRP TRP F . n 
D 1 33  GLY 33  33  33  GLY GLY F . n 
D 1 34  SER 34  34  34  SER SER F . n 
D 1 35  ILE 35  35  35  ILE ILE F . n 
D 1 36  LYS 36  36  36  LYS LYS F . n 
D 1 37  GLY 37  37  37  GLY GLY F . n 
D 1 38  LEU 38  38  38  LEU LEU F . n 
D 1 39  THR 39  39  39  THR THR F . n 
D 1 40  GLU 40  40  40  GLU GLU F . n 
D 1 41  GLY 41  41  41  GLY GLY F . n 
D 1 42  LEU 42  42  42  LEU LEU F . n 
D 1 43  HIS 43  43  43  HIS HIS F . n 
D 1 44  GLY 44  44  44  GLY GLY F . n 
D 1 45  PHE 45  45  45  PHE PHE F . n 
D 1 46  HIS 46  46  46  HIS HIS F . n 
D 1 47  VAL 47  47  47  VAL VAL F . n 
D 1 48  HIS 48  48  48  HIS HIS F . n 
D 1 49  GLU 49  49  49  GLU GLU F . n 
D 1 50  PHE 50  50  50  PHE PHE F . n 
D 1 51  GLY 51  51  51  GLY GLY F . n 
D 1 52  ASP 52  52  52  ASP ASP F . n 
D 1 53  ASN 53  53  53  ASN ASN F . n 
D 1 54  THR 54  54  54  THR THR F . n 
D 1 55  ALA 55  55  55  ALA ALA F . n 
D 1 56  GLY 56  56  56  GLY GLY F . n 
D 1 57  CYS 57  57  57  CYS CYS F . n 
D 1 58  THR 58  58  58  THR THR F . n 
D 1 59  SER 59  59  59  SER SER F . n 
D 1 60  ALA 60  60  60  ALA ALA F . n 
D 1 61  GLY 61  61  61  GLY GLY F . n 
D 1 62  PRO 62  62  62  PRO PRO F . n 
D 1 63  HIS 63  63  63  HIS HIS F . n 
D 1 64  PHE 64  64  64  PHE PHE F . n 
D 1 65  ASN 65  65  65  ASN ASN F . n 
D 1 66  PRO 66  66  66  PRO PRO F . n 
D 1 67  LEU 67  67  67  LEU LEU F . n 
D 1 68  SER 68  68  ?   ?   ?   F . n 
D 1 69  ARG 69  69  ?   ?   ?   F . n 
D 1 70  LYS 70  70  ?   ?   ?   F . n 
D 1 71  HIS 71  71  ?   ?   ?   F . n 
D 1 72  GLY 72  72  ?   ?   ?   F . n 
D 1 73  GLY 73  73  ?   ?   ?   F . n 
D 1 74  PRO 74  74  ?   ?   ?   F . n 
D 1 75  LYS 75  75  ?   ?   ?   F . n 
D 1 76  ASP 76  76  ?   ?   ?   F . n 
D 1 77  GLU 77  77  ?   ?   ?   F . n 
D 1 78  GLU 78  78  ?   ?   ?   F . n 
D 1 79  ARG 79  79  79  ARG ARG F . n 
D 1 80  HIS 80  80  80  HIS HIS F . n 
D 1 81  VAL 81  81  81  VAL VAL F . n 
D 1 82  GLY 82  82  82  GLY GLY F . n 
D 1 83  ASP 83  83  83  ASP ASP F . n 
D 1 84  LEU 84  84  84  LEU LEU F . n 
D 1 85  GLY 85  85  85  GLY GLY F . n 
D 1 86  ASN 86  86  86  ASN ASN F . n 
D 1 87  VAL 87  87  87  VAL VAL F . n 
D 1 88  THR 88  88  88  THR THR F . n 
D 1 89  ALA 89  89  89  ALA ALA F . n 
D 1 90  ASP 90  90  90  ASP ASP F . n 
D 1 91  LYS 91  91  91  LYS LYS F . n 
D 1 92  ASP 92  92  92  ASP ASP F . n 
D 1 93  GLY 93  93  93  GLY GLY F . n 
D 1 94  VAL 94  94  94  VAL VAL F . n 
D 1 95  ALA 95  95  95  ALA ALA F . n 
D 1 96  ASP 96  96  96  ASP ASP F . n 
D 1 97  VAL 97  97  97  VAL VAL F . n 
D 1 98  SER 98  98  98  SER SER F . n 
D 1 99  ILE 99  99  99  ILE ILE F . n 
D 1 100 GLU 100 100 100 GLU GLU F . n 
D 1 101 ASP 101 101 101 ASP ASP F . n 
D 1 102 SER 102 102 102 SER SER F . n 
D 1 103 VAL 103 103 103 VAL VAL F . n 
D 1 104 ILE 104 104 104 ILE ILE F . n 
D 1 105 SER 105 105 105 SER SER F . n 
D 1 106 LEU 106 106 106 LEU LEU F . n 
D 1 107 SER 107 107 107 SER SER F . n 
D 1 108 GLY 108 108 108 GLY GLY F . n 
D 1 109 ASP 109 109 109 ASP ASP F . n 
D 1 110 HIS 110 110 110 HIS HIS F . n 
D 1 111 CYS 111 111 111 CYS CYS F . n 
D 1 112 ILE 112 112 112 ILE ILE F . n 
D 1 113 ILE 113 113 113 ILE ILE F . n 
D 1 114 GLY 114 114 114 GLY GLY F . n 
D 1 115 ARG 115 115 115 ARG ARG F . n 
D 1 116 THR 116 116 116 THR THR F . n 
D 1 117 LEU 117 117 117 LEU LEU F . n 
D 1 118 VAL 118 118 118 VAL VAL F . n 
D 1 119 VAL 119 119 119 VAL VAL F . n 
D 1 120 HIS 120 120 120 HIS HIS F . n 
D 1 121 GLU 121 121 121 GLU GLU F . n 
D 1 122 LYS 122 122 122 LYS LYS F . n 
D 1 123 ALA 123 123 123 ALA ALA F . n 
D 1 124 ASP 124 124 124 ASP ASP F . n 
D 1 125 ASP 125 125 ?   ?   ?   F . n 
D 1 126 LEU 126 126 ?   ?   ?   F . n 
D 1 127 GLY 127 127 ?   ?   ?   F . n 
D 1 128 LYS 128 128 ?   ?   ?   F . n 
D 1 129 GLY 129 129 ?   ?   ?   F . n 
D 1 130 GLY 130 130 ?   ?   ?   F . n 
D 1 131 ASN 131 131 ?   ?   ?   F . n 
D 1 132 GLU 132 132 ?   ?   ?   F . n 
D 1 133 GLU 133 133 ?   ?   ?   F . n 
D 1 134 SER 134 134 ?   ?   ?   F . n 
D 1 135 THR 135 135 ?   ?   ?   F . n 
D 1 136 LYS 136 136 ?   ?   ?   F . n 
D 1 137 THR 137 137 ?   ?   ?   F . n 
D 1 138 GLY 138 138 ?   ?   ?   F . n 
D 1 139 ASN 139 139 ?   ?   ?   F . n 
D 1 140 ALA 140 140 ?   ?   ?   F . n 
D 1 141 GLY 141 141 141 GLY GLY F . n 
D 1 142 SER 142 142 142 SER SER F . n 
D 1 143 ARG 143 143 143 ARG ARG F . n 
D 1 144 LEU 144 144 144 LEU LEU F . n 
D 1 145 ALA 145 145 145 ALA ALA F . n 
D 1 146 CYS 146 146 146 CYS CYS F . n 
D 1 147 GLY 147 147 147 GLY GLY F . n 
D 1 148 VAL 148 148 148 VAL VAL F . n 
D 1 149 ILE 149 149 149 ILE ILE F . n 
D 1 150 GLY 150 150 150 GLY GLY F . n 
D 1 151 ILE 151 151 151 ILE ILE F . n 
D 1 152 ALA 152 152 152 ALA ALA F . n 
D 1 153 GLN 153 153 153 GLN GLN F . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 2 D7Z 1 201 1 D7Z PTI A . 
F 2 D7Z 1 201 1 D7Z PTI B . 
G 2 D7Z 1 201 1 D7Z PTI D . 
H 2 D7Z 1 201 1 D7Z PTI F . 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA dimeric 2 
2 author_and_software_defined_assembly PISA dimeric 2 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,B,E,F 
2 1 C,D,G,H 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 1640  ? 
1 MORE         -13   ? 
1 'SSA (A^2)'  14180 ? 
2 'ABSA (A^2)' 1640  ? 
2 MORE         -13   ? 
2 'SSA (A^2)'  11900 ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  SG ? A CYS 111 ? A CYS 111 ? 1_555 PT8 ? E D7Z . ? A D7Z 201 ? 1_555 N1  ? E D7Z . ? A D7Z 201 ? 1_555 97.7  ? 
2  SG ? A CYS 111 ? A CYS 111 ? 1_555 PT8 ? E D7Z . ? A D7Z 201 ? 1_555 N2  ? E D7Z . ? A D7Z 201 ? 1_555 119.5 ? 
3  N1 ? E D7Z .   ? A D7Z 201 ? 1_555 PT8 ? E D7Z . ? A D7Z 201 ? 1_555 N2  ? E D7Z . ? A D7Z 201 ? 1_555 87.2  ? 
4  SG ? A CYS 111 ? A CYS 111 ? 1_555 PT8 ? E D7Z . ? A D7Z 201 ? 1_555 CL1 ? E D7Z . ? A D7Z 201 ? 1_555 84.3  ? 
5  N1 ? E D7Z .   ? A D7Z 201 ? 1_555 PT8 ? E D7Z . ? A D7Z 201 ? 1_555 CL1 ? E D7Z . ? A D7Z 201 ? 1_555 177.8 ? 
6  N2 ? E D7Z .   ? A D7Z 201 ? 1_555 PT8 ? E D7Z . ? A D7Z 201 ? 1_555 CL1 ? E D7Z . ? A D7Z 201 ? 1_555 91.0  ? 
7  SG ? B CYS 111 ? B CYS 111 ? 1_555 PT8 ? F D7Z . ? B D7Z 201 ? 1_555 N1  ? F D7Z . ? B D7Z 201 ? 1_555 95.5  ? 
8  SG ? B CYS 111 ? B CYS 111 ? 1_555 PT8 ? F D7Z . ? B D7Z 201 ? 1_555 N2  ? F D7Z . ? B D7Z 201 ? 1_555 113.4 ? 
9  N1 ? F D7Z .   ? B D7Z 201 ? 1_555 PT8 ? F D7Z . ? B D7Z 201 ? 1_555 N2  ? F D7Z . ? B D7Z 201 ? 1_555 87.0  ? 
10 SG ? B CYS 111 ? B CYS 111 ? 1_555 PT8 ? F D7Z . ? B D7Z 201 ? 1_555 CL1 ? F D7Z . ? B D7Z 201 ? 1_555 85.7  ? 
11 N1 ? F D7Z .   ? B D7Z 201 ? 1_555 PT8 ? F D7Z . ? B D7Z 201 ? 1_555 CL1 ? F D7Z . ? B D7Z 201 ? 1_555 178.6 ? 
12 N2 ? F D7Z .   ? B D7Z 201 ? 1_555 PT8 ? F D7Z . ? B D7Z 201 ? 1_555 CL1 ? F D7Z . ? B D7Z 201 ? 1_555 92.0  ? 
13 SG ? C CYS 111 ? D CYS 111 ? 1_555 PT8 ? G D7Z . ? D D7Z 201 ? 1_555 N1  ? G D7Z . ? D D7Z 201 ? 1_555 94.0  ? 
14 SG ? C CYS 111 ? D CYS 111 ? 1_555 PT8 ? G D7Z . ? D D7Z 201 ? 1_555 N2  ? G D7Z . ? D D7Z 201 ? 1_555 117.2 ? 
15 N1 ? G D7Z .   ? D D7Z 201 ? 1_555 PT8 ? G D7Z . ? D D7Z 201 ? 1_555 N2  ? G D7Z . ? D D7Z 201 ? 1_555 87.1  ? 
16 SG ? C CYS 111 ? D CYS 111 ? 1_555 PT8 ? G D7Z . ? D D7Z 201 ? 1_555 CL1 ? G D7Z . ? D D7Z 201 ? 1_555 88.6  ? 
17 N1 ? G D7Z .   ? D D7Z 201 ? 1_555 PT8 ? G D7Z . ? D D7Z 201 ? 1_555 CL1 ? G D7Z . ? D D7Z 201 ? 1_555 177.3 ? 
18 N2 ? G D7Z .   ? D D7Z 201 ? 1_555 PT8 ? G D7Z . ? D D7Z 201 ? 1_555 CL1 ? G D7Z . ? D D7Z 201 ? 1_555 92.3  ? 
19 SG ? D CYS 111 ? F CYS 111 ? 1_555 PT8 ? H D7Z . ? F D7Z 201 ? 1_555 N1  ? H D7Z . ? F D7Z 201 ? 1_555 93.7  ? 
20 SG ? D CYS 111 ? F CYS 111 ? 1_555 PT8 ? H D7Z . ? F D7Z 201 ? 1_555 N2  ? H D7Z . ? F D7Z 201 ? 1_555 124.2 ? 
21 N1 ? H D7Z .   ? F D7Z 201 ? 1_555 PT8 ? H D7Z . ? F D7Z 201 ? 1_555 N2  ? H D7Z . ? F D7Z 201 ? 1_555 86.8  ? 
22 SG ? D CYS 111 ? F CYS 111 ? 1_555 PT8 ? H D7Z . ? F D7Z 201 ? 1_555 CL1 ? H D7Z . ? F D7Z 201 ? 1_555 88.0  ? 
23 N1 ? H D7Z .   ? F D7Z 201 ? 1_555 PT8 ? H D7Z . ? F D7Z 201 ? 1_555 CL1 ? H D7Z . ? F D7Z 201 ? 1_555 178.3 ? 
24 N2 ? H D7Z .   ? F D7Z 201 ? 1_555 PT8 ? H D7Z . ? F D7Z 201 ? 1_555 CL1 ? H D7Z . ? F D7Z 201 ? 1_555 92.3  ? 
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2018-11-28 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
# 
loop_
_pdbx_refine_tls.pdbx_refine_id 
_pdbx_refine_tls.id 
_pdbx_refine_tls.details 
_pdbx_refine_tls.method 
_pdbx_refine_tls.origin_x 
_pdbx_refine_tls.origin_y 
_pdbx_refine_tls.origin_z 
_pdbx_refine_tls.T[1][1] 
_pdbx_refine_tls.T[2][2] 
_pdbx_refine_tls.T[3][3] 
_pdbx_refine_tls.T[1][2] 
_pdbx_refine_tls.T[1][3] 
_pdbx_refine_tls.T[2][3] 
_pdbx_refine_tls.L[1][1] 
_pdbx_refine_tls.L[2][2] 
_pdbx_refine_tls.L[3][3] 
_pdbx_refine_tls.L[1][2] 
_pdbx_refine_tls.L[1][3] 
_pdbx_refine_tls.L[2][3] 
_pdbx_refine_tls.S[1][1] 
_pdbx_refine_tls.S[1][2] 
_pdbx_refine_tls.S[1][3] 
_pdbx_refine_tls.S[2][1] 
_pdbx_refine_tls.S[2][2] 
_pdbx_refine_tls.S[2][3] 
_pdbx_refine_tls.S[3][1] 
_pdbx_refine_tls.S[3][2] 
_pdbx_refine_tls.S[3][3] 
'X-RAY DIFFRACTION' 1 ? refined 13.0627  -17.8180 -20.7048 0.0919 0.6920 0.0400 0.0378 -0.0121 0.0012  2.2267 1.2070 5.1271 
-0.2189 -0.0450 -0.3744 0.0406  -0.2955 -0.2289 0.1169  -0.1273 0.0333  0.2738  0.2316  0.0868  
'X-RAY DIFFRACTION' 2 ? refined 3.8276   -11.8408 -46.3592 0.0627 0.8157 0.0265 0.0611 -0.0121 -0.0176 2.7525 1.1106 3.9817 0.1855 
0.2617  0.1228  0.0216  0.6566  0.1347  -0.0513 0.1000  0.0233  -0.0891 -0.2653 -0.1216 
'X-RAY DIFFRACTION' 3 ? refined -22.0225 -12.1999 -7.4932  0.0822 0.6381 0.0066 0.0666 -0.0236 0.0383  4.0608 2.7983 6.2547 
-0.4219 1.1927  -0.6083 -0.0542 -0.5658 -0.2135 0.2002  0.0407  -0.0682 0.2926  -0.0782 0.0135  
'X-RAY DIFFRACTION' 4 ? refined -29.1056 -0.8913  -31.9538 0.1013 0.7743 0.0504 0.1558 -0.0103 0.0415  3.5938 1.6898 6.5246 
-0.5294 -0.3074 -0.5840 0.1125  0.6495  0.3213  -0.0592 -0.0762 -0.0709 -0.4511 -0.4979 -0.0363 
# 
loop_
_pdbx_refine_tls_group.pdbx_refine_id 
_pdbx_refine_tls_group.id 
_pdbx_refine_tls_group.refine_tls_id 
_pdbx_refine_tls_group.beg_auth_asym_id 
_pdbx_refine_tls_group.beg_auth_seq_id 
_pdbx_refine_tls_group.beg_label_asym_id 
_pdbx_refine_tls_group.beg_label_seq_id 
_pdbx_refine_tls_group.end_auth_asym_id 
_pdbx_refine_tls_group.end_auth_seq_id 
_pdbx_refine_tls_group.end_label_asym_id 
_pdbx_refine_tls_group.end_label_seq_id 
_pdbx_refine_tls_group.selection 
_pdbx_refine_tls_group.selection_details 
'X-RAY DIFFRACTION' 1 1 ? ? ? ? ? ? ? ? ? '{ A|1 - A|153 }' 
'X-RAY DIFFRACTION' 2 2 ? ? ? ? ? ? ? ? ? '{ B|1 - B|153 }' 
'X-RAY DIFFRACTION' 3 3 ? ? ? ? ? ? ? ? ? '{ D|1 - D|153 }' 
'X-RAY DIFFRACTION' 4 4 ? ? ? ? ? ? ? ? ? '{ F|1 - F|153 }' 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? BUSTER ? ? ? 2.10.3 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .      2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XSCALE ? ? ? .      3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? MOLREP ? ? ? .      4 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 SER A 98 ? ? -150.83 85.51   
2 1 ASP B 90 ? ? -74.47  -169.92 
3 1 ASN D 26 ? ? -95.88  34.72   
4 1 ASP F 83 ? ? -68.75  95.79   
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 D SER 68  ? C SER 68  
2  1 Y 1 D ARG 69  ? C ARG 69  
3  1 Y 1 D LYS 70  ? C LYS 70  
4  1 Y 1 D HIS 71  ? C HIS 71  
5  1 Y 1 D GLY 72  ? C GLY 72  
6  1 Y 1 D GLY 73  ? C GLY 73  
7  1 Y 1 D PRO 74  ? C PRO 74  
8  1 Y 1 D LYS 75  ? C LYS 75  
9  1 Y 1 D ASP 76  ? C ASP 76  
10 1 Y 1 D GLU 77  ? C GLU 77  
11 1 Y 1 D GLU 78  ? C GLU 78  
12 1 Y 1 D ASP 125 ? C ASP 125 
13 1 Y 1 D LEU 126 ? C LEU 126 
14 1 Y 1 D GLY 127 ? C GLY 127 
15 1 Y 1 D LYS 128 ? C LYS 128 
16 1 Y 1 D GLY 129 ? C GLY 129 
17 1 Y 1 D GLY 130 ? C GLY 130 
18 1 Y 1 D ASN 131 ? C ASN 131 
19 1 Y 1 D GLU 132 ? C GLU 132 
20 1 Y 1 D GLU 133 ? C GLU 133 
21 1 Y 1 D SER 134 ? C SER 134 
22 1 Y 1 D THR 135 ? C THR 135 
23 1 Y 1 D LYS 136 ? C LYS 136 
24 1 Y 1 D THR 137 ? C THR 137 
25 1 Y 1 D GLY 138 ? C GLY 138 
26 1 Y 1 D ASN 139 ? C ASN 139 
27 1 Y 1 D ALA 140 ? C ALA 140 
28 1 Y 1 F SER 68  ? D SER 68  
29 1 Y 1 F ARG 69  ? D ARG 69  
30 1 Y 1 F LYS 70  ? D LYS 70  
31 1 Y 1 F HIS 71  ? D HIS 71  
32 1 Y 1 F GLY 72  ? D GLY 72  
33 1 Y 1 F GLY 73  ? D GLY 73  
34 1 Y 1 F PRO 74  ? D PRO 74  
35 1 Y 1 F LYS 75  ? D LYS 75  
36 1 Y 1 F ASP 76  ? D ASP 76  
37 1 Y 1 F GLU 77  ? D GLU 77  
38 1 Y 1 F GLU 78  ? D GLU 78  
39 1 Y 1 F ASP 125 ? D ASP 125 
40 1 Y 1 F LEU 126 ? D LEU 126 
41 1 Y 1 F GLY 127 ? D GLY 127 
42 1 Y 1 F LYS 128 ? D LYS 128 
43 1 Y 1 F GLY 129 ? D GLY 129 
44 1 Y 1 F GLY 130 ? D GLY 130 
45 1 Y 1 F ASN 131 ? D ASN 131 
46 1 Y 1 F GLU 132 ? D GLU 132 
47 1 Y 1 F GLU 133 ? D GLU 133 
48 1 Y 1 F SER 134 ? D SER 134 
49 1 Y 1 F THR 135 ? D THR 135 
50 1 Y 1 F LYS 136 ? D LYS 136 
51 1 Y 1 F THR 137 ? D THR 137 
52 1 Y 1 F GLY 138 ? D GLY 138 
53 1 Y 1 F ASN 139 ? D ASN 139 
54 1 Y 1 F ALA 140 ? D ALA 140 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        'PtCl2(1(R),2(R)-DACH)' 
_pdbx_entity_nonpoly.comp_id     D7Z 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
